| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rhona B C Clarke, Bo Söderpalm, Amir Lotfi, Mia Ericson, Louise Adermar. Involvement of Inhibitory Receptors in Modulating Dopamine Signaling and Synaptic Activity Following Acute Ethanol Exposure in Striatal Subregions. Alcoholism, clinical and experimental research. vol 39. issue 12. 2016-10-06. PMID:26614538. |
alcohol acts on both inhibitory and excitatory receptor systems resulting in a net increase in dopamine output in the ventral striatum (nucleus accumbens [nac]), which is implicated in drug reward. |
2016-10-06 |
2023-08-13 |
Not clear |
| Jörgen A Engel, Ingrid Nylander, Elisabet Jerlha. A ghrelin receptor (GHS-R1A) antagonist attenuates the rewarding properties of morphine and increases opioid peptide levels in reward areas in mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 12. 2016-10-05. PMID:26508707. |
in addition, recent work has pin-pointed that this peptide has a novel role in drug-induced reward, including morphine-induced increase in the extracellular levels of accumbal dopamine in rats. |
2016-10-05 |
2023-08-13 |
mouse |
| Jennifer N Berry, Meredith A Saunders, Lynda J Sharrett-Field, Anna R Reynolds, Michael T Bardo, James R Pauly, Mark A Prendergas. Corticosterone enhances N-methyl-D-aspartate receptor signaling to promote isolated ventral tegmental area activity in a reconstituted mesolimbic dopamine pathway. Brain research bulletin. vol 120. 2016-09-30. PMID:26631585. |
elevations in circulating corticosteroids during periods of stress may influence activity of the mesolimbic dopamine reward pathway by increasing glutamatergic n-methyl-d-aspartate (nmda) receptor expression and/or function in a glucocorticoid receptor-dependent manner. |
2016-09-30 |
2023-08-13 |
Not clear |
| Kei Mizuno, Shinichiro Takiguchi, Mika Yamazaki, Mizuki Asano, Shiho Kato, Kikuko Kuriyama, Yasuyoshi Watanabe, Norihiro Sadato, Akemi Tomod. Impaired neural reward processing in children and adolescents with reactive attachment disorder: A pilot study. Asian journal of psychiatry. vol 17. 2016-09-28. PMID:26310381. |
one of the core characteristics of adhd is a decrease in neural reward processing due to dopamine dysfunction. |
2016-09-28 |
2023-08-13 |
Not clear |
| William C Buchta, Arthur C Riege. Chronic cocaine disrupts mesocortical learning mechanisms. Brain research. vol 1628. issue Pt A. 2016-09-27. PMID:25704202. |
the addictive power of drugs of abuse such as cocaine comes from their ability to hijack natural reward and plasticity mechanisms mediated by dopamine signaling in the brain. |
2016-09-27 |
2023-08-13 |
human |
| William C Buchta, Arthur C Riege. Chronic cocaine disrupts mesocortical learning mechanisms. Brain research. vol 1628. issue Pt A. 2016-09-27. PMID:25704202. |
reward learning involves burst firing of midbrain dopamine neurons in response to rewards and cues predictive of reward. |
2016-09-27 |
2023-08-13 |
human |
| G van der Plasse, R van Zessen, M C M Luijendijk, H Erkan, G D Stuber, G M J Ramakers, R A H Ada. Modulation of cue-induced firing of ventral tegmental area dopamine neurons by leptin and ghrelin. International journal of obesity (2005). vol 39. issue 12. 2016-09-27. PMID:26183405. |
this mesolimbic dopamine (da) system is sensitive to changes in energy balance, yet it has thus far not been established whether reward signaling of da neurons in vivo is under control of hormones that signal appetite and energy balance such as ghrelin and leptin. |
2016-09-27 |
2023-08-13 |
human |
| Kaley MacFadyen, Rebecca Loveless, Brandon DeLucca, Krystal Wardley, Sumeet Deogan, Cameron Thomas, Joanna Peri. Peripheral oxytocin administration reduces ethanol consumption in rats. Pharmacology, biochemistry, and behavior. vol 140. 2016-09-26. PMID:26519603. |
the neuropeptide oxytocin interacts with mesolimbic dopamine neurons to mediate reward associated with filial behaviors, but also other rewarding behaviors such as eating or taking drugs of abuse. |
2016-09-26 |
2023-08-13 |
rat |
| M-P Cossette, K Conover, P Shizga. The neural substrates for the rewarding and dopamine-releasing effects of medial forebrain bundle stimulation have partially discrepant frequency responses. Behavioural brain research. vol 297. 2016-09-20. PMID:26477378. |
this study assessed the hypothesis that midbrain dopamine neurons are in series with the directly stimulated substrate for self-stimulation of the mfb and either perform spatio-temporal integration of synaptic input from directly activated mfb fibers or relay the results of such integration to efferent stages of the reward circuitry. |
2016-09-20 |
2023-08-13 |
human |
| Laura E O'Dell, Arbi Nazaria. Enhanced vulnerability to tobacco use in persons with diabetes: A behavioral and neurobiological framework. Progress in neuro-psychopharmacology & biological psychiatry. vol 65. 2016-09-14. PMID:26092247. |
this framework suggests that diabetes induces a disruption in insulin signaling that leads to a suppression of dopamine systems in the mesolimbic reward pathway. |
2016-09-14 |
2023-08-13 |
Not clear |
| Claudia Sagheddu, Anna Lisa Muntoni, Marco Pistis, Miriam Meli. Endocannabinoid Signaling in Motivation, Reward, and Addiction: Influences on Mesocorticolimbic Dopamine Function. International review of neurobiology. vol 125. 2016-09-14. PMID:26638769. |
endocannabinoid signaling in motivation, reward, and addiction: influences on mesocorticolimbic dopamine function. |
2016-09-14 |
2023-08-13 |
Not clear |
| Claudia Sagheddu, Anna Lisa Muntoni, Marco Pistis, Miriam Meli. Endocannabinoid Signaling in Motivation, Reward, and Addiction: Influences on Mesocorticolimbic Dopamine Function. International review of neurobiology. vol 125. 2016-09-14. PMID:26638769. |
the goal of this chapter is to examine the endocannabinoid influence on dopamine signaling specifically related to (i) those behavioral processes that allow us to successfully adapt to ever-changing environments (i.e., reward signaling and motivational processes) and (ii) derangements from behavioral flexibility that underpin drug addiction. |
2016-09-14 |
2023-08-13 |
Not clear |
| Hiroko Awata, Takahito Watanabe, Yoshitaka Hamanaka, Taro Mito, Sumihare Noji, Makoto Mizunam. Knockout crickets for the study of learning and memory: Dopamine receptor Dop1 mediates aversive but not appetitive reinforcement in crickets. Scientific reports. vol 5. 2016-09-13. PMID:26521965. |
our pharmacological studies suggested that octopamine and dopamine neurons mediate reward and punishment, respectively, in crickets, but recent studies in fruit-flies concluded that dopamine neurons mediates both reward and punishment, via the type 1 dopamine receptor dop1. |
2016-09-13 |
2023-08-13 |
human |
| b' Giovanni Hernandez, Marie-Pierre Cossette, Peter Shizgal, Pierre-Paul Rompr\\xc3\\xa. Ventral Midbrain NMDA Receptor Blockade: From Enhanced Reward and Dopamine Inactivation. Frontiers in behavioral neuroscience. vol 10. 2016-09-12. PMID:27616984.' |
ventral midbrain nmda receptor blockade: from enhanced reward and dopamine inactivation. |
2016-09-12 |
2023-08-13 |
rat |
| b' Giovanni Hernandez, Marie-Pierre Cossette, Peter Shizgal, Pierre-Paul Rompr\\xc3\\xa. Ventral Midbrain NMDA Receptor Blockade: From Enhanced Reward and Dopamine Inactivation. Frontiers in behavioral neuroscience. vol 10. 2016-09-12. PMID:27616984.' |
glutamate stimulates ventral midbrain (vm) n-methyl-d-aspartate receptors (nmdar) to initiate dopamine (da) burst firing activity, a mode of discharge associated with enhanced da release and reward. |
2016-09-12 |
2023-08-13 |
rat |
| Collin B Merrill, Lindsey N Friend, Scott T Newton, Zachary H Hopkins, Jeffrey G Edward. Ventral tegmental area dopamine and GABA neurons: Physiological properties and expression of mRNA for endocannabinoid biosynthetic elements. Scientific reports. vol 5. 2016-09-07. PMID:26553597. |
the ventral tegmental area (vta) is involved in adaptive reward and motivation processing and is composed of dopamine (da) and gaba neurons. |
2016-09-07 |
2023-08-13 |
mouse |
| Hadas Nahman-Averbuch, David Yarnitsky, Elliot Sprecher, Yelena Granovsky, Michal Grano. Relationship between Personality Traits and Endogenous Analgesia: The Role of Harm Avoidance. Pain practice : the official journal of World Institute of Pain. vol 16. issue 1. 2016-09-06. PMID:25353647. |
the neurotransmitters serotonin, dopamine, and norepinephrine are involved both in cpm, as well as personality traits such as harm avoidance (ha), novelty seeking (ns), and reward dependence (rd), which can be obtained by the tridimensional personality questionnaire (tpq). |
2016-09-06 |
2023-08-13 |
Not clear |
| James Edgar McCutcheo. The role of dopamine in the pursuit of nutritional value. Physiology & behavior. vol 152. issue Pt B. 2016-09-06. PMID:25957911. |
the physiological mechanisms underlying these effects are complex but are believed to converge on mesolimbic dopamine signalling to translate post-ingestive sensing of nutrients into reward and reinforcement value. |
2016-09-06 |
2023-08-13 |
human |
| Diana M Tacelosky, Danielle N Alexander, Megan Morse, Andras Hajnal, Arthur Berg, Robert Levenson, Patricia S Grigso. Low expression of D2R and Wntless correlates with high motivation for heroin. Behavioral neuroscience. vol 129. issue 6. 2016-09-01. PMID:26501177. |
the neurotransmitter dopamine also contributes to opioid reward, and opioid addiction has been linked to reduced expression of dopamine d2 receptors (d2r) in the brain. |
2016-09-01 |
2023-08-13 |
Not clear |
| Kenneth Blum, Marcelo Febo, Panayotis K Thanos, David Baron, James Fratantonio, Mark Gol. Clinically Combating Reward Deficiency Syndrome (RDS) with Dopamine Agonist Therapy as a Paradigm Shift: Dopamine for Dinner? Molecular neurobiology. vol 52. issue 3. 2016-08-30. PMID:25750061. |
clinically combating reward deficiency syndrome (rds) with dopamine agonist therapy as a paradigm shift: dopamine for dinner? |
2016-08-30 |
2023-08-13 |
Not clear |