| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R J Richardso. Assessment of the neurotoxic potential of chlorpyrifos relative to other organophosphorus compounds: a critical review of the literature. Journal of toxicology and environmental health. vol 44. issue 2. 1995-03-16. PMID:7531775. |
because chlorpyrifos and other op insecticides are designed to produce acute cholinergic effects through inhibition of acetylcholinesterase (ache) and some op compounds can cause op compound-induced delayed neurotoxicity (opidn) via chemical modification of neurotoxic esterase (neuropathy target esterase, nte), this review focuses on the capacity of chlorpyrifos to precipitate these and other adverse neurological consequences. |
1995-03-16 |
2023-08-12 |
rat |
| P Tandon, S Barone, W R Mundy, H A Tilso. Compensatory changes in the hippocampus following intradentate infusion of colchicine. Neurotoxicology. vol 15. issue 3. 1995-03-16. PMID:7854585. |
intradentate colchicine produces a significant increase in choline- acetyltransferase activity and staining for acetylcholinesterase activity in the hippocampus, suggesting reactive synaptogenesis of cholinergic fibers. |
1995-03-16 |
2023-08-12 |
rat |
| P Taylor, Z Radić, H J Kreienkamp, R Maeda, Z Luo, M E Fuentes, D Vellom, N Pickerin. Expression and ligand specificity of acetylcholinesterase and the nicotinic receptor: a tale of two cholinergic sites. Biochemical Society transactions. vol 22. issue 3. 1995-02-16. PMID:7821676. |
expression and ligand specificity of acetylcholinesterase and the nicotinic receptor: a tale of two cholinergic sites. |
1995-02-16 |
2023-08-12 |
Not clear |
| D Rodríguez-Ithurralde, O Vincen. Excitotoxicity and cholinergic chemical markers during programmed motor neurone death. Journal of the neurological sciences. vol 124 Suppl. 1995-02-02. PMID:7807141. |
we measured cholinergic markers and acetylcholinesterase (ache) molecular forms after glutamate receptor stimulation of superfused slices of mouse spinal cord at different developmental ages. |
1995-02-02 |
2023-08-12 |
mouse |
| P Costa, D J Traver, C B Auger, L G Cost. Expression of cholinergic muscarinic receptor subtypes mRNA in rat blood mononuclear cells. Immunopharmacology. vol 28. issue 2. 1995-01-26. PMID:8002286. |
white blood cells have been found to express muscarinic and nicotinic cholinergic receptors as well as acetylcholinesterase on their surface, and cholinergic agents have been shown to modulate immune functions. |
1995-01-26 |
2023-08-12 |
rat |
| E A Van der Zee, P G Luite. Cholinergic and GABAergic neurons in the rat medial septum express muscarinic acetylcholine receptors. Brain research. vol 652. issue 2. 1994-12-29. PMID:7953739. |
the cholinergic transmitter nature of the machr-positive cells was studied using adjacent 8 microns thick serial sections stained immunocytochemically for choline acetyltransferase (chat), or histochemically for acetylcholinesterase (ache). |
1994-12-29 |
2023-08-12 |
rat |
| H T Mount, C F Dreyfus, I B Blac. Muscarinic stimulation promotes cultured Purkinje cell survival: a role for acetylcholine in cerebellar development? Journal of neurochemistry. vol 63. issue 6. 1994-12-23. PMID:7964724. |
the cerebellar cultures exhibited cholinergic neuronal traits: high-affinity choline uptake, and choline acetyltransferase and acetylcholinesterase activities. |
1994-12-23 |
2023-08-12 |
rat |
| T Egashir. [Experimental techniques for developing new drugs acting on dementia (4)--Aged rats]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 14. issue 4. 1994-12-16. PMID:7975929. |
the changes in choline acetyltransferase (chat), acetylcholinesterase (ache), muscarinic receptor binding (machr) and na(+)-dependent high affinity choline uptake (hacu) are generally consistent with age-dependent declines in cholinergic neurotransmission, although these decreases may include differences in strain/species, sex, tissue sampling and assay procedures. |
1994-12-16 |
2023-08-12 |
rat |
| P E Lloyd, P J Churc. Cholinergic neuromuscular synapses in Aplysia have low endogenous acetylcholinesterase activity and a high-affinity uptake system for acetylcholine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 11 Pt 1. 1994-12-06. PMID:7965073. |
cholinergic neuromuscular synapses in aplysia have low endogenous acetylcholinesterase activity and a high-affinity uptake system for acetylcholine. |
1994-12-06 |
2023-08-12 |
aplysia |
| G J Lees, W Leon. Brain lesions induced by specific and non-specific inhibitors of sodium-potassium ATPase. Brain research. vol 649. issue 1-2. 1994-11-30. PMID:7953637. |
the toxicity of a low dose of ouabain appeared to be selective for neuronal perikarya as staining for acetylcholinesterase (present on the nerve terminals of the afferent cholinergic innervation) was unaffected. |
1994-11-30 |
2023-08-12 |
rat |
| A Klegeris, T C Budd, S A Greenfiel. Acetylcholinesterase activation of peritoneal macrophages is independent of catalytic activity. Cellular and molecular neurobiology. vol 14. issue 1. 1994-11-25. PMID:7954662. |
in diverse tissues, acetylcholinesterase appears to play a critical role in the functional state of cells completely dependent of cholinergic transmission. |
1994-11-25 |
2023-08-12 |
rat |
| J H Weiss, H Z Yin, D W Cho. Basal forebrain cholinergic neurons are selectively vulnerable to AMPA/kainate receptor-mediated neurotoxicity. Neuroscience. vol 60. issue 3. 1994-11-17. PMID:7523984. |
we exposed murine basal forebrain neuronal cultures for 24 h to defined concentrations of n-methyl-d-aspartate, kainate or alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate, and assessed the resultant degeneration of the cholinergic neuronal subpopulation, as identified by choline acetyltransferase immunocytochemistry and acetylcholinesterase histochemistry. |
1994-11-17 |
2023-08-12 |
Not clear |
| C S Venugopalan, E P Holmes, H H Jarboe, K M Kleino. Non-adrenergic non-cholinergic (NANC) excitatory response of the channel catfish intestine. Journal of autonomic pharmacology. vol 14. issue 3. 1994-11-02. PMID:7929475. |
the contractile cholinergic responses of the tissues to carbachol and acetylcholine (ach) were blocked by atropine on an equimolar concentration, whereas, these responses were enhanced in the presence of neostigmine, and acetylcholinesterase inhibitor. |
1994-11-02 |
2023-08-12 |
Not clear |
| S De Lacalle, C Lim, T Sobreviela, E J Mufson, L B Hersh, C B Sape. Cholinergic innervation in the human hippocampal formation including the entorhinal cortex. The Journal of comparative neurology. vol 345. issue 3. 1994-10-27. PMID:7929905. |
we studied the cholinergic innervation of the human hippocampal formation by means of immunohistochemistry with polyclonal antisera directed against acetylcholinesterase (ache), choline acetyltransferase (chat), and the low-affinity (p75) nerve growth factor receptor (ngfr). |
1994-10-27 |
2023-08-12 |
human |
| J M Conner, B Fass-Holmes, S Varo. Changes in nerve growth factor immunoreactivity following entorhinal cortex lesions: possible molecular mechanism regulating cholinergic sprouting. The Journal of comparative neurology. vol 345. issue 3. 1994-10-27. PMID:7929909. |
the distribution of the ngf-immunoreactive band exactly coincides with the distribution of sprouting cholinergic terminals revealed by acetylcholinesterase histochemistry or ngf-receptor immunostaining. |
1994-10-27 |
2023-08-12 |
Not clear |
| M Shapira, S Seidman, M Sternfeld, R Timberg, D Kaufer, J Patrick, H Sore. Transgenic engineering of neuromuscular junctions in Xenopus laevis embryos transiently overexpressing key cholinergic proteins. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 19. 1994-10-14. PMID:8090771. |
to examine the role of key cholinergic proteins in the formation of neuromuscular junctions (nmjs), we expressed dnas encoding the mouse muscle nicotinic acetylcholine receptor (nachr) or human brain and muscle acetylcholinesterase (hache) in developing xenopus laevis embryos. |
1994-10-14 |
2023-08-12 |
mouse |
| S Bekpinar, P Oner, F G Eryüre. Comparative effects of chronic administration of some psychotropic drugs on rat brain cortex acetylcholinesterase activity. Progress in neuro-psychopharmacology & biological psychiatry. vol 18. issue 3. 1994-10-06. PMID:8078989. |
the response of central cholinergic neurotransmission to the chronic administration of some psychotropic drugs to rats was investigated using brain acetylcholinesterase activity as a neurochemical marker for cholinergic neurons. |
1994-10-06 |
2023-08-12 |
rat |
| P A Lapchak, D M Araujo, F Heft. Effects of chronic nerve growth factor treatment on hippocampal [3H]cytisine/nicotinic binding sites and presynaptic nicotinic receptor function following fimbrial transections. Neuroscience. vol 60. issue 2. 1994-09-23. PMID:8072684. |
thus, in studies that used partial fimbriectomies to parallel the cholinergic neurodegeneration that occurs in ad, intraventricularly administered nerve growth factor prevented the loss of choline acetyltransferase (chat) and acetylcholinesterase immunoreactivity in the septum and increased a variety of presynaptic cholinergic markers involved in the synthesis, storage and release of the neurotransmitter acetylcholine (for reviews see refs 7, 17, 19). |
1994-09-23 |
2023-08-12 |
Not clear |
| M B Jensen, B González, B Castellano, J Zimme. Microglial and astroglial reactions to anterograde axonal degeneration: a histochemical and immunocytochemical study of the adult rat fascia dentata after entorhinal perforant path lesions. Experimental brain research. vol 98. issue 2. 1994-09-08. PMID:8050511. |
the postlesional connective reorganization of the cholinergic septohippocampal projection was monitored by histochemical staining for acetylcholinesterase. |
1994-09-08 |
2023-08-12 |
rat |
| V Haroutunian, M Davidson, P D Kanof, D P Perl, P Powchik, M Losonczy, J McCrystal, D P Purohit, L M Bierer, K L Davi. Cortical cholinergic markers in schizophrenia. Schizophrenia research. vol 12. issue 2. 1994-08-31. PMID:8043524. |
cholinergic marker activity (choline acetyltransferase and acetylcholinesterase) was significantly diminished in the ad cohort but not in the schizophrenic cohort. |
1994-08-31 |
2023-08-12 |
Not clear |