| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Seung Woo Chung, Taslim A Hil-lal, Youngro Byu. Strategies for non-invasive delivery of biologics. Journal of drug targeting. vol 20. issue 6. 2012-10-26. PMID:22632037. |
insulin, calcitonin and heparin were mainly focused for the discussion as they could represent protein, polypeptide and polysaccharide drugs, respectively. |
2012-10-26 |
2023-08-12 |
Not clear |
| John Howl, Sabine Matou-Nasri, David C West, Michelle Farquhar, Jiřina Slaninová, Claes-Göran Ostenson, Matjaz Zorko, Pernilla Ostlund, Shant Kumar, Ulo Langel, Jane McKeating, Sarah Jone. Bioportide: an emergent concept of bioactive cell-penetrating peptides. Cellular and molecular life sciences : CMLS. vol 69. issue 17. 2012-10-23. PMID:22527714. |
thus, camptide, a cell-penetrant sequence located within the first intracellular loop of a human calcitonin receptor, regulates camp-dependent processes to modulate insulin secretion and viral infectivity. |
2012-10-23 |
2023-08-12 |
human |
| M Al-Hariri, T Gamal Eldin, B Abu-Hozaifa, A Elnou. Glycemic control and anti-osteopathic effect of propolis in diabetic rats. Diabetes, metabolic syndrome and obesity : targets and therapy. vol 4. 2012-10-02. PMID:22253535. |
fasting blood glucose (fbg), plasma insulin and glucagon, serum thiobarbituric acid reactive substances (tbars), plasma parathyroid hormone (pth), and calcitonin levels were also estimated and analyzed. |
2012-10-02 |
2023-08-12 |
rat |
| Chang Hyun Lee, Dae-Keun Kim, Tae-Han Yook, Motoki Sasaki, Nobuo Kitamur. Effectiveness of electroacupuncture at Zusanli (ST36) on the immunohistochemical density of enteroendocrine cells related to gastrointestinal function. Journal of acupuncture and meridian studies. vol 5. issue 2. 2012-07-31. PMID:22483184. |
the authors investigated the histochemical changes of mucous substances and immunohistochemical density of gastrin, serotonin, calcitonin gene-related peptide (cgrp), insulin, and pancreatic polypeptide (pp) secreting cells in rats. |
2012-07-31 |
2023-08-12 |
rat |
| Antonis Polymeris, Peter D Papapetrou, Fotini Papandroulaki, Stavroula Thano. Hyperinsulinemia during oral glucose tolerance test and high normal serum cortisol are associated with increased secretion of calcitonin in normal subjects. Hormones (Athens, Greece). vol 10. issue 4. 2012-05-24. PMID:22281887. |
previous studies showed that insulin stimulated directly calcitonin (ct) secretion in the pig thyroid, while dexamethasone stimulated the production of ct and ct mrna in medullary thyroid carcinoma (mtc) cell lines. |
2012-05-24 |
2023-08-12 |
human |
| Eric P Davidson, Lawrence J Coppey, Amey Holmes, Brian Dake, Mark A Yore. Effect of treatment of high fat fed/low dose streptozotocin-diabetic rats with Ilepatril on vascular and neural complications. European journal of pharmacology. vol 668. issue 3. 2012-01-19. PMID:21816138. |
diabetic and diet induced obese rats have characteristics of insulin resistance, slowing of nerve conduction velocity, thermal hypoalgesia, reduction in intraepidermal nerve fiber density in the hindpaw and impairment in vascular relaxation to acetylcholine and calcitonin gene-related peptide in epineurial arterioles of the sciatic nerve. |
2012-01-19 |
2023-08-12 |
rat |
| M Feigh, K Henriksen, K V Andreassen, C Hansen, J E Henriksen, H Beck-Nielsen, C Christiansen, M A Karsda. A novel oral form of salmon calcitonin improves glucose homeostasis and reduces body weight in diet-induced obese rats. Diabetes, obesity & metabolism. vol 13. issue 10. 2011-12-07. PMID:21615667. |
to investigate the effects of acute and chronic administration of a novel oral formulation of salmon calcitonin (sct) on glycaemic control, glucose homeostasis and body weight regulation in diet-induced obese (dio) rats-an animal model of obesity-related insulin resistance and type 2 diabetes. |
2011-12-07 |
2023-08-12 |
rat |
| Zhengqi Dong, Khuriah Abdul Hamid, Yang Gao, Yulian Lin, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamot. Polyamidoamine dendrimers can improve the pulmonary absorption of insulin and calcitonin in rats. Journal of pharmaceutical sciences. vol 100. issue 5. 2011-06-14. PMID:21374620. |
polyamidoamine dendrimers can improve the pulmonary absorption of insulin and calcitonin in rats. |
2011-06-14 |
2023-08-12 |
rat |
| Zhengqi Dong, Khuriah Abdul Hamid, Yang Gao, Yulian Lin, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamot. Polyamidoamine dendrimers can improve the pulmonary absorption of insulin and calcitonin in rats. Journal of pharmaceutical sciences. vol 100. issue 5. 2011-06-14. PMID:21374620. |
insulin and calcitonin were chosen as models of peptide and protein drugs, and their pulmonary absorption with or without pamam dendrimers was examined by in vivo pulmonary absorption studies. |
2011-06-14 |
2023-08-12 |
rat |
| Zhengqi Dong, Khuriah Abdul Hamid, Yang Gao, Yulian Lin, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamot. Polyamidoamine dendrimers can improve the pulmonary absorption of insulin and calcitonin in rats. Journal of pharmaceutical sciences. vol 100. issue 5. 2011-06-14. PMID:21374620. |
pamam dendrimers significantly increased the pulmonary absorption of insulin and calcitonin in rats, and their absorption-enhancing effects were generation dependent. |
2011-06-14 |
2023-08-12 |
rat |
| Zhengqi Dong, Khuriah Abdul Hamid, Yang Gao, Yulian Lin, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamot. Polyamidoamine dendrimers can improve the pulmonary absorption of insulin and calcitonin in rats. Journal of pharmaceutical sciences. vol 100. issue 5. 2011-06-14. PMID:21374620. |
the zeta potentials of insulin and calcitonin solutions changed to positive by the addition of pamam dendrimers, and the degree of positive charge as determined by the zeta potentials was linearly correlated with the absorption-enhancing effects of the pamam dendrimers. |
2011-06-14 |
2023-08-12 |
rat |
| Zhengqi Dong, Khuriah Abdul Hamid, Yang Gao, Yulian Lin, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamot. Polyamidoamine dendrimers can improve the pulmonary absorption of insulin and calcitonin in rats. Journal of pharmaceutical sciences. vol 100. issue 5. 2011-06-14. PMID:21374620. |
this positive charge of the pamam dendrimers might be related to their absorption-enhancing mechanisms for improving the pulmonary absorption of insulin and calcitonin in rats. |
2011-06-14 |
2023-08-12 |
rat |
| Zhengqi Dong, Khuriah Abdul Hamid, Yang Gao, Yulian Lin, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamot. Polyamidoamine dendrimers can improve the pulmonary absorption of insulin and calcitonin in rats. Journal of pharmaceutical sciences. vol 100. issue 5. 2011-06-14. PMID:21374620. |
in conclusion, the pamam dendrimers are suitable absorption enhancers to improve the pulmonary absorption of insulin and calcitonin without any membrane damage to the respiratory tissues. |
2011-06-14 |
2023-08-12 |
rat |
| S S Butakova, A D Nozdrache. Mechanisms of hyperglycemic effect of calcitonin. Bulletin of experimental biology and medicine. vol 150. issue 3. 2011-05-20. PMID:21240344. |
we studied the effect of calcitonin on blood glucose level, total calcium content, and the main stages of carbohydrate metabolism: absorption in the intestine, transport from the blood to tissues, tissue sensitivity to insulin in the whole organism, glycogen content, and activity of glucose-6-phosphate dehydrogenase and lactate dehydrogenase in the liver. |
2011-05-20 |
2023-08-12 |
Not clear |
| Hirotsugu Tanaka, Akiyoshi Shimaya, Tetsuo Kiso, Takahiro Kuramochi, Teruhiko Shimokawa, Masayuki Shibasak. Enhanced insulin secretion and sensitization in diabetic mice on chronic treatment with a transient receptor potential vanilloid 1 antagonist. Life sciences. vol 88. issue 11-12. 2011-05-06. PMID:21277869. |
inhibition of transient receptor potential vanilloid 1 (trpv1) suppresses calcitonin gene-related peptide (cgrp) secretion in pancreatic nerve fiber cells, thereby stimulating insulin secretion. |
2011-05-06 |
2023-08-12 |
mouse |
| Yulian Lin, Takeo Fujimori, Naoko Kawaguchi, Yuiko Tsujimoto, Mariko Nishimi, Zhengqi Dong, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamot. Polyamidoamine dendrimers as novel potential absorption enhancers for improving the small intestinal absorption of poorly absorbable drugs in rats. Journal of controlled release : official journal of the Controlled Release Society. vol 149. issue 1. 2011-04-28. PMID:20184931. |
5(6)-carboxyfluorescein (cf), fluorescein isothiocyanate-dextrans (fds) with various molecular weights, calcitonin and insulin were used as model drugs of poorly absorbable drugs. |
2011-04-28 |
2023-08-12 |
rat |
| Masayoshi Yamaguch. The transcriptional regulation of regucalcin gene expression. Molecular and cellular biochemistry. vol 346. issue 1-2. 2011-04-08. PMID:20936536. |
the expression of regucalcin mrna in the liver and kidney cortex has been shown to stimulate by hormonal factors (including calcium, calcitonin, parathyroid hormone, insulin, estrogen, and dexamethasone) in vivo. |
2011-04-08 |
2023-08-12 |
human |
| S S Butakova, A D Nozdrache. [Calcitonin--contra-insulin hormone]. Advances in gerontology = Uspekhi gerontologii. vol 23. issue 3. 2010-12-23. PMID:21137206. |
some arguments of antagonistic calcitonin effect to insulin under the pre-receptor, cell level and liver were done. |
2010-12-23 |
2023-08-12 |
Not clear |
| S S Butakova, A D Nozdrache. [Calcitonin--contra-insulin hormone]. Advances in gerontology = Uspekhi gerontologii. vol 23. issue 3. 2010-12-23. PMID:21137206. |
the impairment of glucose metabolism under calcitonin is established--hyperglycemia, insulin resistance and glucose intolerance. |
2010-12-23 |
2023-08-12 |
Not clear |
| G Peros, G H Sakorafas, G Konstantoudakis, G A Giannopoulos, K Petropoulou, A Paras. Duodeno-pancreatic neuroendocrine tumours. European journal of cancer care. vol 19. issue 3. 2010-10-29. PMID:19708940. |
histological/immunohistochemical diagnosis was somatostatin-producing tumour in the first patient, oncocytic endocrine tumour positive for neurone-specific enolase and focally for chromogranin in the second patient, glucagonoma and pancreatic polypeptide-producing endocrine pancreatic tumour in the third patient, and gastrin, somatostatin, calcitonin, insulin and adrenocorticotropic hormone (acth)-producing tumour in the fourth. |
2010-10-29 |
2023-08-12 |
Not clear |