| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Sánchez-Yagüe, J A Cabezas, M Llanill. Subcellular distribution and characterization of acetylcholinesterase activities from sheep platelets: relationships between temperature-dependence and environment. Blood. vol 76. issue 4. 1990-09-18. PMID:2383654. |
acetylcholinesterase is a key enzyme in cholinergic neurotransmission for hydrolyzing acetylcholine and has been shown to possess arylacylamidase activity in addition to esterase activity. |
1990-09-18 |
2023-08-11 |
Not clear |
| D H Smal. Non-cholinergic actions of acetylcholinesterases: proteases regulating cell growth and development? Trends in biochemical sciences. vol 15. issue 6. 1990-09-10. PMID:2200163. |
the enzyme acetylcholinesterase has a well-established function in limiting the duration of acetylcholine's action at cholinergic synapses. |
1990-09-10 |
2023-08-11 |
Not clear |
| D F Emerich, T J Wals. Cholinergic cell loss and cognitive impairments following intraventricular or intradentate injection of colchicine. Brain research. vol 517. issue 1-2. 1990-09-05. PMID:2375986. |
the decreases in presynaptic cholinergic parameters were paralleled by a reduction in acetylcholinesterase staining in the hippocampus which appeared to recover within 9 weeks. |
1990-09-05 |
2023-08-11 |
rat |
| R J Schotzinger, S C Landi. Acquisition of cholinergic and peptidergic properties by sympathetic innervation of rat sweat glands requires interaction with normal target. Neuron. vol 5. issue 1. 1990-08-22. PMID:2369522. |
the innervation of the transplanted parotid gland did not develop a cholinergic phenotype, as assessed by choline acetyltransferase activity and acetylcholinesterase immunoreactivity, but continued to express intense catecholamine fluorescence. |
1990-08-22 |
2023-08-11 |
rat |
| J C Szerb, A Fin. Is glutamate a co-transmitter in cortical cholinergic terminals? Effects of nucleus basalis lesion and of presynaptic muscarinic agents. Brain research. vol 515. issue 1-2. 1990-08-01. PMID:1972643. |
to obtain additional evidence in support of the co-transmitter role of glutamate in cortical cholinergic terminals proposed by docherty et al., the right nucleus basalis in rats was lesioned with ibotenic acid; resulting changes in cortical acetylcholinesterase (ache) staining, glutamate content, and the release of [3h]acetylcholine ([ 3h]ach) and glutamate from cortical slices from the two sides were compared. |
1990-08-01 |
2023-08-11 |
rat |
| R B Illin. Choline acetyltransferase-like immunoreactivity in the superior colliculus of the cat and its relation to the pattern of acetylcholinesterase staining. The Journal of comparative neurology. vol 296. issue 1. 1990-07-31. PMID:2358529. |
in this part of the brain, the presence of the putative cholinergic terminals could fully account for the distribution of acetylcholinesterase activity. |
1990-07-31 |
2023-08-11 |
cat |
| C Geula, M M Mesula. Cortical cholinergic fibers in aging and Alzheimer's disease: a morphometric study. Neuroscience. vol 33. issue 3. 1990-07-02. PMID:2636703. |
a histochemical method for acetylcholinesterase was used to assess the regional density of acetylcholinesterase-rich (putatively cholinergic) axons in the cerebral cortex. |
1990-07-02 |
2023-08-11 |
human |
| F C Liu, A M Graybiel, S B Dunnett, R W Baughma. Intrastriatal grafts derived from fetal striatal primordia: II. Reconstitution of cholinergic and dopaminergic systems. The Journal of comparative neurology. vol 295. issue 1. 1990-06-27. PMID:1971286. |
for the cholinergic system, a modular organization was found in the striatal grafts with stains for choline acetyltransferase and acetylcholinesterase, respectively the synthetic and degradative enzymes for cholinergic neurons; by autoradiographic [3h]hemicholinium binding, specific for high affinity choline uptake sites associated with cholinergic terminals; and by autoradiographic [3h]pirenzepine binding, selective for m1 receptors. |
1990-06-27 |
2023-08-11 |
rat |
| M C Altavista, P Rossi, A R Bentivoglio, P Crociani, A Albanes. Aging is associated with a diffuse impairment of forebrain cholinergic neurons. Brain research. vol 508. issue 1. 1990-06-20. PMID:2337791. |
butcher's technique for acetylcholinesterase allowed us to identify neurons located in these forebrain nuclei, which stained intensely or moderately for the enzyme and were putatively cholinergic. |
1990-06-20 |
2023-08-11 |
rat |
| E L Sutin, D M Jacobowit. Localization of substance P mRNA in cholinergic cells of the rat laterodorsal tegmental nucleus: in situ hybridization histochemistry and immunocytochemistry. Cellular and molecular neurobiology. vol 10. issue 1. 1990-06-14. PMID:1692261. |
in situ hybridization histochemical techniques in combination with immunocytochemistry and acetylcholinesterase (ache) histochemistry were used to study the colocalization of messenger rna (mrna) encoding the neuropeptide substance p (sp) in cholinergic cells of the laterodorsal tegmental nucleus (ldt) of the rat pontine brain stem. |
1990-06-14 |
2023-08-11 |
rat |
| P Tekulics, Z Rakonczay, P Szerdahelyi, P Kása, K Guly. Effects of ischemia on cholinergic neurotransmission and electrolyte content in newborn pig lumbar spinal cord. Life sciences. vol 46. issue 11. 1990-05-10. PMID:2157120. |
the biochemical changes of the elements of cholinergic neurotransmission (choline acetyltransferase, chat; acetylcholinesterase, ache; butyrylcholinesterase, buche; and muscarinic cholinergic receptors, machr) as well as the electrolyte content were studied in ischemic lumbar spinal cord segments of newborn pigs. |
1990-05-10 |
2023-08-11 |
Not clear |
| K Halasy, J Nemcsók, I Benedeczky, L Tóth, P Sáros. Acetylcholinesterase in the alimentary canal of fish: light and electron microscopic detection, quantitative distribution in different segments of the gut. Acta histochemica. vol 87. issue 2. 1990-04-12. PMID:2516680. |
the morphological findings and the higher acetylcholinesterase activity in the tench foregut and midgut suggest that the enteric striated musculature is endowed with denser cholinergic innervation than the enteric smooth musculature. |
1990-04-12 |
2023-08-11 |
Not clear |
| B H Gähwiler, D A Brown, A Enz, T Knöpfe. Development of the septohippocampal projection in vitro. EXS. vol 57. 1990-03-15. PMID:2533095. |
the presence of cholinergic neurons within the septal slices was demonstrated by histochemical staining techniques for acetylcholinesterase or by golgi-like immunoperoxidase techniques with antibodies raised against the enzyme choline acetyltransferase. |
1990-03-15 |
2023-08-11 |
Not clear |
| B H Gähwiler, D A Brown, A Enz, T Knöpfe. Development of the septohippocampal projection in vitro. EXS. vol 57. 1990-03-15. PMID:2533095. |
application of nerve growth factor (ngf) strongly increased the number of cholinergic fibers which invaded the hippocampal slices and raised the activities of the cholinergic enzymes choline acetyltransferase and acetylcholinesterase, effects which were completely blocked by anti-ngf antibodies. |
1990-03-15 |
2023-08-11 |
Not clear |
| C Grothe, D Otto, M Frotscher, K Unsicke. A role of basic fibroblast growth factor for rat septal neurons. EXS. vol 57. 1990-03-15. PMID:2533096. |
the portions of cholinergic and gabaergic neurons did not change after ngf- and bfgf-treatment (acetylcholinesterase cytochemistry, anti-gaba immunocytochemistry). |
1990-03-15 |
2023-08-11 |
rat |
| A Represa, Y Ben-Ar. Effects of colchicine treatment on the cholinergic septohippocampal system. EXS. vol 57. 1990-03-15. PMID:2533099. |
the destruction of dentate granular cells by colchicine injection promotes a significant increase in the density of acetylcholinesterase staining and cholinergic-muscarinic receptors in the zone denervated by the terminal axons of granular cells, which supports the hypothesis of a proliferation of cholinergic fibers in ca3. |
1990-03-15 |
2023-08-11 |
Not clear |
| G Raivich, G W Kreutzber. Topography of beta NGF receptor-positive and AChE-reactive neurons in the central nervous system. EXS. vol 57. 1990-03-15. PMID:2558908. |
to learn more about the action of beta ngf in the central nervous system we have mapped the distribution of beta ngf receptors and compared it with that of acetylcholinesterase (ache), a sensitive enzyme marker for cholinergic neurons. |
1990-03-15 |
2023-08-11 |
Not clear |
| T N Robinson, R J De Souza, A J Cross, A R Gree. The mechanism of tetrahydroaminoacridine-evoked release of endogenous 5-hydroxytryptamine and dopamine from rat brain tissue prisms. British journal of pharmacology. vol 98. issue 4. 1990-03-14. PMID:2611486. |
1 tetrahydroaminoacridine (tha) is an acetylcholinesterase (ache) inhibitor which may have a greater therapeutic effect in alzheimer-type dementia (atd) than other cholinergic agents. |
1990-03-14 |
2023-08-11 |
rat |
| N J Woolf, L L Butche. Cholinergic systems in the rat brain: IV. Descending projections of the pontomesencephalic tegmentum. Brain research bulletin. vol 23. issue 6. 1990-03-08. PMID:2611694. |
descending projections from cholinergic neurons in the pedunculopontine and laterodorsal tegmental nuclei, collectively referred to as the pontomesencephalotegmental (pmt) cholinergic complex, were studied by use of the fluorescent retrograde tracers fluorogold, true blue, or evans blue in combination with choline acetyltransferase (chat) immunohistochemistry of acetylcholinesterase (ache) pharmacohistochemistry. |
1990-03-08 |
2023-08-11 |
rat |
| A Peñalva, C Muruais, F F Casanueva, C Diegue. Effect of enhancement of endogenous cholinergic tone with pyridostigmine on the dose-response relationships of growth hormone (GH)-releasing hormone-induced GH secretion in normal subjects. The Journal of clinical endocrinology and metabolism. vol 70. issue 2. 1990-03-07. PMID:2105328. |
recently, it has been shown that enhancement of cholinergic tone with the acetylcholinesterase inhibitor pyridostigmine (pd), which presumably acts by inhibiting somatostatin release, stimulates basal gh secretion and gh responses to a maximal dose of ghrh. |
1990-03-07 |
2023-08-11 |
human |