| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Flóra Gölöncsér, Mária Baranyi, Pál Tod, Fruzsina Maácz, Beáta Sperlág. P2X7 receptor inhibition alleviates mania-like behavior independently of interleukin-1β. iScience. vol 27. issue 3. 2024-03-06. PMID:38444608. |
amph increased il-10, tnf-α, and tbars levels, but did not influence bdnf levels, serotonin, dopamine, and noradrenaline content in brain tissues in either genotypes. |
2024-03-06 |
2024-03-08 |
mouse |
| Yuhua Jin, Lamei Yu, Yan L. Paroxetine Effect on Nerve Growth Factor, Human Neurotrophin-4, Brain-Derived Neurotrophic Factor Levels in Post-stroke Depression. Molecular neurobiology. 2024-03-05. PMID:38443730. |
the levels of ngf, nt-4, bdnf, 5-hydroxytryptamine (5-ht), homocysteine (hcy), noradrenaline (ne), hamilton depression scale (hamd) changes of national institute of health stroke scale (nihss). |
2024-03-05 |
2024-03-08 |
human |
| Yuhua Jin, Lamei Yu, Yan L. Paroxetine Effect on Nerve Growth Factor, Human Neurotrophin-4, Brain-Derived Neurotrophic Factor Levels in Post-stroke Depression. Molecular neurobiology. 2024-03-05. PMID:38443730. |
for post-stroke depression, paroxetine treatment can effectively improve ngf, nt-4, bdnf, 5-ht, hcy, and ne levels and effectively reduce the degree of neurological damage and depression, which has high clinical application value. |
2024-03-05 |
2024-03-08 |
human |
| Ping Yang, Sheng Huang, Zhihong Luo, Shaoming Zhou, Changjuan Zhang, Yong Zhu, Jingjing Yang, Liang L. Radix Bupleuri aqueous extract attenuates MK801-induced schizophrenia-like symptoms in mice: Participation of intestinal flora. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 172. 2024-02-16. PMID:38364739. |
radix bupleuri aqueous extract significantly improved the aberrant behaviors and neuronal damage in scz mice, upregulated syp and psd-95 expression and bdnf levels in hippocampal homogenates, down-regulated da and 5-ht levels, and suppressed microglial activation in scz mice. |
2024-02-16 |
2024-02-19 |
mouse |
| Ping Yang, Sheng Huang, Zhihong Luo, Shaoming Zhou, Changjuan Zhang, Yong Zhu, Jingjing Yang, Liang L. Radix Bupleuri aqueous extract attenuates MK801-induced schizophrenia-like symptoms in mice: Participation of intestinal flora. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 172. 2024-02-16. PMID:38364739. |
lactobacillus abundance was decreased in scz mice and reversed by radix bupleuri aqueous extract administration which exhibited a significant negative correlation with il-6, il-1β, da, and 5-ht, and a significant positive correlation with bdnf levels in hippocampal tissues. |
2024-02-16 |
2024-02-19 |
mouse |
| Ping Yang, Sheng Huang, Zhihong Luo, Shaoming Zhou, Changjuan Zhang, Yong Zhu, Jingjing Yang, Liang L. Radix Bupleuri aqueous extract attenuates MK801-induced schizophrenia-like symptoms in mice: Participation of intestinal flora. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 172. 2024-02-16. PMID:38364739. |
it was reversed by radix bupleuri aqueous extract administration, which exhibited a positive correlation with il-6, il-1β, and 5-ht and a negative correlation with bdnf. |
2024-02-16 |
2024-02-19 |
mouse |
| Kavitha Ukkirapandian, Kayalvizhi Elumalai, Karthika Priyadharshini Udaykumar, Sundaravadivel Vp, Muthulakshmi Rangasm. Behavioral and Biochemical Assays for Autism Models of Wistar Rats. Cureus. vol 16. issue 1. 2024-02-13. PMID:38344592. |
the estimation of antioxidant profile (malondialdehyde {mda}, glutathione {gsh}, catalase (cat), and superoxide dismutase {sod}), proinflammatory markers (tumor necrosis factor {tnf} alpha, transforming growth factor {tgf} beta, interleukin {il} 6, and il-1 beta), neurotransmitters (gamma-aminobutyric acid {gaba} and serotonin), and brain-derived neurotrophic factor (bdnf) in the hippocampal region was done. |
2024-02-13 |
2024-02-15 |
rat |
| Mina Sadighi, Lingling Mai, Yifan Xu, Morgane Boillot, Giorgia Targa, Francesca Mottarlini, Paolo Brambilla, Peter Gass, Lucia Caffino, Fabio Fumagalli, Judith R Homber. Chronic exposure to imipramine induces a switch from depression-like to mania-like behavior in female serotonin transporter knockout rats: Role of BDNF signaling in the infralimbic cortex. Journal of affective disorders. 2024-01-27. PMID:38280571. |
chronic exposure to imipramine induces a switch from depression-like to mania-like behavior in female serotonin transporter knockout rats: role of bdnf signaling in the infralimbic cortex. |
2024-01-27 |
2024-01-30 |
rat |
| Xiaoyang Ma, Jeong-Woo Shin, Jae-Hyun Cho, Seung-Won Han, Dong-Hyun Ki. IL-6 expression-suppressing Lactobacillus reuteri strains alleviate gut microbiota-induced anxiety and depression in mice. Letters in applied microbiology. 2023-12-21. PMID:38126116. |
here, we investigated the effects of six lactobacillus reuteri strains on bdnf, serotonin, and il-6 expression in neuronal or macrophage cells and pdi fecal microbiota-cultured microbiota (pcm)-induced depression in mice. |
2023-12-21 |
2023-12-23 |
mouse |
| Xiaoyang Ma, Jeong-Woo Shin, Jae-Hyun Cho, Seung-Won Han, Dong-Hyun Ki. IL-6 expression-suppressing Lactobacillus reuteri strains alleviate gut microbiota-induced anxiety and depression in mice. Letters in applied microbiology. 2023-12-21. PMID:38126116. |
of these strains, l6 most potently increased bdnf and serotonin levels in corticosterone-stimulated sh-sy5ycells and pc12 cells, followed by l3. |
2023-12-21 |
2023-12-23 |
mouse |
| Xiaoyang Ma, Jeong-Woo Shin, Jae-Hyun Cho, Seung-Won Han, Dong-Hyun Ki. IL-6 expression-suppressing Lactobacillus reuteri strains alleviate gut microbiota-induced anxiety and depression in mice. Letters in applied microbiology. 2023-12-21. PMID:38126116. |
when l1 (weakest in vitro), l3, and l6 were orally administered in mice with pcm-induced depression, l6 most potently suppressed depression-like behaviors and hippocampal tnf-α and il-6 expression and increased hippocampal serotonin, bdnf, 5ht7, gabaarα1, and gababr1b expression, followed by l3 and l1. |
2023-12-21 |
2023-12-23 |
mouse |
| Xiaoyang Ma, Jeong-Woo Shin, Jae-Hyun Cho, Seung-Won Han, Dong-Hyun Ki. IL-6 expression-suppressing Lactobacillus reuteri strains alleviate gut microbiota-induced anxiety and depression in mice. Letters in applied microbiology. 2023-12-21. PMID:38126116. |
bdnf or serotonin levels in corticosterone-stimulated neuronal cells were negatively correlated with depression-related biomarkers in pcm-transplanted mice, while il-6 levels in lps-stimulated macrophage were positively correlated. |
2023-12-21 |
2023-12-23 |
mouse |
| Handan Deng, Yongjun Yu, Qi Sha, Weiyi Sun, Lundan Liang, Feier Ren, Hua Ji, Xiangdi Shen, Xingli Fa. Construction of antibiotic-induced depression mice model and the function of intestinal microbiota. Frontiers in microbiology. vol 14. 2023-12-13. PMID:38088959. |
by using these antibiotics, the concentrations of norepinephrine (ne), 5-hydroxytryptamine (5-ht), and brain-derived neurotrophic factor (bdnf) in mice hippocampus and prefrontal cortex tissues were significantly decreased. |
2023-12-13 |
2023-12-17 |
mouse |
| Naif H Ali, Hayder M Al-Kuraishy, Ali I Al-Gareeb, Ali K Albuhadily, Rabab S Hamad, Athanasios Alexiou, Marios Papadakis, Hebatallah M Saad, Gaber El-Saber Batih. Role of brain renin-angiotensin system in depression: A new perspective. CNS neuroscience & therapeutics. 2023-11-13. PMID:37953501. |
dysregulation of brain ras triggers the development and progression of depression through the reduction of brain 5ht and expression of brain-derived neurotrophic factor (bdnf) and the induction of mitochondrial dysfunction, oxidative stress, and neuroinflammation. |
2023-11-13 |
2023-11-20 |
Not clear |
| Naif H Ali, Hayder M Al-Kuraishy, Ali I Al-Gareeb, Ali K Albuhadily, Rabab S Hamad, Athanasios Alexiou, Marios Papadakis, Hebatallah M Saad, Gaber El-Saber Batih. Role of brain renin-angiotensin system in depression: A new perspective. CNS neuroscience & therapeutics. 2023-11-13. PMID:37953501. |
therefore, inhibition of central classical ras by arbs and aceis and activation of non-classical ras prevent the development of depression by regulating 5ht, bdnf, mitochondrial dysfunction, oxidative stress, and neuroinflammation. |
2023-11-13 |
2023-11-20 |
Not clear |
| Doaa S Ibrahim, Eman M S Shahe. Effect of royal jelly on acrylamide-induced neurotoxicity in rats. Journal of chemical neuroanatomy. 2023-11-04. PMID:37925036. |
the administration of aa increased the level of malondialdehyde (mda), decreases levels of haematological parameters, superoxide dismutase (sod), reduced glutathione (gsh), brain-derived neurotrophic factor (bdnf), neurotransmitters (serotonin, dopamine, and acetylcholine), and cleaved caspase-3, as well as increase the damage to the brain tissues. |
2023-11-04 |
2023-11-08 |
rat |
| Nuo Chen, Ming Zhao, Yaxin Guo, Nan Wu, Baihui Cao, Bing Zhan, Tian Zhou, Yubin Li, Faliang Zhu, WanJun Chen, Yan Li, Lining Zhan. D-mannose is a rapid inducer of ACSS2 to trigger rapid and long-lasting antidepressant responses through augmenting BDNF and TPH2 levels. Translational psychiatry. vol 13. issue 1. 2023-11-02. PMID:37914710. |
the potentiation of synaptic plasticity and serotonin generation by brain-derived neurotrophic factor (bdnf) and tryptophan hydroxylase 2 (tph2) is well characterized to facilitate rapid and long-lasting antidepressant actions. |
2023-11-02 |
2023-11-08 |
mouse |
| Sen Yang, Qiang Zheng, Guoan Yi. A 24-h restraint with food and water deprivation: a potential method to establish a model of depression in pigs. Frontiers in veterinary science. vol 10. 2023-10-26. PMID:37876629. |
the levels of cor and acth in the serum and the levels of 5-ht, ne, and bdnf in the hippocampus and medial prefrontal cortex were detected using elisa to identify the physiological state. |
2023-10-26 |
2023-11-08 |
Not clear |
| Xiaoyan Peng, Sujuan Feng, Poxuan Zhang, Shengmei Sang, Yi Zhan. Analysis of influencing factors of anxiety and depression in maintenance hemodialysis patients and its correlation with BDNF, NT-3 and 5-HT levels. PeerJ. vol 11. 2023-09-26. PMID:37750080. |
analysis of influencing factors of anxiety and depression in maintenance hemodialysis patients and its correlation with bdnf, nt-3 and 5-ht levels. |
2023-09-26 |
2023-10-07 |
Not clear |
| Xiaoyan Peng, Sujuan Feng, Poxuan Zhang, Shengmei Sang, Yi Zhan. Analysis of influencing factors of anxiety and depression in maintenance hemodialysis patients and its correlation with BDNF, NT-3 and 5-HT levels. PeerJ. vol 11. 2023-09-26. PMID:37750080. |
the aim of this study is to examine the factors that contribute to anxiety and depression in individuals undergoing maintenance hemodialysis (mhd), as well as their association with serum levels of brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3), and serotonin (5-ht). |
2023-09-26 |
2023-10-07 |
Not clear |