| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Saeed Sadigh-Eteghad, Alireza Majdi, Javad Mahmoudi, Samad E J Golzari, Mahnaz Taleb. Astrocytic and microglial nicotinic acetylcholine receptors: an overlooked issue in Alzheimer's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 123. issue 12. 2018-01-29. PMID:27262818. |
in addition, glial nicotinic acetylcholine receptors (nachrs) play a role in ad-related phenomena, such as neuron survival, synaptic plasticity, and memory. |
2018-01-29 |
2023-08-13 |
Not clear |
| Ruud Zwart, Hannah Reed, Emanuele She. Oxotremorine-M potentiates NMDA receptors by muscarinic receptor dependent and independent mechanisms. Biochemical and biophysical research communications. vol 495. issue 1. 2018-01-05. PMID:29127015. |
muscarinic acetylcholine m1 receptors play an important role in synaptic plasticity in the hippocampus and cortex. |
2018-01-05 |
2023-08-13 |
human |
| Ruud Zwart, Hannah Reed, Emanuele She. Oxotremorine-M potentiates NMDA receptors by muscarinic receptor dependent and independent mechanisms. Biochemical and biophysical research communications. vol 495. issue 1. 2018-01-05. PMID:29127015. |
potentiation of nmda receptors as a consequence of muscarinic acetylcholine m1 receptor activation is a crucial event mediating the cholinergic modulation of synaptic plasticity, which is a cellular mechanism for learning and memory. |
2018-01-05 |
2023-08-13 |
human |
| Morten S Thomsen, Maria Arvaniti, Majbrit M Jensen, Mikhail A Shulepko, Dmitry A Dolgikh, Lars H Pinborg, Wolfgang Härtig, Ekaterina N Lyukmanova, Jens D Mikkelse. Lynx1 and Aβ1-42 bind competitively to multiple nicotinic acetylcholine receptor subtypes. Neurobiology of aging. vol 46. 2017-09-28. PMID:27460145. |
lynx1 regulates synaptic plasticity in the brain by regulating nicotinic acetylcholine receptors (nachrs). |
2017-09-28 |
2023-08-13 |
mouse |
| Natasja M W J de Bruin, Chris G Krus. 5-HT6 Receptor Antagonists: Potential Efficacy for the Treatment of Cognitive Impairment in Schizophrenia. Current pharmaceutical design. vol 21. issue 26. 2016-06-03. PMID:26044973. |
5-ht6r antagonists decrease gaba release and gabaergic interneuron excitability, which subsequently disinhibits glutamate and/or acetylcholine release and results in enhancement of synaptic plasticity. |
2016-06-03 |
2023-08-13 |
Not clear |
| J N Berry, S E Engle, J M McIntosh, R M Drena. α6-Containing nicotinic acetylcholine receptors in midbrain dopamine neurons are poised to govern dopamine-mediated behaviors and synaptic plasticity. Neuroscience. vol 304. 2016-05-24. PMID:26210579. |
α6-containing nicotinic acetylcholine receptors in midbrain dopamine neurons are poised to govern dopamine-mediated behaviors and synaptic plasticity. |
2016-05-24 |
2023-08-13 |
mouse |
| Henry G S Martin, Axel Bernabeu, Olivier Lassalle, Clément Bouille, Corinne Beurrier, Anne-Laure Pelissier-Alicot, Olivier J Manzon. Endocannabinoids Mediate Muscarinic Acetylcholine Receptor-Dependent Long-Term Depression in the Adult Medial Prefrontal Cortex. Frontiers in cellular neuroscience. vol 9. 2015-12-09. PMID:26648844. |
muscarinic acetylcholine receptors (machr) in the pfc can induce synaptic plasticity, but the underlying mechanisms remain either opaque or unresolved. |
2015-12-09 |
2023-08-13 |
mouse |
| Maria Grazia Giovannini, Daniele Lana, Giancarlo Pepe. The integrated role of ACh, ERK and mTOR in the mechanisms of hippocampal inhibitory avoidance memory. Neurobiology of learning and memory. vol 119. 2015-12-08. PMID:25595880. |
it has been shown that co-activation of muscarinic acetylcholine receptors and β-adrenergic receptors facilitates the conversion of short term to long term synaptic plasticity through an erk- and mtor-dependent mechanism which requires translation initiation. |
2015-12-08 |
2023-08-13 |
Not clear |
| Ulrika Beitnere, Zane Dzirkale, Sergejs Isajevs, Juris Rumaks, Simons Svirskis, Vija Klus. Carnitine congener mildronate protects against stress- and haloperidol-induced impairment in memory and brain protein expression in rats. European journal of pharmacology. vol 745. 2015-08-24. PMID:25446926. |
the present study investigates the efficacy of mildronate, a carnitine congener, to protect stress and haloperidol-induced impairment of memory in rats and the expression of brain protein biomarkers involved in synaptic plasticity, such as brain-derived neurotrophic factor (bdnf), acetylcholine esterase and glutamate decarboxylase 67 (gad67). |
2015-08-24 |
2023-08-13 |
rat |
| Valentina Di Liberto, Giuseppa Mudo, Kjell Fuxe, Natale Belluard. Interactions between cholinergic and fibroblast growth factor receptors in brain trophism and plasticity. Current protein & peptide science. vol 15. issue 7. 2015-06-01. PMID:25175454. |
acetylcholine, acting on both nicotinic receptors (nachrs) and muscarinic receptors (machrs), plays a role in the regulation of synaptic plasticity, being involved in the regulation of cellular processes and cognitive functions, such as learning, memory and attention. |
2015-06-01 |
2023-08-13 |
Not clear |
| Akira Oda, Hidekazu Tanak. Activities of nicotinic acetylcholine receptors modulate neurotransmission and synaptic architecture. Neural regeneration research. vol 9. issue 24. 2015-02-06. PMID:25657733. |
acetylcholine transduces signals through muscarinic and nicotinic acetylcholine receptors, both of which influence synaptic plasticity and cognition. |
2015-02-06 |
2023-08-13 |
Not clear |
| Xing Lin, Zhongshi Huang, Xiaoyu Chen, Yanping Rong, Shijun Zhang, Yang Jiao, Quanfang Huang, Renbin Huan. Protective effect of Millettia pulchra polysaccharide on cognitive impairment induced by D-galactose in mice. Carbohydrate polymers. vol 101. 2014-08-19. PMID:24299809. |
furthermore, our results also showed that pmp markedly reduced the content and deposition of β-amyloid peptide, improved the dysfunction of synaptic plasticity, increased the levels of acetylcholine, but decreased cholinesterase activity. |
2014-08-19 |
2023-08-12 |
mouse |
| P J Banks, E C Warburton, M W Brown, Z I Bashi. Mechanisms of synaptic plasticity and recognition memory in the perirhinal cortex. Progress in molecular biology and translational science. vol 122. 2014-07-31. PMID:24484702. |
we describe how antagonism of different glutamate and acetylcholine receptors, inhibition of nitric oxide synthase, inhibition of creb phosphorylation, and interfering with glutamate ampa receptor internalization can produce deficits in synaptic plasticity in vitro. |
2014-07-31 |
2023-08-12 |
Not clear |
| Shan He, Ya-Xian Wang, Ronald S Petralia, Stephan D Brenowit. Cholinergic modulation of large-conductance calcium-activated potassium channels regulates synaptic strength and spine calcium in cartwheel cells of the dorsal cochlear nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 15. 2014-06-16. PMID:24719104. |
acetylcholine is a neuromodulatory transmitter that controls synaptic plasticity and sensory processing in many brain regions. |
2014-06-16 |
2023-08-13 |
mouse |
| Daniel J Miller, Elizabeth P Lackey, Troy A Hackett, Jon H Kaa. Development of myelination and cholinergic innervation in the central auditory system of a prosimian primate (Otolemur garnetti). The Journal of comparative neurology. vol 521. issue 16. 2014-06-11. PMID:23749337. |
acetylcholine (ach) is a neurotransmitter critical to normal brain function by regulating synaptic plasticity associated with attention and learning. |
2014-06-11 |
2023-08-12 |
Not clear |
| Lorenzo Rinaldo, Christian Hanse. Muscarinic acetylcholine receptor activation blocks long-term potentiation at cerebellar parallel fiber-Purkinje cell synapses via cannabinoid signaling. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 27. 2013-09-26. PMID:23776234. |
muscarinic acetylcholine receptors (machrs) are known to modulate synaptic plasticity in various brain areas. |
2013-09-26 |
2023-08-12 |
mouse |
| Abu Syed Md Anisuzzaman, Junsuke Uwada, Takayoshi Masuoka, Hatsumi Yoshiki, Matomo Nishio, Yuji Ikegaya, Naoya Takahashi, Norio Matsuki, Yasuhisa Fujibayashi, Yoshiharu Yonekura, Toshihiko Momiyama, Ikunobu Muramats. Novel contribution of cell surface and intracellular M1-muscarinic acetylcholine receptors to synaptic plasticity in hippocampus. Journal of neurochemistry. vol 126. issue 3. 2013-09-20. PMID:23678982. |
novel contribution of cell surface and intracellular m1-muscarinic acetylcholine receptors to synaptic plasticity in hippocampus. |
2013-09-20 |
2023-08-12 |
mouse |
| Leonor M Teles-Grilo Ruivo, Jack R Mello. Cholinergic modulation of hippocampal network function. Frontiers in synaptic neuroscience. vol 5. 2013-08-05. PMID:23908628. |
here, we review the organization of septohippocampal cholinergic projections and hippocampal acetylcholine receptors as well as the role of cholinergic transmission in modulating cellular excitability, synaptic plasticity, and rhythmic network oscillations. |
2013-08-05 |
2023-08-12 |
Not clear |
| Vincent Douchamps, Ali Jeewajee, Pam Blundell, Neil Burgess, Colin Leve. Evidence for encoding versus retrieval scheduling in the hippocampus by theta phase and acetylcholine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 20. 2013-08-02. PMID:23678113. |
two solutions have been proposed for hippocampal region ca1: (1) acetylcholine, released in novelty, selectively suppresses excitatory projections to ca1 from ca3 (mediating the products of retrieval), while sparing entorhinal inputs (mediating novel sensory information) and (2) encoding preferentially occurs at the pyramidal-layer theta peak, coincident with input from entorhinal cortex, and retrieval occurs at the trough, coincident with input from ca3, consistent with theta phase-dependent synaptic plasticity. |
2013-08-02 |
2023-08-12 |
rat |
| Steven A Connor, Sabyasachi Maity, Birbickram Roy, Declan W Ali, Peter V Nguye. Conversion of short-term potentiation to long-term potentiation in mouse CA1 by coactivation of β-adrenergic and muscarinic receptors. Learning & memory (Cold Spring Harbor, N.Y.). vol 19. issue 11. 2013-04-24. PMID:23077334. |
the brain can boost synaptic plasticity through the secretion of neuromodulatory substances, including acetylcholine and noradrenaline. |
2013-04-24 |
2023-08-12 |
mouse |