| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julie Blanchard, Silvia Bolognin, Muhammad Omar Chohan, Ausma Rabe, Khalid Iqbal, Inge Grundke-Iqba. Rescue of synaptic failure and alleviation of learning and memory impairments in a trisomic mouse model of down syndrome. Journal of neuropathology and experimental neurology. vol 70. issue 12. 2012-02-10. PMID:22082658. |
long-term treatment with peptide 6 enhanced the pool of neural progenitor cells in the hippocampus and increased levels of synaptic proteins crucial for synaptic plasticity. |
2012-02-10 |
2023-08-12 |
mouse |
| Valentina Echeverria, Ross Zeitlin, Sarah Burgess, Sagar Patel, Arghya Barman, Garima Thakur, Magorzota Mamcarz, Li Wang, David B Sattelle, Daniel A Kirschner, Takashi Mori, Roger M Leblanc, Rajeev Prabhakar, Gary W Arendas. Cotinine reduces amyloid-β aggregation and improves memory in Alzheimer's disease mice. Journal of Alzheimer's disease : JAD. vol 24. issue 4. 2012-02-09. PMID:21321389. |
cotinine stimulated akt signaling, including the inhibition of glycogen synthase kinase 3β (gsk3β), which promotes neuronal survival and the synaptic plasticity processes underlying learning and memory in the hippocampus and cortex of wild type and tg6799 ad mice. |
2012-02-09 |
2023-08-12 |
mouse |
| b' Claudia Balducci, Bisan Mehdawy, Lydia Mare, Alessandro Giuliani, Luca Lorenzini, Sandra Sivilia, Luciana Giardino, Laura Calz\\xc3\\xa0, Annamaria Lanzillotta, Ilenia Sarnico, Marina Pizzi, Alessandro Usiello, Arturo R Viscomi, Simone Ottonello, Gino Villetti, Bruno P Imbimbo, Giuseppe Nistic\\xc3\\xb2, Gianluigi Forloni, Robert Nistic\\xc3\\xb. The \\xce\\xb3-secretase modulator CHF5074 restores memory and hippocampal synaptic plasticity in plaque-free Tg2576 mice. Journal of Alzheimer\'s disease : JAD. vol 24. issue 4. 2012-02-09. PMID:21321397.' |
the γ-secretase modulator chf5074 restores memory and hippocampal synaptic plasticity in plaque-free tg2576 mice. |
2012-02-09 |
2023-08-12 |
mouse |
| b' Claudia Balducci, Bisan Mehdawy, Lydia Mare, Alessandro Giuliani, Luca Lorenzini, Sandra Sivilia, Luciana Giardino, Laura Calz\\xc3\\xa0, Annamaria Lanzillotta, Ilenia Sarnico, Marina Pizzi, Alessandro Usiello, Arturo R Viscomi, Simone Ottonello, Gino Villetti, Bruno P Imbimbo, Giuseppe Nistic\\xc3\\xb2, Gianluigi Forloni, Robert Nistic\\xc3\\xb. The \\xce\\xb3-secretase modulator CHF5074 restores memory and hippocampal synaptic plasticity in plaque-free Tg2576 mice. Journal of Alzheimer\'s disease : JAD. vol 24. issue 4. 2012-02-09. PMID:21321397.' |
here, we evaluated the effects of acute and subchronic treatment with chf5074 on contextual and recognition memory and on hippocampal synaptic plasticity in plaque-free tg2576 mice. |
2012-02-09 |
2023-08-12 |
mouse |
| Zhanyong Li, Yiyi Wang, Yongling Xie, Zhuo Yang, Tao Zhan. Protective effects of exogenous hydrogen sulfide on neurons of hippocampus in a rat model of brain ischemia. Neurochemical research. vol 36. issue 10. 2012-02-08. PMID:21603936. |
exogenous h(2)s enhanced synaptic plasticity in the hippocampus of brain-ischemic rats, inhibited the edema around pyramidal neurons and the nuclear shrink induced by ischemia, and promoted the expression of growth-associated protein-43 (gap-43) in the ca1 region of hippocampus post ischemia. |
2012-02-08 |
2023-08-12 |
rat |
| G Guiraudie-Capraz, F A Chaillan, B Truchet, J L Franc, C Mourre, F S Roma. Increase in polysialyltransferase gene expression following LTP in adult rat dentate gyrus. Hippocampus. vol 21. issue 11. 2012-02-07. PMID:20665595. |
psa-ncam plays an important role in synaptic plasticity in the hippocampus. |
2012-02-07 |
2023-08-12 |
rat |
| Patrizia Ambrogini, Stefano Ciuffoli, Davide Lattanzi, Andrea Minelli, Corrado Bucherelli, Elisabetta Baldi, Michele Betti, Riccardo Cuppin. Maternal dietary loads of α-tocopherol differentially influence fear conditioning and spatial learning in adult offspring. Physiology & behavior. vol 104. issue 5. 2012-02-06. PMID:21839761. |
in a previous work, we found that maternal α-tocopherol supplementation affects pkc-mediated cellular signaling and hippocampal synaptic plasticity in developing brain; the latter effect persists in adulthood. |
2012-02-06 |
2023-08-12 |
rat |
| Elias Pavlopoulos, Pierre Trifilieff, Vivien Chevaleyre, Luana Fioriti, Sakellarios Zairis, Andrew Pagano, Gaël Malleret, Eric R Kande. Neuralized1 activates CPEB3: a function for nonproteolytic ubiquitin in synaptic plasticity and memory storage. Cell. vol 147. issue 6. 2012-02-03. PMID:22153079. |
in hippocampal cultures, cpeb3 activated by neuralized1-mediated ubiquitination leads both to the growth of new dendritic spines and to an increase of the glua1 and glua2 subunits of ampa receptors, two cpeb3 targets essential for synaptic plasticity. |
2012-02-03 |
2023-08-12 |
mouse |
| Elias Pavlopoulos, Pierre Trifilieff, Vivien Chevaleyre, Luana Fioriti, Sakellarios Zairis, Andrew Pagano, Gaël Malleret, Eric R Kande. Neuralized1 activates CPEB3: a function for nonproteolytic ubiquitin in synaptic plasticity and memory storage. Cell. vol 147. issue 6. 2012-02-03. PMID:22153079. |
conditional overexpression of neuralized1 similarly increases glua1 and glua2 and the number of spines and functional synapses in the hippocampus and is reflected in enhanced hippocampal-dependent memory and synaptic plasticity. |
2012-02-03 |
2023-08-12 |
mouse |
| Yan Zeng, Miao Tan, Jun Kohyama, Marissa Sneddon, Joseph B Watson, Yi E Sun, Cui-Wei Xi. Epigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 49. 2012-02-02. PMID:22159096. |
here we demonstrated age-dependent deficits in long-term synaptic plasticity and loss of dendritic spines in the hippocampus of aged fisher 344 rats, which were closely associated with reduced histone acetylation, upregulation of histone deacetylase (hdac) 2, and decreased expression of a histone acetyltransferase. |
2012-02-02 |
2023-08-12 |
rat |
| Michael Patterson, Ryohei Yasud. Signalling pathways underlying structural plasticity of dendritic spines. British journal of pharmacology. vol 163. issue 8. 2012-01-31. PMID:21410464. |
imaging studies, mainly in brain slices, have revealed that long-term synaptic plasticity of excitatory synapses in hippocampal neurons is coupled with structural plasticity of dendritic spines, which is thought to be essential for inducing and regulating functional plasticity. |
2012-01-31 |
2023-08-12 |
Not clear |
| Peter van der Sluijs, Casper C Hoogenraa. New insights in endosomal dynamics and AMPA receptor trafficking. Seminars in cell & developmental biology. vol 22. issue 5. 2012-01-26. PMID:21843653. |
the trafficking mechanisms that control the density of synaptic ampa-type glutamate receptors have received significant attention because of their importance for regulating excitatory synaptic transmission and synaptic plasticity in the hippocampus. |
2012-01-26 |
2023-08-12 |
Not clear |
| Hey-Kyoung Lee, Alfredo Kirkwoo. AMPA receptor regulation during synaptic plasticity in hippocampus and neocortex. Seminars in cell & developmental biology. vol 22. issue 5. 2012-01-26. PMID:21856433. |
ampa receptor regulation during synaptic plasticity in hippocampus and neocortex. |
2012-01-26 |
2023-08-12 |
rabbit |
| Hey-Kyoung Lee, Alfredo Kirkwoo. AMPA receptor regulation during synaptic plasticity in hippocampus and neocortex. Seminars in cell & developmental biology. vol 22. issue 5. 2012-01-26. PMID:21856433. |
since then hippocampal synapses have been a key model system to study the mechanisms of different forms of synaptic plasticity. |
2012-01-26 |
2023-08-12 |
rabbit |
| Hey-Kyoung Lee, Alfredo Kirkwoo. AMPA receptor regulation during synaptic plasticity in hippocampus and neocortex. Seminars in cell & developmental biology. vol 22. issue 5. 2012-01-26. PMID:21856433. |
while many of the synaptic plasticity mechanisms uncovered in at the hippocampal synapses apply to synapses across diverse brain regions, there are differences in the mechanisms that often reveal the specific functional requirements of the brain area under study. |
2012-01-26 |
2023-08-12 |
rabbit |
| Hey-Kyoung Lee, Alfredo Kirkwoo. AMPA receptor regulation during synaptic plasticity in hippocampus and neocortex. Seminars in cell & developmental biology. vol 22. issue 5. 2012-01-26. PMID:21856433. |
here we will review ampar regulation underlying synaptic plasticity in hippocampus and neocortex. |
2012-01-26 |
2023-08-12 |
rabbit |
| Atsushi Taked. Zinc signaling in the hippocampus and its relation to pathogenesis of depression. Molecular neurobiology. vol 44. issue 2. 2012-01-23. PMID:21161611. |
hippocampal zn²⁺ signaling may participate in synaptic plasticity such as long-term potentiation and cognitive function. |
2012-01-23 |
2023-08-12 |
Not clear |
| Hardy Hagena, Denise Manahan-Vaugha. Learning-facilitated synaptic plasticity at CA3 mossy fiber and commissural-associational synapses reveals different roles in information processing. Cerebral cortex (New York, N.Y. : 1991). vol 21. issue 11. 2012-01-23. PMID:21493717. |
recently, it has emerged that a special relationship exists between the expression of persistent forms of synaptic plasticity in hippocampal subregions and the encoding of different types of spatial information. |
2012-01-23 |
2023-08-12 |
rat |
| Xiaojie Zhang, Xuebing Liu, Daijun Wang, Haidan Liu, Wei Ha. Conditioned place preference associated with level of palmitoylation of PSD-95 in rat hippocampus and nucleus accumbens. Neuropsychobiology. vol 64. issue 4. 2012-01-20. PMID:21912189. |
psychostimulant-mediated synaptic plasticity in the hippocampus and nucleus accumbens is one of the pathological features of addiction, a disease of learning and memory. |
2012-01-20 |
2023-08-12 |
rat |
| Xiaojie Zhang, Xuebing Liu, Daijun Wang, Haidan Liu, Wei Ha. Conditioned place preference associated with level of palmitoylation of PSD-95 in rat hippocampus and nucleus accumbens. Neuropsychobiology. vol 64. issue 4. 2012-01-20. PMID:21912189. |
our findings suggest that cpp is correlated with the dynamics of psd-95 palmitoylation in rat hippocampus and nucleus accumbens, and could be one of the mechanisms for morphine-dependent synaptic plasticity. |
2012-01-20 |
2023-08-12 |
rat |