| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eric Stice, Sonja Yokum, Kyle Burger, Leonard Epstein, Andy Smole. Multilocus genetic composite reflecting dopamine signaling capacity predicts reward circuitry responsivity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 29. 2012-10-24. PMID:22815523. |
multilocus genetic composite reflecting dopamine signaling capacity predicts reward circuitry responsivity. |
2012-10-24 |
2023-08-12 |
human |
| Eric Stice, Sonja Yokum, Kyle Burger, Leonard Epstein, Andy Smole. Multilocus genetic composite reflecting dopamine signaling capacity predicts reward circuitry responsivity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 29. 2012-10-24. PMID:22815523. |
the objective of the study was to test the hypotheses that humans with genotypes putatively associated with low dopamine (da) signaling capacity, including the taqia a1 allele, drd2-141c ins/ins genotype, drd4 7-repeat or longer allele, dat1 10-repeat allele, and the met/met comt genotype, and with a greater number of these genotypes per a multilocus composite, show less responsivity of reward regions that primarily rely on da signaling. |
2012-10-24 |
2023-08-12 |
human |
| Amine Bahi, Jean-Luc Dreye. Involvement of nucleus accumbens dopamine D1 receptors in ethanol drinking, ethanol-induced conditioned place preference, and ethanol-induced psychomotor sensitization in mice. Psychopharmacology. vol 222. issue 1. 2012-10-22. PMID:22222864. |
dopamine d1 receptor (d1r) signaling has been associated to ethanol consumption and reward in laboratory animals. |
2012-10-22 |
2023-08-12 |
mouse |
| Masamichi Sakagami, Manami Yamamot. [Value representation in the striatum and prefrontal cortex]. Brain and nerve = Shinkei kenkyu no shinpo. vol 64. issue 8. 2012-10-18. PMID:22868880. |
to clarify the neuronal correlates of the multiple processes on reward prediction, we have conducted 4 experiments: (1) single-unit recording from the caudate and lateral prefrontal cortex of a monkey, while it performed a memory-guided saccade task with asymmetric reward schedule; (2) human fmri imaging during random-dot discrimination with asymmetric reward condition; (3) single-unit recording from the monkey dopamine neuron in the random-dot discrimination task with asymmetric reward schedule; and (4) simultaneous single-unit recording from the striatum and lateral prefrontal cortex of monkeys performing a reward inference task. |
2012-10-18 |
2023-08-12 |
human |
| Kyung Man Kim, Michael V Baratta, Aimei Yang, Doheon Lee, Edward S Boyden, Christopher D Fiorill. Optogenetic mimicry of the transient activation of dopamine neurons by natural reward is sufficient for operant reinforcement. PloS one. vol 7. issue 4. 2012-10-17. PMID:22506004. |
optogenetic mimicry of the transient activation of dopamine neurons by natural reward is sufficient for operant reinforcement. |
2012-10-17 |
2023-08-12 |
mouse |
| Kyung Man Kim, Michael V Baratta, Aimei Yang, Doheon Lee, Edward S Boyden, Christopher D Fiorill. Optogenetic mimicry of the transient activation of dopamine neurons by natural reward is sufficient for operant reinforcement. PloS one. vol 7. issue 4. 2012-10-17. PMID:22506004. |
however, the firing rate of dopamine neurons is increased for only about 200 milliseconds following natural reward events that are better than expected, a response which has been described as a "reward prediction error" (rpe). |
2012-10-17 |
2023-08-12 |
mouse |
| Kyung Man Kim, Michael V Baratta, Aimei Yang, Doheon Lee, Edward S Boyden, Christopher D Fiorill. Optogenetic mimicry of the transient activation of dopamine neurons by natural reward is sufficient for operant reinforcement. PloS one. vol 7. issue 4. 2012-10-17. PMID:22506004. |
we mimicked the transient activation of dopamine neurons that occurs in response to natural reward by applying a light pulse of 200 ms in vta. |
2012-10-17 |
2023-08-12 |
mouse |
| Kyung Man Kim, Michael V Baratta, Aimei Yang, Doheon Lee, Edward S Boyden, Christopher D Fiorill. Optogenetic mimicry of the transient activation of dopamine neurons by natural reward is sufficient for operant reinforcement. PloS one. vol 7. issue 4. 2012-10-17. PMID:22506004. |
these results provide strong evidence that the transient activation of dopamine neurons provides a functional reward signal that drives learning, in support of rl theories of dopamine function. |
2012-10-17 |
2023-08-12 |
mouse |
| M C Velásquez-Martinez, R Vázquez-Torres, C A Jiménez-River. Activation of alpha1-adrenoceptors enhances glutamate release onto ventral tegmental area dopamine cells. Neuroscience. vol 216. 2012-10-17. PMID:22542873. |
glutamatergic inputs into the vta contribute to dopamine (da) neuronal activation related to reward and response-initiating effects in drug abuse. |
2012-10-17 |
2023-08-12 |
rat |
| James E McCutcheon, Stephanie R Ebner, Amy L Loriaux, Mitchell F Roitma. Encoding of aversion by dopamine and the nucleus accumbens. Frontiers in neuroscience. vol 6. 2012-10-12. PMID:23055953. |
classically, the nucleus accumbens (nac) and the dopamine projection to it are considered an integral part of the brain's reward circuit, i.e., they direct approach and consumption behaviors and underlie positive reinforcement. |
2012-10-12 |
2023-08-12 |
rat |
| James E McCutcheon, Stephanie R Ebner, Amy L Loriaux, Mitchell F Roitma. Encoding of aversion by dopamine and the nucleus accumbens. Frontiers in neuroscience. vol 6. 2012-10-12. PMID:23055953. |
together with our data, the emerging literature suggests an important role for differential phasic dopamine signaling in aversion vs. reward. |
2012-10-12 |
2023-08-12 |
rat |
| Wonho Lee, Riju Ray, Andrew W Bergen, Gary E Swan, Paul Thomas, Rachel F Tyndale, Neal L Benowitz, Caryn Lerman, David V Cont. DRD1 associations with smoking abstinence across slow and normal nicotine metabolizers. Pharmacogenetics and genomics. vol 22. issue 7. 2012-10-11. PMID:22495174. |
in two randomized clinical trials of smoking abstinence treatments, we conducted nmr-stratified analyses on smoking abstinence across 13 regions coding for nicotinic acetylcholine receptors and proteins involved in the dopamine reward system. |
2012-10-11 |
2023-08-12 |
Not clear |
| Ja Wook Koo, Michelle S Mazei-Robison, Dipesh Chaudhury, Barbara Juarez, Quincey LaPlant, Deveroux Ferguson, Jian Feng, Haosheng Sun, Kimberly N Scobie, Diane Damez-Werno, Marshall Crumiller, Yoshinori N Ohnishi, Yoko H Ohnishi, Ezekiell Mouzon, David M Dietz, Mary Kay Lobo, Rachael L Neve, Scott J Russo, Ming-Hu Han, Eric J Nestle. BDNF is a negative modulator of morphine action. Science (New York, N.Y.). vol 338. issue 6103. 2012-10-11. PMID:23042896. |
the suppression of bdnf in the ventral tegmental area (vta) enhanced the ability of morphine to increase dopamine (da) neuron excitability and promote reward. |
2012-10-11 |
2023-08-12 |
Not clear |
| Anton Ilango, Jason Shumake, Wolfram Wetzel, Henning Scheich, Frank W Oh. The role of dopamine in the context of aversive stimuli with particular reference to acoustically signaled avoidance learning. Frontiers in neuroscience. vol 6. 2012-10-11. PMID:23049495. |
several studies have explored the contribution of released dopamine (da) or responses of da neurons on reward seeking using rewards such as food, water, and sex. |
2012-10-11 |
2023-08-12 |
Not clear |
| Susanne Becker, Wiebke Gandhi, Petra Schweinhard. Cerebral interactions of pain and reward and their relevance for chronic pain. Neuroscience letters. vol 520. issue 2. 2012-10-05. PMID:22440855. |
cerebral processing of hedonic ('liking') and motivational ('wanting') aspects of reward can be separated: the orbitofrontal cortex and opioids play an important role for the hedonic experience, and the ventral striatum and dopamine predominantly process motivation for reward. |
2012-10-05 |
2023-08-12 |
Not clear |
| Elly Sinkala, James E McCutcheon, Matthew J Schuck, Eric Schmidt, Mitchell F Roitman, David T Eddingto. Electrode calibration with a microfluidic flow cell for fast-scan cyclic voltammetry. Lab on a chip. vol 12. issue 13. 2012-10-03. PMID:22522908. |
to demonstrate this, an electrode calibrated with the μfc was used in fscv recordings from a rat during the delivery of food reward--a stimulus that reliably evokes a brief increase in current due to the oxidation of dopamine. |
2012-10-03 |
2023-08-12 |
rat |
| Regan G Wisnewski, Johan Lauwereyn. Systemic dizocilpine (MK-801) facilitates performance in opposition to response bias. Behavioral and brain functions : BBF. vol 3. 2012-10-02. PMID:17880723. |
previous research has established that dopamine signals are crucial in orienting behavior to reward. |
2012-10-02 |
2023-08-12 |
rat |
| B de Brettes, I Berlin, C Laurent, J Lépine, J Mallet, A Puec. The dopamine D2 receptor gene TaqI A polymorphism is not associated with Novelty Seeking, Harm Avoidance and Reward Dependence in healthy subjects. European psychiatry : the journal of the Association of European Psychiatrists. vol 13. issue 8. 2012-10-02. PMID:19698661. |
the dopamine d2 receptor gene taqi a polymorphism is not associated with novelty seeking, harm avoidance and reward dependence in healthy subjects. |
2012-10-02 |
2023-08-12 |
human |
| R J Beninge. D-1 receptor involvement in reward-related learning. Journal of psychopharmacology (Oxford, England). vol 6. issue 1. 2012-10-02. PMID:22291240. |
a comparison of the effects of apomorphine, amphetamine and dopamine (da) receptor subtype-specific agonists in responding for conditioned reward, self-administration and place conditioning paradigms provides insights into the possible involvement of d-1 and d-2 receptors in reward-related learning. |
2012-10-02 |
2023-08-12 |
Not clear |
| Katsuhiko Shibuya, Yoshihito Funaki, Kotaro Hiraoka, Takeo Yoshikawa, Fumito Naganuma, Masayasu Miyake, Shoichi Watanuki, Hirotoshi Sato, Manabu Tashiro, Kazuhiko Yana. [(11)C]Doxepin binding to histamine H1 receptors in living human brain: reproducibility during attentive waking and circadian rhythm. Frontiers in systems neuroscience. vol 6. 2012-10-02. PMID:22701403. |
previous studies using [(11)c]raclopride and [(11)c]flb457 revealed that the release of neuronal dopamine was increased in human brain by psychostimulants or reward stimuli. |
2012-10-02 |
2023-08-12 |
human |