| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hongwei Yang, Jian Zhang, Richard M Breyer, Chu Che. Altered hippocampal long-term synaptic plasticity in mice deficient in the PGE2 EP2 receptor. Journal of neurochemistry. vol 108. issue 1. 2009-04-08. PMID:19012750. |
our results show that hippocampal long-term synaptic plasticity is impaired in mice deficient in the ep2, suggesting that pge2-ep2 signaling is important for hippocampal long-term synaptic plasticity and cognitive function. |
2009-04-08 |
2023-08-12 |
mouse |
| Andreas T Sørensen, Litsa Nikitidou, Marco Ledri, En-Ju D Lin, Matthew J During, Irene Kanter-Schlifke, Merab Kokai. Hippocampal NPY gene transfer attenuates seizures without affecting epilepsy-induced impairment of LTP. Experimental neurology. vol 215. issue 2. 2009-04-08. PMID:19038255. |
here we report how raav vector-mediated overexpression of npy in the hippocampus affects rapid kindling, and subsequently explore how synaptic plasticity and transmission is affected by kindling and npy overexpression by field recordings in ca1 stratum radiatum of brain slices. |
2009-04-08 |
2023-08-12 |
rat |
| Natasha Solovyova, Peter R Moult, Bogdan Milojkovic, Jeremy J Lambert, Jenni Harve. Bi-directional modulation of fast inhibitory synaptic transmission by leptin. Journal of neurochemistry. vol 108. issue 1. 2009-04-08. PMID:19094063. |
indeed, leptin markedly influences hippocampal excitatory synaptic transmission and synaptic plasticity. |
2009-04-08 |
2023-08-12 |
Not clear |
| Teiko Miyashita, Stepan Kubik, Nahideh Haghighi, Oswald Steward, John F Guzowsk. Rapid activation of plasticity-associated gene transcription in hippocampal neurons provides a mechanism for encoding of one-trial experience. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 4. 2009-04-08. PMID:19176799. |
a critical prerequisite for such function is the ability to readily recruit enduring synaptic plasticity in hippocampal neurons. |
2009-04-08 |
2023-08-12 |
rat |
| Juha Laurén, David A Gimbel, Haakon B Nygaard, John W Gilbert, Stephen M Strittmatte. Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers. Nature. vol 457. issue 7233. 2009-04-07. PMID:19242475. |
anti-prp antibodies prevent amyloid-beta-oligomer binding to prp(c) and rescue synaptic plasticity in hippocampal slices from oligomeric amyloid-beta. |
2009-04-07 |
2023-08-12 |
mouse |
| Suhail Asrar, Yanghong Meng, Zikai Zhou, Zarko Todorovski, Wayne Wenyin Huang, Zhengping Ji. Regulation of hippocampal long-term potentiation by p21-activated protein kinase 1 (PAK1). Neuropharmacology. vol 56. issue 1. 2009-04-02. PMID:18644395. |
these results indicate that pak1 is critical in hippocampal synaptic plasticity via regulating cofilin activity and the actin cytoskeleton. |
2009-04-02 |
2023-08-12 |
mouse |
| Eleni Koutsilieri, Peter Riedere. Excitotoxicity and new antiglutamatergic strategies in Parkinson's disease and Alzheimer's disease. Parkinsonism & related disorders. vol 13 Suppl 3. 2009-04-01. PMID:18267259. |
n-methyl-d-aspartate (nmda) receptors play central roles in a number of physiological processes, including long-term potentiation in the hippocampus, synaptogenesis and synaptic plasticity. |
2009-04-01 |
2023-08-12 |
Not clear |
| Gonzalo Sánchez, Lucas de Oliveira Alvares, María Victoria Oberholzer, Bruna Genro, Jorge Quillfeldt, Jaderson Costa da Costa, Carlos Cerveñansky, Diana Jerusalinsky, Edgar Kornisiu. M4 muscarinic receptors are involved in modulation of neurotransmission at synapses of Schaffer collaterals on CA1 hippocampal neurons in rats. Journal of neuroscience research. vol 87. issue 3. 2009-03-31. PMID:18816796. |
all five subtypes of muscarinic acetylcholine receptors (machr; m(1)-m(5)) are expressed in the hippocampus, where they are involved both in cognitive functions and in synaptic plasticity, such as long-term potentiation (ltp). |
2009-03-31 |
2023-08-12 |
rat |
| R I Westphalen, R S Gomez, H C Hemming. Nicotinic receptor-evoked hippocampal norepinephrine release is highly sensitive to inhibition by isoflurane. British journal of anaesthesia. vol 102. issue 3. 2009-03-20. PMID:19189985. |
activation of hippocampal nachrs stimulates the release of norepinephrine (ne), a neurotransmitter implicated in modulating hippocampal synaptic plasticity. |
2009-03-20 |
2023-08-12 |
Not clear |
| Angela M Wong, Irina Rozovsky, Jason M Arimoto, Yizhou Du, Min Wei, Todd E Morgan, Caleb E Finc. Progesterone influence on neurite outgrowth involves microglia. Endocrinology. vol 150. issue 1. 2009-03-12. PMID:18772232. |
to further understand how p4 modulates synaptic plasticity, we used entorhinal cortex lesions, which induce e2-dependent neurite sprouting in the hippocampus. |
2009-03-12 |
2023-08-12 |
rat |
| Genevieve S Young, James B Kirklan. The role of dietary niacin intake and the adenosine-5'-diphosphate-ribosyl cyclase enzyme CD38 in spatial learning ability: is cyclic adenosine diphosphate ribose the link between diet and behaviour? Nutrition research reviews. vol 21. issue 1. 2009-03-06. PMID:19079853. |
the pyridine nucleotide nad+ is derived from dietary niacin and serves as the substrate for the synthesis of cyclic adp-ribose (cadpr), an intracellular ca signalling molecule that plays an important role in synaptic plasticity in the hippocampus, a region of the brain involved in spatial learning. |
2009-03-06 |
2023-08-12 |
mouse |
| Alexandre Serrano, Richard Robitaille, Jean-Claude Lacaill. Differential NMDA-dependent activation of glial cells in mouse hippocampus. Glia. vol 56. issue 15. 2009-03-05. PMID:18618659. |
in the hippocampus, the nmda receptor is thought to be an important glutamate receptor involved in synaptic plasticity and in memory processes. |
2009-03-05 |
2023-08-12 |
mouse |
| Adam B Barrett, Guy O Billings, Richard G M Morris, Mark C W van Rossu. State based model of long-term potentiation and synaptic tagging and capture. PLoS computational biology. vol 5. issue 1. 2009-02-26. PMID:19148264. |
here we present a biophysical model of synaptic plasticity in the hippocampus that incorporates several key results from experiments on stc. |
2009-02-26 |
2023-08-12 |
Not clear |
| Melanie K Tallent, Neal Varghis, Yuliya Skorobogatko, Lisa Hernandez-Cuebas, Kelly Whelan, David J Vocadlo, Keith Vosselle. In vivo modulation of O-GlcNAc levels regulates hippocampal synaptic plasticity through interplay with phosphorylation. The Journal of biological chemistry. vol 284. issue 1. 2009-02-24. PMID:19004831. |
in vivo modulation of o-glcnac levels regulates hippocampal synaptic plasticity through interplay with phosphorylation. |
2009-02-24 |
2023-08-12 |
mouse |
| Melanie K Tallent, Neal Varghis, Yuliya Skorobogatko, Lisa Hernandez-Cuebas, Kelly Whelan, David J Vocadlo, Keith Vosselle. In vivo modulation of O-GlcNAc levels regulates hippocampal synaptic plasticity through interplay with phosphorylation. The Journal of biological chemistry. vol 284. issue 1. 2009-02-24. PMID:19004831. |
synapsin i and ii are presynaptic proteins that increase synaptic vesicle availability for release when phosphorylated, thus contributing to hippocampal synaptic plasticity. |
2009-02-24 |
2023-08-12 |
mouse |
| Peter R Moult, Bogdan Milojkovic, Jenni Harve. Leptin reverses long-term potentiation at hippocampal CA1 synapses. Journal of neurochemistry. vol 108. issue 3. 2009-02-24. PMID:19054283. |
the hormone leptin crosses the blood brain barrier and regulates numerous neuronal functions, including hippocampal synaptic plasticity. |
2009-02-24 |
2023-08-12 |
Not clear |
| Peter R Moult, Bogdan Milojkovic, Jenni Harve. Leptin reverses long-term potentiation at hippocampal CA1 synapses. Journal of neurochemistry. vol 108. issue 3. 2009-02-24. PMID:19054283. |
these data indicate that leptin reverses hippocampal ltp via a process involving calcineurin-dependent internalization of glur2-lacking ampa receptors which further highlights the key role for this hormone in regulating hippocampal synaptic plasticity and neuronal development. |
2009-02-24 |
2023-08-12 |
Not clear |
| Binith Cheeran, Penelope Talelli, Francesco Mori, Giacomo Koch, Antonio Suppa, Mark Edwards, Henry Houlden, Kailash Bhatia, Richard Greenwood, John C Rothwel. A common polymorphism in the brain-derived neurotrophic factor gene (BDNF) modulates human cortical plasticity and the response to rTMS. The Journal of physiology. vol 586. issue 23. 2009-02-23. PMID:18845611. |
the brain-derived neurotrophic factor gene (bdnf) is one of many genes thought to influence synaptic plasticity in the adult brain and shows a common single nucleotide polymorphism (bdnf val66met) in the normal population that is associated with differences in hippocampal volume and episodic memory. |
2009-02-23 |
2023-08-12 |
human |
| Smita Thakker-Varia, Janet Alde. Neuropeptides in depression: role of VGF. Behavioural brain research. vol 197. issue 2. 2009-02-23. PMID:18983874. |
vgf enhances hippocampal synaptic plasticity as well as neurogenesis in the dentate gyrus but the mechanisms of antidepressant-like actions of vgf in behavioral paradigms are not known. |
2009-02-23 |
2023-08-12 |
Not clear |
| Hsiao-Yun Ku, Yu-Fei Huang, Pei-Hsuan Chao, Chiung-Chun Huang, Kuei-Sen Hs. Neonatal isolation delays the developmental decline of long-term depression in the CA1 region of rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 12. 2009-02-20. PMID:18368035. |
these results suggest a novel role for crf in regulating developmental events in the hippocampus and indicate that although maternal deprivation is stressful for neonate, appropriate neonatal isolation can serve to promote an endocrine state that may regulate the gradual developmental change in the induction rules for synaptic plasticity in the hippocampal ca1 region. |
2009-02-20 |
2023-08-12 |
rat |