| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shelley M Warlow, Sarthak M Singhal, Nick G Hollon, Lauren Faget, Dina S Dowlat, Vivien Zell, Avery C Hunker, Larry S Zweifel, Thomas S Hnask. Mesoaccumbal glutamate neurons drive reward via glutamate release but aversion via dopamine co-release. Neuron. 2023-12-12. PMID:38086374. |
mesoaccumbal glutamate neurons drive reward via glutamate release but aversion via dopamine co-release. |
2023-12-12 |
2023-12-17 |
mouse |
| Ryunosuke Amo, Naoshige Uchida, Mitsuko Watabe-Uchid. Glutamate inputs send prediction error of reward but not negative value of aversive stimuli to dopamine neurons. bioRxiv : the preprint server for biology. 2023-11-21. PMID:37986868. |
glutamate inputs send prediction error of reward but not negative value of aversive stimuli to dopamine neurons. |
2023-11-21 |
2023-11-29 |
Not clear |
| Ryunosuke Amo, Naoshige Uchida, Mitsuko Watabe-Uchid. Glutamate inputs send prediction error of reward but not negative value of aversive stimuli to dopamine neurons. bioRxiv : the preprint server for biology. 2023-11-21. PMID:37986868. |
we found that glutamate inputs exhibit virtually all of the characteristics of rpe, rather than conveying a specific component of rpe computation such as reward or expectation. |
2023-11-21 |
2023-11-29 |
Not clear |
| Ryunosuke Amo, Naoshige Uchida, Mitsuko Watabe-Uchid. Glutamate inputs send prediction error of reward but not negative value of aversive stimuli to dopamine neurons. bioRxiv : the preprint server for biology. 2023-11-21. PMID:37986868. |
notably, while glutamate inputs were transiently inhibited by reward omission, they were excited by aversive stimuli. |
2023-11-21 |
2023-11-29 |
Not clear |
| b' Giovanni Hernandez, Willemieke M Kouwenhoven, Emmanuelle Poirier, Karim Lebied, Daniel L\\xc3\\xa9vesque, Pierre-Paul Rompr\\xc3\\xa. Dorsal raphe stimulation relays a reward signal to the ventral tegmental area via GluN2C NMDA receptors. PloS one. vol 18. issue 11. 2023-11-06. PMID:37930965.' |
glutamate relays a reward signal from the dorsal raphe (dr) to the ventral tegmental area (vta). |
2023-11-06 |
2023-11-08 |
Not clear |
| Kristen Kim, Marina R Picciott. Nicotine addiction: More than just dopamine. Current opinion in neurobiology. vol 83. 2023-10-13. PMID:37832393. |
in particular, although dopaminergic mechanisms are necessary for nicotine-dependent reward and drug-seeking, novel glutamate and gaba signaling mechanisms in the mesolimbic system have been identified for their contributions to reward-related behaviors. |
2023-10-13 |
2023-10-15 |
Not clear |
| Cristina Ibáñez, Tirso Acuña, María Elena Quintanilla, Diliana Pérez-Reytor, Paola Morales, Eduardo Karahania. Fenofibrate Decreases Ethanol-Induced Neuroinflammation and Oxidative Stress and Reduces Alcohol Relapse in Rats by a PPAR-α-Dependent Mechanism. Antioxidants (Basel, Switzerland). vol 12. issue 9. 2023-09-28. PMID:37760061. |
this inflammation boosts glutamate, prompting dopamine release in reward centers, driving prolonged drinking and relapse. |
2023-09-28 |
2023-10-07 |
rat |
| Lauren Faget, Lucie Oriol, Wen-Chun Lee, Cody Sargent, Dhakshin Ramanathan, Thomas S Hnask. Ventral pallidum GABA and glutamate neurons drive approach and avoidance through distinct modulation of VTA cell types. bioRxiv : the preprint server for biology. 2023-07-28. PMID:37502884. |
here, we found that both vp gaba and glut neurons were activated during approach to reward or delivery of an aversive stimulus. |
2023-07-28 |
2023-08-14 |
human |
| Yiting Hu, Fang Dong, Ting Xue, Mi Zhou, Ruoyan Huang, Feng Sui, Qiang Guo, Wenbao Hou, Wenlong Cai, Kai Yuan, Hongde Wang, Dahua Y. Glutamate levels in the ventromedial prefrontal cortex and resting-state functional connectivity within reward circuits in alcohol-dependent patients. Addiction biology. vol 28. issue 4. 2023-04-05. PMID:37016753. |
glutamate levels in the ventromedial prefrontal cortex and resting-state functional connectivity within reward circuits in alcohol-dependent patients. |
2023-04-05 |
2023-08-14 |
Not clear |
| Yiting Hu, Fang Dong, Ting Xue, Mi Zhou, Ruoyan Huang, Feng Sui, Qiang Guo, Wenbao Hou, Wenlong Cai, Kai Yuan, Hongde Wang, Dahua Y. Glutamate levels in the ventromedial prefrontal cortex and resting-state functional connectivity within reward circuits in alcohol-dependent patients. Addiction biology. vol 28. issue 4. 2023-04-05. PMID:37016753. |
however, little is known about the potential implications of glutamate levels in the prefrontal cortex on abnormal interactions within reward circuits in ad patients. |
2023-04-05 |
2023-08-14 |
Not clear |
| Karen Tangmose, Egill Rostrup, Kirsten B Bojesen, Anne Sigvard, Kasper Jessen, Louise Baruël Johansen, Birte Y Glenthøj, Mette Ødegaard Nielse. Reward disturbances in antipsychotic-naïve patients with first-episode psychosis and their association to glutamate levels. Psychological medicine. vol 53. issue 4. 2023-04-03. PMID:37010221. |
reward disturbances in antipsychotic-naïve patients with first-episode psychosis and their association to glutamate levels. |
2023-04-03 |
2023-08-14 |
Not clear |
| Yuxiao Zhang, Yan Chen, Yushi Xin, Beibei Peng, Shuai Li. Norepinephrine system at the interface of attention and reward. Progress in neuro-psychopharmacology & biological psychiatry. 2023-03-18. PMID:36933778. |
the lc receives reward related sensory, perceptual, and visceral inputs, releases ne, glutamate, dopamine and various neuropeptides, forms reward memories, drives attentional bias and selects behavioral strategies for reward. |
2023-03-18 |
2023-08-14 |
Not clear |
| Peixia Shi, Linlin Hu, Hui Ren, Qin Da. Reward enhances resilience to chronic social defeat stress in mice: Neural ECs and mGluR5 mechanism Frontiers in psychiatry. vol 14. 2023-03-06. PMID:36873216. |
it has been reported that the endogenous cannabinoid system (ecs) and downstream metabolic glutamate receptor 5 (mglur5) are closely related to stress and reward, which might be the potential cerebral mechanism between reward and stress resilience, but there is a lack of direct evidence. |
2023-03-06 |
2023-08-14 |
mouse |
| Laura C Ornelas, Giorgia Boero, Kalynn Van Voorhies, Todd K O'Buckley, Joyce Besheer, A Leslie Morro. Pharmacological administration of 3α,5α-THP into nucleus accumbens core increases 3α,5α-THP expression and reduces alcohol self-administration. Alcoholism, clinical and experimental research. 2023-01-01. PMID:36587947. |
alcohol affects multiple circuits in the brain, mainly disrupting the delicate balance between inhibitory γ-aminobutyric acid (gaba) transmission and excitatory glutamate signaling in brain areas involved in reward circuits, such as amygdala, nucleus accumbens (acb) and ventral tegmental area (vta), causing loss of control in circuits that regulate behavioral control of craving, alcohol-seeking and intake. |
2023-01-01 |
2023-08-14 |
human |
| Li-Min Mao, Nirav Mathur, John Q Wan. An allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors reduces the cocaine-stimulated ERK1/2 phosphorylation in the mouse striatum. Neuroscience letters. 2022-12-24. PMID:36565803. |
metabotropic glutamate (mglu) receptors are involved in the experience-dependent neuroplasticity in the mesolimbic reward circuit. |
2022-12-24 |
2023-08-14 |
mouse |
| Samuel A Barnes, Daniel G Dillon, Jared W Young, Michael L Thomas, Lauren Faget, Ji Hoon Yoo, Andre Der-Avakian, Thomas S Hnasko, Mark A Geyer, Dhakshin S Ramanatha. Modulation of ventromedial orbitofrontal cortical glutamatergic activity affects the explore-exploit balance and influences value-based decision-making. Cerebral cortex (New York, N.Y. : 1991). 2022-12-06. PMID:36472411. |
our findings support the premise that pharmacological interventions that normalize aberrant vmofc glutamate activity during reward feedback processing may attenuate deficits in value-based decision-making. |
2022-12-06 |
2023-08-14 |
rat |
| Daozhong Jin, Hong Chen, Shao-Rui Chen, Hui-Lin Pa. α2δ-1 Protein drives opioid-induced conditioned reward and synaptic NMDA receptor hyperactivity in the nucleus accumbens. Journal of neurochemistry. 2022-10-12. PMID:36222452. |
glutamate nmda receptors (nmdars) in the nucleus accumbens (nac) are critically involved in drug dependence and reward. |
2022-10-12 |
2023-08-14 |
mouse |
| Shuo Li, Xiao-Qin Zhang, Chuan-Chuan Liu, Zhi-Yuan Wang, Guan-Yi Lu, Hao-Wei Shen, Ning Wu, Jin Li, Fei L. IRAS/Nischarin modulates morphine reward by glutamate receptor activation in the nucleus accumbens of mouse brain. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 153. 2022-09-09. PMID:36076473. |
iras/nischarin modulates morphine reward by glutamate receptor activation in the nucleus accumbens of mouse brain. |
2022-09-09 |
2023-08-14 |
mouse |
| Yi He, Graziella Madeo, Ying Liang, Cindy Zhang, Briana Hempel, Xiaojie Liu, Lianwei Mu, Shui Liu, Guo-Hua Bi, Ewa Galaj, Hai-Ying Zhang, Hui Shen, Ross A McDevitt, Eliot L Gardner, Qing-Song Liu, Zheng-Xiong X. A red nucleus-VTA glutamate pathway underlies exercise reward and the therapeutic effect of exercise on cocaine use. Science advances. vol 8. issue 35. 2022-09-02. PMID:36054363. |
a red nucleus-vta glutamate pathway underlies exercise reward and the therapeutic effect of exercise on cocaine use. |
2022-09-02 |
2023-08-14 |
Not clear |
| Cayque Brietzke, Julio Cesar Silva Cesario, Florentina Johanna Hettinga, Flavio Oliveira Pire. The reward for placebos: mechanisms underpinning placebo-induced effects on motor performance. European journal of applied physiology. 2022-08-25. PMID:36006479. |
alterations in the dopamine, opioid, and glutamate metabolism are the neural representation converting reward-derived declarative forms into an attractive and wanted behavior, thereby changing the activation in reward subcortical and cortical structures involved in motor planning, motor execution, and emotional-cognitive attributes of decision-making. |
2022-08-25 |
2023-08-14 |
Not clear |