| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gary Lynch, Eniko A Kramar, Christopher S Rex, Yousheng Jia, Danielle Chappas, Christine M Gall, Danielle A Simmon. Brain-derived neurotrophic factor restores synaptic plasticity in a knock-in mouse model of Huntington's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 16. 2007-05-07. PMID:17442827. |
the decrease in actin polymerization and deficits in ltp stabilization were reversed by bdnf, concentrations of which were substantially reduced in hippocampus of both hdh(q92) and hdh(q111) mice. |
2007-05-07 |
2023-08-12 |
mouse |
| Song Li, Che Wang, Minwei Wang, Wei Li, Kinzo Matsumoto, Yiyuan Tan. Antidepressant like effects of piperine in chronic mild stress treated mice and its possible mechanisms. Life sciences. vol 80. issue 15. 2007-04-25. PMID:17289085. |
furthermore, the decreased proliferation of hippocampal progenitor cells was ameliorated and the level of brain-derived neurotrophic factor (bdnf) in hippocampus of cms stressed mice was up-regulated by piperine treatment in the same time course. |
2007-04-25 |
2023-08-12 |
mouse |
| Song Li, Che Wang, Minwei Wang, Wei Li, Kinzo Matsumoto, Yiyuan Tan. Antidepressant like effects of piperine in chronic mild stress treated mice and its possible mechanisms. Life sciences. vol 80. issue 15. 2007-04-25. PMID:17289085. |
treatment with piperine (6.25-25 microm) for 72 h reversed the cort-induced reduction of bdnf mrna expression in cultured hippocampal neurons. |
2007-04-25 |
2023-08-12 |
mouse |
| Song Li, Che Wang, Minwei Wang, Wei Li, Kinzo Matsumoto, Yiyuan Tan. Antidepressant like effects of piperine in chronic mild stress treated mice and its possible mechanisms. Life sciences. vol 80. issue 15. 2007-04-25. PMID:17289085. |
in summary, up-regulation of the progenitor cell proliferation of hippocampus and cytoprotective activity might be mechanisms involved in the antidepressant-like effect of piperine, which may be closely related to the elevation of hippocampal bdnf level. |
2007-04-25 |
2023-08-12 |
mouse |
| Lionel Müller Igaz, Milena Winograd, Martín Cammarota, Luciana A Izquierdo, Mariana Alonso, Iván Izquierdo, Jorge H Medin. Early activation of extracellular signal-regulated kinase signaling pathway in the hippocampus is required for short-term memory formation of a fear-motivated learning. Cellular and molecular neurobiology. vol 26. issue 4-6. 2007-04-24. PMID:16977492. |
together with our previous findings showing a rapid decrease in erk2 activation and impaired stm after blocking bdnf function, the present results strongly suggest that erk2 signaling in the hippocampus is a critical step in stm processing. |
2007-04-24 |
2023-08-12 |
rat |
| Jorge G Ramos, Jorgelina Varayoud, Lucas Monje, Guillermo Moreno-Piovano, Mónica Muñoz-de-Toro, Enrique H Luqu. Diethylstilbestrol alters the population dynamic of neural precursor cells in the neonatal male rat dentate gyrus. Brain research bulletin. vol 71. issue 6. 2007-04-23. PMID:17292805. |
furthermore, vascular endothelial growth factor (vegf) and brain-derived neurotrophic factor (bdnf) mrna expression was evaluated in hippocampal tissue blocks by real time rt-pcr. |
2007-04-23 |
2023-08-12 |
rat |
| Michelle D Amaral, Christopher A Chapleau, Lucas Pozzo-Mille. Transient receptor potential channels as novel effectors of brain-derived neurotrophic factor signaling: potential implications for Rett syndrome. Pharmacology & therapeutics. vol 113. issue 2. 2007-04-19. PMID:17118456. |
outlined in the following review is a synopsis of neurotrophin signaling with a particular focus upon brain-derived neurotrophic factor (bdnf) and its role in hippocampal synaptic plasticity and neuronal ca(2+) homeostasis. |
2007-04-19 |
2023-08-12 |
Not clear |
| Catharine H Duman, Lee Schlesinger, Masafumi Kodama, David S Russell, Ronald S Duma. A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment. Biological psychiatry. vol 61. issue 5. 2007-04-17. PMID:16945347. |
brain-derived neurotrophic factor (bdnf) is upregulated in the hippocampus by antidepressant treatments, and centrally administered bdnf can produce antidepressant-like effects in rodent behavioral models of depression. |
2007-04-17 |
2023-08-12 |
Not clear |
| Eero Castrén, Vootele Võikar, Tomi Rantamäk. Role of neurotrophic factors in depression. Current opinion in pharmacology. vol 7. issue 1. 2007-04-12. PMID:17049922. |
stress suppresses brain-derived neurotrophic factor (bdnf) synthesis in the hippocampus, at least partially through a sustained modification of chromatin structure. |
2007-04-12 |
2023-08-12 |
Not clear |
| Eero Castrén, Vootele Võikar, Tomi Rantamäk. Role of neurotrophic factors in depression. Current opinion in pharmacology. vol 7. issue 1. 2007-04-12. PMID:17049922. |
essentially all antidepressant treatments increase bdnf synthesis and signaling in the hippocampus and prefrontal cortex. |
2007-04-12 |
2023-08-12 |
Not clear |
| Eero Castrén, Vootele Võikar, Tomi Rantamäk. Role of neurotrophic factors in depression. Current opinion in pharmacology. vol 7. issue 1. 2007-04-12. PMID:17049922. |
this signaling is required for the behavioral effects of antidepressant drugs in rodents, and increased bdnf levels in the hippocampus mimic the behavioral effects of antidepressants. |
2007-04-12 |
2023-08-12 |
Not clear |
| C Engesser-Cesar, A J Anderson, C W Cotma. Wheel running and fluoxetine antidepressant treatment have differential effects in the hippocampus and the spinal cord. Neuroscience. vol 144. issue 3. 2007-04-11. PMID:17137724. |
exercise and antidepressants used independently have been shown to increase hippocampal brain-derived neurotrophic factor (bdnf) and neurogenesis. |
2007-04-11 |
2023-08-12 |
mouse |
| C Engesser-Cesar, A J Anderson, C W Cotma. Wheel running and fluoxetine antidepressant treatment have differential effects in the hippocampus and the spinal cord. Neuroscience. vol 144. issue 3. 2007-04-11. PMID:17137724. |
using c57bl/10 female mice, bdnf protein, insulin-like growth factor 1 (igf-1) protein and neurogenesis were measured in the hippocampus after 21 days of wheel running, 21 days of fluoxetine antidepressant therapy (daily i.p. |
2007-04-11 |
2023-08-12 |
mouse |
| C Engesser-Cesar, A J Anderson, C W Cotma. Wheel running and fluoxetine antidepressant treatment have differential effects in the hippocampus and the spinal cord. Neuroscience. vol 144. issue 3. 2007-04-11. PMID:17137724. |
bdnf protein and cytogenesis/neurogenesis increased in the hippocampus with fluoxetine (high dose), but not wheel running. |
2007-04-11 |
2023-08-12 |
mouse |
| C Engesser-Cesar, A J Anderson, C W Cotma. Wheel running and fluoxetine antidepressant treatment have differential effects in the hippocampus and the spinal cord. Neuroscience. vol 144. issue 3. 2007-04-11. PMID:17137724. |
results showed that bdnf, igf-1 and neurogenesis behave independently in the hippocampus and spinal cord. |
2007-04-11 |
2023-08-12 |
mouse |
| C Engesser-Cesar, A J Anderson, C W Cotma. Wheel running and fluoxetine antidepressant treatment have differential effects in the hippocampus and the spinal cord. Neuroscience. vol 144. issue 3. 2007-04-11. PMID:17137724. |
thus, the hippocampus and the spinal cord respond in distinct ways to wheel running and fluoxetine, and a prior induction of bdnf, igf-1 or cytogenesis is unlikely to be the mechanism for wheel running providing a margin of protection against sci. |
2007-04-11 |
2023-08-12 |
mouse |
| M J Chen, T V Nguyen, C J Pike, A A Russo-Neustad. Norepinephrine induces BDNF and activates the PI-3K and MAPK cascades in embryonic hippocampal neurons. Cellular signalling. vol 19. issue 1. 2007-04-10. PMID:16876982. |
norepinephrine induces bdnf and activates the pi-3k and mapk cascades in embryonic hippocampal neurons. |
2007-04-10 |
2023-08-12 |
Not clear |
| M J Chen, T V Nguyen, C J Pike, A A Russo-Neustad. Norepinephrine induces BDNF and activates the PI-3K and MAPK cascades in embryonic hippocampal neurons. Cellular signalling. vol 19. issue 1. 2007-04-10. PMID:16876982. |
both antidepressant treatment and physical exercise have been shown to increase circulating levels of norepinephine (ne) and hippocampal brain-derived neurotrophic factor (bdnf). |
2007-04-10 |
2023-08-12 |
Not clear |
| M J Chen, T V Nguyen, C J Pike, A A Russo-Neustad. Norepinephrine induces BDNF and activates the PI-3K and MAPK cascades in embryonic hippocampal neurons. Cellular signalling. vol 19. issue 1. 2007-04-10. PMID:16876982. |
using isolated embryonic hippocampal neurons and immunoblotting, we show that application of ne increases bdnf and phosphorylated trk, and that these increases can be prevented by erk and pi-3k inhibitors. |
2007-04-10 |
2023-08-12 |
Not clear |
| Shih-Jen Tsa. TrkB partial agonists: potential treatment strategy for major depression. Medical hypotheses. vol 68. issue 3. 2007-04-05. PMID:16905274. |
evidence suggests that low central bdnf activity, especially in the hippocampus, may play a pivotal role in the pathophysiology of major depression, and that agents that can increase bdnf-trkb pathway signaling may be therapeutic for this disease. |
2007-04-05 |
2023-08-12 |
Not clear |