| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Gharehbeglou, S Yazdani, K White, M R Haeri, N Masoumzade. Atorvastatin Rapidly Reduces Hepatitis B Viral Load in Combination with Tenofovir: A Prospective Clinical Trial. The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale. vol 2022. 2022-07-25. PMID:35873362. |
serum aspartate aminotransferase (ast), alanine aminotransferase (alt), and hbv dna copy numbers were measured at the beginning of the treatment and 1, 3, 6, 9, 12 months later. |
2022-07-25 |
2023-08-14 |
Not clear |
| Omotayo B Ilesanmi, Esther F Adeogun, Temitope T Odewale, Bruno Chiker. Lead exposure-induced changes in hematology and biomarkers of hepatic injury: protective role of TrévoTM supplement. Environmental analysis, health and toxicology. vol 37. issue 2. 2022-07-25. PMID:35878915. |
animals were sacrificed 24 h after the last administration and blood were collected via cardiac puncture and processed for hematological parameters and assessment of alanine aminotransferase (alt), aspartate aminotransferase (ast), and albumin (alb). |
2022-07-25 |
2023-08-14 |
human |
| Ying Lan, Chi Wang, Cheng Zhang, Pengju Li, Jinding Zhang, Hong Ji, Haibo Y. Dietary sea buckthorn polysaccharide reduced lipid accumulation, alleviated inflammation and oxidative stress, and normalized imbalance of intestinal microbiota that was induced by high-fat diet in zebrafish Danio rerio. Fish physiology and biochemistry. 2022-07-25. PMID:35879492. |
results showed that adding 2 and 4 g/kg of sp in the hfd significantly improved the survival rate of zebrafish; reduced the levels of serum triglyceride (tg), total cholesterol (tc), aspartate aminotransferase (ast), and alanine transaminase (alt); and alleviated the lipid accumulation in the liver of zebrafish. |
2022-07-25 |
2023-08-14 |
zebrafish |
| Wenjie Zhu, Meizhu Yan, Haibin Cao, Jun Zhou, Zhongqing X. Effects of Clostridium butyricum Capsules Combined with Rosuvastatin on Intestinal Flora, Lipid Metabolism, Liver Function and Inflammation in NAFLD Patients. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 2. 2022-07-23. PMID:35869734. |
moreover, the observation group had remarkably lower levels of total cholesterol (tc), triglyceride (tg), free fatty acids (ffa), total bilirubin (tbil), direct bilirubin (dbil), alanine aminotransferase (alt), aspartate aminotransferase (ast), procollagen iii peptide (piiip), collagen-iv (c-iv), hyaluronicacid (ha) and laminin (ln) as well as lower levels of tumor necrosis factor-alpha (tnf-α), catabolite activator protein (cap) and interleukin-6 (il-6) in serum than the control group (p<0.05). |
2022-07-23 |
2023-08-14 |
human |
| Zhicheng Li, Biao Jiang, Zhihong Zhong, Jizhen Cao, Han Li, Chenxi Wang, Anxing L. Skin transcriptomic analysis and immune-related gene expression of golden pompano (Trachinotus ovatus) after Amyloodinium ocellatum infection. Fish & shellfish immunology. 2022-07-23. PMID:35870749. |
in addition, the serum of the primary infection group had significantly higher concentrations of triglyceride (tg), higher alanine transaminase (alt), aspartate transaminase (ast), and lactate dehydrogenase (ldh) activities than the control group. |
2022-07-23 |
2023-08-14 |
Not clear |
| Cai Zhang, Sudan Meng, Qi Shao, Xueying Wang, Chenxu Li, Wenbin Chen, Yuanxiao Li, Shucheng Huang, Yanbo M. Protective effects of monoammonium glycyrrhizinate on fatty deposit degeneration induced in primary calf hepatocytes by sodium oleate administration in vitro. Research in veterinary science. vol 150. 2022-07-22. PMID:35868152. |
to evaluate the effect of mag on fat-induced degradation of primary hepatocytes, we evaluated lipid deposition, cell viability, apoptosis rate, alanine aminotransferase (alt) and aspartate aminotransferase (ast) activity in the culture supernatant, and expression of oxidant and antioxidant enzymes (ldh, mda, gsh, and cat), as well as the expression of lipid metabolism-related genes (pparα, srebp-1c, chrebp, cpt1, cpt2, and mtp) and apoptosis-related genes (cyt-c, caspase 9, caspase 8, caspase 3, bax, and bcl-2). |
2022-07-22 |
2023-08-14 |
cat |
| Toussaint Rouamba, Paul Sondo, Isidore W Yerbanga, Adelaide Compaore, Maminata Traore-Coulibaly, Franck S Hien, Nassirou A Diande, Innocent Valea, Marc Christian Tahita, Rita Baiden, Fred Binka, Halidou Tint. Prospective observational study to evaluate the clinical and biological safety profile of pyronaridine-artesunate in a rural health district in Burkina Faso. Pharmacology research & perspectives. vol 10. issue 4. 2022-07-20. PMID:35855566. |
additionally, the study focused on aes of special interest (aesi), namely clinical signs related to hepatotoxicity and increased alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2022-07-20 |
2023-08-14 |
Not clear |
| Souvik Dhara, H P Gupta, Sunil Kumar, R K Sharma, Swati Thaku. Effects of Heterologous Bovine Seminal Plasma-Supplemented Egg Yolk-Based Extender on Cryosurvivability of Pantja Buck Semen. Biopreservation and biobanking. 2022-07-20. PMID:35856825. |
alanine aminotransferase (alt), aspartate aminotransferase (ast), malondialdehyde (mda) concentration, and glutathione peroxidase (gsh-px) activity were measured at post-thaw. |
2022-07-20 |
2023-08-14 |
cattle |
| Yucheng Wu, Fang Li. Aspartate aminotransferase to alanine aminotransferase ratio and the risk of diabetic nephropathy progression in patients with type 2 diabetes mellitus: A biopsy-based study. Journal of diabetes and its complications. 2022-07-19. PMID:35853763. |
to study the relationship between baseline serum aspartate aminotransferase (ast) to alanine aminotransferase (alt) ratio (aar) in both clinicopathological features and renal outcome among type 2 diabetes mellitus (t2dm) patients with biopsy-confirmed diabetic nephropathy (dn). |
2022-07-19 |
2023-08-14 |
Not clear |
| Anjali Athanerey, Neha Rani Verma, Piyush Bhargava, Dnyanesh Amle, P K Patra, Awanish Kuma. Biochemical aspects of effects of mesenchymal stem cell treatment in chronic wounds progressive healing. Cell and tissue banking. 2022-07-18. PMID:35849224. |
various biochemical parameters like random blood glucose, serum urea, serum creatinine, bilirubin (total and direct), aspartate aminotransferase (ast), alanine aminotransferase (alt), total protein, albumin levels, and association of other factors/conditions such as age, sex, addiction of drug/alcohol were also evaluated/compared with complete and without complete healing. |
2022-07-18 |
2023-08-14 |
Not clear |
| Miao Weng, Wencong Zhang, Zhou Zhang, Yuhang Tang, Wencong Lai, Zhijie Dan, Yongtao Liu, Jichang Zheng, Shengnan Gao, Kangsen Mai, Qinghui A. Effects of dietary lysolecithin on growth performance, serum biochemical indexes, antioxidant capacity, lipid metabolism and inflammation-related genes expression of juvenile large yellow croaker (Larimichthys crocea). Fish & shellfish immunology. 2022-07-17. PMID:35843522. |
meanwhile, serum aspartate transaminase (ast) and alanine transaminase (alt) activities in fish fed diets with lysolecithin were remarkably lower than those in the control diet (p < 0.05). |
2022-07-17 |
2023-08-14 |
Not clear |
| Yong Zheng, Hongning Shi, Yahao Zhou, Ayong Wang, Dufu Kang, Limin Kan. Effects of endoplasmic reticulum stress, liver function, insulin resistance and vascular endothelial function in patients with nonalcoholic fatty liver disease. Cellular and molecular biology (Noisy-le-Grand, France). vol 67. issue 5. 2022-07-12. PMID:35818251. |
the expression level of glucose-regulated protein 94 (grp94) and biochemical indicators such as alanine aminotransferase (alt), free fatty acids (ffa), triglycerides (tg), gamma-glutamyl transferase (ggt), aspartate aminotransferase (ast), fasting blood glucose (fbg), and fasting insulin (fins) were measured. |
2022-07-12 |
2023-08-14 |
Not clear |
| Zhanwei Fan, Jianjiang Dong, Yindong Mu, Xian Li. Nesfatin-1 protects against diabetic cardiomyopathy in the streptozotocin-induced diabetic mouse model via the p38-MAPK pathway. Bioengineered. vol 13. issue 6. 2022-07-12. PMID:35818327. |
nesfatin-1 ameliorated the diabetes-related myocardial hypertrophy and heart dysfunction, as revealed by the reduced hypertrophy index, heart rate, mean arterial pressure (map), creatine kinase (ck)-mb, and aspartate aminotransferase (ast) levels. |
2022-07-12 |
2023-08-14 |
mouse |
| Milena D Scheidegger, Vinzenz Gerber, Gaudenz Dolf, Dominik Burger, Shannon Axiak Flammer, Alessandra Ramseye. Quantitative gait analysis before and after a cross-country test in a population of elite eventing horses. Journal of equine veterinary science. 2022-07-12. PMID:35820497. |
the effects of la concentration immediately after completion of the cross-country course and of serum levels of creatine kinase (ck) and aspartate amino-transferase (ast) four hours post-exercise on gait asymmetry parameters were tested with linear models. |
2022-07-12 |
2023-08-14 |
human |
| Kendal Erdem Duman, Abdulahad Dogan, Burak Kaptane. Ameliorative role of Cyanus depressus (M.Bieb.) Soják plant extract against diabetes-associated oxidative-stress-induced liver, kidney, and pancreas damage in rats. Journal of food biochemistry. 2022-07-08. PMID:35802765. |
weekly blood glucose, serum glucose, aspartate aminotransferase (ast), alanine aminotransferase (alt), lactate dehydrogenase (ldh) and urea, malondialdehyde (mda) (liver and pancreas), and blood glycosylated hemoglobin % (hba1c %) were significantly decreased, whereas finally live body weights (lbws), reduced glutathione (gsh), glutathione s-transferase (gst) and catalase (cat) (pancreas), and pancreatic islet diameter and area were increased significantly in the cd-treated diabetic group. |
2022-07-08 |
2023-08-14 |
rat |
| Alexandre Raynor, Anna Soavelomandroso, Tiphaine Robert-Mercier, Dominique Valla, Katell Peoc'h, Célia Raulet-Bussia. Usual transaminase values: should they be reviewed and adjusted? Annales de biologie clinique. vol 80. issue 3. 2022-07-07. PMID:35796475. |
alanine (alt) and aspartate aminotransferases (ast) are intracellular enzymes involved in the metabolism of amino acids. |
2022-07-07 |
2023-08-14 |
Not clear |
| Chih-Min Yang, Mei-Yin Chien, Li-Yu Wang, Cheng-Hung Chuang, Chao-Hsiang Che. Goji Ferment Ameliorated Acetaminophen-Induced Liver Injury in vitro and in vivo. Probiotics and antimicrobial proteins. 2022-07-07. PMID:35796949. |
lpgf containing all combinations of lab strains, except for koda-2, significantly restored apap-reduced cell viability and improved apap-increased cellular levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2022-07-07 |
2023-08-14 |
mouse |
| Elsayed T Helmy, Mona A Ali, Mohamed A Ayyad, H G Mohamedbakr, Rajender S Varma, Jia Hong Pa. Molluscicidal and biochemical effects of green-synthesized F-doped ZnO nanoparticles against land snail Monacha cartusiana under laboratory and field conditions. Environmental pollution (Barking, Essex : 1987). 2022-07-06. PMID:35792294. |
the effect of lethal concentrations, that kills 50% of exposed snails (lc50) value of the treatments, is examined on the activity of alkaline phosphatase (alp), aspartate aminotransferase (ast), alanine aminotransferase (alt), enzymes, total protein (tp), total lipids (tl) and cholesterol level of snails, including the histopathological evaluation of the digestive gland and foot of m. cartusiana. |
2022-07-06 |
2023-08-14 |
Not clear |
| Baran Seven, Kültiğin, Çavuşoğlu, Emine Yalçin, Ali Aca. Investigation of cypermethrin toxicity in Swiss albino mice with physiological, genetic and biochemical approaches. Scientific reports. vol 12. issue 1. 2022-07-06. PMID:35794216. |
for this aim, body and organ weights, aspartate aminotransferase (ast), alanine aminotransferase (alt), malondialdehyde (mda), glutathione (gsh), blood urea nitrogen (bun) and creatinine levels, mitotic index (mi), dna fragmentation, frequency of micronucleus (mn) and chromosomal aberrations (cas) were used as indicators of toxicity. |
2022-07-06 |
2023-08-14 |
mouse |
| Qingyu Zhao, Zhenyu Liu, Yiqing Zhu, Han Wang, Zijian Dai, Xuehao Yang, Xin Ren, Yong Xue, Qun She. Cooked Adzuki Bean Reduces High-Fat Diet-Induced Body Weight Gain, Ameliorates Inflammation, and Modulates Intestinal Homeostasis in Mice. Frontiers in nutrition. vol 9. 2022-07-05. PMID:35782919. |
cooked adzuki bean significantly inhibited weight gain and hepatic steatosis, reduced high levels of serum triacylglycerol (tg), alanine aminotransferase (alt), and aspartate aminotransferase (ast), and alleviated systemic inflammation and metabolic endotoxemia in mice fed a hfd. |
2022-07-05 |
2023-08-14 |
mouse |