| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David Stacey, Ainhoa Bilbao, Matthieu Maroteaux, Tianye Jia, Alanna C Easton, Sophie Longueville, Charlotte Nymberg, Tobias Banaschewski, Gareth J Barker, Christian Büchel, Fabiana Carvalho, Patricia J Conrod, Sylvane Desrivières, Mira Fauth-Bühler, Alberto Fernandez-Medarde, Herta Flor, Jürgen Gallinat, Hugh Garavan, Arun L W Bokde, Andreas Heinz, Bernd Ittermann, Mark Lathrop, Claire Lawrence, Eva Loth, Anbarasu Lourdusamy, Karl F Mann, Jean-Luc Martinot, Frauke Nees, Miklós Palkovits, Tomas Paus, Zdenka Pausova, Marcella Rietschel, Barbara Ruggeri, Eugenio Santos, Michael N Smolka, Oliver Staehlin, Marjo-Riitta Jarvelin, Paul Elliott, Wolfgang H Sommer, Manuel Mameli, Christian P Müller, Rainer Spanagel, Jean-Antoine Girault, Gunter Schuman. RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 51. 2013-02-28. PMID:23223532. |
together, these combined animal and human data indicate a role for rasgrf2 in the regulation of mesolimbic dopamine neuron activity, reward response, and alcohol use and abuse. |
2013-02-28 |
2023-08-12 |
mouse |
| Ryan M Drenan, Henry A Leste. Insights into the neurobiology of the nicotinic cholinergic system and nicotine addiction from mice expressing nicotinic receptors harboring gain-of-function mutations. Pharmacological reviews. vol 64. issue 4. 2013-02-21. PMID:22885704. |
these α4 nachr gain-of-function mice (α4 l9's mice, followed by α4 l9'a mice) provided an important system to probe α4 nachr function in vivo, particularly in the dopamine reward system. |
2013-02-21 |
2023-08-12 |
mouse |
| Xiang Yang Zhang, Da Chun Chen, Mei Hong Xiu, Li Hui, Haibo Liu, Xingguang Luo, Lingjun Zuo, Huiping Zhang, Therese A Kosten, Thomas R Koste. Association of functional dopamine-beta-hydroxylase (DBH) 19 bp insertion/deletion polymorphism with smoking severity in male schizophrenic smokers. Schizophrenia research. vol 141. issue 1. 2013-02-13. PMID:22871345. |
the mechanism for such an association may reflect nicotine's mediation of drug reward in the brain through actions on dopamine, a key mediator of drug reward. |
2013-02-13 |
2023-08-12 |
Not clear |
| Mette Odegaard Nielsen, Egill Rostrup, Sanne Wulff, Nikolaj Bak, Brian Villumsen Broberg, Henrik Lublin, Shitij Kapur, Birte Glentho. Improvement of brain reward abnormalities by antipsychotic monotherapy in schizophrenia. Archives of general psychiatry. vol 69. issue 12. 2013-02-12. PMID:22868877. |
context schizophrenic symptoms are linked to a dysfunction of dopamine neurotransmission and the brain reward system. |
2013-02-12 |
2023-08-12 |
human |
| Christopher J Burke, Wolf Huetteroth, David Owald, Emmanuel Perisse, Michael J Krashes, Gaurav Das, Daryl Gohl, Marion Silies, Sarah Certel, Scott Waddel. Layered reward signalling through octopamine and dopamine in Drosophila. Nature. vol 492. issue 7429. 2013-02-12. PMID:23103875. |
layered reward signalling through octopamine and dopamine in drosophila. |
2013-02-12 |
2023-08-12 |
drosophila_melanogaster |
| Christopher J Burke, Wolf Huetteroth, David Owald, Emmanuel Perisse, Michael J Krashes, Gaurav Das, Daryl Gohl, Marion Silies, Sarah Certel, Scott Waddel. Layered reward signalling through octopamine and dopamine in Drosophila. Nature. vol 492. issue 7429. 2013-02-12. PMID:23103875. |
dopamine is synonymous with reward and motivation in mammals. |
2013-02-12 |
2023-08-12 |
drosophila_melanogaster |
| Jeffrey L Krichma. A neurorobotic platform to test the influence of neuromodulatory signaling on anxious and curious behavior. Frontiers in neurorobotics. vol 7. 2013-02-07. PMID:23386829. |
whereas changes in the overall level of dopamine (da) have an effect on the organism's reward or curiosity-seeking behavior, changes in the level of serotonin (5-ht) can affect its level of anxiety or harm aversion. |
2013-02-07 |
2023-08-12 |
Not clear |
| P Smittenaar, H W Chase, E Aarts, B Nusselein, B R Bloem, R Cool. Decomposing effects of dopaminergic medication in Parkinson's disease on probabilistic action selection--learning or performance? The European journal of neuroscience. vol 35. issue 7. 2013-02-05. PMID:22487043. |
these data demonstrate that the effects of dopamine on probabilistic action selection are at least partly mediated by effects on the expression of learned associations rather than on learning itself, and help refine current models of dopamine's role in reward. |
2013-02-05 |
2023-08-12 |
Not clear |
| N D Volkow, G-J Wang, D Tomasi, R D Bale. Obesity and addiction: neurobiological overlaps. Obesity reviews : an official journal of the International Association for the Study of Obesity. vol 14. issue 1. 2013-02-01. PMID:23016694. |
both drugs and food have powerful reinforcing effects, which are in part mediated by abrupt dopamine increases in the brain reward centres. |
2013-02-01 |
2023-08-12 |
Not clear |
| Caroline Davis, Robert D Levitan, Zeynep Yilmaz, Allan S Kaplan, Jacqueline C Carter, James L Kenned. Binge eating disorder and the dopamine D2 receptor: genotypes and sub-phenotypes. Progress in neuro-psychopharmacology & biological psychiatry. vol 38. issue 2. 2013-01-21. PMID:22579533. |
previous research suggests that bed may be an overeating syndrome characterized by a hyper-responsiveness to reward, and a strong dopamine signaling in the neuro-circuitry that regulates pleasure and appetitive behaviors. |
2013-01-21 |
2023-08-12 |
Not clear |
| Elyssa B Margolis, Brian Toy, Patricia Himmels, Marisela Morales, Howard L Field. Identification of rat ventral tegmental area GABAergic neurons. PloS one. vol 7. issue 7. 2013-01-14. PMID:22860119. |
the canonical two neuron model of opioid reward posits that mu opioid receptor (mor) activation produces reward by disinhibiting midbrain ventral tegmental area (vta) dopamine neurons through inhibition of local gabaergic interneurons. |
2013-01-14 |
2023-08-12 |
rat |
| John D Salamone, Mercè Corre. The mysterious motivational functions of mesolimbic dopamine. Neuron. vol 76. issue 3. 2013-01-11. PMID:23141060. |
although it has become traditional to label dopamine neurons as "reward" neurons, this is an overgeneralization, and it is important to distinguish between aspects of motivation that are differentially affected by dopaminergic manipulations. |
2013-01-11 |
2023-08-12 |
Not clear |
| Stephan Lammel, Byung Kook Lim, Chen Ran, Kee Wui Huang, Michael J Betley, Kay M Tye, Karl Deisseroth, Robert C Malenk. Input-specific control of reward and aversion in the ventral tegmental area. Nature. vol 491. issue 7423. 2013-01-10. PMID:23064228. |
ventral tegmental area (vta) dopamine neurons have important roles in adaptive and pathological brain functions related to reward and motivation. |
2013-01-10 |
2023-08-12 |
mouse |
| Rui Song, Hai-Ying Zhang, Xia Li, Guo-Hua Bi, Eliot L Gardner, Zheng-Xiong X. Increased vulnerability to cocaine in mice lacking dopamine D3 receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 43. 2013-01-07. PMID:23045656. |
this increased vulnerability to cocaine is accompanied by decreased dopamine response to cocaine secondary to increased basal levels of extracellular dopamine in the nucleus accumbens, suggesting a compensatory response to decreased cocaine reward in d(3)(-/-) mice. |
2013-01-07 |
2023-08-12 |
mouse |
| Erik B Oleson, Ronny N Gentry, Vivian C Chioma, Joseph F Chee. Subsecond dopamine release in the nucleus accumbens predicts conditioned punishment and its successful avoidance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 42. 2013-01-02. PMID:23077064. |
we also observed subsecond dopamine release during the safety period, as occurs following the receipt of reward. |
2013-01-02 |
2023-08-12 |
rat |
| Gabriel C Loewinger, Michael V Beckert, Hugo A Tejeda, Joseph F Chee. Methamphetamine-induced dopamine terminal deficits in the nucleus accumbens are exacerbated by reward-associated cues and attenuated by CB1 receptor antagonism. Neuropharmacology. vol 62. issue 7. 2012-12-20. PMID:22306525. |
furthermore, we hypothesized that administration of meth in environments where reward associated-cues were present would potentiate meth's acute effects on dopamine release in the nucleus accumbens and exacerbate changes in dopamine terminal activity. |
2012-12-20 |
2023-08-12 |
Not clear |
| Jeff A Beeler, James E McCutcheon, Zhen F H Cao, Mari Murakami, Erin Alexander, Mitchell F Roitman, Xiaoxi Zhuan. Taste uncoupled from nutrition fails to sustain the reinforcing properties of food. The European journal of neuroscience. vol 36. issue 4. 2012-12-20. PMID:22712685. |
in agreement with behavioral data, saccharin-evoked (but not sucrose-evoked) dopamine release is greatly attenuated following pre-exposure, suggesting that nutritional value is critical for dopamine-mediated reward and reinforcement. |
2012-12-20 |
2023-08-12 |
Not clear |
| Benjamin T Saunders, Terry E Robinso. The role of dopamine in the accumbens core in the expression of Pavlovian-conditioned responses. The European journal of neuroscience. vol 36. issue 4. 2012-12-20. PMID:22780554. |
the role of dopamine in reward is a topic of debate. |
2012-12-20 |
2023-08-12 |
Not clear |
| Benjamin T Saunders, Terry E Robinso. The role of dopamine in the accumbens core in the expression of Pavlovian-conditioned responses. The European journal of neuroscience. vol 36. issue 4. 2012-12-20. PMID:22780554. |
for example, some have argued that phasic dopamine signaling provides a prediction-error signal necessary for stimulus-reward learning, whereas others have hypothesized that dopamine is not necessary for learning per se, but for attributing incentive motivational value ('incentive salience') to reward cues. |
2012-12-20 |
2023-08-12 |
Not clear |
| Benjamin T Saunders, Terry E Robinso. The role of dopamine in the accumbens core in the expression of Pavlovian-conditioned responses. The European journal of neuroscience. vol 36. issue 4. 2012-12-20. PMID:22780554. |
to disentangle them we took advantage of natural individual variation in the extent to which reward cues are attributed with incentive salience, and asked whether dopamine (specifically in the core of the nucleus accumbens) is necessary for the expression of two forms of pavlovian-conditioned approach behavior--one in which the cue acquires powerful motivational properties (sign-tracking) and another closely related one in which it does not (goal-tracking). |
2012-12-20 |
2023-08-12 |
Not clear |