| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M N Wu, Y X He, F Guo, J S Q. Alpha4beta2 nicotinic acetylcholine receptors are required for the amyloid beta protein-induced suppression of long-term potentiation in rat hippocampal CA1 region in vivo. Brain research bulletin. vol 77. issue 2-3. 2008-10-06. PMID:18602971. |
amyloid beta protein (abeta) is thought to be responsible for the deficit of learning and memory in alzheimer's disease (ad), possibly through interfering with synaptic plasticity such as hippocampal long-term potentiation (ltp). |
2008-10-06 |
2023-08-12 |
rat |
| Neng-Wei Hu, Imelda M Smith, Dominic M Walsh, Michael J Rowa. Soluble amyloid-beta peptides potently disrupt hippocampal synaptic plasticity in the absence of cerebrovascular dysfunction in vivo. Brain : a journal of neurology. vol 131. issue Pt 9. 2008-10-06. PMID:18678563. |
soluble amyloid-beta peptides potently disrupt hippocampal synaptic plasticity in the absence of cerebrovascular dysfunction in vivo. |
2008-10-06 |
2023-08-12 |
rat |
| Giovanni Piccoli, Chiara Verpelli, Noemi Tonna, Stefano Romorini, Massimo Alessio, Angus C Nairn, Angela Bachi, Carlo Sal. Proteomic analysis of activity-dependent synaptic plasticity in hippocampal neurons. Journal of proteome research. vol 6. issue 8. 2008-09-26. PMID:17622166. |
proteomic analysis of activity-dependent synaptic plasticity in hippocampal neurons. |
2008-09-26 |
2023-08-12 |
Not clear |
| Tyler K Best, Madelaine Cho-Clark, Richard J Siarey, Zygmunt Galdzick. Speeding of miniature excitatory post-synaptic currents in Ts65Dn cultured hippocampal neurons. Neuroscience letters. vol 438. issue 3. 2008-09-26. PMID:18490108. |
of these, ts65dn mice show abnormal hippocampal properties including learning and memory deficits, altered synaptic plasticity and irregular dendritic spines. |
2008-09-26 |
2023-08-12 |
mouse |
| Anne Kemp, Denise Manahan-Vaugha. Beta-adrenoreceptors comprise a critical element in learning-facilitated long-term plasticity. Cerebral cortex (New York, N.Y. : 1991). vol 18. issue 6. 2008-09-25. PMID:17906333. |
using electrophysiological recordings of hippocampal responses in freely moving rats during spatial learning, we investigated the role of the beta-adrenoreceptor in schaeffer collateral-ca1 synaptic plasticity. |
2008-09-25 |
2023-08-12 |
rat |
| Anne Kemp, Denise Manahan-Vaugha. Beta-adrenoreceptors comprise a critical element in learning-facilitated long-term plasticity. Cerebral cortex (New York, N.Y. : 1991). vol 18. issue 6. 2008-09-25. PMID:17906333. |
these results suggest that beta-adrenoreceptors may facilitate encoding of spatial information through synaptic plasticity in the hippocampus and that noradrenaline is a key factor in effective information acquisition. |
2008-09-25 |
2023-08-12 |
rat |
| Chih-Hao Yang, Chiung-Chun Huang, Kuei-Sen Hs. Differential roles of basolateral and central amygdala on the effects of uncontrollable stress on hippocampal synaptic plasticity. Hippocampus. vol 18. issue 6. 2008-09-22. PMID:18306298. |
differential roles of basolateral and central amygdala on the effects of uncontrollable stress on hippocampal synaptic plasticity. |
2008-09-22 |
2023-08-12 |
Not clear |
| Chih-Hao Yang, Chiung-Chun Huang, Kuei-Sen Hs. Differential roles of basolateral and central amygdala on the effects of uncontrollable stress on hippocampal synaptic plasticity. Hippocampus. vol 18. issue 6. 2008-09-22. PMID:18306298. |
these findings suggest that bla erk1/2 signaling pathway is critical to mediate the stress effects on hippocampal synaptic plasticity; the activation of cea erk1/2, in contrast, appears to mediate the reversal of stress effects. |
2008-09-22 |
2023-08-12 |
Not clear |
| Andreas T Sørensen, Irene Kanter-Schlifke, Mirjana Carli, Claudia Balducci, Francesco Noe, Matthew J During, Annamaria Vezzani, Merab Kokai. NPY gene transfer in the hippocampus attenuates synaptic plasticity and learning. Hippocampus. vol 18. issue 6. 2008-09-22. PMID:18306304. |
npy gene transfer in the hippocampus attenuates synaptic plasticity and learning. |
2008-09-22 |
2023-08-12 |
rat |
| Andreas T Sørensen, Irene Kanter-Schlifke, Mirjana Carli, Claudia Balducci, Francesco Noe, Matthew J During, Annamaria Vezzani, Merab Kokai. NPY gene transfer in the hippocampus attenuates synaptic plasticity and learning. Hippocampus. vol 18. issue 6. 2008-09-22. PMID:18306304. |
here we show, by electrophysiological recordings in ca1 of the hippocampal formation of rats, that hippocampal npy gene transfer into the intact brain does not affect basal synaptic transmission, but slightly alters short-term synaptic plasticity, most likely via npy y2 receptor-mediated mechanisms. |
2008-09-22 |
2023-08-12 |
rat |
| Andreas T Sørensen, Irene Kanter-Schlifke, Mirjana Carli, Claudia Balducci, Francesco Noe, Matthew J During, Annamaria Vezzani, Merab Kokai. NPY gene transfer in the hippocampus attenuates synaptic plasticity and learning. Hippocampus. vol 18. issue 6. 2008-09-22. PMID:18306304. |
these data provide the first evidence that raav-based gene therapy using npy exerts relative limited effect on synaptic plasticity and learning in the hippocampus, and therefore this approach could be considered as a viable alternative for epilepsy treatment. |
2008-09-22 |
2023-08-12 |
rat |
| Patrick J Mulholland, Ezekiel P Carpenter-Hyland, Matthew C Hearing, Howard C Becker, John J Woodward, L Judson Chandle. Glutamate transporters regulate extrasynaptic NMDA receptor modulation of Kv2.1 potassium channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 35. 2008-09-18. PMID:18753382. |
because nmda-type glutamate receptors are critical regulators of synaptic plasticity, we investigated nmda receptor modulation of kv2.1 channels in rodent hippocampus and cortex. |
2008-09-18 |
2023-08-12 |
mouse |
| Jin-Xia Dai, Hui-Li Han, Meng Tian, Jun Cao, Jian-Bo Xiu, Ning-Ning Song, Ying Huang, Tian-Le Xu, Yu-Qiang Ding, Lin X. Enhanced contextual fear memory in central serotonin-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 33. 2008-09-16. PMID:18695238. |
furthermore, bath application of 5-ht in 5-ht-deficient mice restored foot shock-induced alterations of hippocampal synaptic plasticity. |
2008-09-16 |
2023-08-12 |
mouse |
| Jin-Xia Dai, Hui-Li Han, Meng Tian, Jun Cao, Jian-Bo Xiu, Ning-Ning Song, Ying Huang, Tian-Le Xu, Yu-Qiang Ding, Lin X. Enhanced contextual fear memory in central serotonin-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 33. 2008-09-16. PMID:18695238. |
thus, central 5-ht regulates hippocampus-dependent contextual fear memory, and 5-ht modulation of hippocampal synaptic plasticity may be the underlying mechanism. |
2008-09-16 |
2023-08-12 |
mouse |
| N Ruth Zearfoss, Juan Marcos Alarcon, Pierre Trifilieff, Eric Kandel, Joel D Richte. A molecular circuit composed of CPEB-1 and c-Jun controls growth hormone-mediated synaptic plasticity in the mouse hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 34. 2008-09-16. PMID:18716208. |
a molecular circuit composed of cpeb-1 and c-jun controls growth hormone-mediated synaptic plasticity in the mouse hippocampus. |
2008-09-16 |
2023-08-12 |
mouse |
| N Ruth Zearfoss, Juan Marcos Alarcon, Pierre Trifilieff, Eric Kandel, Joel D Richte. A molecular circuit composed of CPEB-1 and c-Jun controls growth hormone-mediated synaptic plasticity in the mouse hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 34. 2008-09-16. PMID:18716208. |
these results indicate that cpeb-1 control of c-jun mrna translation regulates gh gene expression and resulting downstream signaling events (e.g., synaptic plasticity) in the mouse hippocampus. |
2008-09-16 |
2023-08-12 |
mouse |
| Shigeki Moriguchi, Norifumi Shioda, Feng Han, Toshio Narahashi, Kohji Fukunag. CaM kinase II and protein kinase C activations mediate enhancement of long-term potentiation by nefiracetam in the rat hippocampal CA1 region. Journal of neurochemistry. vol 106. issue 3. 2008-09-15. PMID:18445137. |
to address questions whether nefiracetam affects nmda receptor-dependent synaptic plasticity in the hippocampus, we assessed effects of nefiracetam on nmda receptor-dependent long-term potentiation (ltp) by electrophysiology and ltp-induced phosphorylation of synaptic proteins by immunoblotting analysis. |
2008-09-15 |
2023-08-12 |
rat |
| Delphine Gobert, Lisa Topolnik, Mounia Azzi, Linda Huang, Frédérique Badeaux, Luc Desgroseillers, Wayne S Sossin, Jean-Claude Lacaill. Forskolin induction of late-LTP and up-regulation of 5' TOP mRNAs translation via mTOR, ERK, and PI3K in hippocampal pyramidal cells. Journal of neurochemistry. vol 106. issue 3. 2008-09-15. PMID:18466337. |
synaptic plasticity was studied at schaffer collateral--ca1 pyramidal cell synapses in rat organotypic hippocampal slices. |
2008-09-15 |
2023-08-12 |
rat |
| Toshiya Manab. [Molecular mechanisms for memory formation]. Brain and nerve = Shinkei kenkyu no shinpo. vol 60. issue 7. 2008-09-11. PMID:18646610. |
influx of calcium ions through nmda receptors into the postsynaptic spine triggers biochemical processes associated with synaptic plasticity such as long-term potentiation (ltp), which is believed to underlie memory formation in the cns including the hippocampus and amygdala. |
2008-09-11 |
2023-08-12 |
mouse |
| C Frank, S Rufini, V Tancredi, R Forcina, D Grossi, G D'Arcangel. Cholesterol depletion inhibits synaptic transmission and synaptic plasticity in rat hippocampus. Experimental neurology. vol 212. issue 2. 2008-09-02. PMID:18559278. |
cholesterol depletion inhibits synaptic transmission and synaptic plasticity in rat hippocampus. |
2008-09-02 |
2023-08-12 |
rat |