| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tapan Behl, Tarapati Rana, Aayush Sehgal, Neelam Sharma, Ali Albarrati, Mohammed Albratty, Hafiz A Makeen, Asim Najmi, Raman Verma, Simona Gabriela Bunga. Explorng the multifocal role of phytoconstituents as antidepressants. Progress in neuro-psychopharmacology & biological psychiatry. 2022-12-12. PMID:36509251. |
most of the phytoconstituents were found to mediate their antidepressant effect through the upregulation of brain-derived neurotrophic factor (bdnf), serotonin, noradrenaline, and dopamine. |
2022-12-12 |
2023-08-14 |
Not clear |
| Yan Zhuang, Runying Zeng, Xiao Liu, Longhe Yang, Zhuhua Cha. Neoagaro-Oligosaccharides Ameliorate Chronic Restraint Stress-Induced Depression by Increasing 5-HT and BDNF in the Brain and Remodeling the Gut Microbiota of Mice. Marine drugs. vol 20. issue 11. 2022-11-24. PMID:36422003. |
neoagaro-oligosaccharides ameliorate chronic restraint stress-induced depression by increasing 5-ht and bdnf in the brain and remodeling the gut microbiota of mice. |
2022-11-24 |
2023-08-14 |
mouse |
| Yan Zhuang, Runying Zeng, Xiao Liu, Longhe Yang, Zhuhua Cha. Neoagaro-Oligosaccharides Ameliorate Chronic Restraint Stress-Induced Depression by Increasing 5-HT and BDNF in the Brain and Remodeling the Gut Microbiota of Mice. Marine drugs. vol 20. issue 11. 2022-11-24. PMID:36422003. |
anxiety and depression behaviors were assessed by open field tests (oft) and forced swimming tests (fst), while interleukin 18 (il-18), 5-hydroxytryptamine (5-ht) and brain-derived neurotrophic factor (bdnf) were the molecular biomarkers of depression. |
2022-11-24 |
2023-08-14 |
mouse |
| Yan Zhuang, Runying Zeng, Xiao Liu, Longhe Yang, Zhuhua Cha. Neoagaro-Oligosaccharides Ameliorate Chronic Restraint Stress-Induced Depression by Increasing 5-HT and BDNF in the Brain and Remodeling the Gut Microbiota of Mice. Marine drugs. vol 20. issue 11. 2022-11-24. PMID:36422003. |
nao treatment decreased the levels of il-18 in the serum and increased the levels of 5-ht in the serum and whole brain and of bdnf in the whole brain. |
2022-11-24 |
2023-08-14 |
mouse |
| Yan Zhuang, Runying Zeng, Xiao Liu, Longhe Yang, Zhuhua Cha. Neoagaro-Oligosaccharides Ameliorate Chronic Restraint Stress-Induced Depression by Increasing 5-HT and BDNF in the Brain and Remodeling the Gut Microbiota of Mice. Marine drugs. vol 20. issue 11. 2022-11-24. PMID:36422003. |
in a word, naos effectively reversed the crs-induced mice model of depression, which depended on the changes in the gut microbiota and scfas, as well as its modulation of 5-ht and bdnf. |
2022-11-24 |
2023-08-14 |
mouse |
| Salar Vaseghi, Ali Mostafavijabbari, Mohammad-Sadegh Alizadeh, Reza Ghaffarzadegan, Gita Kholghi, Mohammad-Reza Zarrindas. Intricate role of sleep deprivation in modulating depression: focusing on BDNF, VEGF, serotonin, cortisol, and TNF-α. Metabolic brain disease. 2022-11-18. PMID:36399239. |
intricate role of sleep deprivation in modulating depression: focusing on bdnf, vegf, serotonin, cortisol, and tnf-α. |
2022-11-18 |
2023-08-14 |
Not clear |
| Salar Vaseghi, Ali Mostafavijabbari, Mohammad-Sadegh Alizadeh, Reza Ghaffarzadegan, Gita Kholghi, Mohammad-Reza Zarrindas. Intricate role of sleep deprivation in modulating depression: focusing on BDNF, VEGF, serotonin, cortisol, and TNF-α. Metabolic brain disease. 2022-11-18. PMID:36399239. |
regarding this issue, we chose some important factors involved in the effects of sd on cognitive functions and mood including brain-derived neurotrophic factor (bdnf), vascular endothelial growth factor (vegf), serotonin, cortisol, and tumor necrosis factor-alpha (tnf-α). |
2022-11-18 |
2023-08-14 |
Not clear |
| Salar Vaseghi, Ali Mostafavijabbari, Mohammad-Sadegh Alizadeh, Reza Ghaffarzadegan, Gita Kholghi, Mohammad-Reza Zarrindas. Intricate role of sleep deprivation in modulating depression: focusing on BDNF, VEGF, serotonin, cortisol, and TNF-α. Metabolic brain disease. 2022-11-18. PMID:36399239. |
it was concluded that sd has a wide-range of inconsistent effects on bdnf, vegf, serotonin, and cortisol levels. |
2022-11-18 |
2023-08-14 |
Not clear |
| Andrey Sequeira-Cordero, Juan C Brene. Time course of plasticity-related alterations following the first exposure to amphetamine in juvenile rats. Pharmacology, biochemistry, and behavior. 2022-11-14. PMID:36375621. |
high amph responders characterized by overexpressing bdnf, creb, p250gap, and crf in nac and by showing lower levels of dopamine and serotonin metabolites and turnovers in both regions. |
2022-11-14 |
2023-08-14 |
rat |
| Benneth Ben-Azu, Christian I Uruaka, Abayomi M Ajayi, Thiophilus Aghogho Jarikre, Kingsley E Nwangwa, Kingsley C Chilaka, Bienose S Chijioke, Marymagdalene G Omonyeme, Chineye B Ozege, Emmanuella C Ofili, Ebidenara B Warekoromor, Nwanneka L Edigbue, Ufoma V Esiekpe, Dabrechi E Akaenyi, Gladys O Ag. Reversal and Preventive Pleiotropic Mechanisms Involved in the Antipsychotic-Like Effect of Taurine, an Essential β-Amino Acid in Ketamine-Induced Experimental Schizophrenia in Mice. Neurochemical research. 2022-11-09. PMID:36350433. |
neurochemical (dopamine, 5-hydroxytryptamine, glutamic acid decarboxylase, (gad)), brain derived-neurotrophic factor (bdnf) and pro-inflammatory cytokines [tumor necrosis factor-alpha, (tnf-α), interleukin-6, (il-6)] were assayed in the striatum, prefrontal-cortex and hippocampal area. |
2022-11-09 |
2023-08-14 |
mouse |
| Benneth Ben-Azu, Christian I Uruaka, Abayomi M Ajayi, Thiophilus Aghogho Jarikre, Kingsley E Nwangwa, Kingsley C Chilaka, Bienose S Chijioke, Marymagdalene G Omonyeme, Chineye B Ozege, Emmanuella C Ofili, Ebidenara B Warekoromor, Nwanneka L Edigbue, Ufoma V Esiekpe, Dabrechi E Akaenyi, Gladys O Ag. Reversal and Preventive Pleiotropic Mechanisms Involved in the Antipsychotic-Like Effect of Taurine, an Essential β-Amino Acid in Ketamine-Induced Experimental Schizophrenia in Mice. Neurochemical research. 2022-11-09. PMID:36350433. |
taurine reduced ketamine-induced dopamine and 5-hydroxytryptamine changes, and increased gad and bdnf levels in the striatum, prefrontal-cortex and hippocampus, suggesting increased gabaergic and neurotrophic transmissions. |
2022-11-09 |
2023-08-14 |
mouse |
| Hakimeh Saadati, Safa Ghaheri, Farshid Sadegzadeh, Nona Sakhaie, Maryam Abdollahzade. Beneficial effects of enriched environment on behavior, cognitive functions, and hippocampal BDNF level following postnatal serotonin depletion in male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-11-07. PMID:36342785. |
beneficial effects of enriched environment on behavior, cognitive functions, and hippocampal bdnf level following postnatal serotonin depletion in male rats. |
2022-11-07 |
2023-08-14 |
rat |
| Hakimeh Saadati, Safa Ghaheri, Farshid Sadegzadeh, Nona Sakhaie, Maryam Abdollahzade. Beneficial effects of enriched environment on behavior, cognitive functions, and hippocampal BDNF level following postnatal serotonin depletion in male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-11-07. PMID:36342785. |
therefore, the present study aimed to evaluate the influences of the ee housing (postnatal day: pnd21-60) following postnatal serotonin depletion (by para-chlorophenylalanine: pcpa, 100mg/kg, s.c, in pnd 10-20) on anxiety-related behaviors, cognitive functions, and brain-derived neurotrophic factor (bdnf) mrna expression in the hippocampus of male rats. |
2022-11-07 |
2023-08-14 |
rat |
| Hakimeh Saadati, Safa Ghaheri, Farshid Sadegzadeh, Nona Sakhaie, Maryam Abdollahzade. Beneficial effects of enriched environment on behavior, cognitive functions, and hippocampal BDNF level following postnatal serotonin depletion in male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-11-07. PMID:36342785. |
the findings of the present work indicated that adolescent ee exposure alleviated memory impairment, decreased bdnf levels, and anxiety disorders induced by experimental depletion of serotonin. |
2022-11-07 |
2023-08-14 |
rat |
| Bich Phuong Bui, Phuong Linh Nguyen, Ha Thi Thu Do, Jungsook Ch. Anxiolytic effect of Korean Red Ginseng through upregulation of serotonin and GABA transmission and BDNF expression in immobilized mice. Journal of ginseng research. vol 46. issue 6. 2022-10-31. PMID:36312738. |
anxiolytic effect of korean red ginseng through upregulation of serotonin and gaba transmission and bdnf expression in immobilized mice. |
2022-10-31 |
2023-08-14 |
mouse |
| Bich Phuong Bui, Phuong Linh Nguyen, Ha Thi Thu Do, Jungsook Ch. Anxiolytic effect of Korean Red Ginseng through upregulation of serotonin and GABA transmission and BDNF expression in immobilized mice. Journal of ginseng research. vol 46. issue 6. 2022-10-31. PMID:36312738. |
the present study investigated the effect of krg on immobilization-induced anxiety-like behaviors in mice and explored the involvement of the serotonin and gaba systems and bdnf in the anxiolytic action. |
2022-10-31 |
2023-08-14 |
mouse |
| Elena M Kondaurova, Irina I Belokopytova, Elisabeth A Kulikova, Nikita V Khotskin, Tatiana V Ilchibaeva, Anton S Tsybko, Nina K Popova, Vladimir S Naumenk. On the role of serotonin 5-HT Behavioural brain research. 2022-10-24. PMID:36280010. |
serotonin (5-ht) and brain-derived neurotrophic factor (bdnf) are known as key players in brain and behavioral plasticity and interact with each other. |
2022-10-24 |
2023-08-14 |
Not clear |
| Saara Ahmad, Arfa Azhar, Prashant Tikmani, Hamna Rafique, Asra Khan, Hanif Mesiya, Humera Saee. A randomized clinical trial to test efficacy of chamomile and saffron for neuroprotective and anti-inflammatory responses in depressive patients. Heliyon. vol 8. issue 10. 2022-10-11. PMID:36217471. |
long-term reduction of 5-ht may disseminate to high sensitivity of mdd and alters the level of bdnf. |
2022-10-11 |
2023-08-14 |
human |
| Tejesvi Mishra, Kandasamy Nagarajan, Praveen Kumar Dixit, Vinay Kuma. Neuroprotective potential of ferulic acid against cyclophosphamide-induced neuroinflammation and behavioral changes. Journal of food biochemistry. 2022-09-27. PMID:36166506. |
cyclophosphamide administration also reduced the activity of antioxidant enzymes, reduced the level of neurotransmitters (i.e., dopamine, 5-ht, and bdnf), anti-inflammatory cytokines (il-10), and increased lipid peroxidation and proinflammatory cytokines (il-1β, il-6, and tnf-α). |
2022-09-27 |
2023-08-14 |
mouse |
| Peng-Ning Wu, Shuai Xiong, Peng Zhong, Wan-Qing Yang, Min Chen, Tai-Chun Tan. Global trends in research on irritable bowel syndrome and the brain-gut axis: Bibliometrics and visualization analysis. Frontiers in pharmacology. vol 13. 2022-09-26. PMID:36160395. |
furthermore, the physiological and pathological mechanisms of the brain-gut axis influencing ibs (related to gastrointestinal dysfunction, vagus nerve, visceral pain, intestinal flora, serotonin, tryptophan metabolism, stress, brain-derived neurotrophic factor (bdnf), and malonyldialdehyde) are the future research trends, especially the mechanisms related to intestinal flora. |
2022-09-26 |
2023-08-14 |
Not clear |