| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hanna Rosenmann, Nikolaos Grigoriadis, Hila Eldar-Levy, Avi Avital, Lea Rozenstein, Olga Touloumi, Leah Behar, Tamir Ben-Hur, Yosefa Avraham, Eliot Berry, Menahem Segal, Irith Ginzburg, Oded Abramsk. A novel transgenic mouse expressing double mutant tau driven by its natural promoter exhibits tauopathy characteristics. Experimental neurology. vol 212. issue 1. 2008-07-17. PMID:18490011. |
moreover, the tg mice showed a robust synaptic plasticity deficit selectively expressed in a severe impairment in their ability to maintain hippocampal long-term-potentiation (ltp) in response to stimulation of the perforant path, providing evidence that "tau-pathology only" is sufficient to cause this memory and learning-associated deficit. |
2008-07-17 |
2023-08-12 |
mouse |
| Petr Bob, Peter Fedor-Freyberg. Melatonin, consciousness, and traumatic stress. Journal of pineal research. vol 44. issue 4. 2008-07-15. PMID:18410583. |
in this context, recent findings suggest that melatonin could be a potential regulator in the processes that contribute to memory formation, long-term potentiation, and synaptic plasticity in the hippocampus and other brain regions. |
2008-07-15 |
2023-08-12 |
Not clear |
| Carolina Isiegas, Conor McDonough, Ted Huang, Robbert Havekes, Sara Fabian, Long-Jun Wu, Hui Xu, Ming-Gao Zhao, Jae-Ick Kim, Yong-Seok Lee, Hye-Ryeon Lee, Hyoung-Gon Ko, Nuribalhae Lee, Sun-Lim Choi, Jeong-Sik Lee, Hyeon Son, Min Zhuo, Bong-Kiun Kaang, Ted Abe. A novel conditional genetic system reveals that increasing neuronal cAMP enhances memory and retrieval. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 24. 2008-07-10. PMID:18550764. |
we find that activation of this receptor transgenically expressed in mouse forebrain neurons induces a rapid elevation of hippocampal camp levels, facilitates hippocampus synaptic plasticity, and enhances the consolidation and retrieval of fear memory. |
2008-07-10 |
2023-08-12 |
mouse |
| C Fernando Valenzuela, L Donald Partridge, Manuel Mameli, Douglas A Meye. Modulation of glutamatergic transmission by sulfated steroids: role in fetal alcohol spectrum disorder. Brain research reviews. vol 57. issue 2. 2008-07-01. PMID:17597219. |
this developmental form of synaptic plasticity cannot be observed in slices from rats older than postnatal day 6, when presynaptic nmda receptors are no longer expressed in ca1 hippocampal region. |
2008-07-01 |
2023-08-12 |
rat |
| Mari Ogiue-Ikeda, Nobuaki Tanabe, Hideo Mukai, Yasushi Hojo, Gen Murakami, Tomokazu Tsurugizawa, Norio Takata, Tetsuya Kimoto, Suguru Kawat. Rapid modulation of synaptic plasticity by estrogens as well as endocrine disrupters in hippocampal neurons. Brain research reviews. vol 57. issue 2. 2008-07-01. PMID:17822775. |
rapid modulation of synaptic plasticity by estrogens as well as endocrine disrupters in hippocampal neurons. |
2008-07-01 |
2023-08-12 |
Not clear |
| Mari Ogiue-Ikeda, Nobuaki Tanabe, Hideo Mukai, Yasushi Hojo, Gen Murakami, Tomokazu Tsurugizawa, Norio Takata, Tetsuya Kimoto, Suguru Kawat. Rapid modulation of synaptic plasticity by estrogens as well as endocrine disrupters in hippocampal neurons. Brain research reviews. vol 57. issue 2. 2008-07-01. PMID:17822775. |
estrogen modulates memory-related synaptic plasticity not only slowly but also rapidly in the hippocampus. |
2008-07-01 |
2023-08-12 |
Not clear |
| Julian R Keith, Carolina Priester, Mitchell Ferguson, Michael Salling, Aneeka Hancoc. Persistent increases in the pool of doublecortin-expressing neurons in the hippocampus following spatial navigation training. Behavioural brain research. vol 188. issue 2. 2008-06-20. PMID:18199494. |
hippocampal neurons exhibit a high degree of synaptic plasticity while they are in the dcx phase. |
2008-06-20 |
2023-08-12 |
Not clear |
| Daejong Jeon, Inseon Song, William Guido, Karam Kim, Eunjoon Kim, Uhtaek Oh, Hee-Sup Shi. Ablation of Ca2+ channel beta3 subunit leads to enhanced N-methyl-D-aspartate receptor-dependent long term potentiation and improved long term memory. The Journal of biological chemistry. vol 283. issue 18. 2008-06-19. PMID:18339621. |
here, we investigated ca(v)beta3-deficient mice for hippocampus-dependent learning and memory and synaptic plasticity at hippocampal ca3-ca1 synapses. |
2008-06-19 |
2023-08-12 |
mouse |
| Daejong Jeon, Inseon Song, William Guido, Karam Kim, Eunjoon Kim, Uhtaek Oh, Hee-Sup Shi. Ablation of Ca2+ channel beta3 subunit leads to enhanced N-methyl-D-aspartate receptor-dependent long term potentiation and improved long term memory. The Journal of biological chemistry. vol 283. issue 18. 2008-06-19. PMID:18339621. |
our results suggest a possibility that, unrelated to vdccs regulation, ca(v)beta3 negatively regulates the nmdar activity in the hippocampus and thus activity-dependent synaptic plasticity and cognitive behaviors in the mouse. |
2008-06-19 |
2023-08-12 |
mouse |
| Cary L Scheiderer, Caroline C Smith, Eve McCutchen, Portia A McCoy, Erin E Thacker, Krystyna Kolasa, Lynn E Dobrunz, Lori L McMaho. Coactivation of M(1) muscarinic and alpha1 adrenergic receptors stimulates extracellular signal-regulated protein kinase and induces long-term depression at CA3-CA1 synapses in rat hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 20. 2008-06-19. PMID:18480291. |
however, much remains unclear about the precise roles of acetylcholine (ach) and norepinephrine (ne) in hippocampal function, particularly in terms of how interactions between these two transmitter systems might play an important role in synaptic plasticity. |
2008-06-19 |
2023-08-12 |
rat |
| Z A Bortolotto, W W Anderson, J T Isaac, G L Collingridg. Synaptic plasticity in the hippocampal slice preparation. Current protocols in neuroscience. vol Chapter 6. 2008-06-18. PMID:18428512. |
synaptic plasticity in the hippocampal slice preparation. |
2008-06-18 |
2023-08-12 |
Not clear |
| Z A Bortolotto, W W Anderson, J T Isaac, G L Collingridg. Synaptic plasticity in the hippocampal slice preparation. Current protocols in neuroscience. vol Chapter 6. 2008-06-18. PMID:18428512. |
the study of synaptic plasticity often involves the application of standard in vitro electrophysiological techniques to hippocampal slice preparations. |
2008-06-18 |
2023-08-12 |
Not clear |
| Victor A Gault, Christian Hölsche. Protease-resistant glucose-dependent insulinotropic polypeptide agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid. Journal of neurophysiology. vol 99. issue 4. 2008-06-17. PMID:18234983. |
we tested the effects of native gip and the agonist n-acgip on synaptic plasticity [long-term potentiation (ltp)] in the hippocampus [15 nmol, administered intracerebroventricularly (icv)] and report for the first time that both peptides have enhancing effects on ltp. |
2008-06-17 |
2023-08-12 |
Not clear |
| Alexis M Stranahan, Thiruma V Arumugam, Roy G Cutler, Kim Lee, Josephine M Egan, Mark P Mattso. Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons. Nature neuroscience. vol 11. issue 3. 2008-06-16. PMID:18278039. |
rats treated with streptozocin have reduced insulin and show hyperglycemia, increased corticosterone, and impairments in hippocampal neurogenesis, synaptic plasticity and learning. |
2008-06-16 |
2023-08-12 |
mouse |
| Alexis M Stranahan, Thiruma V Arumugam, Roy G Cutler, Kim Lee, Josephine M Egan, Mark P Mattso. Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons. Nature neuroscience. vol 11. issue 3. 2008-06-16. PMID:18278039. |
changes in hippocampal plasticity and function in both models are reversed when normal physiological levels of corticosterone are maintained, suggesting that cognitive impairment in diabetes may result from glucocorticoid-mediated deficits in neurogenesis and synaptic plasticity. |
2008-06-16 |
2023-08-12 |
mouse |
| Feng Liu, Mark Day, Luis C Muñiz, Daniel Bitran, Robert Arias, Raquel Revilla-Sanchez, Steve Grauer, Guoming Zhang, Cody Kelley, Virginia Pulito, Amy Sung, Ronald F Mervis, Rachel Navarra, Warren D Hirst, Peter H Reinhart, Karen L Marquis, Stephen J Moss, Menelas N Pangalos, Nicholas J Brando. Activation of estrogen receptor-beta regulates hippocampal synaptic plasticity and improves memory. Nature neuroscience. vol 11. issue 3. 2008-06-16. PMID:18297067. |
activation of estrogen receptor-beta regulates hippocampal synaptic plasticity and improves memory. |
2008-06-16 |
2023-08-12 |
mouse |
| Feng Liu, Mark Day, Luis C Muñiz, Daniel Bitran, Robert Arias, Raquel Revilla-Sanchez, Steve Grauer, Guoming Zhang, Cody Kelley, Virginia Pulito, Amy Sung, Ronald F Mervis, Rachel Navarra, Warren D Hirst, Peter H Reinhart, Karen L Marquis, Stephen J Moss, Menelas N Pangalos, Nicholas J Brando. Activation of estrogen receptor-beta regulates hippocampal synaptic plasticity and improves memory. Nature neuroscience. vol 11. issue 3. 2008-06-16. PMID:18297067. |
using pharmacological, biochemical and behavioral techniques, we demonstrate that the effects of estrogen on hippocampal synaptic plasticity and memory are mediated through erbeta. |
2008-06-16 |
2023-08-12 |
mouse |
| Feng Liu, Mark Day, Luis C Muñiz, Daniel Bitran, Robert Arias, Raquel Revilla-Sanchez, Steve Grauer, Guoming Zhang, Cody Kelley, Virginia Pulito, Amy Sung, Ronald F Mervis, Rachel Navarra, Warren D Hirst, Peter H Reinhart, Karen L Marquis, Stephen J Moss, Menelas N Pangalos, Nicholas J Brando. Activation of estrogen receptor-beta regulates hippocampal synaptic plasticity and improves memory. Nature neuroscience. vol 11. issue 3. 2008-06-16. PMID:18297067. |
our data suggest that activation of erbeta can regulate hippocampal synaptic plasticity and improve hippocampus-dependent cognition. |
2008-06-16 |
2023-08-12 |
mouse |
| Eric S Guire, Michael C Oh, Thomas R Soderling, Victor A Derkac. Recruitment of calcium-permeable AMPA receptors during synaptic potentiation is regulated by CaM-kinase I. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 23. 2008-06-16. PMID:18524905. |
however, intracellular signaling pathways that recruit synaptic cp-ampars are unknown, and involvement of cp-ampars in hippocampal region ca1 synaptic plasticity is controversial. |
2008-06-16 |
2023-08-12 |
Not clear |
| Danielle L Champagne, Rosemary C Bagot, Felisa van Hasselt, Ger Ramakers, Michael J Meaney, E Ronald de Kloet, Marian Joëls, Harm Kruger. Maternal care and hippocampal plasticity: evidence for experience-dependent structural plasticity, altered synaptic functioning, and differential responsiveness to glucocorticoids and stress. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 23. 2008-06-16. PMID:18524909. |
we examined the effects of variation in the frequency of pup lg on morphological, electrophysiological, and behavioral aspects of hippocampal synaptic plasticity under basal and stress-like conditions. |
2008-06-16 |
2023-08-12 |
Not clear |