| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jan Ortmann, Elke Doberentz, Burkhard Made. Immunohistochemical methods as an aid in estimating the time since death. Forensic science international. vol 273. 2018-05-30. PMID:28236731. |
a systematic analysis (wehner et al., 1999-2002) demonstrated that calcitonin can still be stained 4 days, thyreoglobulin 5 days, glucagon 6 days, and insulin 12 days after death. |
2018-05-30 |
2023-08-13 |
Not clear |
| Jan Ortmann, Elke Doberentz, Burkhard Made. Immunohistochemical methods as an aid in estimating the time since death. Forensic science international. vol 273. 2018-05-30. PMID:28236731. |
after 12 days, calcitonin and thyroglobulin can no longer be stained, glucagon after 14 days, and insulin after 29 days. |
2018-05-30 |
2023-08-13 |
Not clear |
| Jan Ortmann, Elke Doberentz, Burkhard Made. Immunohistochemical methods as an aid in estimating the time since death. Forensic science international. vol 273. 2018-05-30. PMID:28236731. |
pancreatic tissue was stained for insulin and glucagon, and the thyroid gland for thyreoglobulin and calcitonin. |
2018-05-30 |
2023-08-13 |
Not clear |
| Alexander Bartelt, Anke Jeschke, Brigitte Müller, Isabella Gaziano, Michelle Morales, Timur Yorgan, Timo Heckt, Markus Heine, Robert F Gagel, Ronald B Emeson, Michael Amling, Andreas Niemeier, Jörg Heeren, Thorsten Schinke, Johannes Kelle. Differential effects of Calca-derived peptides in male mice with diet-induced obesity. PloS one. vol 12. issue 6. 2017-10-06. PMID:28666011. |
key metabolic hormones, such as insulin, leptin, and adiponectin, have been studied extensively in obesity, however the pathophysiologic relevance of the calcitonin family of peptides remains unclear. |
2017-10-06 |
2023-08-13 |
mouse |
| Sara T Hjuler, Sofie Gydesen, Kim V Andreassen, Morten A Karsdal, Kim Henrikse. The Dual Amylin- and Calcitonin-Receptor Agonist KBP-042 Works as Adjunct to Metformin on Fasting Hyperglycemia and HbA1c in a Rat Model of Type 2 Diabetes. The Journal of pharmacology and experimental therapeutics. vol 362. issue 1. 2017-06-21. PMID:28438778. |
kbp-042 is a dual amylin and calcitonin receptor agonist that increases glucose tolerance and insulin action and reduces body weight in rat models of obesity and prediabetes. |
2017-06-21 |
2023-08-13 |
rat |
| Abhaya Krishnan, Sridhar Muthusam. Hormonal alterations in PCOS and its influence on bone metabolism. The Journal of endocrinology. vol 232. issue 2. 2017-06-14. PMID:27895088. |
hormones, which include gonadotrophin-releasing hormone (gnrh), insulin, the leutinizing/follicle-stimulating hormone (lh/fsh) ratio, androgens, estrogens, growth hormones (gh), cortisol, parathyroid hormone (pth) and calcitonin are disturbed in pcos women. |
2017-06-14 |
2023-08-13 |
human |
| Mona M A Abdel-Mottaleb, Alf Lamprech. In vivo skin penetration of macromolecules in irritant contact dermatitis. International journal of pharmaceutics. vol 515. issue 1-2. 2017-04-19. PMID:27771484. |
results revealed that the transdermal permeation of insulin and calcitonin was not significantly enhanced in dermatitis compared to healthy skin. |
2017-04-19 |
2023-08-13 |
mouse |
| Marianne Lindblad, Anders Hougaard, Faisal Mohammad Amin, Messoud Ashin. Can migraine aura be provoked experimentally? A systematic review of potential methods for the provocation of migraine aura. Cephalalgia : an international journal of headache. vol 37. issue 1. 2017-03-10. PMID:26946372. |
in the prospective studies, aura were reported following the administration of intravenous and sublingual glyceryl trinitrate, visual stimulation, physical activity, calcitonin gene-related peptide infusion, chocolate ingestion, and the intravenous injection of insulin. |
2017-03-10 |
2023-08-13 |
Not clear |
| Takayasu Kawasaki, Gaku Ohori, Tomoyuki Chiba, Koichi Tsukiyama, Kazuhiro Nakamur. Picosecond pulsed infrared laser tuned to amide I band dissociates polyglutamine fibrils in cells. Lasers in medical science. vol 31. issue 7. 2017-01-02. PMID:27342599. |
we recently found that a free electron laser (fel), which has an oscillation wavelength at the amide i band (c = o stretch vibration mode) and picosecond pulse width, was effective for conversion of the fibril forms of insulin, lysozyme, and calcitonin peptide into their monomer forms. |
2017-01-02 |
2023-08-13 |
Not clear |
| Nada Matougui, Lukas Boge, Anne-Claire Groo, Anita Umerska, Lovisa Ringstad, Helena Bysell, Patrick Saulnie. Lipid-based nanoformulations for peptide delivery. International journal of pharmaceutics. vol 502. issue 1-2. 2016-12-13. PMID:26899976. |
important peptides such as insulin, calcitonin and cyclosporin a have been incorporated into lnfs. |
2016-12-13 |
2023-08-13 |
Not clear |
| Marisol Soria, Miguel Anson, Jesús F Escaner. Correlation Analysis of Exercise-Induced Changes in Plasma Trace Element and Hormone Levels During Incremental Exercise in Well-Trained Athletes. Biological trace element research. vol 170. issue 1. 2016-10-28. PMID:26271307. |
whole blood lactate concentration and plasma concentrations of ions (zn, se, mn, and co), insulin, glucagon, aldosterone, thyroid stimulating hormone (tsh), calcitonin, and parathyroid hormone (pth) were measured at rest; at the end of each stage; and 3, 5, and 7 min post-exercise. |
2016-10-28 |
2023-08-13 |
Not clear |
| Pegah Varamini, Istvan Tot. Recent advances in oral delivery of peptide hormones. Expert opinion on drug delivery. vol 13. issue 4. 2016-10-12. PMID:26787260. |
due to increasing demand for oral delivery of peptide hormones such as insulin, gonadotropin-releasing hormones, and calcitonin, various technologies have been explored to overcome the associated hurdles. |
2016-10-12 |
2023-08-13 |
Not clear |
| Sonia Martínez-Herrero, Ignacio M Larrayoz, Laura Ochoa-Callejero, Luis J Fernández, Alexis Allueva, Ignacio Ochoa, Alfredo Martíne. Prevention of Bone Loss in a Model of Postmenopausal Osteoporosis through Adrenomedullin Inhibition. Frontiers in physiology. vol 7. 2016-07-22. PMID:27445864. |
the endocrine influence of am on bone seems to be elicited through an indirect mechanism involving, at least, the regulation of insulin, glucose, ghrelin, and calcitonin gene-related peptide (cgrp). |
2016-07-22 |
2023-08-13 |
mouse |
| Jie Wang, Vipul Yadav, Alice L Smart, Shinichiro Tajiri, Abdul W Basi. Stability of peptide drugs in the colon. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 78. 2016-06-07. PMID:26111980. |
this study was the first to investigate the colonic stability of 17 peptide molecules (insulin, calcitonin, glucagon, secretin, somatostatin, desmopressin, oxytocin, arg-vasopressin, octreotide, ciclosporin, leuprolide, nafarelin, buserelin, histrelin, [d-ser(4)]-gonadorelin, deslorelin, and goserelin) in a model of the large intestine using mixed human faecal bacteria. |
2016-06-07 |
2023-08-13 |
human |
| Jie Wang, Vipul Yadav, Alice L Smart, Shinichiro Tajiri, Abdul W Basi. Stability of peptide drugs in the colon. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 78. 2016-06-07. PMID:26111980. |
of these, the larger peptides - insulin, calcitonin, somatostatin, glucagon and secretin - were metabolized rapidly, with complete degradation observed within 5 min. |
2016-06-07 |
2023-08-13 |
human |
| Jie Wang, Vipul Yadav, Alice L Smart, Shinichiro Tajiri, Abdul W Basi. Toward oral delivery of biopharmaceuticals: an assessment of the gastrointestinal stability of 17 peptide drugs. Molecular pharmaceutics. vol 12. issue 3. 2016-04-22. PMID:25612507. |
the aim of this study was to determine the stability of 17 disparate peptide drugs (insulin, calcitonin, glucagon, secretin, somatostatin, desmopressin, oxytocin, [arg(8)]-vasopressin, octreotide, ciclosporin, leuprolide, nafarelin, buserelin, histrelin, [d-ser](4)-gonadorelin, deslorelin, and goserelin) in gastric and small intestinal fluids from both humans and pigs, and in simulated gastric and intestinal fluids. |
2016-04-22 |
2023-08-13 |
human |
| Jie Wang, Vipul Yadav, Alice L Smart, Shinichiro Tajiri, Abdul W Basi. Toward oral delivery of biopharmaceuticals: an assessment of the gastrointestinal stability of 17 peptide drugs. Molecular pharmaceutics. vol 12. issue 3. 2016-04-22. PMID:25612507. |
in human gastric fluid, the larger peptides including somatostatin, calcitonin, secretin, glucagon, and insulin were metabolized rapidly, while the smaller peptides showed good stability. |
2016-04-22 |
2023-08-13 |
human |
| Beth L Laub. Aerosolized Medications for Gene and Peptide Therapy. Respiratory care. vol 60. issue 6. 2016-03-22. PMID:26070576. |
drugs that are highlighted include: small interfering ribonucleic acid to treat lung cancer and mycobacterium tuberculosis; vectors carrying the normal alpha-1 antitrypsin gene to treat alpha-1 antitrypsin deficiency; vectors carrying the normal cystic fibrosis transmembrane conductance regulator gene to treat cystic fibrosis; vasoactive intestinal peptide to treat asthma, pulmonary hypertension, and sarcoidosis; glutathione to treat cystic fibrosis; granulocyte-macrophage colony-stimulating factor to treat pulmonary alveolar proteinosis; calcitonin for postmenopausal osteoporosis; and insulin to treat diabetes. |
2016-03-22 |
2023-08-13 |
Not clear |
| Hailong Zhang, Xiaoyan Huang, Ya Sun, Guangyou Lu, Ke Wang, Zhigang Wang, Jianfeng Xing, Yang Ga. Improvement of pulmonary absorption of poorly absorbable macromolecules by hydroxypropyl-β-cyclodextrin grafted polyethylenimine (HP-β-CD-PEI) in rats. International journal of pharmaceutics. vol 489. issue 1-2. 2016-02-29. PMID:25959121. |
effects of hydroxypropyl-β-cyclodextrin grafted polyethylenimine (hp-β-cd-pei) including hp-β-cd-pei600, hp-β-cd-pei1800, hp-β-cd-pei10000 on the pulmonary absorption of insulin, calcitonin, 5(6)-carboxyfluorescein (cf) and fluorescein isothiocyanate dextrans (fds) with various molecular weights (fd4, fd10 and fd70) were examined by an pulmonary absorption study in rats. |
2016-02-29 |
2023-08-13 |
rat |
| Morten Asser Karsdal, Bente Juul Riis, Nozer Mehta, William Stern, Ehud Arbit, Claus Christiansen, Kim Henrikse. Lessons learned from the clinical development of oral peptides. British journal of clinical pharmacology. vol 79. issue 5. 2016-02-02. PMID:25408230. |
special interest is given to oral salmon calcitonin (ct), glucagon-like peptide-1 (glp-1), insulin, pyy-(3-36), recombinant human parathyroid hormone (rhpth(1-31)-nh2) and pth(1-34), by different technologies. |
2016-02-02 |
2023-08-13 |
human |