| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Israr Ahmad, Smriti Shukla, Ashutosh Kumar, Brajesh Kumar Singh, Vinod Kumar, Amit Kumar Chauhan, Dhirendra Singh, Haushila Prasad Pandey, Chetna Sing. Biochemical and molecular mechanisms of N-acetyl cysteine and silymarin-mediated protection against maneb- and paraquat-induced hepatotoxicity in rats. Chemico-biological interactions. vol 201. issue 1-3. 2013-04-22. PMID:23159886. |
the levels of hepatotoxicity markers - alanine aminotransaminase (alt), aspartate aminotransaminase (ast) and total bilirubin, histological changes, oxidative stress indices, phase i and phase ii xenobiotic metabolizing enzymes - cytochrome p450 (cyp) and glutathione s-transferase (gst) and pro-inflammatory molecules - inducible nitric oxide synthase (inos), tumor necrosis factor-α (tnf-α) and interleukin-1β (il-1β) were measured in animals treated with mb and/or pq in the presence or absence of nac and sil. |
2013-04-22 |
2023-08-12 |
rat |
| Haiqing Yi, Beth L Thurberg, Sarah Curtis, Stephanie Austin, John Fyfe, Dwight D Koeberl, Priya S Kishnani, Baodong Su. Characterization of a canine model of glycogen storage disease type IIIa. Disease models & mechanisms. vol 5. issue 6. 2013-04-19. PMID:22736456. |
monthly blood biochemistry revealed elevated and gradually increasing serum alanine transaminase (alt), aspartate transaminase (ast) and alkaline phosphatase (alp) activities; serum creatine phosphokinase (cpk) activity exceeded normal range after 12 months. |
2013-04-19 |
2023-08-12 |
dog |
| Xiaoyan Wang, Lining Zhang, Zengtao Wei, Xia Zhang, Qi Gao, Yanyan Ma, Xingli Liu, Yang Jiang, Xianglan Liu, Chun Guo, Xiaoyan Wan. The inhibitory action of PDCD4 in lipopolysaccharide/D-galactosamine-induced acute liver injury. Laboratory investigation; a journal of technical methods and pathology. vol 93. issue 3. 2013-04-17. PMID:23295647. |
our results showed that liver-to-body weight ratios, as well as serum aspartate transaminase (ast) and alanine transaminase (alt) levels were significantly increased in pdcd4-deficient mice than wt mice. |
2013-04-17 |
2023-08-12 |
mouse |
| Rabab H Sayed, Hesham A Salem, Bahia M El-Saye. Potential protective effect of taurine against dibromoacetonitrile-induced neurotoxicity in rats. Environmental toxicology and pharmacology. vol 34. issue 3. 2013-04-11. PMID:23021633. |
further, dban produced significant decrease of monoamines, γ-aminobutyric acid (gaba), glutamate contents, acetylcholinestrase (ache) and aspartate aminotransferase (ast) activities, in rat brain. |
2013-04-11 |
2023-08-12 |
human |
| Seon Yeong Lee, Eunju Sung, Yoosoo Chan. Elevated serum gamma-glutamyltransferase is a strong marker of insulin resistance in obese children. International journal of endocrinology. vol 2013. 2013-04-11. PMID:23573088. |
measures acquired included weight, height, percent body fat (bf%), waist circumference, blood pressure, blood glucose and insulin, c-reactive protein, total cholesterol, triglycerides, hdl-cholesterol, ggt, aspartate aminotransferase (ast), and alanine aminotransferase (alt). |
2013-04-11 |
2023-08-12 |
Not clear |
| Hai-Long Zhao, Chang Ho Song, Ok Hee Cha. Negative effects of curcumin on liver injury induced by alcohol. Phytotherapy research : PTR. vol 26. issue 12. 2013-04-09. PMID:22422620. |
ethanol accelerates serum levels of serum aspartate aminotransferase (ast) and alanine aminotransferase (alt), liver injury, production of tumor necrosis factor-alpha (tnf-α), transforming growth factor-beta (tgf-β) and nuclear factor-kappa b (nf-κb) during 5% ethanol-induced liver injury. |
2013-04-09 |
2023-08-12 |
mouse |
| Ken-ichi Komatsu, Hiroko Tanaka, Daisuke Nakagawa, Keiko Kawashim. [Effect of notoginseng extracts and their components on lipopolysaccharide and galactosamine mixture-induced impaired hepatic function in mice]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 132. issue 7. 2013-04-08. PMID:22790029. |
the levels of serum aspartate amino transferase (ast), alanine aminotransferase (alt), tumor necrosis factor (tnf)-α, and interferon (ifn)-γ were measured using commercial assay kits. |
2013-04-08 |
2023-08-12 |
mouse |
| Chen Pan, Li-jun Xu, Rui Zhou, Wen Zhou, Jian-rong Huan. [Multivariate analysis of hepatic encephalopathy occurrence in patients with liver failure]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. vol 20. issue 6. 2013-04-08. PMID:23044200. |
clinical data (sex, age, family history, liver cirrhosis, diabetes, celiac infection, pulmonary infection, liver kidney syndrome, upper gastrointestinal hemorrhage) and laboratory findings (albumin, globulin, total bilirubin, direct bilirubin, alanine aminotransferase, aspartate aminotransferase (ast), gamma-glutamyl transferase, alkaline phosphatase, cholesterol, cholinesterase, k+, na+, creatinine, international normalized ratio (inr), alpha-fetoprotein, hbv dna, white blood cell, hemoglobin, platelet) were collected and used to screen the risk factors for hepatic encephalopathy by univariate and multiple regress analyses. |
2013-04-08 |
2023-08-12 |
Not clear |
| Gajendra Kumar, Amita Srivastava, Surinder Kumar Sharma, Yogendra Kumar Gupt. Safety and efficacy evaluation of Ayurvedic treatment (Arjuna powder and Arogyavardhini Vati) in dyslipidemia patients: A pilot prospective cohort clinical study. Ayu. vol 33. issue 2. 2013-04-08. PMID:23559790. |
safety assessments included hepatic function (aminotransferase (alt), aspartate transaminase (ast), alkaline phosphatase (alp), bilirubin, and β(2) microglobulin), renal function (urea and creatinine and ngal) tests, and urine mercury level. |
2013-04-08 |
2023-08-12 |
Not clear |
| Hınç Yılmaz, Alper Keten, Emre Karacaoğlu, Engin Tutkun, Ramazan Akça. Analysis of the hematological and biochemical parameters related to lead intoxication. Journal of forensic and legal medicine. vol 19. issue 8. 2013-04-05. PMID:23084307. |
no significant difference was found in terms of alanine aminotransferase (alt) and aspartate aminotransferase (ast) values. |
2013-04-05 |
2023-08-12 |
Not clear |
| Jin Pub Son, Mi-Kyung Son, Seoung-Wook Jun, Hyun-Hee Kwak, Soo Hyoung Kang, Jung Seok Kang, Young In Par. Effects of a new sustained-release microsphere formulation of exenatide, DA-3091, on obese and non-alcoholic fatty liver disease mice. Die Pharmazie. vol 68. issue 1. 2013-04-05. PMID:23444782. |
in nafld mice, a significant reduction in serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels, representative markers of hepatic injury, was observed after biweekly subcutaneous administration of 1 mg/kg and 2 mg/kg of da-3091 for 8 weeks. |
2013-04-05 |
2023-08-12 |
mouse |
| Vandana Panda, Hardik Ashar, Sudhamani Srinat. Antioxidant and hepatoprotective effect of Garcinia indica fruit rind in ethanol-induced hepatic damage in rodents. Interdisciplinary toxicology. vol 5. issue 4. 2013-04-05. PMID:23554565. |
levels of marker enzymes (aspartate aminotransferase (ast), alanine aminotransferase (alt) and alkaline phosphatase (alp)), triglyceride (stg), albumin (alb) and total protein (tp) were evaluated in serum. |
2013-04-05 |
2023-08-12 |
rat |
| Hong Zhu, Yang Zhang, Xiaoyu Hu, Cheng Yi, Sen Zhong, Yanyan Wang, Fang Yan. The effects of high-dose qinggan huoxue recipe on acute liver failure induced by d-galactosamine in rats. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-04-05. PMID:23554835. |
after treatment, the blood alanine aminotransferase (alt), aspartate aminotransferase (ast), total bilirubin (tbil), albumin (alb), cholinesterase (che), and prothrombin time (pt) were determined. |
2013-04-05 |
2023-08-12 |
rat |
| Asma Sadaf, Basit Zeshan, Zhuyuan Wang, Ruohu Zhang, Shuhong Xu, Chunlei Wang, Yiping Cu. Toxicity evaluation of hydrophilic CdTe quantum dots and CdTe@SiO2 nanoparticles in mice. Journal of nanoscience and nanotechnology. vol 12. issue 11. 2013-04-04. PMID:23421208. |
the concentration of biochemical markers of hepatic damage, alanine amino transferase (alt) and aspartate aminotransferase (ast) were in the normal range in all the groups. |
2013-04-04 |
2023-08-12 |
mouse |
| Xiaowen Zhou, Yi Ya. Unexpected Nephrotoxicity in Male Ablactated Rats Induced by Cordyceps militaris: The Involvement of Oxidative Changes. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-03-28. PMID:23533520. |
noticeable increments of serum aspartate and alanine aminotransferase (alt and ast) levels were observed for both sexes, suggestive of weak hepatic toxicity. |
2013-03-28 |
2023-08-12 |
rat |
| Ndatsu Yakubu, Ganiyu Oboh, Amuzat Aliyu Olaleka. Antioxidant and Hepatoprotective Properties of Tofu (Curdle Soymilk) against Acetaminophen-Induced Liver Damage in Rats. Biotechnology research international. vol 2013. 2013-03-28. PMID:23533782. |
the analysis of serum alanine aminotransferase (alt), alkaline phosphatase (alp), aspartate aminotransferase (ast), and lactate dehydrogenase (ldh) activities and the concentrations of albumin, total protein, cholesterol, and bilirubin were analyzed. |
2013-03-28 |
2023-08-12 |
rat |
| Jamshid Vafaeimanesh, Mohammad Bagherzadeh, Mahmoud Parha. Adrenal insufficiency as a cause of acute liver failure: a case report. Case reports in endocrinology. vol 2013. 2013-03-28. PMID:23533837. |
her laboratory tests revealed prothrombin time: 21 sec, alanine aminotransferase (alt): 2339 iu/l, aspartate aminotransferase (ast): 2002 iu/l, and alp: 90 iu/l. |
2013-03-28 |
2023-08-12 |
Not clear |
| Chokkalingam Kavitha, Mathan Ramesh, Satyanarayanan Senthil Kumaran, Srinivasan Audhi Lakshm. Toxicity of Moringa oleifera seed extract on some hematological and biochemical profiles in a freshwater fish, Cyprinus carpio. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 64. issue 7-8. 2013-03-26. PMID:21282048. |
biochemical parameters such as plasma protein and glucose levels significantly declined in fish exposed to seed extract while a significant (p<0.05) increase in aspartate aminotransferase (ast), alanine aminotransferase (alt) and alkaline phosphatase (alp) activity was observed. |
2013-03-26 |
2023-08-12 |
Not clear |
| Li-Hua Pan, Jun Lu, Jian-Ping Luo, Xue-Qiang Zha, Jun-Hui Wan. Preventive effect of a galactoglucomannan (GGM) from Dendrobium huoshanense on selenium-induced liver injury and fibrosis in rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 64. issue 7-8. 2013-03-26. PMID:21530204. |
oral administration of ggm effectively attenuated the toxicity of selenite to liver tissue, which was judged both by the decreased activities of serum hepatic enzymes, including alanine aminotransferase (alt), aspartate aminotransferase (ast) and lactate dehydrogenase (ldh), and by liver histopathological examination. |
2013-03-26 |
2023-08-12 |
rat |
| Amar S More, Rashmi R Kumari, Gaurav Gupta, Kandasamy Kathirvel, Milindmitra K Lonare, Rohini S Dhayagude, Dhirendra Kumar, Dinesh Kumar, Anil K Sharma, Surendra K Tanda. Effect of S-methylisothiourea in acetaminophen-induced hepatotoxicity in rat. Naunyn-Schmiedeberg's archives of pharmacology. vol 385. issue 11. 2013-03-26. PMID:22885820. |
at 6 and 24 h, blood was collected to measure alanine transaminase (alt), aspartate transaminase (ast), and nitrate plus nitrite (nox) levels in serum. |
2013-03-26 |
2023-08-12 |
rat |