| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ian W Jones, Jacques Barik, Michael J O'Neill, Susan Wonnacot. Alpha bungarotoxin-1.4 nm gold: a novel conjugate for visualising the precise subcellular distribution of alpha 7* nicotinic acetylcholine receptors. Journal of neuroscience methods. vol 134. issue 1. 2004-05-25. PMID:15102504. |
alpha 7 subunit-containing nicotinic acetylcholine receptors (alpha7* nachr) are involved in a variety of functions in the mammalian brain, including modulating neurotransmitter release and synaptic plasticity. |
2004-05-25 |
2023-08-12 |
rat |
| Leonard Khiroug, Rashid Giniatullin, Rebecca C Klein, Dmitriy Fayuk, Jerrel L Yake. Functional mapping and Ca2+ regulation of nicotinic acetylcholine receptor channels in rat hippocampal CA1 neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 27. 2003-11-04. PMID:14534236. |
diverse subtypes of nicotinic acetylcholine receptors (nachrs), including fast-desensitizing alpha7-containing receptors thought to be ca2+-permeable, are expressed in the cns, where they appear to regulate cognitive processing and synaptic plasticity. |
2003-11-04 |
2023-08-12 |
rat |
| Diego Centonze, Paolo Gubellini, Antonio Pisani, Giorgio Bernardi, Paolo Calabres. Dopamine, acetylcholine and nitric oxide systems interact to induce corticostriatal synaptic plasticity. Reviews in the neurosciences. vol 14. issue 3. 2003-10-23. PMID:14513864. |
dopamine, acetylcholine and nitric oxide systems interact to induce corticostriatal synaptic plasticity. |
2003-10-23 |
2023-08-12 |
Not clear |
| Lingke Zhao, Yen-Ping Kuo, Andrew A George, Jian-Hong Peng, Madhuri Singh Purandare, Katherine M Schroeder, Ronald J Lukas, Jie W. Functional properties of homomeric, human alpha 7-nicotinic acetylcholine receptors heterologously expressed in the SH-EP1 human epithelial cell line. The Journal of pharmacology and experimental therapeutics. vol 305. issue 3. 2003-07-07. PMID:12626641. |
alpha 7-nicotinic acetylcholine receptors (alpha 7-nachrs) are broadly distributed in the central nervous system, where they play important roles in chemical and electrical signaling, and perhaps in neurite outgrowth, synaptic plasticity, and neuronal death/survival. |
2003-07-07 |
2023-08-12 |
human |
| K M Frick, S M Fernandez, S C Bulinsk. Estrogen replacement improves spatial reference memory and increases hippocampal synaptophysin in aged female mice. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421621. |
the results suggest that: (1) estrogen can profoundly improve spatial reference memory in aged females, and (2) this improvement may be related to increased hippocampal synaptic plasticity, but not modulation of the synthetic enzymes for acetylcholine and gaba. |
2003-01-23 |
2023-08-12 |
mouse |
| Diego Centonze, Maddalena Napolitano, Emilia Saulle, Paolo Gubellini, Barbara Picconi, Alessandro Martorana, Antonio Pisani, Alberto Gulino, Giorgio Bernardi, Paolo Calabres. Tissue plasminogen activator is required for corticostriatal long-term potentiation. The European journal of neuroscience. vol 16. issue 4. 2002-11-22. PMID:12270047. |
disruption of tpa gene prevented corticostriatal long-term potentiation, an nmda-dependent form of synaptic plasticity requiring the stimulation of both dopamine and acetylcholine receptors. |
2002-11-22 |
2023-08-12 |
mouse |
| Jeffrey M Greenwood, Michael Draguno. Muscarinic receptor-mediated phosphorylation of cyclic AMP response element binding protein in human neuroblastoma cells. Journal of neurochemistry. vol 82. issue 2. 2002-08-06. PMID:12124440. |
this study describes the effect of signalling through muscarinic acetylcholine receptors on two transcription factors implicated in long-term synaptic plasticity and memory formation, egr1 and the cyclic amp response element binding protein (creb). |
2002-08-06 |
2023-08-12 |
human |
| Emanuele Pesavento, Simona Capsoni, Luciano Domenici, Antonino Cattane. Acute cholinergic rescue of synaptic plasticity in the neurodegenerating cortex of anti-nerve-growth-factor mice. The European journal of neuroscience. vol 15. issue 6. 2002-06-12. PMID:11918663. |
a local, acute increase in the availability of acetylcholine rescues these synaptic plasticity deficits, thus indicating that a cholinergic system mediates the impairment of cortical plasticity at this early stage of the neurodegenerative process triggered by ngf neutralization. |
2002-06-12 |
2023-08-12 |
mouse |
| John G Partridge, Subbu Apparsundaram, Greg A Gerhardt, Jennifer Ronesi, David M Lovinge. Nicotinic acetylcholine receptors interact with dopamine in induction of striatal long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 7. 2002-04-08. PMID:11923419. |
dopamine release is modulated by activation of nicotinic receptors in the dorsal striatum, and activation of nicotinic receptors during high-frequency synaptic activation appears to be capable of interacting with dopaminergic actions that lead to striatal ltd. our results suggest that stimulation of mechanisms involved in striatal synaptic plasticity is an important role for striatal nicotinic acetylcholine receptors and that these mechanisms may contribute to the enhancement of learning and habit formation produced by nicotine intake. |
2002-04-08 |
2023-08-12 |
Not clear |
| H von der Kammer, C Demiralay, B Andresen, C Albrecht, M Mayhaus, R M Nitsc. Regulation of gene expression by muscarinic acetylcholine receptors. Biochemical Society symposium. issue 67. 2001-12-14. PMID:11447829. |
in the brain, muscarinic acetylcholine receptors (machrs) are involved in higher cognitive functions including synaptic plasticity and memory. |
2001-12-14 |
2023-08-12 |
Not clear |
| D Ji, R Lape, J A Dan. Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity. Neuron. vol 31. issue 1. 2001-08-30. PMID:11498056. |
induction of synaptic plasticity, arising via generally accepted mechanisms, is modulated by nicotinic acetylcholine receptors. |
2001-08-30 |
2023-08-12 |
mouse |
| D D Rasmusso. The role of acetylcholine in cortical synaptic plasticity. Behavioural brain research. vol 115. issue 2. 2000-10-19. PMID:11000421. |
the role of acetylcholine in cortical synaptic plasticity. |
2000-10-19 |
2023-08-12 |
Not clear |
| D D Rasmusso. The role of acetylcholine in cortical synaptic plasticity. Behavioural brain research. vol 115. issue 2. 2000-10-19. PMID:11000421. |
this review examines the role of acetylcholine in synaptic plasticity in archi-, paleo- and neocortex. |
2000-10-19 |
2023-08-12 |
Not clear |
| D D Rasmusso. The role of acetylcholine in cortical synaptic plasticity. Behavioural brain research. vol 115. issue 2. 2000-10-19. PMID:11000421. |
this review will examine the mechanisms whereby acetylcholine might induce synaptic plasticity. |
2000-10-19 |
2023-08-12 |
Not clear |
| C Albrecht, H von Der Kammer, M Mayhaus, J Klaudiny, M Schweizer, R M Nitsc. Muscarinic acetylcholine receptors induce the expression of the immediate early growth regulatory gene CYR61. The Journal of biological chemistry. vol 275. issue 37. 2000-10-13. PMID:10852911. |
in brain, muscarinic acetylcholine receptors (machrs) modulate neuronal functions including long term potentiation and synaptic plasticity in neuronal circuits that are involved in learning and memory formation. |
2000-10-13 |
2023-08-12 |
human |
| C Mathis, H Meziane, A Ungere. [Models for the study of memory and neurosteroids]. Journal de la Societe de biologie. vol 193. issue 3. 1999-11-23. PMID:10542961. |
in addition, these two neurosteroids facilitate the release of acetylcholine and modulate synaptic plasticity phenomena in cerebral structures, such as the hippocampus, known to play a role in learning and memory processes. |
1999-11-23 |
2023-08-12 |
Not clear |
| T Nishizaki, T Nomura, T Matsuoka, G Enikolopov, K Sumikaw. Arachidonic acid induces a long-lasting facilitation of hippocampal synaptic transmission by modulating PKC activity and nicotinic ACh receptors. Brain research. Molecular brain research. vol 69. issue 2. 1999-08-03. PMID:10366747. |
the present study was conducted to understand the effect of arachidonic acid on nicotinic acetylcholine (ach) receptor-mediated synaptic plasticity. |
1999-08-03 |
2023-08-12 |
xenopus_laevis |
| V B Aramakis, R Metherat. Nicotine selectively enhances NMDA receptor-mediated synaptic transmission during postnatal development in sensory neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 20. 1998-10-23. PMID:9763491. |
the neurotransmitters acetylcholine (ach) and glutamate have been separately implicated in synaptic plasticity during development of sensory neocortex. |
1998-10-23 |
2023-08-12 |
rat |
| G Hess, R Krawczy. Cholinergic modulation of synaptic transmission in horizontal connections of rat motor cortex. Acta neurobiologiae experimentalis. vol 56. issue 4. 1997-03-18. PMID:9033122. |
the results indicate that endogenous acetylcholine may modulate excitatory synaptic transmission in horizontal connections of rat motor cortex, most likely by acting upon m1 receptors located presynaptically on glutamatergic terminals, and may contribute both to information processing and synaptic plasticity within the motor cortex. |
1997-03-18 |
2023-08-12 |
rat |