| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fatemeh Mohtashaminia, Mohammad Reza Amini, Fatemeh Sheikhhossein, Kurosh Djafarian, Sakineh Shab-Bida. Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials. Clinical nutrition ESPEN. vol 49. 2022-05-27. PMID:35623810. |
therefore, the current systematic review and meta-analysis aimed to investigate the effect of berberis aristate and silybum marianum on alanine aminotransferase (alt) and aspartate aminotransferase (ast) in adults. |
2022-05-27 |
2023-08-13 |
Not clear |
| Yi-Hsueh Liu, Szu-Chia Chen, Wen-Hsien Lee, Ying-Chih Chen, Jiun-Chi Huang, Pei-Yu Wu, Chih-Hsing Hung, Chao-Hung Kuo, Ho-Ming S. Liver-function parameters are associated with incident hypertension in a large Taiwanese population follow-up study. Journal of human hypertension. 2022-05-26. PMID:35618874. |
we evaluated liver biomarkers, including aspartate aminotransferase (ast), alanine aminotransferase (alt), albumin, alpha-fetoprotein (afp), total bilirubin, and gamma-glutamyl transferase (ggt) in this study. |
2022-05-26 |
2023-08-13 |
human |
| Aimei Liu, Yaqin Yang, Jingchao Guo, Yan Gao, Qinghua Wu, Ling Zhao, Lv-Hui Sun, Xu Wan. Cytochrome P450 enzymes mediated by DNA methylation is involved in deoxynivalenol-induced hepatoxicity in piglets. Animal nutrition (Zhongguo xu mu shou yi xue hui). vol 9. 2022-05-23. PMID:35600548. |
don significantly raised the activity of aspartate aminotransferase (ast), alanine aminotransferase (alt), and glutamyl transpeptidase (ggt) ( |
2022-05-23 |
2023-08-13 |
Not clear |
| Tahir Karaşahin, Neşe Hayat Aksoy, Şükrü Dursun, Gaye Bulut, Ali Evren Haydardedeoğlu, Güzin Çamkerten, İlker Çamkerten, Ramazan İlgü. Effects of age and sex on some hematological and biochemical parameters in Hair goats. Veterinary research forum : an international quarterly journal. vol 13. issue 1. 2022-05-23. PMID:35601783. |
the levels of, albumin, total protein, globulin, glucose, total bilirubin, urea, creatinine, phosphorus, magnesium, calcium, aspartate aminotransferase (ast), alkaline phosphatase (alp), gamma-glutamyl transferase (ggt), creatine kinase (ck), alanine aminotransferase (alt) and iron levels were investigated in sera. |
2022-05-23 |
2023-08-13 |
Not clear |
| Guoliang Huang, Bingbing Chen, Yi Luo, Liming Chen, Shaojie Wu, Shijun Wan. Clinical Characteristics and Mathematical Analysis of Curative Effect of Hemodialysis in Curing Poisoning Caused by Snakebite. Scanning. vol 2022. 2022-05-23. PMID:35601870. |
experimental results show the following: compared with before treatment, patient's activated partial thromboplastin time (aptt) after treatment and the prothrombin time (pt) level decrease, fibrinogen (fib) levels are elevated, aspartate transferase (ast) and creatine kinase isoenzyme (ck-mb) level decreased, and the differences were statistically significant ( |
2022-05-23 |
2023-08-13 |
Not clear |
| Wenjing Ni, Yan Pan, Huijuan Yang, Wei Li, Yan Sun, Yu Xu, Weidong Che. [Saxagliptin alleviates kidney injury in diabetic rats by down-regulating the expression of mammalian target of rapamycin (mTOR)]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 38. issue 5. 2022-05-23. PMID:35603648. |
glucose (g1u), albumin (alb), aspartate transaminase (ast), alanine transaminase (alt), serum creatinine (scr), blood urea nitrogen (bun), uric acid (ua), serum total cholesterol (tc), triglycerides (tg) were detected by automatic biochemical analyzer. |
2022-05-23 |
2023-08-13 |
rat |
| Miao Shen, Hanghai Pan, Jinjing Ke, Fei Zha. NF-κB-upregulated miR-155-5p promotes hepatocyte mitochondrial dysfunction to accelerate the development of nonalcoholic fatty liver disease through downregulation of STC1. Journal of biochemical and molecular toxicology. 2022-05-23. PMID:35603999. |
next, the expression of nf-κb and stc1 was altered in the modeled rats through lentivirus injection, followed by determination on the levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), total cholesterol, triglycerides, and low-density lipoprotein cholesterol. |
2022-05-23 |
2023-08-13 |
rat |
| Lanlan Li, Zhe Liu, Jinqiang Quan, Junhao Lu, Guiyan Zhao, Jun Su. Dietary nanoselenium supplementation for heat-stressed rainbow trout: effects on organizational structure, lipid changes, and biochemical parameters as well as heat-shock-protein- and selenoprotein-related gene expression. Fish physiology and biochemistry. 2022-05-21. PMID:35597860. |
the results showed that, under heat stress, the fish supplementation of 5 mg/kg nano-se significantly increased liver glutathione peroxidase (gpx) activity and upregulated expression levels of hsp70b, hsp90a1, gpx1a, and trx mrnas, while liver alanine aminotransferase (alt), aspartate aminotransferase (ast), superoxide dismutase (sod), and malondialdehyde (mda) levels as well as tissue structure damage and lipid accumulation were decreased. |
2022-05-21 |
2023-08-13 |
Not clear |
| Gaber E El-Desoky, Saikh M Wabaidur, Zeid A AlOthman, Mohamed A Habil. Evaluation of Nano-curcumin effects against Tartrazine-induced abnormalities in liver and kidney histology and other biochemical parameters. Food science & nutrition. vol 10. issue 5. 2022-05-20. PMID:35592283. |
the liver function biomarkers are (glutamate oxaloacetate transaminase (got), glutamate pyruvate transaminase (gpt), alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma-glutamyl transaminase (ggt), alkaline phosphatase (alp), total bilirubin (t. bill)), whereas the kidney biomarkers are (creatinine, uric acid, urea, globulin, total protein (tp)), as well as blood parameters of (serum glucose (sglu), alpha-fetoprotein (afp), protein kinase-c (pkc)) and lipid profiles that include (total lipids (tl), triglyceride (tg), total cholesterol (tc), low-density lipoprotein-cholesterol (ldl-c), high-density l-c (hdl-c), and very-low-density l-c (vldl-c)). |
2022-05-20 |
2023-08-13 |
rat |
| Xuebing Chen, Jingshen Zhuang, Qianling Chen, Luyao Xu, Xia Yue, Dongfang Qia. Chronic exposure to polyvinyl chloride microplastics induces liver injury and gut microbiota dysbiosis based on the integration of liver transcriptome profiles and full-length 16S rRNA sequencing data. The Science of the total environment. 2022-05-19. PMID:35588832. |
our results showed that the levels of serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) in the mice exposed to pvc mps were markedly higher than those in the control group, implying hepatic injury, as evidenced by hepatic histopathological changes. |
2022-05-19 |
2023-08-13 |
mouse |
| Takumi Noda, Ryuji Kato, Yasuyuki Ozato, Yuka Kawai, Masato Yamamoto, Yuya Kagawa, Misa Azuma, Kojiro Yamamoto, Mika Kusanagi, Kiyoaki Uryu, Hiromasa Harada, Yoshio Ijiri, Tetsuya Hayashi, Kazuhiko Tanak. Decreased plasma acetaminophen glucuronide/acetaminophen concentration ratio warns the onset of acetaminophen-induced liver injury. Biopharmaceutics & drug disposition. 2022-05-18. PMID:35508086. |
in a clinical study, we had a case in which aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels increased in a patient with a low ratio of apap glucuronide concentration (ap-g)/apap plasma concentration. |
2022-05-18 |
2023-08-16 |
rat |
| Qingqing Liu, Haixia Tian, Hao Yang, Xing Kang, Haixia Liu, Xiaodan Yang, Xuguang Luo, Weiping Fa. [Metformin activates AMPK to alleviate acute fulminant hepatitis induced by concanavalin A in mice]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 38. issue 4. 2022-05-18. PMID:35583058. |
the serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast) and total bilirubin (tb) were detected; the pathological changes of mouse liver tissue were observed with he staining; the macrophage infiltration in liver tissue was detected with immunohistochemistry. |
2022-05-18 |
2023-08-13 |
mouse |
| Dhruba Das, Kalyan Sarma, Chethan Gollahalli Eregowda, Parimal Roychoudhury, Justus Babykutty Rajesh, Parthasarathi Behera, Hridayesh Prasad, Hniang Lalrinkima, Fatema Aktar, Nikitasha Bora, Champak Deka, Neeraj Thakur, Thingujam Chaa Tolenkhomb. Naturally occurring Anaplasma marginale infection in cattle: Molecular prevalence and associated risk factors, haemato-biochemical alterations, oxidant/antioxidant status and serum trace mineral levels. Microbial pathogenesis. 2022-05-17. PMID:35580762. |
the mean values of total erythrocyte count (tec), haemoglobin (hb), packed cell volume (pcv), total platelet count, total protein, albumin, superoxide dismutase (sod), glutathione (gsh), total antioxidant capacity (tac), copper (cu) and zinc (zn) were significantly (p < 0.05) lower, whereas the mean values of mean corpuscular volume (mcv), aspartate aminotransferase (ast), total bilirubin, indirect bilirubin, blood urea nitrogen (bun), creatinine and lipid hydroperoxide (lpo) were significantly (p < 0.05) higher in cattle infected with a. marginale. |
2022-05-17 |
2023-08-13 |
cattle |
| Supat Chupradit, Dmitry Bokov, Mohammad Yassin Zamanian, Mahsa Heidari, Elham Hakimizade. Hepatoprotective and therapeutic effects of resveratrol: A focus on anti-inflammatory and antioxidative activities. Fundamental & clinical pharmacology. vol 36. issue 3. 2022-05-16. PMID:34935193. |
additionally, it reduces oxidative stress in hepatic tissue by markedly reducing malondialdehyde (mda) and nitric oxide (no) contents and significantly increasing the levels of catalase (cat), superoxide dismutase (sod), and reduced hepatic glutathione (gsh), in addition to aspartate aminotransferase (ast) and alanine aminotransferase (alt), against toxic chemicals like cc14, as2o3, and tta. |
2022-05-16 |
2023-08-16 |
cat |
| Denise Battaglini, Miquéias Lopes-Pacheco, Hugo C Castro-Faria-Neto, Paolo Pelosi, Patricia R M Rocc. Laboratory Biomarkers for Diagnosis and Prognosis in COVID-19. Frontiers in immunology. vol 13. 2022-05-16. PMID:35572561. |
the most used biomarkers in covid-19 include several proinflammatory cytokines, neuron-specific enolase (nse), lactate dehydrogenase (ldh), aspartate transaminase (ast), neutrophil count, neutrophils-to-lymphocytes ratio, troponins, creatine kinase (mb), myoglobin, d-dimer, brain natriuretic peptide (bnp), and its n-terminal pro-hormone (nt-probnp). |
2022-05-16 |
2023-08-13 |
Not clear |
| Simiao Pan, Xiaobo Yan, Xiaohui Dong, Tao Li, Xiangxiang Suo, Beiping Tan, Shuang Zhang, Zhihao Li, Yuanzhi Yang, Haitao Zhan. The positive effects of dietary inositol on juvenile hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ E. lanceolatu) fed high-lipid diets: Growth performance, antioxidant capacity and immunity. Fish & shellfish immunology. 2022-05-16. PMID:35577318. |
in the serum, superoxide dismutase (sod) of the j4 group became significantly active compared with that of the control group (p < 0.05), while aspartate transaminase (ast), alanine transaminase (alt) and alkaline phosphatase (akp) activities in the inositol-treated groups showed distinctly decreased compared with those of the control group (p < 0.05). |
2022-05-16 |
2023-08-13 |
cat |
| Rolf Teschke, Nahum Méndez-Sánchez, Axel Eickhof. Liver Injury in COVID-19 Patients with Drugs as Causatives: A Systematic Review of 996 DILI Cases Published 2020/2021 Based on RUCAM as Causality Assessment Method. International journal of molecular sciences. vol 23. issue 9. 2022-05-14. PMID:35563242. |
a total of 6/200 reports with initially suspected 996 dili cases in covid-19 patients and using all rucam-based dili cases allowed for a clear description of clinical features of rucam-based dili cases among covid-19 patients: (1) the updated rucam published in 2016 was equally often used as the original rucam of 1993, with both identifying dili and other liver diseases as confounders; (2) rucam also worked well in patients treated with up to 18 drugs and provided for most dili cases a probable or highly probable causality level for drugs; (3) dili was preferentially caused by antiviral drugs given empirically due to their known therapeutic efficacy in other virus infections; (4) hepatocellular injury was more often reported than cholestatic or mixed injury; (5) maximum lt values were found for alanine aminotransferase (alt) 1.541 u/l and aspartate aminotransferase (ast) 1.076 u/l; (6) the alt/ast ratio was variable and ranged from 0.4 to 1.4; (7) the mean or median age of the covid-19 patients with dili ranged from 54.3 to 56 years; (8) the ratio of males to females was 1.8-3.4:1; (9) outcome was favorable for most patients, likely due to careful selection of the drugs and quick cessation of drug treatment with emerging dili, but it was fatal in 19 patients; (10) countries reporting rucam-based dili cases in covid-19 patients included china, india, japan, montenegro, and spain; (11) robust estimation of the percentage contribution of rucam-based dili for the increased lts in covid-19 patients is outside of the current scope. |
2022-05-14 |
2023-08-13 |
Not clear |
| Aneta Strachecka, Karolina Kuszewska, Krzysztof Olszewski, Patrycja Skowronek, Maciej Grzybek, Marcin Grabowski, Jerzy Paleolog, Michał Woyciechowsk. Activities of Antioxidant and Proteolytic Systems and Biomarkers in the Fat Body and Hemolymph of Young Animals : an open access journal from MDPI. vol 12. issue 9. 2022-05-14. PMID:35565549. |
we determined the activities of acidic, neutral, and alkaline proteases and their inhibitors, as well as superoxide dismutase (sod), catalase (cat), aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), and the level of total antioxidant potential (tac). |
2022-05-14 |
2023-08-13 |
cat |
| Juan-Fen Mo, Jia-Yuan Wu, Li Zheng, Ya-Wei Yu, Tian-Xin Zhang, Li Guo, Yi Ba. Therapeutic efficacy of polydatin for nonalcoholic fatty liver disease RSC advances. vol 8. issue 54. 2022-05-13. PMID:35548751. |
pd also downregulated the serum levels of triglyceride (tg), low density lipoprotein (ldl), aspartate aminotransferase (ast) and alanine aminotransferase (alt), and upregulated high density lipoprotein (hdl). |
2022-05-13 |
2023-08-13 |
mouse |
| Baohuan Lian, Lijun Cai, Zhaoqiang Zhang, Fen Lin, Zongxi Li, Xiao-Kun Zhang, Fuquan Jian. The anti-inflammatory effect of Pien Tze Huang in non-alcoholic fatty liver disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 151. 2022-05-13. PMID:35550529. |
our results showed that pth could exert hepatoprotective effects by improving liver weight and steatosis and reducing the fibrosis and serum levels of alanine transaminase (alt) and aspartate transaminase (ast) in both animal models. |
2022-05-13 |
2023-08-13 |
mouse |