| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Oda, K Miki, S Hirose, N Takami, Y Misumi, Y Ikehar. Immunoblotting analysis of plasma protein processing in the secretory pathway of rat liver: identification of proteolytic conversion sites of complement pro-C3 and prohaptoglobin. Journal of biochemistry. vol 100. issue 6. 1987-05-26. PMID:3553170. |
each subcellular fraction was directly subjected to sds-polyacrylamide gel electrophoresis and analyzed by immunoblotting with antibodies against alpha 1-protease inhibitor, haptoglobin, and the third component of complement (c3) in combination with 125i-protein a or 125i-rabbit anti-(goat igg)-igg. |
1987-05-26 |
2023-08-11 |
rat |
| N L Harrison, M D Majewska, J W Harrington, J L Barke. Structure-activity relationships for steroid interaction with the gamma-aminobutyric acidA receptor complex. The Journal of pharmacology and experimental therapeutics. vol 241. issue 1. 1987-05-22. PMID:3033209. |
the essential features of the active structures are a 5 alpha or 5 beta-reduced pregnane skeleton with a hydroxyl at c3 in the alpha-position and a ketone group at c20. |
1987-05-22 |
2023-08-11 |
rat |
| K Ohlsso. Influence of the human pancreatic secretory trypsin inhibitor on trypsin-induced C3 and kininogen cleavage: an in vitro study. Scandinavian journal of gastroenterology. Supplement. vol 126. 1987-05-08. PMID:2436281. |
when alpha 2-macroglobulin reached about 70% saturation, there was a prompt cleavage of most of the c3 and kininogen in spite of the presence of 90% free alpha 1-proteinase inhibitor. |
1987-05-08 |
2023-08-11 |
human |
| K Miki, S Ogata, Y Misumi, Y Ikehar. Carbohydrate structures of the third component of rat complement. Presence of both high-mannose and complex type oligosaccharide chains. The Biochemical journal. vol 240. issue 3. 1987-04-20. PMID:3827861. |
when the cells were incubated with [3h]mannose, [3h]galactose or [3h]glucosamine, these radioactive precursors were incorporated only into the alpha subunit of c3, demonstrating that only the alpha subunit contains oligosaccharide chains. |
1987-04-20 |
2023-08-11 |
human |
| K Miki, S Ogata, Y Misumi, Y Ikehar. Carbohydrate structures of the third component of rat complement. Presence of both high-mannose and complex type oligosaccharide chains. The Biochemical journal. vol 240. issue 3. 1987-04-20. PMID:3827861. |
taken together with the carbohydrate composition of rat serum c3, the results suggest that rat c3 has one high-mannose type oligosaccharide chain and two complex type chains in the alpha subunit, which is different from the proposal for human c3. |
1987-04-20 |
2023-08-11 |
human |
| K L Behar, O A Petroff, J W Prichard, J R Alger, R G Shulma. Detection of metabolites in rabbit brain by 13C NMR spectroscopy following administration of [1-13C]glucose. Magnetic resonance in medicine. vol 3. issue 6. 1987-04-02. PMID:2881185. |
within 15 min of infusion, the alpha and beta anomers of glucose were detected and, shortly thereafter, the carbon atoms at positions c4, c3, and c2 of glutamate and(or) glutamine. |
1987-04-02 |
2023-08-11 |
rabbit |
| J Romette, J di Costanzo-Dufetel, M Charre. [Inflammatory syndrome and changes in plasma proteins]. Pathologie-biologie. vol 34. issue 9. 1987-03-10. PMID:2433674. |
the complement components c3 and c4, transferrin and alpha 2-macroglobulin can also be generated by the macrophages. |
1987-03-10 |
2023-08-11 |
Not clear |
| L Dominioni, R Dionigi, M Zanello, R Monico, R Cremaschi, R Dionigi, A Ballabio, M Massa, M Comelli, P Dal R. Sepsis score and acute-phase protein response as predictors of outcome in septic surgical patients. Archives of surgery (Chicago, Ill. : 1960). vol 122. issue 2. 1987-02-25. PMID:3492985. |
in a series of 135 patients with severe surgical infections, we determined the sepsis score and the plasma level of the acute-phase proteins alpha-1-acid glycoprotein, alpha 1-antitrypsin, complement factor b, and c3. |
1987-02-25 |
2023-08-11 |
Not clear |
| S A Khan, J M Sekulski, B W Erickso. Peptide models of protein metastable binding sites: competitive kinetics of isomerization and hydrolysis. Biochemistry. vol 25. issue 18. 1986-12-15. PMID:3768339. |
alpha 2-macroglobulin and the complement components c3 and c4 each contain a metastable binding site that is essential for covalent attachment. |
1986-12-15 |
2023-08-11 |
Not clear |
| M S Rutherford, C S Baehler, A Richardso. Genetic expression of complement factors and alpha 1-acid glycoprotein by liver tissue during senescence. Mechanisms of ageing and development. vol 35. issue 3. 1986-12-11. PMID:3640187. |
the levels of complement factors c3 and c4, complement protein factor b, and alpha 1-acid glycoprotein were determined by dot blot hybridization using cdna probes. |
1986-12-11 |
2023-08-11 |
rat |
| M S Rutherford, C S Baehler, A Richardso. Genetic expression of complement factors and alpha 1-acid glycoprotein by liver tissue during senescence. Mechanisms of ageing and development. vol 35. issue 3. 1986-12-11. PMID:3640187. |
there was no evidence for age-related changes in the post-transcriptional processing or degradation of the mrna species coding for complement factors c3 and c4, complement protein factor b, and alpha 1-acid glycoprotein. |
1986-12-11 |
2023-08-11 |
rat |
| D H Perlmutter, C A Dinarello, P I Punsal, H R Colte. Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression. The Journal of clinical investigation. vol 78. issue 5. 1986-11-26. PMID:2429991. |
in picomolar concentrations, tnf mediated reversible, dose- and time-dependent increases in biosynthesis of complement proteins factor b and c3, alpha 1 antichymotrypsin, and decreases in biosynthesis of albumin and transferrin in human hepatoma cell lines (hep g2, hep 3b). |
1986-11-26 |
2023-08-11 |
human |
| G M Lipkind, A S Shashkov, Iu A Knirel', N K Kochetko. [Experimental and theoretical conformation analysis of the O-antigenic polysaccharide from Pseudomonas cepacia strain 3181. I. Disaccharide links]. Bioorganicheskaia khimiia. vol 12. issue 6. 1986-11-25. PMID:2430575. |
nuclear overhauser effects, with preirradiation of glycoside bond anomeric protons, coupling constants 3j c3, h1' and 3j c1', h4 and linkage optical rotations a were measured for l-rha beta 1-3-l-rha alpha 1-ome and l-rha alpha 1-3-l-rha alpha 1-ome which are the models of the disaccharide units of the pseudomonas cepacia polysaccharide. |
1986-11-25 |
2023-08-11 |
Not clear |
| P H Kay, R L Dawkins, A T Bowling, D Bernoc. Electrophoretic polymorphism and molecular structure of equine C3. Animal genetics. vol 17. issue 3. 1986-11-18. PMID:3767078. |
sds page analysis of equine c3/anti c3 complexes revealed that the submolecular structure comprised an alpha chain and beta chain of molecular weights approximately 118,000 and 63,000 daltons respectively. |
1986-11-18 |
2023-08-11 |
Not clear |
| T L Moore, R W Dorne. Separation and characterization of complement-fixing immune complexes in juvenile rheumatoid arthritis patients. Rheumatology international. vol 6. issue 2. 1986-11-07. PMID:3532285. |
sera from 14 jra patients (four seropositive for 19s igm rf and 10 seronegative, but nine having hidden 19s igm rf) were analyzed by the anti-human clq (alpha hclq) and anti-human c3 (alpha hc3) columns. |
1986-11-07 |
2023-08-11 |
Not clear |
| J P Lebreton, M Daveau, M Hiron, M Fontaine, D Biou, D Gilbert, C Guguen-Guillouz. Long-term biosynthesis of complement component C3 and alpha-1 acid glycoprotein by adult rat hepatocytes in a co-culture system with an epithelial liver cell-type. The Biochemical journal. vol 235. issue 2. 1986-09-17. PMID:3741399. |
we used a system of co-culture of adult rat hepatocytes with another epithelial cell type from rat liver to study the synthesis of two acute-phase reactants, alpha-1 acid glycoprotein (alpha 1agp) and the third component of complement (c3), and we have obtained long-term secretion of these two proteins. |
1986-09-17 |
2023-08-11 |
rat |
| J P Lebreton, M Daveau, M Hiron, M Fontaine, D Biou, D Gilbert, C Guguen-Guillouz. Long-term biosynthesis of complement component C3 and alpha-1 acid glycoprotein by adult rat hepatocytes in a co-culture system with an epithelial liver cell-type. The Biochemical journal. vol 235. issue 2. 1986-09-17. PMID:3741399. |
after a period of adaptation corresponding to the first 2-4 days of the co-culture, hepatocytes secreted c3 and alpha 1agp for at least 2 weeks at a mean level higher than that observed in the first days of a pure culture of hepatocytes. |
1986-09-17 |
2023-08-11 |
rat |
| J P Lebreton, M Daveau, M Hiron, M Fontaine, D Biou, D Gilbert, C Guguen-Guillouz. Long-term biosynthesis of complement component C3 and alpha-1 acid glycoprotein by adult rat hepatocytes in a co-culture system with an epithelial liver cell-type. The Biochemical journal. vol 235. issue 2. 1986-09-17. PMID:3741399. |
when pulse-chase analysis was performed on day 6 of co-culture, kinetics of synthesis of alpha 1agp and c3 were the same as those observed on day 1 of a conventional culture of pure hepatocytes. |
1986-09-17 |
2023-08-11 |
rat |
| J P Lebreton, M Daveau, M Hiron, M Fontaine, D Biou, D Gilbert, C Guguen-Guillouz. Long-term biosynthesis of complement component C3 and alpha-1 acid glycoprotein by adult rat hepatocytes in a co-culture system with an epithelial liver cell-type. The Biochemical journal. vol 235. issue 2. 1986-09-17. PMID:3741399. |
therefore, the system of adult hepatocytes co-cultured with this liver epithelial cell provides a physiological system in vitro which permits long-term synthesis of the two acute-phase reactants c3 and alpha 1agp. |
1986-09-17 |
2023-08-11 |
rat |
| P J Lachmann, L Strangeways, A Vyakarnam, G Eva. Raising antibodies by coupling peptides to PPD and immunizing BCG-sensitized animals. Ciba Foundation symposium. vol 119. 1986-09-16. PMID:3015516. |
data on immunization with the leucotactic nonapeptide of the alpha chain of the complement component c3 and with some oncogene-related peptides have been obtained. |
1986-09-16 |
2023-08-11 |
Not clear |