| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P S Kaeser, T C Südho. RIM function in short- and long-term synaptic plasticity. Biochemical Society transactions. vol 33. issue Pt 6. 2006-02-23. PMID:16246115. |
in ca1-region schaffer-collateral excitatory synapses and in gabaergic synapses (where gaba is gamma-aminobutyric acid), rim1alpha is required for maintaining normal neurotransmitter release and short-term synaptic plasticity. |
2006-02-23 |
2023-08-12 |
mouse |
| Alexandra P Few, Nathan J Lautermilch, Ruth E Westenbroek, Todd Scheuer, William A Catteral. Differential regulation of CaV2.1 channels by calcium-binding protein 1 and visinin-like protein-2 requires N-terminal myristoylation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 30. 2006-02-15. PMID:16049184. |
p/q-type ca2+ currents through presynaptic cav2.1 channels initiate neurotransmitter release, and differential modulation of these channels by neuronal calcium-binding proteins (ncabps) may contribute to synaptic plasticity. |
2006-02-15 |
2023-08-12 |
Not clear |
| T Harkany, M B Dobszay, F Cayetanot, W Härtig, T Siegemund, F Aujard, K Macki. Redistribution of CB1 cannabinoid receptors during evolution of cholinergic basal forebrain territories and their cortical projection areas: a comparison between the gray mouse lemur (Microcebus murinus, primates) and rat. Neuroscience. vol 135. issue 2. 2006-01-25. PMID:16129564. |
endocannabinoid signaling, mediated by presynaptic cb1 cannabinoid receptors on neurons, is fundamental for the maintenance of synaptic plasticity by modulating neurotransmitter release from axon terminals. |
2006-01-25 |
2023-08-12 |
mouse |
| Ana-Maria Florea, Frank Splettstoesser, Elke Dopp, Albert W Rettenmeier, Dietrich Büsselber. Modulation of intracellular calcium homeostasis by trimethyltin chloride in human tumour cells: neuroblastoma SY5Y and cervix adenocarcinoma HeLa S3. Toxicology. vol 216. issue 1. 2005-12-20. PMID:16125831. |
neurotransmitter release, synaptic plasticity, muscular contraction, cell proliferation), while calcium overloads could result in cytotoxicity. |
2005-12-20 |
2023-08-12 |
human |
| Scott A Burchet. Psychostimulants, madness, memory... and RGS proteins? Neuromolecular medicine. vol 7. issue 1-2. 2005-12-08. PMID:16052041. |
by regulating corticostriatal synaptic plasticity, rgs proteins can influence presynaptic activity, neurotransmitter release, and postsynaptic depolarization and thereby play a key role in the development of this plasticity. |
2005-12-08 |
2023-08-12 |
Not clear |
| Sarah Tosato, Paola Dazzan, David Collie. Association between the neuregulin 1 gene and schizophrenia: a systematic review. Schizophrenia bulletin. vol 31. issue 3. 2005-12-07. PMID:16081509. |
neuregulin 1 (nrg1) is a plausible susceptibility gene because of its involvement in neurodevelopment, regulation of glutamate and other neurotransmitter receptor expression, and synaptic plasticity. |
2005-12-07 |
2023-08-12 |
human |
| Takashi Yamauch. Neuronal Ca2+/calmodulin-dependent protein kinase II--discovery, progress in a quarter of a century, and perspective: implication for learning and memory. Biological & pharmaceutical bulletin. vol 28. issue 8. 2005-11-30. PMID:16079472. |
neuronal cam kinase ii regulates important neuronal functions, including neurotransmitter synthesis, neurotransmitter release, modulation of ion channel activity, cellular transport, cell morphology and neurite extension, synaptic plasticity, learning and memory, and gene expression. |
2005-11-30 |
2023-08-12 |
Not clear |
| Yoshitake Yamauchi, Li-Hong Qin, Makoto Nishihara, Ken Sawada, Kunio Kato, Shimpei Inou. Vulnerability of synaptic plasticity in the complexin II knockout mouse to maternal deprivation stress. Brain research. vol 1056. issue 1. 2005-11-21. PMID:16112091. |
in contrast, under conditions of maternal deprivation stress, the knockout mouse showed a significant decrease in post-tetanic potentiation and ltp induction and a significant impairment in morris water maze test compared to the wild-type mouse, suggesting that complexin ii plays a significant role in neurotransmitter release and synaptic plasticity under this pathological condition. |
2005-11-21 |
2023-08-12 |
mouse |
| Kimberly J Harms, Ann Marie Crai. Synapse composition and organization following chronic activity blockade in cultured hippocampal neurons. The Journal of comparative neurology. vol 490. issue 1. 2005-11-07. PMID:16041714. |
activity plays multiple roles in the expression of synaptic plasticity, and has been shown to regulate the localization of both neurotransmitter receptors and downstream signaling machinery. |
2005-11-07 |
2023-08-12 |
Not clear |
| Shih-Jen Tsa. Possible involvement of brain-derived neurotrophic factor in the antinociceptive effect of antidepressants in neuropathic pain. Medical hypotheses. vol 65. issue 3. 2005-10-27. PMID:15905042. |
brain-derived neurotrophic factor (bdnf), a member of the neurotrophic factor family, can modulate synaptic plasticity and neurotransmitter release across multiple neurotransmitter systems. |
2005-10-27 |
2023-08-12 |
human |
| Robert K McNamara, Rifat J Hussain, Erica J Simon, Deborah J Stumpo, Perry J Blackshear, Ted Abel, Robert H Leno. Effect of myristoylated alanine-rich C kinase substrate (MARCKS) overexpression on hippocampus-dependent learning and hippocampal synaptic plasticity in MARCKS transgenic mice. Hippocampus. vol 15. issue 5. 2005-09-07. PMID:15889447. |
schaffer collateral paired-pulse facilitation, input-output responses, and ltp did not differ between tg+ and tg- mice, indicating that neurotransmitter release, short-term, and long-term synaptic plasticity are not impaired by marcks overexpression. |
2005-09-07 |
2023-08-12 |
mouse |
| Syed I A Zaidi, Anjum Jafri, Toye Doggett, Musa A Haxhi. Airway-related vagal preganglionic neurons express brain-derived neurotrophic factor and TrkB receptors: implications for neuronal plasticity. Brain research. vol 1044. issue 2. 2005-07-18. PMID:15885212. |
recent evidence indicates that brain-derived neurotrophic factor (bdnf) is present in neurons and may affect neurotransmitter release, cell excitability, and synaptic plasticity via activation of tyrosine kinase b (trkb) receptors. |
2005-07-18 |
2023-08-12 |
Not clear |
| P García-Junco-Clemente, P Linares-Clemente, R Fernández-Chacó. Active zones for presynaptic plasticity in the brain. Molecular psychiatry. vol 10. issue 2. 2005-07-15. PMID:15630409. |
recent investigations on the molecular mechanisms of neurotransmitter release modulation in short- and long-term synaptic plasticity in central synapses give a preponderant role to active zone proteins as munc-13 and rim1-alpha, and point toward the maturation process of synaptic vesicles prior to ca(2+)-dependent fusion as a key regulatory step of presynaptic plasticity. |
2005-07-15 |
2023-08-12 |
Not clear |
| Nikita Gamper, Vitaliy Reznikov, Yoichi Yamada, Jian Yang, Mark S Shapir. Phosphatidylinositol [correction] 4,5-bisphosphate signals underlie receptor-specific Gq/11-mediated modulation of N-type Ca2+ channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 48. 2005-07-12. PMID:15574748. |
modulation of voltage-gated ca2+ channels via g-protein-coupled receptors is a prime mechanism regulating neurotransmitter release and synaptic plasticity. |
2005-07-12 |
2023-08-12 |
Not clear |
| Joie A Bernard-Trifilo, Enikö A Kramár, Reidun Torp, Ching-Yi Lin, Eduardo A Pineda, Gary Lynch, Christine M Gal. Integrin signaling cascades are operational in adult hippocampal synapses and modulate NMDA receptor physiology. Journal of neurochemistry. vol 93. issue 4. 2005-07-05. PMID:15857387. |
these results provide the first evidence that, in adult brain, synaptic integrins activate local kinase cascades with potent effects on the operation of nearby neurotransmitter receptors implicated in synaptic plasticity. |
2005-07-05 |
2023-08-12 |
rat |
| Achim Schmidtko, Domenico Del Turco, Ovidiu Coste, Corina Ehnert, Ellen Niederberger, Peter Ruth, Thomas Deller, Gerd Geisslinger, Irmgard Tegede. Essential role of the synaptic vesicle protein synapsin II in formalin-induced hyperalgesia and glutamate release in the spinal cord. Pain. vol 115. issue 1-2. 2005-06-28. PMID:15836980. |
the synaptic vesicle protein synapsin ii plays an important role in the regulation of neurotransmitter release and synaptic plasticity. |
2005-06-28 |
2023-08-12 |
mouse |
| Xuelin Lou, Volker Scheuss, Ralf Schneggenburge. Allosteric modulation of the presynaptic Ca2+ sensor for vesicle fusion. Nature. vol 435. issue 7041. 2005-06-23. PMID:15917809. |
neurotransmitter release is triggered by an increase in the cytosolic ca2+ concentration ([ca2+]i), but it is unknown whether the ca2+-sensitivity of vesicle fusion is modulated during synaptic plasticity. |
2005-06-23 |
2023-08-12 |
Not clear |
| Claus Normann, Kristin Clar. Selective modulation of Ca(2+) influx pathways by 5-HT regulates synaptic long-term plasticity in the hippocampus. Brain research. vol 1037. issue 1-2. 2005-06-16. PMID:15777768. |
in patch-clamp experiments on hippocampal brain slices, we tested the modulation of different forms of synaptic plasticity by the neurotransmitter serotonin (5-ht) which is known to inhibit high-voltage activated ca(2+) channels. |
2005-06-16 |
2023-08-12 |
human |
| Steven J Coope. Endocannabinoids and food consumption: comparisons with benzodiazepine and opioid palatability-dependent appetite. European journal of pharmacology. vol 500. issue 1-3. 2005-06-14. PMID:15464019. |
the endocannabinoid system consists of several endogenous lipids, including anandamide and 2-arachidonoyl-glycerol (2-ag), and constitute a retrograde signalling system, which modulates neurotransmitter release and synaptic plasticity. |
2005-06-14 |
2023-08-12 |
human |
| Ying Wu, Fumiko Kawasaki, Richard W Ordwa. Properties of short-term synaptic depression at larval neuromuscular synapses in wild-type and temperature-sensitive paralytic mutants of Drosophila. Journal of neurophysiology. vol 93. issue 5. 2005-06-13. PMID:15845998. |
these findings reveal novel properties of short-term synaptic depression and suggest that complementary genetic analysis of larval and adult neuromuscular synapses will further define the in vivo mechanisms of neurotransmitter release and short-term synaptic plasticity. |
2005-06-13 |
2023-08-12 |
drosophila_melanogaster |