| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qian-Nan Li, Jin-Feng Shang, Ting-Yue Jiang, Lei Bi, Jia-Kang Jiao, Ying-Hui Lu, Qi Song, Shabuer-Jiang Lizha, Xin Li. [Exploration of mechanism of "simultaneous treatment of brain and heart" of Naoxintong Capsules based on Toll-like receptor signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 15. 2022-09-01. PMID:36046901. |
at the same time, the reduction in apoptosis rate of cardiocytes and the content of serum aspartate aminotransferase(ast), alanine aminotransferase(alt), creatine kinase(ck), and lactate dehydrogenase(ldh) were decreased in the nxt group.systems pharmacological results and previous research showed that tlr signaling pathway played an important role in immune inflammatory response.the study of tlr signaling pathway and related proteins is helpful to elucidate the mechanism of "simultaneous treatment of the brain and the heart". |
2022-09-01 |
2023-08-14 |
rat |
| Guo-Qing Li, Ting Shu, Yuan-Yuan Chai, Xin Huang, Zhen-Zhou Jiang, Lu-Yong Zhan. [Determination of concentrations and toxicokinetics of triptolide in plasma and liver of mice by UHPLC-MS/MS]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 15. 2022-09-01. PMID:36046909. |
furthermore, the blood biochemical indexes, including alkaline phosphatase(alp), alanine aminotransferase(alt), aspartate aminotransferase(ast), and total bile acid(tba), were determined. |
2022-09-01 |
2023-08-14 |
mouse |
| Amel Jebara, Asma Beltifa, Guissepa Di Bella, Lotfi Mabrouk, Hedi Ben Mansou. Endocrine-disruptor endpoints in the ovary and thyroid of adult female rats exposed to realistic doses of di-(2-ethylhexyl) phthalate. Journal of water and health. vol 20. issue 8. 2022-08-31. PMID:36044193. |
we also observed cellular damage, particularly in the liver cells, and a significant increase in biochemical parameters such as alanine aminotransferase (alt) and aspartate aminotransferase (ast) compared to the control group. |
2022-08-31 |
2023-08-14 |
human |
| Vahideh Jalili, Zohreh Poorahmadi, Naeemeh Hasanpour Ardekanizadeh, Maryam Gholamalizadeh, Marjan Ajami, Anahita Houshiarrad, Azadeh Hajipour, Fatemeh Shafie, Atiyeh Alizadeh, Zohreh Mokhtari, Hanieh Shafaei, Mina Esmaeili, Saeid Doae. The association between obesity with serum levels of liver enzymes, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and gamma-glutamyl transferase in adult women. Endocrinology, diabetes & metabolism. 2022-08-30. PMID:36039792. |
this study aimed to investigate the association of obesity with serum levels of biomarkers of liver function including alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp) and gamma-glutamyl transferase (ggt) in adult women. |
2022-08-30 |
2023-08-14 |
Not clear |
| Ying Li, Wenjie Cai, Zichun Ai, Chenyu Xue, Rujing Cao, Na Don. Protective effects of sinomenine hydrochloride on lead-induced oxidative stress, inflammation, and apoptosis in mouse liver. Environmental science and pollution research international. 2022-08-29. PMID:36038687. |
sh treatment reduced the levels of liver alanine aminotransferase, aspartate aminotransferase (ast), lactate dehydrogenase (ldh), and mda in pb-treated mice, indicating that sh protected the liver from injury and oxidative stress in pb-treated mice. |
2022-08-29 |
2023-08-14 |
mouse |
| Ruobing Hao, Jun Gao, Hongwei Liu, Chenjuan Zhang, Jinpeng Huang, Jungang Fan, Jie We. Preventive Effect and Mechanism of Anthocyanins from Aronia Melanocarpa Elliot on Hepatic Fibrosis Through TGF-β/Smad Signaling Pathway. Cell biochemistry and biophysics. 2022-08-29. PMID:36038789. |
ama could effectively inhibit the expressions of aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), and total serum bilirubin (tsb), and improved the expressions of total protein (tp) and albumin (alb). |
2022-08-29 |
2023-08-14 |
Not clear |
| Liang Wang, Lingyi Zhang, Junyan Wang, Juan Li, Jie Ding, Xiaodong H. Protective Effect of Dandelion Leaf Water Extracts on APAP-Induced Liver Injury in Rats and Its Mechanism. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 5. 2022-08-27. PMID:36029509. |
the liver function lactate dehydrogenase (ldh), aspartate aminotransferase (ast) and alanine aminotransferase (alt) were detected to verify the success of the model. |
2022-08-27 |
2023-08-14 |
human |
| Bilal Sahin, Sebahattin Karabulut, Ahmet Kemal Filiz, Mustafa Özkaraca, Arzu Gezer, Hüseyin Aşkın Akpulat, Hilmi Ataseve. Galium aparineL. protects against acetaminophen-induced hepatotoxicity in rats. Chemico-biological interactions. 2022-08-27. PMID:36029804. |
ga pretreated rats exhibited a significant reduction in apap-induced liver damage, evidenced by the reduction in liver necrosis and alanine aminotransferase (alt), aspartate aminotransferase (ast), and bilirubin (bil). |
2022-08-27 |
2023-08-14 |
rat |
| Shuang Ren, Tianwen Huang, Danyan Ou, Luhuai Feng, Sisi Huang, Chaonan Zhou, Lianying G. Inhibition of TNF- Applied bionics and biomechanics. vol 2022. 2022-08-26. PMID:36016921. |
upon determining the levels of mouse myocardial creatine phosphokinase (ck), myokinase isoenzyme (ck-mb), aspartate transaminase (ast), and lactate dehydrogenase (ldh), we found that all of these levels showed apparent increases in mice treated with ptx. |
2022-08-26 |
2023-08-14 |
mouse |
| b' Taha Kelestemur, Zoltan Nemeth, Pal Pacher, Luca Antonioli, Gy\\xc3\\xb6rgy Hask\\xc3\\xb. A2A Adenosine Receptors Regulate Multiple Organ Failure After Hemorrhagic Shock in Mice. Shock (Augusta, Ga.). 2022-08-26. PMID:36018304.' |
the liver enzymes aspartate transferase (ast) and alanine transaminase (alt) were determined spectrophotometrically from plasma. |
2022-08-26 |
2023-08-14 |
mouse |
| Kate Turner, Corrin Boyd, Gabriele Rossi, Claire R Sharp, Melissa A Claus, Abbie Francis, Lisa Smar. Allergy, inflammation, hepatopathy and coagulation biomarkers in dogs with suspected anaphylaxis due to insect envenomation. Frontiers in veterinary science. vol 9. 2022-08-25. PMID:36003410. |
to compare concentrations of biomarkers of; allergy [mast cell tryptase (mct) and histamine], inflammation [interleukin (il)-6,-10, and-18, cxcl8, ccl2, keratinocyte chemoattractant (kc), c-reactive protein (crp)], endothelial glycocalyx shedding (hyaluronan), coagulation [prothrombin time, activated partial thromboplastin time, fibrinogen concentration, and von willebrand factor antigen, protein c (pc) and antithrombin (at) activity], and hepatopathy [alanine transaminase (alt), aspartate transaminase (ast), alkaline phosphatase (alp), and total bilirubin] between dogs with anaphylaxis after suspected insect exposure, dogs with critical illness, and healthy dogs. |
2022-08-25 |
2023-08-14 |
Not clear |
| Yun-Chih Yeh, Chien-Chou Chen, Shih-Hua Li. Case report: Severe rhabdomyolysis and acute liver injury in a high-altitude mountain climber. Frontiers in medicine. vol 9. 2022-08-25. PMID:36004378. |
the most striking blood laboratory data included creatine kinase (ck) 33,765 iu/l, inappropriately high aspartate aminotransferase (ast) 2,882 iu/l and alanine aminotransferase (alt) 2,259 iu/l (ck/ast ratio 11.7, ck/alt ratio 14.9), creatinine 1.5 mg/dl, serum urea nitrogen (bun) 26 mg/dl, total bilirubin 1.7 mg/dl, ammonia 147 μg/ml, lactate 2.5 mmol/l, and prothrombin time 17.8 s. the meticulous search for the underlying causes of acute liver injury was non-revealing. |
2022-08-25 |
2023-08-14 |
Not clear |
| Qichen Chen, Mingxia Li, Jinghua Chen, Zhen Huang, Xiao Chen, Hong Zhao, Jianqiang Ca. AST·MLR index and operation injury condition are novel prognostic predictor for the prediction of survival in patients with colorectal cancer liver metastases undergoing surgical resection. BMC cancer. vol 22. issue 1. 2022-08-25. PMID:36008803. |
the prognostic values of preoperative aspartate aminotransferase (ast), monocyte-to-lymphocyte ratio (mlr), ast·mlr index (amlri) and operation injury condition in patients with colorectal cancer liver metastases (crlm) remains unclear. |
2022-08-25 |
2023-08-14 |
Not clear |
| Yan Zhao, Yongbo Zhao, Mengyuan Li, Yicheng Zhou, Yijun Zhang, Xin Su, Ziyi Zhang, Liping Ji. Association of COVID-19 vaccination before conception with maternal liver function during early pregnancy: a cohort study of 7745 Chinese pregnant women. Emerging microbes & infections. 2022-08-24. PMID:36000197. |
serum levels of alanine transaminase (alt), aspartate transaminase (ast), total bile acid (tba) and total bilirubin (tbil) in early pregnancy were determined by enzymatic methods. |
2022-08-24 |
2023-08-14 |
Not clear |
| Takumi Yokokawa, Shohei Sasaki, Kohei Sase, Naomi Yoshii, Jun Yasuda, Tatsuya Hayashi, Satoshi Fujit. Association of serum brain-derived neurotrophic factor with hepatic enzymes, AST/ALT ratio, and FIB-4 index in middle-aged and older women. PloS one. vol 17. issue 8. 2022-08-23. PMID:35998179. |
to test this hypothesis, in this cross-sectional study, we investigated whether serum bdnf concentration is associated with liver enzyme activity, aspartate aminotransferase (ast)/ alanine aminotransferase (alt) ratio, and fibrosis-4 (fib-4) index in middle-aged and older women. |
2022-08-23 |
2023-08-14 |
Not clear |
| Cai Zhang, Chenxu Li, Qi Shao, Sudan Meng, Xueying Wang, Tao Kong, Yu L. Antioxidant monoammonium glycyrrhizinate alleviates damage from oxidative stress in perinatal cows. Journal of animal physiology and animal nutrition. 2022-08-22. PMID:35989475. |
the administration of 3 g/day and 6 g/day mag decreased serum aspartate transaminase (ast) at 3 day post-partum. |
2022-08-22 |
2023-08-14 |
cattle |
| Arezoo Mohammadi, Sohrab Kazemi, Inas Molayousefian, Marzieh Pirzadeh, Ali Akbar Moghadamni. Galangin Nanoparticles Protect Acetaminophen-Induced Liver Injury: A Biochemical and Histopathological Approach. Evidence-based complementary and alternative medicine : eCAM. vol 2022. 2022-08-22. PMID:35990838. |
the activity of alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), as well as biochemical factors frap and mda in serum were measured and a histopathological study was performed. |
2022-08-22 |
2023-08-14 |
mouse |
| Huaguo Chen, Chengxiang Zhu, Xin Zho. Effects of Lead and Cadmium Combined Heavy Metals on Liver Function and Lipid Metabolism in Mice. Biological trace element research. 2022-08-22. PMID:35994140. |
pb-cd also caused liver enlargement, significantly increased aspartate aminotransferase (ast) and alanine aminotransferase (alt) enzyme activities, and resulted in pathological changes to the liver. |
2022-08-22 |
2023-08-14 |
mouse |
| Yan Huang, Jialuo Jiang, Wenlin Wang, Jiafu Guo, Nannan Yang, Jian Zhang, Qiuyan Liu, Yan Chen, Tingting Hu, Chaolong Ra. Zanthoxylum armatum DC. extract induces liver injury via autophagy suppression and oxidative damage by activation of mTOR/ULK1 pathway. Toxicon : official journal of the International Society on Toxinology. 2022-08-17. PMID:35977614. |
levels of serum alanine transaminase (alt), aspartate transaminase (ast), and alkaline phosphatase (alp) in the high dose group increased. |
2022-08-17 |
2023-08-14 |
rat |
| Ramazan Denızlı, Bedri Sakcak, Nihat Farisoğulları, Melis Ece Men Peker, Selcan Sınacı, Özgür Kara, Atakan Tanacan, Özlem Moraloğlu Tekın, Dilek Şahı. The İmpact of Elevated Liver Enzymes and İntrahepatic Cholestasis of Pregnancy on the Course of COVID-19 in Pregnant Women. SN comprehensive clinical medicine. vol 4. issue 1. 2022-08-16. PMID:35971435. |
patients with liver enzyme levels higher than twice the upper limit of the reference range for aspartate aminotransferase(ast) and/or alanine aminotransferase (alt) were included. |
2022-08-16 |
2023-08-14 |
Not clear |