| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Z S L. [Changes in acetylcholine and acetylcholinesterase in blood during pulmonary hypertension]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases. vol 15. issue 2. 1992-11-25. PMID:1394603. |
comparing 30 cases of acute attack period of chronic pulmonary heart disease with 30 cases of normal persons, rbc acetylcholinesterase decreased significantly, indicating that hyperfunction of cholinergic nerve existed in pulmonary hypertension and pulmonary heart disease. |
1992-11-25 |
2023-08-11 |
rat |
| P P De Deyn, R D'Hooge, B Marescau, Y Q Pe. Chemical models of epilepsy with some reference to their applicability in the development of anticonvulsants. Epilepsy research. vol 12. issue 2. 1992-11-23. PMID:1396544. |
the following compounds are reviewed: pentylenetetrazol, bicuculline, penicillin, picrotoxin, beta-carbolines, 3-mercaptopropionic acid, hydrazides, allylglycine; the glycine antagonist strychnine; gamma-hydroxybutyrate; excitatory amino acids (glutamate, aspartate, n-methyl-d-aspartate, quisqualate, kainate, quinolinic acid); monosubstituted guanidino compounds, metals (alumina, cobalt, zinc, iron); neuropeptides (opioid peptides, corticotropin releasing factor, somatostatin, vasopressin); cholinergic agents (acetylcholine, acetylcholinesterase inhibitors, pilocarpine); tetanus toxin; flurothyl; folates; homocysteine and colchicine. |
1992-11-23 |
2023-08-11 |
Not clear |
| J Sirviö, P J Riekkine. Brain and cerebrospinal fluid cholinesterases in Alzheimer's disease, Parkinson's disease and aging. A critical review of clinical and experimental studies. Journal of neural transmission. Parkinson's disease and dementia section. vol 4. 1992-11-17. PMID:1388703. |
acetylcholinesterase (ache), an enzyme responsible for the break-down of acetylcholine, is found both in cholinergic and non-cholinergic neurons in the central nervous system. |
1992-11-17 |
2023-08-11 |
Not clear |
| M M Mesulam, D Mash, L Hersh, M Bothwell, C Geul. Cholinergic innervation of the human striatum, globus pallidus, subthalamic nucleus, substantia nigra, and red nucleus. The Journal of comparative neurology. vol 323. issue 2. 1992-11-03. PMID:1401259. |
the anatomical organization of cholinergic markers such as acetylcholinesterase, choline acetyltransferase, and nerve growth factor receptors was investigated in the basal ganglia of the human brain. |
1992-11-03 |
2023-08-11 |
human |
| B Günther, P Clausin. Cholinergic and adrenergic drugs affect delayed type hypersensitivity in C57BL/6 mice. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie. vol 192. issue 2. 1992-10-20. PMID:1529165. |
the cholinergic agonist nicotine and the acetylcholinesterase inhibitor physostigmine decreased dth, whereas the alpha-adrenergic agonist clonidine stimulated dth. |
1992-10-20 |
2023-08-11 |
mouse |
| G J Sengstock, K B Johnson, P T Jantzen, E M Meyer, A J Dunn, G W Arendas. Nucleus basalis lesions in neonate rats induce a selective cortical cholinergic hypofunction and cognitive deficits during adulthood. Experimental brain research. vol 90. issue 1. 1992-10-15. PMID:1521605. |
histological analysis of the subcortex from lesioned animals during adulthood revealed: (1) a substantial reduction in acetylcholinesterase-positive cells (presumably cholinergic) within the nucleus basalis, (2) decreased acetylcholinesterase staining in neocortex and (3) a gliosis essentially restricted to the globus pallidus. |
1992-10-15 |
2023-08-11 |
rat |
| E E Tyrala, S V Mathews, G S Ra. Effect of intrauterine exposure to cocaine on acetylcholinesterase in primary cultures of fetal mouse brain cells. Neurotoxicology and teratology. vol 14. issue 4. 1992-10-15. PMID:1522827. |
utilizing ache as a biochemical marker, these studies have shown that in utero exposure to cocaine has an adverse effect on the normal developmental pattern of the production of acetylcholinesterase in cholinergic neurons in the fetal mouse brain. |
1992-10-15 |
2023-08-11 |
mouse |
| M M Mesulam, C Geul. Overlap between acetylcholinesterase-rich and choline acetyltransferase-positive (cholinergic) axons in human cerebral cortex. Brain research. vol 577. issue 1. 1992-10-09. PMID:1521137. |
these observations show that there is probably a complete correspondence between choline acetyltransferase-positive and acetylcholinesterase-rich axons and that the acetylcholinesterase reaction can be used as a specific marker for cortical cholinergic axons in the adult human brain. |
1992-10-09 |
2023-08-11 |
human |
| G L Forloni, N Angeretti, M Rizzi, A Vezzan. Chronic infusion of quinolinic acid in rat striatum: effects on discrete neuronal populations. Journal of the neurological sciences. vol 108. issue 2. 1992-10-08. PMID:1387677. |
the distribution of somatostatin (som)-positive neurons labelled by immunocytochemistry or by nadph-diaphorase histochemistry and of cholinergic cells stained by acetylcholinesterase was quantified in the peripheral portion of the lesioned area. |
1992-10-08 |
2023-08-11 |
rat |
| L E Trudeau, P Fossier, G Baux, L Tau. Xanthine derivatives IBMX and S-9977-2 potentiate transmission at an Aplysia central cholinergic synapse. Brain research. vol 586. issue 1. 1992-09-29. PMID:1380883. |
the finding that responses to the hydrolysis-resistant cholinergic analogue carbachol were unaffected by the two xanthines suggested that the observed effects were at least partly caused by an inhibition of acetylcholinesterase (ache) activity. |
1992-09-29 |
2023-08-11 |
aplysia |
| Y He, Z Yao, Y Gu, G Kuang, Y Che. Nerve growth factor promotes collateral sprouting of cholinergic fibers in the septohippocampal cholinergic system of aged rats with fimbria transection. Brain research. vol 586. issue 1. 1992-09-29. PMID:1511349. |
controls received intraventricular injections of cytochrome c. a quantitative analysis of acetylcholinesterase (ache)-positive fibers was used to evaluate whether the ngf treatment can stimulate regeneration and reinnervation of the cholinergic axons in the septohippocampal system of aged rats with fimbria transection. |
1992-09-29 |
2023-08-11 |
rat |
| J Quillfeldt, B Bolioli, C Dalmaz, S Rascovsky, C H Huang, M Dias, M B Ferreira, F Schneider, I Izquierdo, J H Medin. Biochemical and behavioral effects of intraseptal microinjection of fasciculin, an irreversible acetylcholinesterase inhibitor. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 24. issue 5. 1992-09-22. PMID:1823265. |
we examined the effect, in rats, of an intraseptal microinjection of fasciculin (fas), an irreversible peptide acetylcholinesterase (ache) inhibitor, on a) ache activity measured in septum and hippocampus, b) 3h-quinuclidinyl benzylate (3h-qnb) and 3h-oxotremorine (3h-oxo) binding to hippocampal cholinergic muscarinic receptors, c) 3h-flunitrazepam (3h-fnz) binding to hippocampal benzodiazepine receptors as a control for qnb and oxo binding, d) acquisition and retention in three different behavioral paradigms, i.e., water-finding (in which there is concomitant habituation to the apparatus), step-down inhibitory avoidance, and shuttle avoidance. |
1992-09-22 |
2023-08-11 |
rat |
| R Silveira, J Stjernschant. Vascular effects of acetylcholinesterase inhibitors in the rabbit eye: a study with fasciculin and physostigmine. Journal of ocular pharmacology. vol 8. issue 2. 1992-09-21. PMID:1506754. |
the reduction in blood flow of the anterior uvea after intracameral injection of acetylcholinesterase inhibitors is consistent with a cholinergic vasoconstriction previously described in the eye during electrical stimulation of the oculomotor nerve. |
1992-09-21 |
2023-08-11 |
rabbit |
| M Konagaya, Y Konagaya, M Iid. [CSF acetylcholinesterase activity in central neurological diseases involving cholinergic systems]. Rinsho shinkeigaku = Clinical neurology. vol 32. issue 3. 1992-08-19. PMID:1628449. |
[csf acetylcholinesterase activity in central neurological diseases involving cholinergic systems]. |
1992-08-19 |
2023-08-11 |
Not clear |
| J Kiss, A J Pate. Development of the cholinergic fibres innervating the cerebral cortex of the rat. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 10. issue 2. 1992-08-18. PMID:1632275. |
the ontogeny of innervation of the cholinergic fibres from the basal forebrain into the cingulate, frontal, parietal and piriform cortices of the rat has been examined using a modified histochemical method of acetylcholinesterase (ache). |
1992-08-18 |
2023-08-11 |
rat |
| R M Ridley, S Gribble, B Clark, H F Baker, A Fin. Restoration of learning ability in fornix-transected monkeys after fetal basal forebrain but not fetal hippocampal tissue transplantation. Neuroscience. vol 48. issue 4. 1992-08-14. PMID:1630624. |
staining was largely restored to normal in the host hippocampus and dentate gyrus in monkeys with cholinergic transplants, whereas acetylcholinesterase staining was abnormal in those with non-cholinergic grafts. |
1992-08-14 |
2023-08-11 |
monkey |
| E K Perry, M Johnson, J M Kerwin, M A Piggott, J A Court, P J Shaw, P G Ince, A Brown, R H Perr. Convergent cholinergic activities in aging and Alzheimer's disease. Neurobiology of aging. vol 13. issue 3. 1992-08-12. PMID:1625768. |
a similar trend was apparent with respect to acetylcholinesterase (ache) histochemical activity associated with fibers and terminals (predominantly cholinergic and concentrated in ca3 and 4 of the hippocampus) but not with reactive perikarya (considered to be noncholinergic) present in both hippocampus and cortex. |
1992-08-12 |
2023-08-11 |
human |
| R P Gaykema, C Nyakas, E Horvath, L B Hersh, C Majtenyi, P G Luite. Cholinergic fiber aberrations in nucleus basalis lesioned rat and Alzheimer's disease. Neurobiology of aging. vol 13. issue 3. 1992-08-12. PMID:1625774. |
innervation density and morphological aberrations of cholinergic fibers were studied with choline acetyltransferase (chat) immunocytochemistry and acetylcholinesterase (ache) histochemistry in 30-35 month-old aged rats and rats with long-term bilateral lesions of the magnocellular basal nucleus (mbn). |
1992-08-12 |
2023-08-11 |
human |
| H Soreq, Y Lapidot-Lifson, H Zaku. A role for cholinesterases in tumorigenesis? Cancer cells (Cold Spring Harbor, N.Y. : 1989). vol 3. issue 12. 1992-08-06. PMID:1820094. |
hydrolysis of the neurotransmitter acetylcholine by acetylcholinesterase (ache) and butyrylcholinesterase (bche) is the rate-limiting step in the termination of cholinergic signaling at neuromuscular junctions. |
1992-08-06 |
2023-08-11 |
human |
| I Alvaro, E Arill. Somatostatin receptor elevation in rat striatum after diisopropylfluorophosphate administration. Brain research bulletin. vol 28. issue 4. 1992-08-05. PMID:1352176. |
the acute and chronic administration of diisopropylfluorophosphate (dfp), an inhibitor of acetylcholinesterase or of atropine, a blocker of muscarinic cholinergic receptors, did not affect somatostatin-like immunoreactivity (sli) content in the striatum of rats. |
1992-08-05 |
2023-08-11 |
rat |