| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhengqi Dong, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamot. Effects of polyamidoamine (PAMAM) dendrimers on the nasal absorption of poorly absorbable drugs in rats. International journal of pharmaceutics. vol 393. issue 1-2. 2010-09-03. PMID:20417700. |
1% (w/v) g3 dendrimer also improved the nasal absorption of macromolecular compounds and drugs including fd10, fd70, insulin and calcitonin. |
2010-09-03 |
2023-08-12 |
rat |
| Zhengqi Dong, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamot. Effects of polyamidoamine (PAMAM) dendrimers on the nasal absorption of poorly absorbable drugs in rats. International journal of pharmaceutics. vol 393. issue 1-2. 2010-09-03. PMID:20417700. |
this changing might trigger the absorption enhancing effects of pamam dendrimers on the nasal absorption of fds, insulin and calcitonin, as the first step of mechanisms. |
2010-09-03 |
2023-08-12 |
rat |
| Zhengqi Dong, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamot. Effects of polyamidoamine (PAMAM) dendrimers on the nasal absorption of poorly absorbable drugs in rats. International journal of pharmaceutics. vol 393. issue 1-2. 2010-09-03. PMID:20417700. |
in conclusion, 1% (w/v) g3 dendrimer is a promising absorption enhancer for improving the nasal absorption of fds, insulin and calcitonin without any membrane damage to the nasal tissues. |
2010-09-03 |
2023-08-12 |
rat |
| Pavel Dundr, Michael Pesl, Ctibor Povýsil, Lenka Bauerová, Viktor Souku. Primary large cell neuroendocrine carcinoma of the kidney. Pathology oncology research : POR. vol 16. issue 1. 2010-06-14. PMID:19579058. |
cytokeratin cam5.2, cytokeratin 34betae12, berep 4, ema, ttf-1, cytokeratin 7, cytokeratin 20, calretinin, serotonin, somatostatin, gastrin, calcitonin, glukagon and insulin were negative. |
2010-06-14 |
2023-08-12 |
Not clear |
| John J Arnold, Michael D Fyrberg, Elias Meezan, Dennis J Pillio. Reestablishment of the nasal permeability barrier to several peptides following exposure to the absorption enhancer tetradecyl-beta-D-maltoside. Journal of pharmaceutical sciences. vol 99. issue 4. 2010-04-26. PMID:19894270. |
regular insulin, nph insulin, glargine insulin, calcitonin, and human growth hormone were administered to rats nasally with 0.125% tetradecyl-beta-d-maltoside (tdm), or at various times after tdm treatment. |
2010-04-26 |
2023-08-12 |
human |
| Lei Wei, Ping Jiang, Yin Hoe Yau, Heike Summer, Susana Geifman Shochat, Yuguang Mu, Konstantin Pervushi. Residual structure in islet amyloid polypeptide mediates its interactions with soluble insulin. Biochemistry. vol 48. issue 11. 2010-04-05. PMID:19146426. |
islet amyloid polypeptide (iapp), a 37-amino acid polypeptide hormone of the calcitonin family, is colocalized and cosecreted with insulin in secretory granules of pancreatic islet beta cells. |
2010-04-05 |
2023-08-12 |
human |
| S S Butakova, A D Nozdrache. Effect of calcium-regulating hormones and calcium channel modulators on glucose consumption by muscle and adipose tissues in vivo and in vitro. Bulletin of experimental biology and medicine. vol 148. issue 2. 2010-03-15. PMID:20027320. |
calcitonin and parathyrin did not alter glucose consumption; parathyrin did not affect, while calcitonin completely abolished the stimulating effect of insulin in vivo and in vitro. |
2010-03-15 |
2023-08-12 |
Not clear |
| S S Butakova, A D Nozdrache. Effect of calcium-regulating hormones and calcium channel modulators on glucose consumption by muscle and adipose tissues in vivo and in vitro. Bulletin of experimental biology and medicine. vol 148. issue 2. 2010-03-15. PMID:20027320. |
isoptin did not affect the stimulating effect of insulin against the background of parathyrin administration and completely blocked the inhibitory effect of calcitonin on insulin-stimulated glucose consumption by the muscle and adipose tissues in vivo and in vitro, while bay-k-8644 potentiated this effect of calcitonin in vitro. |
2010-03-15 |
2023-08-12 |
Not clear |
| S Guzel, N Gunes, H Yildiz, B Yilma. Effects of amylin on bone development and egg production in hens. Poultry science. vol 88. issue 8. 2009-09-23. PMID:19590088. |
amylin is a member of the calcitonin family of hormones cosecreted with insulin from the pancreatic beta-cells that can act as an osteoblast mitogen and as an inhibitor of bone resorption in mice and humans. |
2009-09-23 |
2023-08-12 |
mouse |
| Martin Werle, Abdallah Makhlof, Hirofumi Takeuch. Oral protein delivery: a patent review of academic and industrial approaches. Recent patents on drug delivery & formulation. vol 3. issue 2. 2009-08-17. PMID:19519570. |
oral delivery systems of proteins including insulin, glucagon like peptide, calcitonin or parathyroid hormone are highly demanded by patients suffering from chronic diseases such as diabetes or osteoporosis. |
2009-08-17 |
2023-08-12 |
Not clear |
| Noriyasu Kamei, Mariko Morishita, Hitomi Chiba, Nikhil J Kavimandan, Nicholas A Peppas, Kozo Takayam. Complexation hydrogels for intestinal delivery of interferon beta and calcitonin. Journal of controlled release : official journal of the Controlled Release Society. vol 134. issue 2. 2009-05-05. PMID:19095021. |
high loading efficiency into hydrogels was observed for insulin, calcitonin, and interferon beta. |
2009-05-05 |
2023-08-12 |
rat |
| P Gupta, A Harte, D W Sturdee, A Sharma, A H Barnett, S Kumar, P G McTerna. Effects of menopausal status on circulating calcitonin gene-related peptide and adipokines: implications for insulin resistance and cardiovascular risks. Climacteric : the journal of the International Menopause Society. vol 11. issue 5. 2008-12-16. PMID:18781480. |
effects of menopausal status on circulating calcitonin gene-related peptide and adipokines: implications for insulin resistance and cardiovascular risks. |
2008-12-16 |
2023-08-12 |
Not clear |
| Gwendoline Thiery, Elsa Anselmi, Anne Audebourg, Ekaterina Darii, Mohamed Abarbri, Benoît Terris, Jean-Claude Tabet, Ivo G Gu. Improvements of TArgeted multiplex mass spectrometry IMaging. Proteomics. vol 8. issue 18. 2008-12-02. PMID:18780398. |
sections of healthy human pancreatic tissue were imaged to visualize different specific biomarkers (synaptophysin, chromogranin, insulin, calcitonin, somatostatin) in neuroendocrine cells of langerhans islets. |
2008-12-02 |
2023-08-12 |
human |
| Yoshito Zamami, Shingo Takatori, Kousuke Yamawaki, Satoko Miyashita, Mitsunobu Mio, Yoshihisa Kitamura, Hiromu Kawasak. Acute hyperglycemia and hyperinsulinemia enhance adrenergic vasoconstriction and decrease calcitonin gene-related peptide-containing nerve-mediated vasodilation in pithed rats. Hypertension research : official journal of the Japanese Society of Hypertension. vol 31. issue 5. 2008-10-02. PMID:18712059. |
changes in vascular responses to spinal cord stimulation (scs) and intravenous bolus injections of noradrenaline, angiotensin ii, calcitonin gene-related peptide (cgrp), acetylcholine and sodium nitroprusside (snp) were studied by infusing various concentrations of glucose or insulin. |
2008-10-02 |
2023-08-12 |
rat |
| Anne Wawrezinieck, Jean-Manuel Péan, Patrick Wüthrich, Jean-Pierre Benoi. [Oral bioavailability and drug/carrier particulate systems]. Medecine sciences : M/S. vol 24. issue 6-7. 2008-09-25. PMID:18601886. |
promising preclinical results have been obtained with model drugs like paclitaxel, insulin, calcitonin, or cyclosporin. |
2008-09-25 |
2023-08-12 |
Not clear |
| Yoshito Zamami, Shingo Takatori, Yukiko Iwatani, Kousuke Yamawaki, Satoko Miyashita, Nana Yabumae, Fusako Takayama, Mitsunobu Mio, Hiromu Kawasak. [Effect of postprandial hyperglycemia and hyperinsulinemia on vascular responsiveness]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 128. issue 3. 2008-04-15. PMID:18311062. |
changes in vascular responses to spinal cord stimulation (scs) and intravenous bolus injections of noradrenaline, angiotensin ii, calcitonin gene-related peptide (cgrp), acetylcholine and sodium nitroprusside (snp) were studied by infusing various concentration of glucose or insulin. |
2008-04-15 |
2023-08-12 |
rat |
| Ahmad Amini, Elin Nilsso. Quantitative analysis of polypeptide pharmaceuticals by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Journal of pharmaceutical and biomedical analysis. vol 46. issue 3. 2008-03-06. PMID:18068324. |
an accurate method based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof-ms) has been developed for quantitative analysis of calcitonin and insulin in different commercially available pharmaceutical products. |
2008-03-06 |
2023-08-12 |
Not clear |
| Ahmad Amini, Elin Nilsso. Quantitative analysis of polypeptide pharmaceuticals by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Journal of pharmaceutical and biomedical analysis. vol 46. issue 3. 2008-03-06. PMID:18068324. |
the concentrations of calcitonin and insulin content of the analyzed pharmaceutical products were accurately determined, and less than 5% error was obtained between the present method and the manufacturer specified values. |
2008-03-06 |
2023-08-12 |
Not clear |
| Torben Clausen, Ole Baekgaard Nielse. Potassium, Na+,K+-pumps and fatigue in rat muscle. The Journal of physiology. vol 584. issue Pt 1. 2008-01-17. PMID:17673509. |
the marked loss of endurance elicited by exposure to 8 or 10 mm k(+) was alleviated or significantly reduced by stimulating the na(+),k(+)-pumps by intracellular na(+) loading, the beta(2)-agonist salbutamol, adrenaline, calcitonin gene related peptide, insulin or repeated excitation. |
2008-01-17 |
2023-08-12 |
human |
| Mayur Patel, Tejal Shah, Avani Ami. Therapeutic opportunities in colon-specific drug-delivery systems. Critical reviews in therapeutic drug carrier systems. vol 24. issue 2. 2007-11-29. PMID:17725524. |
colon targeting has also proven useful for systemic action of protein-peptide drugs such as insulin, calcitonin, and met-enkaphalin and even for other nonpeptide drugs such as cardiovascular and antiasthmatic agents. |
2007-11-29 |
2023-08-12 |
Not clear |