| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Sottrup-Jensen, T M Stepanik, T Kristensen, P B Lønblad, C M Jones, D M Wierzbicki, S Magnusson, H Domdey, R A Wetsel, A Lundwal. Common evolutionary origin of alpha 2-macroglobulin and complement components C3 and C4. Proceedings of the National Academy of Sciences of the United States of America. vol 82. issue 1. 1985-02-27. PMID:2578664. |
common evolutionary origin of alpha 2-macroglobulin and complement components c3 and c4. |
1985-02-27 |
2023-08-11 |
human |
| L Sottrup-Jensen, T M Stepanik, T Kristensen, P B Lønblad, C M Jones, D M Wierzbicki, S Magnusson, H Domdey, R A Wetsel, A Lundwal. Common evolutionary origin of alpha 2-macroglobulin and complement components C3 and C4. Proceedings of the National Academy of Sciences of the United States of America. vol 82. issue 1. 1985-02-27. PMID:2578664. |
it is proposed that alpha 2m, c3 and c4, which all contain a unique activatable beta-cysteinyl-gamma-glutamyl thiol ester, have a common evolutionary origin and are homologous proteins. |
1985-02-27 |
2023-08-11 |
human |
| L Sottrup-Jensen, T M Stepanik, T Kristensen, P B Lønblad, C M Jones, D M Wierzbicki, S Magnusson, H Domdey, R A Wetsel, A Lundwal. Common evolutionary origin of alpha 2-macroglobulin and complement components C3 and C4. Proceedings of the National Academy of Sciences of the United States of America. vol 82. issue 1. 1985-02-27. PMID:2578664. |
the quartets of basic residues in pro-c3 and pro-c4, at which cleavage takes place to produce the mature subunits of these proteins, and most of the residues forming the anaphylatoxin peptides of c3 and c4 (c3a and c4a) are absent in alpha 2m. |
1985-02-27 |
2023-08-11 |
human |
| L Sottrup-Jensen, T M Stepanik, T Kristensen, P B Lønblad, C M Jones, D M Wierzbicki, S Magnusson, H Domdey, R A Wetsel, A Lundwal. Common evolutionary origin of alpha 2-macroglobulin and complement components C3 and C4. Proceedings of the National Academy of Sciences of the United States of America. vol 82. issue 1. 1985-02-27. PMID:2578664. |
in addition, c3 and c4 contain large portions, which extend beyond the cooh terminus of alpha 2m. |
1985-02-27 |
2023-08-11 |
human |
| S Nakashima, H Kamikaw. Accelerated expansion of antibody heterogeneity by complete Freund's adjuvant during the response to bacterial alpha-amylase. Immunology. vol 53. issue 4. 1985-01-17. PMID:6334022. |
regardless of the strain difference in responsiveness to b alpha a between c3h/he (c3) and c57b1/6 (b6) mice, the enhancing effect of cfa was characterized by an accelerated expansion of ief spectra and by the intensified stain of focused antibody, compared with the response of mice immunized with the same antigen dose in ifa. |
1985-01-17 |
2023-08-12 |
mouse |
| R A Wetsel, A Lundwall, F Davidson, T Gibson, B F Tack, G H Fe. Structure of murine complement component C3. II. Nucleotide sequence of cloned complementary DNA coding for the alpha chain. The Journal of biological chemistry. vol 259. issue 22. 1984-12-27. PMID:6094532. |
from the inserts of two recombinant plasmids isolated from a murine liver cdna library, the nucleotide sequence coding for the c3 alpha chain was obtained and the corresponding amino acid sequence was derived. |
1984-12-27 |
2023-08-12 |
human |
| R A Wetsel, A Lundwall, F Davidson, T Gibson, B F Tack, G H Fe. Structure of murine complement component C3. II. Nucleotide sequence of cloned complementary DNA coding for the alpha chain. The Journal of biological chemistry. vol 259. issue 22. 1984-12-27. PMID:6094532. |
in addition, the positions for two putative factor i cleavage sites were predicted from a comparison with the cleavage sites in the human c3 alpha chain. |
1984-12-27 |
2023-08-12 |
human |
| R A Wetsel, A Lundwall, F Davidson, T Gibson, B F Tack, G H Fe. Structure of murine complement component C3. II. Nucleotide sequence of cloned complementary DNA coding for the alpha chain. The Journal of biological chemistry. vol 259. issue 22. 1984-12-27. PMID:6094532. |
the c3 alpha chain contains 24 cysteine residues, 10 of these clustered in the c-terminal 175 amino acids of the alpha chain. |
1984-12-27 |
2023-08-12 |
human |
| G H Fey, A Lundwall, R A Wetsel, B F Tack, M H de Bruijn, H Domde. Nucleotide sequence of complementary DNA and derived amino acid sequence of murine complement protein C3. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 306. issue 1129. 1984-11-28. PMID:6208565. |
the equivalent position of the known factor i cleavage sites in human c3 alpha could be located in the murine c3 alpha chain and the size and sequence of the resulting peptide were deduced. |
1984-11-28 |
2023-08-12 |
human |
| G H Fey, A Lundwall, R A Wetsel, B F Tack, M H de Bruijn, H Domde. Nucleotide sequence of complementary DNA and derived amino acid sequence of murine complement protein C3. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 306. issue 1129. 1984-11-28. PMID:6208565. |
a comparison of the amino acid sequences of murine c3 and human alpha 2-macroglobulin is given. |
1984-11-28 |
2023-08-12 |
human |
| S Nakashima, H Kamikaw. Sequential expansion of antibody heterogeneity during the response to bacterial alpha-amylase. Journal of biochemistry. vol 96. issue 1. 1984-11-28. PMID:6333420. |
by analyzing antibody heterogeneity during the primary immune response to bacterial a-amylase (b alpha a) in high-responder f1 hybrid mice between c57bl/6 (b6) and c3h/he (c3) mice with the use of isoelectric focusing (ief), it was shown that the maturation of the primary igg antibody response consisted of at least two stages. |
1984-11-28 |
2023-08-12 |
mouse |
| M David, A Lobéra, E Legran. [Changes in the serum protein profile during radiotherapy of the upper respiratory and digestive tracts]. Annales de biologie clinique. vol 42. issue 4. 1984-11-27. PMID:6497072. |
the weekly monitoring of the protein profile showed a gradual and significant decrease in the levels of nutritional proteins (prealbumin, retinol binding protein, transferrin) and immunoglobulins (igm, iga) and a small variation in the levels of inflammatory proteins (haptoglobin, orosomucoid, c3 complement fraction, alpha 1-antitrypsin). |
1984-11-27 |
2023-08-12 |
Not clear |
| R E Chambers, J T Whicher, D G Bulloc. External quality assessment of immunoassays for specific proteins in serum; 18 months' experience in the United Kingdom. Annals of clinical biochemistry. vol 21 ( Pt 4). 1984-11-20. PMID:6333201. |
five surveys of immunoglobulin a, g and m assay have been carried out in 200 uk laboratories; assays of complement components c3 and c4 and alpha 1-antitrypsin (alpha 1-at) by 70 laboratories were also included in the fourth and fifth surveys. |
1984-11-20 |
2023-08-12 |
human |
| R E Chambers, J T Whicher, D G Bulloc. External quality assessment of immunoassays for specific proteins in serum; 18 months' experience in the United Kingdom. Annals of clinical biochemistry. vol 21 ( Pt 4). 1984-11-20. PMID:6333201. |
inter-laboratory precision was better for c4 than for c3 and alpha 1-at, which indicates the importance of calibrant differences for the latter two; there were too few participants to allow reliable conclusions about methods to be drawn. |
1984-11-20 |
2023-08-12 |
human |
| G K Endresen, O J Mellby. Studies on the binding of complement factor C3 to the surface of human blood platelets. Haemostasis. vol 14. issue 3. 1984-10-19. PMID:6381253. |
employing immunofluorescent staining methods, platelets from several adult patients with chronic idiopathic thrombocytopenic purpura, with systemic lupus erythematosus, and with classical rheumatoid arthritis stained positively with antisera to c3(beta 1c) and c3dg(alpha 2d). |
1984-10-19 |
2023-08-12 |
human |
| M Matsushita, U Sankawa, T Okuda, H Okada, T Sasak. A cleavage product of mouse C3 adsorbable to (1----3)-beta-D-glucan from Alcaligenes faecalis var. myxogenes IFO 13140. The Japanese journal of experimental medicine. vol 53. issue 5. 1984-10-12. PMID:6206261. |
in contrast to c3, c3x had an intact beta chain (70,000 daltons) and instead of an alpha chain, two peptide chains (40,000 and 30,000 daltons) linked by disulfide bonds. |
1984-10-12 |
2023-08-12 |
mouse |
| R H Derksen, H J Schuurman, F H Meyling, A Struyvenberg, L Kate. The efficacy of plasma exchange in the removal of plasma components. The Journal of laboratory and clinical medicine. vol 104. issue 3. 1984-09-26. PMID:6206173. |
the efficacy of plasma exchange in the removal of immunoglobulins (igg, igm, iga), complement components (c1q, c4, c3), alpha 1-antitrypsin, alpha 2-macroglobulin, and transferrin was studied by analysis of pre- and postexchange serum samples and the plasma removed both in a healthy volunteer and in five patients undergoing therapeutic plasma exchange. |
1984-09-26 |
2023-08-12 |
human |
| R H Derksen, H J Schuurman, F H Meyling, A Struyvenberg, L Kate. The efficacy of plasma exchange in the removal of plasma components. The Journal of laboratory and clinical medicine. vol 104. issue 3. 1984-09-26. PMID:6206173. |
this was particularly the case for c4, c3, alpha 1-antitrypsin, and alpha 2-macroglobulin and may be explained by influx from the extra- to the intravascular compartment during the procedure. |
1984-09-26 |
2023-08-12 |
human |
| L R Lamontagne, J Gauldie, A D Befus, K P McAdam, M L Baltz, M B Pepy. The acute phase response in parasite infection. Nippostrongylus brasiliensis in the mouse. Immunology. vol 52. issue 4. 1984-09-19. PMID:6204934. |
we examined serum changes of four acute phase reactants: alpha 1-proteinase inhibition (alpha 1pi); complement c3; serum amyloid a protein (saa); and serum amyloid p component (sap), in mice undergoing a primary infection with nippostrongylus brasiliensis. |
1984-09-19 |
2023-08-12 |
mouse |
| L R Lamontagne, J Gauldie, A D Befus, K P McAdam, M L Baltz, M B Pepy. The acute phase response in parasite infection. Nippostrongylus brasiliensis in the mouse. Immunology. vol 52. issue 4. 1984-09-19. PMID:6204934. |
alpha 1pi and c3 serum levels were not altered. |
1984-09-19 |
2023-08-12 |
mouse |