| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M E Bake. Amino acid sequence homology between the C3 chain of rat prostatic steroid binding protein and human alpha 2-macroglobulin. Biochemical and biophysical research communications. vol 122. issue 2. 1984-09-12. PMID:6205654. |
amino acid sequence homology between the c3 chain of rat prostatic steroid binding protein and human alpha 2-macroglobulin. |
1984-09-12 |
2023-08-12 |
human |
| M E Bake. Amino acid sequence homology between the C3 chain of rat prostatic steroid binding protein and human alpha 2-macroglobulin. Biochemical and biophysical research communications. vol 122. issue 2. 1984-09-12. PMID:6205654. |
using a computer program designed to detect evolutionary relationships between proteins, i find that exon 2 of the c3 chain of rat prostatic steroid binding protein has amino acid sequence homology with residues 1058-1119 of the protease inhibitor alpha 2-macroglobulin. |
1984-09-12 |
2023-08-12 |
human |
| A A McCracken, M Emmett, A J Crowle, J L Brow. Studies on the secretion of serum proteins from rat hepatoma cells. Hepatology (Baltimore, Md.). vol 4. issue 4. 1984-08-30. PMID:6745862. |
ten of these: albumin, alpha 1-antitrypsin, alpha 1-lipoprotein, alpha 1-macroglobulin, alpha 1-antichymotrypsin, gc-globulin (transcalciferin), fibronectin, hemopexin, transferrin and the c3 component of complement have been identified. |
1984-08-30 |
2023-08-12 |
rat |
| L Sottrup-Jensen, T M Stepanik, T Kristensen, D M Wierzbicki, C M Jones, P B Lønblad, S Magnusson, T E Peterse. Primary structure of human alpha 2-macroglobulin. V. The complete structure. The Journal of biological chemistry. vol 259. issue 13. 1984-08-20. PMID:6203908. |
a comparison of stretches of sequences from alpha 2-macroglobulin with partial sequence data for complement components c3 and c4 indicates that these proteins are evolutionary related. |
1984-08-20 |
2023-08-12 |
human |
| L Sottrup-Jensen, T M Stepanik, T Kristensen, D M Wierzbicki, C M Jones, P B Lønblad, S Magnusson, T E Peterse. Primary structure of human alpha 2-macroglobulin. V. The complete structure. The Journal of biological chemistry. vol 259. issue 13. 1984-08-20. PMID:6203908. |
the properties of alpha 2-macroglobulin are discussed within the context of proteolytically regulated systems with particular reference to the complement components c3 and c4. |
1984-08-20 |
2023-08-12 |
human |
| S Suter, D Berger, J P Despont, F Waldvoge. Low levels of functional of alpha 1-proteinase inhibitor in the promotion of C3-cleavage by granulocyte-neutral proteases in pleural empyema. The Journal of infectious diseases. vol 149. issue 6. 1984-08-03. PMID:6203992. |
in the present study it was shown that in 17 infected pleural effusions, high proteolytic activity on 125i-labeled c3 (16.3% +/- 4.4%) correlated with low functional levels of alpha 1-proteinase inhibitor (alpha 1-pi), as determined by trypsin-inhibitory capacity (56.2 +/- 20.1 iu/ml; rs = -0.97, p less than .001), whereas in 18 sterile pleural effusions there was no such correlation (125i-labeled c3 cleavage, 2.2% +/- .2%; trypsin-inhibitory capacity, 192.6 +/- 26.7 iu/ml). |
1984-08-03 |
2023-08-12 |
Not clear |
| E Bleumink, H A Klokk. Protease-inhibitor deficiencies in a patient with Weber-Christian panniculitis. Archives of dermatology. vol 120. issue 7. 1984-07-20. PMID:6203490. |
studies of serum complement and kallikrein levels and of the fibrinolysis-clotting system showed a decrease in the levels of c3, c4, and total hemolytic complement activity and deficiencies (less than 20% of the normal values) of alpha 1-antitrypsin (alpha 1-at) and antichymotrypsin activity. |
1984-07-20 |
2023-08-12 |
Not clear |
| Z Parve. Laser nephelometry: development, clinical application, and future prospects. Medical instrumentation. vol 18. issue 2. 1984-07-11. PMID:6610093. |
plasma protein alpha 1-antitrypsin (alpha 1-at) and the serum complement component c3 have been quantitated by a laser nephelometric technique. |
1984-07-11 |
2023-08-12 |
Not clear |
| Z Parve. Laser nephelometry: development, clinical application, and future prospects. Medical instrumentation. vol 18. issue 2. 1984-07-11. PMID:6610093. |
the correlation coefficient between the laser nephelometric and the rid methods was r = 0.87 for alpha 1-at, and r = 0.80 for c3 in normal serum. |
1984-07-11 |
2023-08-12 |
Not clear |
| Z Parve. Laser nephelometry: development, clinical application, and future prospects. Medical instrumentation. vol 18. issue 2. 1984-07-11. PMID:6610093. |
the alpha 1-at concentration determined by the laser method ranged from 161 to 393 mg/dl in normal plasma, whereas the serum c3 concentration in normal serum was found to be 76.5 +/- 21.9 mg/dl. |
1984-07-11 |
2023-08-12 |
Not clear |
| H F Lodish, N Kon. Glucose removal from N-linked oligosaccharides is required for efficient maturation of certain secretory glycoproteins from the rough endoplasmic reticulum to the Golgi complex. The Journal of cell biology. vol 98. issue 5. 1984-06-25. PMID:6233287. |
in a pulse-chase experiment, 1- deoxynojirimycin greatly reduced the rate of secretion of alpha 1-antitrypsin and alpha 1-antichymotrypsin by human hepatoma hepg2 cells, but had marginal effects on secretion of the glycoproteins c3 and transferrin, or of albumin. |
1984-06-25 |
2023-08-12 |
human |
| K G Sjöblom, T Saxne, H Pettersson, F A Wollhei. Factors related to the progression of joint destruction in rheumatoid arthritis. Scandinavian journal of rheumatology. vol 13. issue 1. 1984-06-11. PMID:6719058. |
in 103 (m = 25, f = 78) of 150 consecutive ra patients, values of the following variables were obtained at the start and end of a 2-year follow-up period: radiographic destruction score of hands and feet according to larsen (larsen index), ritchie index, b-hemoglobin, esr and plasma proteins (alpha 1-antitrypsin, ceruloplasmin, crp, fibrinogen, haptoglobin, orosomucoid, iga, igg, igm, c3 and c4). |
1984-06-11 |
2023-08-12 |
Not clear |
| R B Sim, E Si. Autolytic fragmentation of complement components C3 and C4 and its relationship to covalent binding activity. Annals of the New York Academy of Sciences. vol 421. 1984-06-06. PMID:6202197. |
the ease with which autolysis can be induced and observed in c3, c4, and alpha 2 m has provided a valuable method for detecting the active forms of these proteins in circumstances where other assays are impracticable, as, for example, in the examination of the uptake of active c3 by lymphocytes. |
1984-06-06 |
2023-08-12 |
mouse |
| R B Sim, E Si. Autolytic fragmentation of complement components C3 and C4 and its relationship to covalent binding activity. Annals of the New York Academy of Sciences. vol 421. 1984-06-06. PMID:6202197. |
gross structural comparisons made among c3, c4, and alpha 2 m on the basis of alignment of the autolytic cleavage sites and the protease-activation sites in these proteins were useful in predicting how the alpha-, beta-, and gamma-chains of c4, or the alpha- and beta-chains of c3, were aligned in the single polypeptide chain pro-forms of these proteins. |
1984-06-06 |
2023-08-12 |
mouse |
| R B Sim, E Si. Autolytic fragmentation of complement components C3 and C4 and its relationship to covalent binding activity. Annals of the New York Academy of Sciences. vol 421. 1984-06-06. PMID:6202197. |
although autolytic cleavage has been described only for c3, c4, alpha 2 m, and slp, it is likely that other proteins will be found that exhibit this phenomenon. |
1984-06-06 |
2023-08-12 |
mouse |
| Y Takata, N Tamura, T Fujit. Interaction of C3 with antigen-antibody complexes in the process of solubilization of immune precipitates. Journal of immunology (Baltimore, Md. : 1950). vol 132. issue 5. 1984-06-01. PMID:6232320. |
furthermore, we demonstrated that generation of c3b in the presence of 3h-tyrosine resulted in covalent binding of the tyrosine specifically to the c3 alpha' chain, indicating that the inhibition of solubilization may be due to the competition between tyrosine and immune complexes for the covalent binding of c3. |
1984-06-01 |
2023-08-12 |
cattle |
| L Sann, F Bienvenu, M Maurice, C Lahet, P Baltassa. [Humoral factors of immunity in maternal milk. Comparison of their levels in the breast milk of mothers with premature and at-term delivery]. Pediatrie. vol 38. issue 8. 1984-05-30. PMID:6609344. |
eight proteins (immunoglobulin a, g, m, c3 and c4 fractions of complement, alpha 1-glycoprotein, lactoferrin and alpha 1- antitrypsin) were measured by immuno-diffusion or laser nephelometry in 50 milk samples. |
1984-05-30 |
2023-08-12 |
Not clear |
| E J Hamilton, W Tostowaryk, J A Caron, A Godard, B W Griffith. Preparation and calibration of a reference preparation for human serum proteins. Clinical biochemistry. vol 17. issue 1. 1984-05-23. PMID:6705186. |
the u.s. national rphsp was used to cross-calibrate our reference serum by single radial immunodiffusion for the analytes alpha 1-acid glycoprotein, alpha 1-antitrypsin, alpha 2-macroglobulin, ceruloplasmin, c3, c4, haptoglobin, transferrin, iga, igg, igm and by laurell "rocket" assay for albumin. |
1984-05-23 |
2023-08-12 |
human |
| A Lasson, K Ohlsso. On the potential role of trypsin and trypsin inhibitors in acute pancreatitis. Advances in experimental medicine and biology. vol 167. 1984-05-21. PMID:6201050. |
the protective role of alpha 2-macroglobulin, alpha 1-antitrypsin and aprotinin against trypsin-induced effects on c3 and kininogen was studied in a human in vitro model. |
1984-05-21 |
2023-08-12 |
human |
| A Lasson, K Ohlsso. On the potential role of trypsin and trypsin inhibitors in acute pancreatitis. Advances in experimental medicine and biology. vol 167. 1984-05-21. PMID:6201050. |
when alpha 2-macroglobulin was 70% saturated, there was a prompt cleavage of both c3 and kininogen, in spite of 80% free and active alpha 1-antitrypsin. |
1984-05-21 |
2023-08-12 |
human |