| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marina S Zacarias, Anna C Ramos, Danielle R Alves, José C F Galduró. Biperiden (an M1 antagonist) reduces memory consolidation of cocaine-conditioned place preference. Neuroscience letters. vol 513. issue 2. 2012-09-18. PMID:22336140. |
although the mesolimbic dopamine (da) system, which originates in the ventral tegmental area (vta) and projects to several forebrain structures, is known to be critically involved in the neurobiology of cocaine dependence, acetylcholine (ach) has also been shown to play an important role in cocaine dependence via its action on this reward system. |
2012-09-18 |
2023-08-12 |
mouse |
| Erik B Oleson, Mark J Ferris, Rodrigo A España, Jill Harp, Sara R Jone. Effects of the histamine H₁ receptor antagonist and benztropine analog diphenylpyraline on dopamine uptake, locomotion and reward. European journal of pharmacology. vol 683. issue 1-3. 2012-09-13. PMID:22445882. |
effects of the histamine h₁ receptor antagonist and benztropine analog diphenylpyraline on dopamine uptake, locomotion and reward. |
2012-09-13 |
2023-08-12 |
Not clear |
| Erik B Oleson, Mark J Ferris, Rodrigo A España, Jill Harp, Sara R Jone. Effects of the histamine H₁ receptor antagonist and benztropine analog diphenylpyraline on dopamine uptake, locomotion and reward. European journal of pharmacology. vol 683. issue 1-3. 2012-09-13. PMID:22445882. |
aside from producing the desired histamine reducing effects, many antihistamines can also elicit psychomotor activation and reward, both of which are associated with increased dopamine concentrations in the nucleus accumbens (nac). |
2012-09-13 |
2023-08-12 |
Not clear |
| Janet K Coller, Mark R Hutchinso. Implications of central immune signaling caused by drugs of abuse: mechanisms, mediators and new therapeutic approaches for prediction and treatment of drug dependence. Pharmacology & therapeutics. vol 134. issue 2. 2012-09-12. PMID:22316499. |
however, more recently this drug-induced activation of central immune signaling is now understood to contribute substantially to the pharmacodynamic actions of the drugs of abuse, by enhancing the engagement of classical mesolimbic dopamine reward pathways and withdrawal centers. |
2012-09-12 |
2023-08-12 |
human |
| Monica Luciana, Dustin Wahlstrom, James N Porter, Paul F Collin. Dopaminergic modulation of incentive motivation in adolescence: age-related changes in signaling, individual differences, and implications for the development of self-regulation. Developmental psychology. vol 48. issue 3. 2012-09-04. PMID:22390660. |
potential mechanisms of variation in functional mesoaccumbens dopamine transmission are discussed with a focus on the interplay between tonic and phasic modes of dopamine transmission in modulating both general incentive-motivational biases and the efficacy of reward learning during exposure to novel reward experiences. |
2012-09-04 |
2023-08-12 |
Not clear |
| Kanji Yoshimoto, Yoshihisa Watanabe, Masaki Tanaka, Minoru Kimur. Serotonin2C receptors in the nucleus accumbens are involved in enhanced alcohol-drinking behavior. The European journal of neuroscience. vol 35. issue 8. 2012-08-27. PMID:22512261. |
dopamine and serotonin (5-ht) in the nucleus accumbens (acc) and ventral tegmental area of the mesoaccumbens reward pathways have been implicated in the mechanisms underlying development of alcohol dependence. |
2012-08-27 |
2023-08-12 |
mouse |
| Simon Thornley, Bruce Russell, Rob Kyd. Carbohydrate reward and psychosis: an explanation for neuroleptic induced weight gain and path to improved mental health? Current neuropharmacology. vol 9. issue 2. 2012-08-23. PMID:22131945. |
evidence links dopamine release in the mid-brain to the pathophysiology of psychosis, addiction and reward. |
2012-08-23 |
2023-08-12 |
Not clear |
| Simon Thornley, Bruce Russell, Rob Kyd. Carbohydrate reward and psychosis: an explanation for neuroleptic induced weight gain and path to improved mental health? Current neuropharmacology. vol 9. issue 2. 2012-08-23. PMID:22131945. |
in this paper, we explore the role of dopamine in reward and psychosis, and discuss how reward pathways may contribute to the weight gain that commonly follows antipsychotic drug use, in people with psychotic illness. |
2012-08-23 |
2023-08-12 |
Not clear |
| Anna C Ramos, Monica L Andersen, Maria G M Oliveira, Aline C Soeiro, José C F Galduró. Biperiden (M₁ antagonist) impairs the expression of cocaine conditioned place preference but potentiates the expression of cocaine-induced behavioral sensitization. Behavioural brain research. vol 231. issue 1. 2012-08-20. PMID:22469627. |
as all drugs of abuse, cocaine acts on the brain reward system, increasing dopamine (da) levels. |
2012-08-20 |
2023-08-12 |
mouse |
| Charlotte A Hardman, Vanessa M B Herbert, Jeffrey M Brunstrom, Marcus R Munafò, Peter J Roger. Dopamine and food reward: effects of acute tyrosine/phenylalanine depletion on appetite. Physiology & behavior. vol 105. issue 5. 2012-08-15. PMID:22230253. |
dopamine and food reward: effects of acute tyrosine/phenylalanine depletion on appetite. |
2012-08-15 |
2023-08-12 |
human |
| Charlotte A Hardman, Vanessa M B Herbert, Jeffrey M Brunstrom, Marcus R Munafò, Peter J Roger. Dopamine and food reward: effects of acute tyrosine/phenylalanine depletion on appetite. Physiology & behavior. vol 105. issue 5. 2012-08-15. PMID:22230253. |
the current study used acute tyrosine/phenylalanine depletion (atpd) to investigate the effect of reduced dopamine function on appetite and the reward value of food in healthy volunteers. |
2012-08-15 |
2023-08-12 |
human |
| Marc Guitart-Masip, Rumana Chowdhury, Tali Sharot, Peter Dayan, Emrah Duzel, Raymond J Dola. Action controls dopaminergic enhancement of reward representations. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 19. 2012-08-13. PMID:22529363. |
here, we manipulated dopamine pharmacologically and examined the effect on a task that explicitly dissociates action and reward value. |
2012-08-13 |
2023-08-12 |
Not clear |
| Marc Guitart-Masip, Rumana Chowdhury, Tali Sharot, Peter Dayan, Emrah Duzel, Raymond J Dola. Action controls dopaminergic enhancement of reward representations. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 19. 2012-08-13. PMID:22529363. |
we show that dopamine enhanced the neural representation of rewarding actions, without significantly affecting the representation of reward value as such. |
2012-08-13 |
2023-08-12 |
Not clear |
| Marc Guitart-Masip, Rumana Chowdhury, Tali Sharot, Peter Dayan, Emrah Duzel, Raymond J Dola. Action controls dopaminergic enhancement of reward representations. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 19. 2012-08-13. PMID:22529363. |
thus, increasing dopamine levels with levodopa selectively boosted striatal and substantia nigra/ventral tegmental representations associated with actions leading to reward, but not with actions leading to the avoidance of punishment. |
2012-08-13 |
2023-08-12 |
Not clear |
| Elizabeth E Van Voorhees, John T Mitchell, F Joseph McClernon, Jean C Beckham, Scott H Kollin. Sex, ADHD symptoms, and smoking outcomes: an integrative model. Medical hypotheses. vol 78. issue 5. 2012-08-09. PMID:22341778. |
on a neurobiological level, the dopamine reward processing system may be implicated in the potentially unique interaction of nicotine with sex and with adhd status. |
2012-08-09 |
2023-08-12 |
Not clear |
| Elizabeth E Van Voorhees, John T Mitchell, F Joseph McClernon, Jean C Beckham, Scott H Kollin. Sex, ADHD symptoms, and smoking outcomes: an integrative model. Medical hypotheses. vol 78. issue 5. 2012-08-09. PMID:22341778. |
specifically, nicotine appears to mitigate core adhd symptoms through interaction with the dopamine reward processing system, and ovarian hormones have been found to interact with nicotine within the dopamine reward processing system to affect neurotransmitter release and functioning. |
2012-08-09 |
2023-08-12 |
Not clear |
| Elizabeth E Van Voorhees, John T Mitchell, F Joseph McClernon, Jean C Beckham, Scott H Kollin. Sex, ADHD symptoms, and smoking outcomes: an integrative model. Medical hypotheses. vol 78. issue 5. 2012-08-09. PMID:22341778. |
based upon this model, the following hypotheses are proposed at the intersection of each of the three variables of sex, adhd, and smoking: (1) individuals with adhd have altered functioning of the dopamine reward system, which diminishes their ability to efficiently form conditioned associations based on environmental contingencies; these deficits are partially ameliorated by nicotine; (2) nicotine interacts with estrogen and the dopamine reward system to increase the positive and negative reinforcement value of smoking in female smokers; (3) in adult females with adhd, ovarian hormones interact with the dopamine reward system to exacerbate adhd-related deficits in the capacity to form conditioned associations; and (4) during different phases of the menstrual cycle, nicotine and ovarian hormones may interact differentially with the dopamine reward processing system to affect the type and value of reinforcement smoking provides for women with adhd. |
2012-08-09 |
2023-08-12 |
Not clear |
| Elizabeth E Van Voorhees, John T Mitchell, F Joseph McClernon, Jean C Beckham, Scott H Kollin. Sex, ADHD symptoms, and smoking outcomes: an integrative model. Medical hypotheses. vol 78. issue 5. 2012-08-09. PMID:22341778. |
overall, the goal of this paper is to examine the interaction of sex, smoking, and adhd status within the context of the dopamine reward processing system not only to elucidate potential mechanisms specific to female smokers with adhd, but also to stimulate consideration of how the examination of such individual differences can inform our understanding of smoking more broadly. |
2012-08-09 |
2023-08-12 |
Not clear |
| Julia P Dunn, Robert M Kessler, Irene D Feurer, Nora D Volkow, Bruce W Patterson, Mohammad S Ansari, Rui Li, Pamela Marks-Shulman, Naji N Abumra. Relationship of dopamine type 2 receptor binding potential with fasting neuroendocrine hormones and insulin sensitivity in human obesity. Diabetes care. vol 35. issue 5. 2012-08-09. PMID:22432117. |
midbrain dopamine (da) neurons, which are involved with reward and motivation, are modulated by hormones that regulate food intake (insulin, leptin, and acyl ghrelin [ag]). |
2012-08-09 |
2023-08-12 |
human |
| Katherine H Taber, Deborah N Black, Linda J Porrino, Robin A Hurle. Neuroanatomy of dopamine: reward and addiction. The Journal of neuropsychiatry and clinical neurosciences. vol 24. issue 1. 2012-08-08. PMID:22450608. |
neuroanatomy of dopamine: reward and addiction. |
2012-08-08 |
2023-08-12 |
Not clear |