| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Márcia M T Moraes, Marcella C Galvão, Danilo Cabral, Cideli P Coelho, Nicolle Queiroz-Hazarbassanov, Maria F M Martins, Eduardo F Bondan, Maria M Bernardi, Thiago Berti Kirste. Propentofylline Prevents Sickness Behavior and Depressive-Like Behavior Induced by Lipopolysaccharide in Rats via Neuroinflammatory Pathway. PloS one. vol 12. issue 1. 2017-08-28. PMID:28056040. |
anxiety-like behavior (light-dark test), depressive-like behavior (forced swim test), plasmatic levels of the brain-derived neurotrophic factor (bdnf, depression biomarker), and central glial fibrillary acidic protein (gfap) expression (an astrocyte biomarker) were also evaluated. |
2017-08-28 |
2023-08-13 |
rat |
| Christiane Reick, Gisa Ellrichmann, Teresa Tsai, De-Hyung Lee, Stefan Wiese, Ralf Gold, Carsten Saft, Ralf A Linke. Expression of brain-derived neurotrophic factor in astrocytes - Beneficial effects of glatiramer acetate in the R6/2 and YAC128 mouse models of Huntington's disease. Experimental neurology. vol 285. issue Pt A. 2017-05-08. PMID:27587303. |
we show that ga increases the expression of functionally active bdnf in astrocyte culture and in astrocytes of ga treated hd mice. |
2017-05-08 |
2023-08-13 |
mouse |
| Shotaro Otsuka, Harutoshi Sakakima, Megumi Sumizono, Seiya Takada, Takuto Terashi, Yoshihiro Yoshid. The neuroprotective effects of preconditioning exercise on brain damage and neurotrophic factors after focal brain ischemia in rats. Behavioural brain research. vol 303. 2016-12-13. PMID:26808606. |
our findings suggest that preconditioning exercise reduced the infract volume and ameliorated motor function, enhanced expression levels of mk and bdnf, increased astrocyte proliferation, increased angiogenesis, and reduced neuronal apoptosis and oxidative stress. |
2016-12-13 |
2023-08-13 |
rat |
| Wenjuan Yu, Hao Zhu, Yueming Wang, Guanjun Li, Lihua Wang, Huafang L. Reactive Transformation and Increased BDNF Signaling by Hippocampal Astrocytes in Response to MK-801. PloS one. vol 10. issue 12. 2016-08-17. PMID:26700309. |
moreover, the expression levels of bdnf and its receptors trkb and p75 were examined in mk-801-treated astrocyte cultures. |
2016-08-17 |
2023-08-13 |
rat |
| Damián Dorfman, Marcos L Aranda, Ruth E Rosenstei. Enriched Environment Protects the Optic Nerve from Early Diabetes-Induced Damage in Adult Rats. PloS one. vol 10. issue 8. 2016-05-12. PMID:26312758. |
anterograde transport, retinal morphology, optic nerve axons (toluidine blue staining and phosphorylated neurofilament heavy immunoreactivity), microglia/macrophages (ionized calcium binding adaptor molecule 1 (iba-1) immunoreactivity), astrocyte reactivity (glial fibrillary acid protein-immunostaining), myelin (myelin basic protein immunoreactivity), ultrastructure, and brain derived neurotrophic factor (bdnf) levels were assessed in non-diabetic and diabetic animals housed in se or ee. |
2016-05-12 |
2023-08-13 |
rat |
| Boris Görg, Ayse Karababa, Aygul Shafigullina, Hans J Bidmon, Dieter Häussinge. Ammonia-induced senescence in cultured rat astrocytes and in human cerebral cortex in hepatic encephalopathy. Glia. vol 63. issue 1. 2015-09-14. PMID:25092802. |
concurrently, nh4 cl (5 mmol/l) treatment inhibited both epidermal growth factor- and brain-derived neurotrophic factor (bdnf)-induced proliferation as well as bdnf-mediated astrocyte morphology changes through downregulation of the respective growth factor receptors epidermal growth factor receptor and truncated tyrosine receptor kinase b. |
2015-09-14 |
2023-08-13 |
human |
| L Pietranera, M E Brocca, P Roig, A Lima, L M Garcia-Segura, A F De Nicol. 17α-Oestradiol-induced neuroprotection in the brain of spontaneously hypertensive rats. Journal of neuroendocrinology. vol 26. issue 5. 2014-12-08. PMID:24730417. |
in the brain, we analysed steroid effects on hippocampus ki67+ proliferating cells, doublecortin (dcx) positive neuroblasts, glial fibrillary acidic protein (gfap)+ astrocyte density, aromatase immunostaining and brain-derived neurotrophic factor (bdnf) mrna. |
2014-12-08 |
2023-08-13 |
rat |
| Ruiguo Zhang, Zhengwu Peng, Huaihai Wang, Fen Xue, Yihuan Chen, Ying Wang, Huaning Wang, Qingrong Ta. Gastrodin ameliorates depressive-like behaviors and up-regulates the expression of BDNF in the hippocampus and hippocampal-derived astrocyte of rats. Neurochemical research. vol 39. issue 1. 2014-09-09. PMID:24293261. |
gastrodin ameliorates depressive-like behaviors and up-regulates the expression of bdnf in the hippocampus and hippocampal-derived astrocyte of rats. |
2014-09-09 |
2023-08-12 |
rat |
| Ruiguo Zhang, Zhengwu Peng, Huaihai Wang, Fen Xue, Yihuan Chen, Ying Wang, Huaning Wang, Qingrong Ta. Gastrodin ameliorates depressive-like behaviors and up-regulates the expression of BDNF in the hippocampus and hippocampal-derived astrocyte of rats. Neurochemical research. vol 39. issue 1. 2014-09-09. PMID:24293261. |
the purpose of the present study was to assess the effects of gas on alleviating depressive-like behaviors in a rat model of chronic unpredictable stress (cus) and regulating the expression of bdnf in the hippocampus and hippocampal-derived astrocyte from sprague-dawley (sd) rats. |
2014-09-09 |
2023-08-12 |
rat |
| Ruiguo Zhang, Zhengwu Peng, Huaihai Wang, Fen Xue, Yihuan Chen, Ying Wang, Huaning Wang, Qingrong Ta. Gastrodin ameliorates depressive-like behaviors and up-regulates the expression of BDNF in the hippocampus and hippocampal-derived astrocyte of rats. Neurochemical research. vol 39. issue 1. 2014-09-09. PMID:24293261. |
the changes of the astrocyte activation and the level of bdnf may play a critical role in the pharmacological action of gas. |
2014-09-09 |
2023-08-12 |
rat |
| C Lin, C-J Wu, I-H Wei, M-H Tsai, N-W Chang, T-T Yang, Y-M Ku. Chronic treadmill running protects hippocampal neurons from hypobaric hypoxia-induced apoptosis in rats. Neuroscience. vol 231. 2013-07-25. PMID:23219906. |
ex decreased the hypoxia-induced elevations of hif-1α (p<0.001, n=5), nnos (p<0.001, n=5) and inos (p<0.001, n=5) levels and activation of microglia (p=0.005, n=3) and astrocyte (p<0.001, n=5) status; whereas the hypoxia-reduced bdnf protein levels (p=0.013, n=5) were restored. |
2013-07-25 |
2023-08-12 |
rat |
| Adriana Fernanda Vizuete, Daniela Fraga de Souza, Maria Cristina Guerra, Cristiane Batassini, Márcio Ferreira Dutra, Caren Bernardi, Ana Paula Costa, Carlos-Alberto Gonçalve. Brain changes in BDNF and S100B induced by ketogenic diets in Wistar rats. Life sciences. vol 92. issue 17-19. 2013-06-20. PMID:23557853. |
we investigated the effects of ketogenic diet (kd) on levels of tumor necrosis factor alpha (tnf-α, a classical pro-inflammatory cytokine), bdnf (brain-derived neurotrophic factor, commonly associated with synaptic plasticity), and s100b, an astrocyte neurotrophic cytokine involved in metabolism regulation. |
2013-06-20 |
2023-08-12 |
rat |
| S D Crish, J D Dapper, S E MacNamee, P Balaram, T N Sidorova, W S Lambert, D J Calkin. Failure of axonal transport induces a spatially coincident increase in astrocyte BDNF prior to synapse loss in a central target. Neuroscience. vol 229. 2013-06-06. PMID:23159315. |
failure of axonal transport induces a spatially coincident increase in astrocyte bdnf prior to synapse loss in a central target. |
2013-06-06 |
2023-08-12 |
mouse |
| Satoshi Nishino, Koji Ohtomo, Yukio Numata, Tadahiro Sato, Norimichi Nakahata, Masatake Kurit. Divergent effects of lithium and sodium valproate on brain-derived neurotrophic factor (BDNF) production in human astrocytoma cells at therapeutic concentrations. Progress in neuro-psychopharmacology & biological psychiatry. vol 39. issue 1. 2013-01-21. PMID:21803112. |
we suggest the possibility that vpa and li have divergent effects on astrocyte bdnf production. |
2013-01-21 |
2023-08-12 |
human |
| Hao Yang, Guo-Dong Feng, Zhe Liang, Angela Vitale, Xi-Ying Jiao, Gong Ju, Si-Wei Yo. In vitro beneficial activation of microglial cells by mechanically-injured astrocytes enhances the synthesis and secretion of BDNF through p38MAPK. Neurochemistry international. vol 61. issue 2. 2012-12-07. PMID:22561407. |
in this study, we demonstrated that mechanically-injured astrocyte conditioned medium (acm) could provoke beneficial activation of microglial cells and thus promote the transcription, synthesis and release of bdnf in cultured microglial cells. |
2012-12-07 |
2023-08-12 |
Not clear |
| Tin-Tin Win-Shwe, Naoki Kunugita, Yasuhiro Yoshida, Daisuke Nakajima, Shinji Tsukahara, Hidekazu Fujimak. Differential mRNA expression of neuroimmune markers in the hippocampus of infant mice following toluene exposure during brain developmental period. Journal of applied toxicology : JAT. vol 32. issue 2. 2012-05-23. PMID:21381054. |
in contrast, ngf and brain-derived neurotrophic factor (bdnf) and proinflammatory cytokines tnf-α, ccl3, nf-κb, toll-like receptor (tlr)-4, astrocyte marker glial fibrillary acidic protein (gfap), and microglia marker ionized calcium binding adapter molecule (iba)-1 mrnas were increased significantly in mice exposed to 5 ppm toluene on pnd 8-12. |
2012-05-23 |
2023-08-12 |
mouse |
| Leticia Arregui, Jorge A Benítez, Luis F Razgado, Paula Vergara, Jose Segovi. Adenoviral astrocyte-specific expression of BDNF in the striata of mice transgenic for Huntington's disease delays the onset of the motor phenotype. Cellular and molecular neurobiology. vol 31. issue 8. 2012-05-14. PMID:21681558. |
considering the extensive gliosis and the survival effects of bdnf, we constructed an adenovirus to express a bdnf cdna in astrocyte cells using a promoter of the glial fibrillary acidic protein gene. |
2012-05-14 |
2023-08-12 |
mouse |
| Yuanyuan Ye, Gaohua Wang, Huiling Wang, Xiaoping Wan. Brain-derived neurotrophic factor (BDNF) infusion restored astrocytic plasticity in the hippocampus of a rat model of depression. Neuroscience letters. vol 503. issue 1. 2012-01-18. PMID:21843601. |
in this paper, we investigated the effects of chronic unpredictable mild stress (cums) and bdnf infusion on astrocyte immunoreactivity in rat hippocampus using sucrose preference test, open field test, and western blot analysis. |
2012-01-18 |
2023-08-12 |
rat |
| Yuanyuan Ye, Gaohua Wang, Huiling Wang, Xiaoping Wan. Brain-derived neurotrophic factor (BDNF) infusion restored astrocytic plasticity in the hippocampus of a rat model of depression. Neuroscience letters. vol 503. issue 1. 2012-01-18. PMID:21843601. |
therefore, bdnf might restore astrocyte immunoreactivity in depressive-like rat hippocampus, providing insights into the potential pharmacological role of bdnf in stress-related disorders. |
2012-01-18 |
2023-08-12 |
rat |
| Kiren Ubhi, Edward Rockenstein, Michael Mante, Chandra Inglis, Anthony Adame, Christina Patrick, Kristen Whitney, Eliezer Maslia. Neurodegeneration in a transgenic mouse model of multiple system atrophy is associated with altered expression of oligodendroglial-derived neurotrophic factors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 18. 2010-06-02. PMID:20445049. |
in this context, the expression of a number neurotrophic factors reportedly expressed by oligodendrocytes [glial-derived neurotrophic factor (gdnf), brain-derived neurotrophic factor (bdnf), and insulin-like growth factor 1 (igf-1), as well as basic fibroblast growth factor 2 (bfgf2), reportedly astrocyte derived] were examined in transgenic mouse models expressing human alphasyn (halphasyn) under the control of either neuronal (pdgfbeta or mthy1) or oligodendrocytic (mbp) promoters. |
2010-06-02 |
2023-08-12 |
mouse |