| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W Yao, D A Godfre. Choline acetyltransferase in cochlear root neurons. Hearing research. vol 69. issue 1-2. 1993-12-17. PMID:8226351. |
some of our preparations showed immunoreactivity of somata of cochlear root neurons with both polyclonal and monoclonal antibodies against choline acetyltransferase (chat) which, despite their very weak histochemical reaction for acetylcholinesterase (ache), suggested that cochlear root neurons might be cholinergic. |
1993-12-17 |
2023-08-12 |
rat |
| D L Bellinger, D Lorton, R W Hamill, S Y Felten, D L Felte. Acetylcholinesterase staining and choline acetyltransferase activity in the young adult rat spleen: lack of evidence for cholinergic innervation. Brain, behavior, and immunity. vol 7. issue 3. 1993-12-10. PMID:8219410. |
acetylcholinesterase staining and choline acetyltransferase activity in the young adult rat spleen: lack of evidence for cholinergic innervation. |
1993-12-10 |
2023-08-12 |
rat |
| F Amenta, F Franch, A Ricci, J A Veg. Cholinergic neurotransmission in the hippocampus of aged rats: influence of L-alpha-glycerylphosphorylcholine treatment. Annals of the New York Academy of Sciences. vol 695. 1993-12-10. PMID:8239302. |
the influence of aging and of l-alpha-glycerylphosphorylcholine (gfc) treatment on the acetylcholine synthesizing and degradating enzymes choline acetyltransferase (chat) and acetylcholinesterase (ache) and on cholinergic muscarinic m-1 and m-2 receptors were assessed in the hippocampus using immunocytochemical, histochemical and radioligand binding techniques, respectively. |
1993-12-10 |
2023-08-12 |
rat |
| T C Marr. Organophosphate poisoning. Pharmacology & therapeutics. vol 58. issue 1. 1993-11-12. PMID:8415873. |
the cholinergic syndrome is caused by acetylcholinesterase inhibition, and diagnosis is based on the clinical signs and symptoms as well as the measurement of inhibition of erythrocyte acetylcholinesterase and/or plasma cholinesterase activity. |
1993-11-12 |
2023-08-12 |
Not clear |
| J H McLean, M T Shipley, D I Bernstein, D Corbet. Selective lesions of neural pathways following viral inoculation of the olfactory bulb. Experimental neurology. vol 122. issue 2. 1993-10-26. PMID:8104818. |
no changes in acetylcholinesterase staining in these cortical regions were observed, indicating that cholinergic axons were not significantly changed. |
1993-10-26 |
2023-08-12 |
rat |
| S James, P J Richardso. The subcellular distribution of [3H]-CGS 21680 binding sites in the rat striatum: copurification with cholinergic nerve terminals. Neurochemistry international. vol 23. issue 2. 1993-10-08. PMID:8369737. |
after subcellular fractionation, the distribution of [3h]-cgs 21680 binding was similar to that of the cholinergic nerve terminal marker acetylcholinesterase rather than the more general membrane marker 5'-nucleotidase, with 42% of binding associated with the synaptosomal sub-fraction and 19% with a light membrane fraction. |
1993-10-08 |
2023-08-12 |
rat |
| F Dajas, R Silveira, G Costa, M E Castello, D Jerusalinsky, J Medina, D Levesque, S Greenfiel. Differential cholinergic and non-cholinergic actions of acetylcholinesterase in the substantia nigra revealed by fasciculin-induced inhibition. Brain research. vol 616. issue 1-2. 1993-09-30. PMID:7689409. |
differential cholinergic and non-cholinergic actions of acetylcholinesterase in the substantia nigra revealed by fasciculin-induced inhibition. |
1993-09-30 |
2023-08-12 |
rat |
| E K Perry, J A Court, M Johnson, C J Smith, V James, A V Cheng, J M Kerwin, C M Morris, M A Piggott, J A Edwardso. Autoradiographic comparison of cholinergic and other transmitter receptors in the normal human hippocampus. Hippocampus. vol 3. issue 3. 1993-09-22. PMID:8394772. |
the regional distribution of cholinergic innervation to the normal adult human hippocampus and adjacent cortex, marked by acetylcholinesterase (ache) fiber and terminal reactivity, is notable for its concentration in ca2/3 of ammon's horn and the dentate fascia. |
1993-09-22 |
2023-08-12 |
human |
| P Kugler, A Schleicher, K Zilles, E Horvát. Acetylcholinesterase activity and post-lesional plasticity in the hippocampus of young and aged rats. Neuroscience. vol 55. issue 1. 1993-09-15. PMID:8350995. |
as acetylcholinesterase is considered to be a good cholinergic indicator in the hippocampus, the results suggest a homotypic collateral sprouting from spared cholinergic afferents following ibotenate lesion of the medial septum-diagonal band complex in young and aged rats. |
1993-09-15 |
2023-08-12 |
human |
| C T McDonald, E R McGuinness, J M Allma. Laminar organization of acetylcholinesterase and cytochrome oxidase in the lateral geniculate nucleus of prosimians. Neuroscience. vol 54. issue 4. 1993-09-02. PMID:8393538. |
layer vi of primary visual cortex, which is known to be a source of acetylcholinesterase in the parvocellular layers, does not contain cholinergic cells, nor does the pretectal nucleus, which projects mainly to the parvocellular layers. |
1993-09-02 |
2023-08-12 |
monkey |
| C T McDonald, E R McGuinness, J M Allma. Laminar organization of acetylcholinesterase and cytochrome oxidase in the lateral geniculate nucleus of prosimians. Neuroscience. vol 54. issue 4. 1993-09-02. PMID:8393538. |
the relation of this increased acetylcholinesterase activity to cholinergic function remains unclear. |
1993-09-02 |
2023-08-12 |
monkey |
| O Stewar. Signals that induce sprouting in the central nervous system: sprouting is delayed in a strain of mouse exhibiting delayed axonal degeneration. Experimental neurology. vol 118. issue 3. 1993-08-06. PMID:1284863. |
cholinergic sprouting was then evaluated using a histochemical technique for acetylcholinesterase (ache) in mutant mice and normal controls. |
1993-08-06 |
2023-08-11 |
mouse |
| Z Rakonczay, P Hammond, S Brimijoi. Lesion of central cholinergic systems by systemically administered acetylcholinesterase antibodies in newborn rats. Neuroscience. vol 54. issue 1. 1993-07-20. PMID:8515843. |
lesion of central cholinergic systems by systemically administered acetylcholinesterase antibodies in newborn rats. |
1993-07-20 |
2023-08-12 |
rat |
| Z Rakonczay, P Hammond, S Brimijoi. Lesion of central cholinergic systems by systemically administered acetylcholinesterase antibodies in newborn rats. Neuroscience. vol 54. issue 1. 1993-07-20. PMID:8515843. |
overall, it appeared that acetylcholinesterase antibodies induced widespread but reversible damage of cholinergic fibers and terminals, while sparing cholinergic cell bodies and many other neural systems. |
1993-07-20 |
2023-08-12 |
rat |
| R J Richardson, T B Moore, U S Kayyali, J H Fowke, J C Randal. Inhibition of hen brain acetylcholinesterase and neurotoxic esterase by chlorpyrifos in vivo and kinetics of inhibition by chlorpyrifos oxon in vitro: application to assessment of neuropathic risk. Fundamental and applied toxicology : official journal of the Society of Toxicology. vol 20. issue 3. 1993-07-08. PMID:7684990. |
previous work has shown that the ability of op insecticides to cause acute cholinergic toxicity versus opidn can be predicted from their relative tendency to inhibit the intended target, acetylcholinesterase (ache), versus the putative neuropathic target, nte, in brain tissue. |
1993-07-08 |
2023-08-12 |
human |
| b' A Bilkei-Gorz\\xc3\\xb. Neurotoxic effect of enteral aluminium. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 31. issue 5. 1993-07-07. PMID:8505021.' |
acetylcholinesterase activity increased and choline-acetyltransferase activity decreased, resulting in a diminished cholinergic activity, which is a characteristic of alzheimer's disease. |
1993-07-07 |
2023-08-12 |
rat |
| L J Fuortes, A D Ayebo, B C Kros. Cholinesterase-inhibiting insecticide toxicity. American family physician. vol 47. issue 7. 1993-06-29. PMID:8503347. |
the inhibition of acetylcholinesterase causes accumulation of acetylcholine at nerve endings, resulting in a cholinergic or hypersecretory syndrome. |
1993-06-29 |
2023-08-12 |
Not clear |
| M Pákáski, P Kás. Glial cells in coculture can increase the acetylcholinesterase activity in human brain endothelial cells. Neurochemistry international. vol 21. issue 1. 1993-06-24. PMID:1303138. |
the elements of the cholinergic system (acetylcholinesterase and choline acetyltransferase) and butyrylcholinesterase were studied in human cortical capillary samples, brain-derived endothelial cell cultures and glial cell cultures. |
1993-06-24 |
2023-08-11 |
human |
| T Arendt, M K Brückner, M Lange, V Big. Changes in acetylcholinesterase and butyrylcholinesterase in Alzheimer's disease resemble embryonic development--a study of molecular forms. Neurochemistry international. vol 21. issue 3. 1993-06-24. PMID:1303164. |
the pattern of molecular forms of acetylcholinesterase (ache, ec 3.1.1.7) and butyrylcholinesterase (bche, ec 3.1.1.8) separated by density gradient centrifugation was investigated in the brain and cerebrospinal fluid in alzheimer's disease (ad), in human embryonic brain and in rat brain after experimental cholinergic deafferentation of the cerebral cortex. |
1993-06-24 |
2023-08-11 |
human |
| L L Butcher, J D Oh, N J Woolf, R H Edwards, A Roghan. Organization of central cholinergic neurons revealed by combined in situ hybridization histochemistry and choline-O-acetyltransferase immunocytochemistry. Neurochemistry international. vol 21. issue 3. 1993-06-24. PMID:1303168. |
it is concluded that hybridocytochemistry with digoxigenin-labeled riboprobes confirms the existence of cholinergic neurons in most of the neural regions believed to contain them on the basis of acetylcholinesterase pharmacohistochemistry and choline-o-acetyltransferase immunocytochemistry, with the prominent exceptions of the cerebral cortex, hippocampus, olfactory bulb, anterior olfactory nucleus, and caudal raphe nuclei, which apparently do not possess neurons expressing detectable levels of the mrna for the synthetic enzyme of acetylcholine. |
1993-06-24 |
2023-08-11 |
rat |