| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Leonor M Teles-Grilo Ruivo, Jack R Mello. Cholinergic modulation of hippocampal network function. Frontiers in synaptic neuroscience. vol 5. 2013-08-05. PMID:23908628. |
here, we review the organization of septohippocampal cholinergic projections and hippocampal acetylcholine receptors as well as the role of cholinergic transmission in modulating cellular excitability, synaptic plasticity, and rhythmic network oscillations. |
2013-08-05 |
2023-08-12 |
Not clear |
| Vincent Douchamps, Ali Jeewajee, Pam Blundell, Neil Burgess, Colin Leve. Evidence for encoding versus retrieval scheduling in the hippocampus by theta phase and acetylcholine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 20. 2013-08-02. PMID:23678113. |
two solutions have been proposed for hippocampal region ca1: (1) acetylcholine, released in novelty, selectively suppresses excitatory projections to ca1 from ca3 (mediating the products of retrieval), while sparing entorhinal inputs (mediating novel sensory information) and (2) encoding preferentially occurs at the pyramidal-layer theta peak, coincident with input from entorhinal cortex, and retrieval occurs at the trough, coincident with input from ca3, consistent with theta phase-dependent synaptic plasticity. |
2013-08-02 |
2023-08-12 |
rat |
| Steven A Connor, Sabyasachi Maity, Birbickram Roy, Declan W Ali, Peter V Nguye. Conversion of short-term potentiation to long-term potentiation in mouse CA1 by coactivation of β-adrenergic and muscarinic receptors. Learning & memory (Cold Spring Harbor, N.Y.). vol 19. issue 11. 2013-04-24. PMID:23077334. |
the brain can boost synaptic plasticity through the secretion of neuromodulatory substances, including acetylcholine and noradrenaline. |
2013-04-24 |
2023-08-12 |
mouse |
| Marina R Picciotto, Michael J Higley, Yann S Mineu. Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior. Neuron. vol 76. issue 1. 2012-12-10. PMID:23040810. |
acetylcholine in the brain alters neuronal excitability, influences synaptic transmission, induces synaptic plasticity, and coordinates firing of groups of neurons. |
2012-12-10 |
2023-08-12 |
Not clear |
| Etsuko Suzuki, Takashi Okad. Stratum oriens stimulation-evoked modulation of hippocampal long-term potentiation involves the activation of muscarinic acetylcholine receptors and the inhibition of Kv7/M potassium ion channels. The European journal of neuroscience. vol 36. issue 1. 2012-11-19. PMID:22639893. |
acetylcholine is considered to be an endogenous modulator of hippocampal neurotransmission and synaptic plasticity. |
2012-11-19 |
2023-08-12 |
rat |
| Etsuko Suzuki, Takashi Okad. Stratum oriens stimulation-evoked modulation of hippocampal long-term potentiation involves the activation of muscarinic acetylcholine receptors and the inhibition of Kv7/M potassium ion channels. The European journal of neuroscience. vol 36. issue 1. 2012-11-19. PMID:22639893. |
the activation of muscarinic acetylcholine receptors (machrs) reportedly enhances hippocampal synaptic plasticity, which plays an important role in memory function; however, the mechanism by which it enhances synaptic plasticity remains unclear. |
2012-11-19 |
2023-08-12 |
rat |
| C E Stelly, J Cronin, J M Daniel, L A Schrade. Long-term oestradiol treatment enhances hippocampal synaptic plasticity that is dependent on muscarinic acetylcholine receptors in ovariectomised female rats. Journal of neuroendocrinology. vol 24. issue 6. 2012-09-24. PMID:22313316. |
long-term oestradiol treatment enhances hippocampal synaptic plasticity that is dependent on muscarinic acetylcholine receptors in ovariectomised female rats. |
2012-09-24 |
2023-08-12 |
rat |
| Milos M Petrovic, Jakub Nowacki, Valeria Olivo, Krasimira Tsaneva-Atanasova, Andrew D Randall, Jack R Mello. Inhibition of post-synaptic Kv7/KCNQ/M channels facilitates long-term potentiation in the hippocampus. PloS one. vol 7. issue 2. 2012-07-31. PMID:22348007. |
activation of muscarinic acetylcholine receptors (machr) facilitates the induction of synaptic plasticity and enhances cognitive function. |
2012-07-31 |
2023-08-12 |
rat |
| Tomas Ondrejcak, Qinwen Wang, James N C Kew, David J Virley, Neil Upton, Roger Anwyl, Michael J Rowa. Activation of α7 nicotinic acetylcholine receptors persistently enhances hippocampal synaptic transmission and prevents Aß-mediated inhibition of LTP in the rat hippocampus. European journal of pharmacology. vol 677. issue 1-3. 2012-05-17. PMID:22200627. |
nicotinic acetylcholine receptors mediate fast cholinergic modulation of glutamatergic transmission and synaptic plasticity. |
2012-05-17 |
2023-08-12 |
rat |
| P Christoph Janiesch, Hanna-Sophie Krüger, Beatrice Pöschel, Ileana L Hanganu-Opat. Cholinergic control in developing prefrontal-hippocampal networks. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 49. 2012-02-02. PMID:22159110. |
during development, acetylcholine modulates neuronal proliferation, differentiation, and synaptic plasticity, yet its contribution to the maturation of cognitive processing resulting from early entrainment of neuronal networks in oscillatory rhythms remains widely unknown. |
2012-02-02 |
2023-08-12 |
rat |
| Benjamin D Drever, Gernot Riedel, Bettina Plat. The cholinergic system and hippocampal plasticity. Behavioural brain research. vol 221. issue 2. 2011-09-09. PMID:21130117. |
consequently, there is ample evidence to suggest the involvement of both nicotinic and muscarinic acetylcholine receptors in the modulation of synaptic plasticity, which is believed to be the molecular correlate of learning and memory. |
2011-09-09 |
2023-08-12 |
Not clear |
| Yanjun Zhao, Thanos Tzounopoulo. Physiological activation of cholinergic inputs controls associative synaptic plasticity via modulation of endocannabinoid signaling. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 9. 2011-05-13. PMID:21368027. |
here, we show that physiological activation of muscarinic acetylcholine receptors (machrs) controls the size and sign of associative long-term synaptic plasticity via interaction with endocannabinoid signaling. |
2011-05-13 |
2023-08-12 |
Not clear |
| Jessica M André, Prescott T Leach, Thomas J Goul. Nicotine ameliorates NMDA receptor antagonist-induced deficits in contextual fear conditioning through high-affinity nicotinic acetylcholine receptors in the hippocampus. Neuropharmacology. vol 60. issue 4. 2011-05-12. PMID:21167848. |
nmda glutamate receptors (nmdars) and nicotinic acetylcholine receptors (nachrs) are both involved in learning and synaptic plasticity. |
2011-05-12 |
2023-08-12 |
mouse |
| Takaaki Nishimoto, Keiichi Kadoyama, Taizo Taniguchi, Masaoki Takano, Mieko Otani, Tooru Nakamura-Hirota, Yabin Lu, Akira Matsumoto, Shogo Matsuyam. Synaptotagmin1 synthesis induced by synaptic plasticity in mouse hippocampus through activation of nicotinic acetylcholine receptors. Neuroscience letters. vol 489. issue 1. 2011-05-02. PMID:21129439. |
synaptotagmin1 synthesis induced by synaptic plasticity in mouse hippocampus through activation of nicotinic acetylcholine receptors. |
2011-05-02 |
2023-08-12 |
mouse |
| Andrew J Giessel, Bernardo L Sabatin. M1 muscarinic receptors boost synaptic potentials and calcium influx in dendritic spines by inhibiting postsynaptic SK channels. Neuron. vol 68. issue 5. 2011-01-18. PMID:21145006. |
acetylcholine release and activation of muscarinic cholinergic receptors (machrs) enhance synaptic plasticity in vitro and cognition and memory in vivo. |
2011-01-18 |
2023-08-12 |
Not clear |
| Jihoon Jo, Gi Hoon Son, Bryony L Winters, Myung Jong Kim, Daniel J Whitcomb, Bryony A Dickinson, Youn-Bok Lee, Kensuke Futai, Mascia Amici, Morgan Sheng, Graham L Collingridge, Kwangwook Ch. Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95. Nature neuroscience. vol 13. issue 10. 2010-10-20. PMID:20852624. |
although muscarinic acetylcholine receptors (machrs) and nmda receptors (nmdars) are important for synaptic plasticity, learning and memory, the manner in which they interact is poorly understood. |
2010-10-20 |
2023-08-12 |
Not clear |
| Phillip R Zoladz, David M Diamon. Linear and non-linear dose-response functions reveal a hormetic relationship between stress and learning. Dose-response : a publication of International Hormesis Society. vol 7. issue 2. 2010-06-10. PMID:19543480. |
we suggest that stress initially enhances hippocampal function, resulting from amygdala-induced excitation of hippocampal synaptic plasticity, as well as the excitatory effects of several neuromodulators, including corticosteroids, norepinephrine, corticotropin-releasing hormone, acetylcholine and dopamine. |
2010-06-10 |
2023-08-12 |
Not clear |
| Wen Si, Xuliang Zhang, Yan Niu, Huiting Yu, Xiaoping Lei, Huanxin Chen, Xiaohua Ca. A novel derivative of xanomeline improves fear cognition in aged mice. Neuroscience letters. vol 473. issue 2. 2010-04-08. PMID:20178835. |
together, these results show that euk1001 can enhance fear cognition and synaptic plasticity via the activation of m1 muscarinic acetylcholine receptors. |
2010-04-08 |
2023-08-12 |
mouse |
| Giuseppina Martella, Annalisa Tassone, Giuseppe Sciamanna, Paola Platania, Dario Cuomo, Maria Teresa Viscomi, Paola Bonsi, Emanuele Cacci, Stefano Biagioni, Alessandro Usiello, Giorgio Bernardi, Nutan Sharma, David G Standaert, Antonio Pisan. Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine. Brain : a journal of neurology. vol 132. issue Pt 9. 2009-12-14. PMID:19641103. |
impairment of bidirectional synaptic plasticity in the striatum of a mouse model of dyt1 dystonia: role of endogenous acetylcholine. |
2009-12-14 |
2023-08-12 |
mouse |
| Giuseppina Martella, Annalisa Tassone, Giuseppe Sciamanna, Paola Platania, Dario Cuomo, Maria Teresa Viscomi, Paola Bonsi, Emanuele Cacci, Stefano Biagioni, Alessandro Usiello, Giorgio Bernardi, Nutan Sharma, David G Standaert, Antonio Pisan. Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine. Brain : a journal of neurology. vol 132. issue Pt 9. 2009-12-14. PMID:19641103. |
since anti-cholinergic drugs are an effective medical therapeutic option for the treatment of human dystonia, we reasoned that an excess in endogenous acetylcholine could underlie the synaptic plasticity impairment. |
2009-12-14 |
2023-08-12 |
mouse |