| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jian-Nan Zhang, Yang Gao, Xin-Tong Wang, Na-Na Li, Xue Du, Yu-Jia Tang, Qi-Qi Lai, Peng-Fei Chen, Chuang-Shi Yue, Ji-Han Wu, Kai Kang, Ming-Yan Zha. Lymphocyte-C-reactive protein ratio can differentiate disease severity of COVID-19 patients and serve as an assistant screening tool for hospital and ICU admission. Frontiers in immunology. vol 13. 2022-10-17. PMID:36248811. |
demographic and clinical data including gender, age, comorbidities, severity of covid-19, white blood cell count (wbc), neutrophil proportion (neut%), lymphocyte count (lymph), lymphocyte percentage (lym%), red blood cell distribution width (rdw), platelet (plt), c-reactive protein (crp), alanine aminotransferase (alt), aspartate aminotransferase (ast), serum creatinine (scr), albumin (alb), total bilirubin (tb), direct bilirubin (dbil), indirect bilirubin (ibil), and d-dimer were obtained and collated from medical records at admission, from which sequential organ failure assessment (sofa) score and lcr were calculated, and all the above indicators were compared among the groups. |
2022-10-17 |
2023-08-14 |
Not clear |
| Fen Zhang, Linxiao Fan, Qiuhong Liu, Shima Tang, Sainan Zhang, Lanlan Xiao, Lingjian Zhang, Qian Li, Nueraili Maihemuti, Lanjuan L. Comprehensive immune cell analysis of human menstrual-blood-derived stem cells therapy to concanavalin A hepatitis. Frontiers in immunology. vol 13. 2022-10-17. PMID:36248904. |
the serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels and h&e staining depicted that menscs treatment could significantly alleviate cona-induced hepatitis. |
2022-10-17 |
2023-08-14 |
mouse |
| Thomas Minor, Charlotte von Horn, Hristo Zlatev, Fuat Saner, Melanie Grawe, Bastian Lüer, Eva-Maria Huessler, Nils Kuklik, Andreas Pau. Controlled oxygenated rewarming as novel end-ischemic therapy for cold stored liver grafts. A randomized controlled trial. Clinical and translational science. 2022-10-17. PMID:36251938. |
primary outcome mean peak aspartate aminotransferase (ast) was 1371 u/l (sd 2871) after scs versus 767 u/l (sd 1157) after cor (p = 0.273). |
2022-10-17 |
2023-08-14 |
Not clear |
| Jinjin Li, Jie Li, Hongbo Fang, Hang Yang, Tianchun Wu, Xiaoyi Shi, Chun Pan. Isolongifolene alleviates liver ischemia/reperfusion injury by regulating AMPK-PGC1α signaling pathway-mediated inflammation, apoptosis, and oxidative stress. International immunopharmacology. vol 113. issue Pt A. 2022-10-17. PMID:36252482. |
the results showed that iso reduced serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels, liver necrosis, inflammatory factors il-1β, il-6, mcp-1, and tnf-α expression, mpo |
2022-10-17 |
2023-08-14 |
mouse |
| Muhammad Imran Qayyum, Sami Ullah, Umer Rashid, Abdul Sadiq, Obaidullah, Mater H Mahnashi, Osama M Alshehri, Mohammed M Jalal, Khalid J Alzahrani, Ibrahim F Halawan. Synthesis, Molecular Docking, and Preclinical Evaluation of a New Succinimide Derivative for Cardioprotective, Hepatoprotective and Lipid-Lowering Effects. Molecules (Basel, Switzerland). vol 27. issue 19. 2022-10-14. PMID:36234730. |
toxicity induced by 5-fu was manifested by increases in the serum creatinine kinase myocardial band (ck-mb), troponin i (ctni) and lactate dehydrogenase (ldh), lipid profile, and selected liver enzymes, including alp (alkaline phosphatase), alt (alanine transaminase), ast (aspartate aminotransferase), bt (bilirubin total), and bd (direct bilirubin). |
2022-10-14 |
2023-08-14 |
human |
| Johnafaye Mariano, George A MacLare. A Case of Rhabdomyolysis in a Young, Morbidly Obese, Asthmatic Woman With COVID-19. Cureus. vol 14. issue 9. 2022-10-14. PMID:36237756. |
alanine aminotransferase (alt), aspartate aminotransferase (ast), and creatine kinase (ck) levels were noted to be elevated. |
2022-10-14 |
2023-08-14 |
Not clear |
| b' Aleksandar Antonijevi\\xc4\\x87, Emilija Stojanovi\\xc4\\x87, Aleksandar Jevti\\xc4\\x87, Vladimir \\xc5\\xbdivkovi\\xc4\\x87, Sergey Bolevich, Vladimir Jakovljevi\\xc4\\x8. The effect of a 6-month walking program on biochemical parameters in sedentary adults with type 2 diabetes mellitus. Nagoya journal of medical science. vol 84. issue 3. 2022-10-14. PMID:36237879.' |
plasma glucose, triglyceride, total cholesterol, low-density lipoprotein cholesterol (ldl), high-density lipoprotein cholesterol (hdl), aspartate aminotransferase (ast), alanine aminotransferase (alt), gamma-glutamyl transferase, urea, creatinine, uric acid, c-reactive protein (crp), and erythrocyte sedimentation rate were measured. |
2022-10-14 |
2023-08-14 |
Not clear |
| Manman Duan, Xuanjun Guo, Xiangguang Chen, Mengyu Guo, Mengna Zhang, Hao Xu, Chengju Wang, Yang Yan. Transcriptome analysis reveals hepatotoxicity in zebrafish induced by cyhalofop‑butyl. Aquatic toxicology (Amsterdam, Netherlands). vol 252. 2022-10-14. PMID:36240591. |
meanwhile, the activities of enzymes related to liver function were significantly increased by 0.2 mg/l cyhalofop‑butyl and higher, such as alanine transaminase (alt) and aspartate transaminase (ast). |
2022-10-14 |
2023-08-14 |
zebrafish |
| Mahsa Rastegar Moghaddam Poorbagher, Ehsan Karimi, Ehsan Oskoueia. Hepatoprotective effect of nanoniosome loaded Myristica fragrans phenolic compounds in mice-induced hepatotoxicity. Journal of cellular and molecular medicine. 2022-10-13. PMID:36226354. |
in addition, the blood levels of triglyceride (tg), cholesterol (chol), liver enzymes (aspartate aminotransferase (ast), alanine transaminase (alt), alkaline phosphatase (alp)) and total bilirubin were significantly (p ≤ 0.05) decreased. |
2022-10-13 |
2023-08-14 |
mouse |
| Reham Hassan, Daniela González, Zaynab Hobloss, Lisa Brackhagen, Maiju Myllys, Adrian Friebel, Abdel-Latif Seddek, Rosemarie Marchan, Benedikt Cramer, Hans-Ulrich Humpf, Stefan Hoehme, Gisela H Degen, Jan G Hengstler, Ahmed Ghalla. Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A. Archives of toxicology. 2022-10-13. PMID:36227364. |
the blood biomarkers of liver damage, alanine transaminase (alt) and aspartate transaminase (ast) both increased > 21- and 30-fold, respectively, when ota was administered to abt pre-treated mice compared to the effect of ota alone. |
2022-10-13 |
2023-08-14 |
mouse |
| Tung Huynh, Stephanie Ma, Ke-Qin H. HCV direct acting antiviral treatment leads to highly durable rates of ALT and AST lower than 30/19 criteria and improved APRI and FIB-4 scores. Hepatology communications. 2022-10-12. PMID:36221305. |
direct acting antiviral treatment (daa) has been the standard of care for hepatitis c virus (hcv) infection, but its long-term benefits in alanine aminotransferase (alt) and aspartate aminotransferase (ast) improvement and hepatic fibrosis assessed by aspartate aminotransferase-to-platelet ratio index (apri) and fibrosis-4 index (fib-4) scores remain unknown. |
2022-10-12 |
2023-08-14 |
Not clear |
| Hongkun Xue, Yu Wang, Hongwei Xiang, Qi Song, Guowei Zhang, Jianguo Wang, Shaoqin G. Exploring the Protective Effects and Mechanism of Huaji Jianpi Decoction against Nonalcoholic Fatty Liver Disease by Network Pharmacology and Experimental Validation. Evidence-based complementary and alternative medicine : eCAM. vol 2022. 2022-10-06. PMID:36199550. |
compared with the model group, the liver wet weight, liver/body ratio, the levels of total cholesterol (tc), triglyceride (tg), aspartate aminotransferase (ast), alanine aminotransferase (alt), and high-density lipoprotein (hdl) in serum in the hjjpd low-dose (17.52 g/kg·d), medium-dose (35.04 g/kg·d), and high-dose (70.07 g/kg·d) groups significantly decreased ( |
2022-10-06 |
2023-08-14 |
mouse |
| Meiling Zuo, Yue Shang, Ye Guo, Yuxuan Sun, Gaoqi Xu, Jingtao Chen, Liqin Zh. Population Pharmacokinetics of Tacrolimus in Umbilical Cord Blood Transplant Pediatrics. Journal of clinical pharmacology. 2022-10-05. PMID:36196568. |
the impact of demographic features, biological characteristics, and concomitant medications, including sex, age, body weight, postoperative day, white blood cell (wbc), red blood cell (rbc), hemoglobin (hb), platelet (plt), hematocrit (hct), urea nitrogen (bun), creatinine (cr), aspartate transaminase (ast), alanine transaminase (alt), total bilirubin (tbil), albumin (alb), and total protein (tp) were investigated. |
2022-10-05 |
2023-08-14 |
Not clear |
| Anjali Pitamberwale, Tariq Mahmood, Azmat Kamal Ansari, Shabana Andleeb Ansari, Kirti Limgaokar, Lalit Singh, Geeta Kark. Biochemical Parameters as Prognostic Markers in Severely Ill COVID-19 Patients. Cureus. vol 14. issue 8. 2022-10-03. PMID:36185918. |
results of the 178 severely ill covid-19 patients enrolled in the study, 86 were controls and 92 were cases (52% mortality). serum urea (p<0.0001), creatinine (p=0.0019), aspartate transaminase (ast) (p=0.0104), lactate dehydrogenase (ldh) (p=0.0001), procalcitonin (pct) (p=0.0344), and interleukin 6 (il-6) (p=0.0311) levels were significantly higher (p<0.05), while total protein (p=0.0086), albumin (p<0.0001), and indirect bilirubin (p=0.0147) levels were significantly lower (p<0.05) in cases as compared to controls. |
2022-10-03 |
2023-08-14 |
Not clear |
| Yongchao Gao, Chao Sun, Ting Gao, Zhiyong Liu, Zhao Yang, Hui Deng, Peng Fan, Junhong Ga. Taurine ameliorates volatile organic compounds-induced cognitive impairment in young rats Frontiers in veterinary science. vol 9. 2022-10-03. PMID:36187803. |
moreover, taurine decreased malondialdehyde (mda), γ-aminobutyric acid (gaba), aspartate aminotransferase (ast), alanine aminotransferase (alt), urea, creatinine (crea) and injury biomarker level, enhanced superoxide dismutase (sod), reduced glutathione (gsh) and glutamic acid (glu) activities, up-regulated the protein expression of brain derived neurotrophic factor (bdnf) and n-methyl-d-aspartate receptor 1 (nmdar1) in model rats, and in most of cases 1% but not 0.5%, ameliorated the defects induced by vocs. |
2022-10-03 |
2023-08-14 |
rat |
| Bo Zhang, Zeben Wang, Chenxuan Huang, Dehe Wang, Dongmei Chang, Xiaowei Shi, Yifan Chen, Hui Che. Positive effects of Mulberry leaf extract on egg quality, lipid metabolism, serum biochemistry, and antioxidant indices of laying hens. Frontiers in veterinary science. vol 9. 2022-10-03. PMID:36187805. |
hens were fed a basal diet supplemented with 0 (control diet), 0.4, 0.8, or 1.2% mle for 56 d. results showed that the addition of 0.4-1.2% mle to the diet improved aspartate transaminase (ast) activity in the serum of laying hens, reduced low-density lipoprotein (ldl-c) content in the serum, and significantly decreased yolk triglyceride (tg) and total cholesterol (tc) contents ( |
2022-10-03 |
2023-08-14 |
Not clear |
| Xenophon Theodoridis, Georgios Kalopitas, Andreas Vadarlis, Dimitra Rafailia Bakaloudi, Νikolaos Gkiourtzis, Georgios Dionysopoulos, Evangelia Karanika, Eirini Tsekitsidi, Michail Chourdaki. Comparative efficacy of different treatment modalities in the management of pediatric non-alcoholic fatty liver disease: A systematic review and network meta-analysis. Pharmacology & therapeutics. 2022-10-02. PMID:36183848. |
secondary outcomes were changes in aspartate aminotransferase (ast), lipidemic and other biochemical parameters concentrations and body mass index (bmi) values. |
2022-10-02 |
2023-08-14 |
human |
| Changqing Zhang, Chenqinyao Li, Kechun Liu, Yun Zhan. Characterization of zearalenone-induced hepatotoxicity and its mechanisms by transcriptomics in zebrafish model. Chemosphere. 2022-10-01. PMID:36181844. |
first, we found zearalenone exposure can specifically cause liver injury, as evidenced by reduced liver size, decreased liver-specific fluorescence, increased aspartate aminotransferase (ast) activity, delayed yolk sac absorption and lipid accumulation. |
2022-10-01 |
2023-08-14 |
human |
| Yucong Wang, Tao Xu, Hui Zhao, Chunxiao Gu, Zhongzheng L. Effect of taurine in muscle damage markers and inflammatory cytokines in running exercise. Frontiers in physiology. vol 13. 2022-09-30. PMID:36176774. |
we assessed serum creatine kinase (ck), ck isoenzyme, lactate dehydrogenase (ldh), aspartate transaminase (ast), tumor necrosis factor-alpha (tnf-alpha), and interleukin-6 (il-6). |
2022-09-30 |
2023-08-14 |
human |
| Chen Zhu, Xinwei Cheng, Ping Gao, Qianyan Gao, Ximin Wang, Dong Liu, Xiuhua Ren, Chengliang Zhan. Model establishment and microarray analysis of mice with oxaliplatin‑induced hepatic sinusoidal obstruction syndrome. Molecular medicine reports. vol 26. issue 5. 2022-09-30. PMID:36177905. |
the serum levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast) were determined. |
2022-09-30 |
2023-08-14 |
mouse |