| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Louise M Paterson, Remy S A Flechais, Anna Murphy, Laurence J Reed, Sanja Abbott, Venkataramana Boyapati, Rebecca Elliott, David Erritzoe, Karen D Ersche, Yetunde Faluyi, Luca Faravelli, Emilio Fernandez-Egea, Nicola J Kalk, Shankar S Kuchibatla, John McGonigle, Antonio Metastasio, Inge Mick, Liam Nestor, Csaba Orban, Filippo Passetti, Eugenii A Rabiner, Dana G Smith, John Suckling, Roger Tait, Eleanor M Taylor, Adam D Waldman, Trevor W Robbins, J F William Deakin, David J Nutt, Anne R Lingford-Hughe. The Imperial College Cambridge Manchester (ICCAM) platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part A: Study description. Journal of psychopharmacology (Oxford, England). vol 29. issue 9. 2016-06-22. PMID:26246443. |
pharmacological modulation of reward, impulsivity and emotional reactivity were investigated in a monetary incentive delay task, an inhibitory control task, and an evocative images task, using selective antagonists for µ-opioid, dopamine d3 receptor (drd3) and neurokinin 1 (nk1) receptors (naltrexone, gsk598809, vofopitant/aprepitant), in a placebo-controlled, randomised, crossover design. |
2016-06-22 |
2023-08-13 |
Not clear |
| Behrooz Khakpour-Taleghani, Zahra Reisi, Abbas Haghparas. The Blockade of D1/D2-Like Dopamine Receptors within the Dentate Gyrus of Hippocampus Decreased the Reinstatement of Morphine-Extinguished Conditioned Place Preference in Rats. Basic and clinical neuroscience. vol 6. issue 2. 2016-06-16. PMID:27307951. |
it is demonstrated that dopamine receptors in dentate gyrus (dg) region of hip have a remarkable function in spatial reward processing. |
2016-06-16 |
2023-08-13 |
rat |
| J Elliott Robinson, Eyal Vardy, Jeffrey F DiBerto, Vladimir I Chefer, Kate L White, Eric W Fish, Meng Chen, Eduardo Gigante, Michael C Krouse, Hui Sun, Annika Thorsell, Bryan L Roth, Markus Heilig, C J Malang. Receptor Reserve Moderates Mesolimbic Responses to Opioids in a Humanized Mouse Model of the OPRM1 A118G Polymorphism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 11. 2016-06-15. PMID:25881115. |
reduced morphine reward in 118gg mice was associated with decreased dopamine release in the nucleus accumbens and reduced effects on gaba release in the ventral tegmental area that were not due to changes in drug potency or efficacy in vitro or receptor-binding affinity. |
2016-06-15 |
2023-08-13 |
mouse |
| Menahem B Doura, Ellen M Unterwal. MicroRNAs Modulate Interactions between Stress and Risk for Cocaine Addiction. Frontiers in cellular neuroscience. vol 10. 2016-06-15. PMID:27303265. |
mirnas function in glucocorticoid signaling and the mesolimbic dopamine reward system, as well as mood disorders related to drug withdrawal. |
2016-06-15 |
2023-08-13 |
Not clear |
| Ryan Ting-A-Kee, Andrew Heinmiller, Derek van der Koo. A proposed resolution to the paradox of drug reward: Dopamine's evolution from an aversive signal to a facilitator of drug reward via negative reinforcement. Neuroscience and biobehavioral reviews. vol 56. 2016-06-02. PMID:26116542. |
a proposed resolution to the paradox of drug reward: dopamine's evolution from an aversive signal to a facilitator of drug reward via negative reinforcement. |
2016-06-02 |
2023-08-13 |
Not clear |
| Ryan Ting-A-Kee, Andrew Heinmiller, Derek van der Koo. A proposed resolution to the paradox of drug reward: Dopamine's evolution from an aversive signal to a facilitator of drug reward via negative reinforcement. Neuroscience and biobehavioral reviews. vol 56. 2016-06-02. PMID:26116542. |
here we propose a resolution to this paradox whereby dopamine - which has traditionally been viewed as a signal of reward - initially signaled aversion and encouraged escape. |
2016-06-02 |
2023-08-13 |
Not clear |
| Amanda M Griffin, H Harrington Cleveland, Gabriel L Schlomer, David J Vandenbergh, Mark E Feinber. Differential Susceptibility: The Genetic Moderation of Peer Pressure on Alcohol Use. Journal of youth and adolescence. vol 44. issue 10. 2016-06-01. PMID:26307243. |
the dopamine receptor d4 gene (drd4) is a potential candidate gene that may influence adolescents' susceptibility to their peer environment due to the role dopamine plays in reward sensation during social interaction. |
2016-06-01 |
2023-08-13 |
Not clear |
| Benjamin T Saunders, Jocelyn M Richard, Patricia H Jana. Contemporary approaches to neural circuit manipulation and mapping: focus on reward and addiction. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 370. issue 1677. 2016-05-31. PMID:26240425. |
here we discuss contemporary approaches for understanding reward and addiction, with a focus on midbrain dopamine and cortico-striato-pallidal circuits. |
2016-05-31 |
2023-08-13 |
Not clear |
| C Biesdorf, A-L Wang, B Topic, D Petri, H Milani, J P Huston, M A de Souza Silv. Dopamine in the nucleus accumbens core, but not shell, increases during signaled food reward and decreases during delayed extinction. Neurobiology of learning and memory. vol 123. 2016-05-26. PMID:26071677. |
dopamine in the nucleus accumbens core, but not shell, increases during signaled food reward and decreases during delayed extinction. |
2016-05-26 |
2023-08-13 |
rat |
| Arif A Hamid, Jeffrey R Pettibone, Omar S Mabrouk, Vaughn L Hetrick, Robert Schmidt, Caitlin M Vander Weele, Robert T Kennedy, Brandon J Aragona, Joshua D Berk. Mesolimbic dopamine signals the value of work. Nature neuroscience. vol 19. issue 1. 2016-05-26. PMID:26595651. |
second-by-second dopamine release encoded an estimate of temporally discounted future reward (a value function). |
2016-05-26 |
2023-08-13 |
Not clear |
| Arif A Hamid, Jeffrey R Pettibone, Omar S Mabrouk, Vaughn L Hetrick, Robert Schmidt, Caitlin M Vander Weele, Robert T Kennedy, Brandon J Aragona, Joshua D Berk. Mesolimbic dopamine signals the value of work. Nature neuroscience. vol 19. issue 1. 2016-05-26. PMID:26595651. |
our results indicate that dopamine conveys a single, rapidly evolving decision variable, the available reward for investment of effort, which is employed for both learning and motivational functions. |
2016-05-26 |
2023-08-13 |
Not clear |
| Chun Yun Chang, Guillem R Esber, Yasmin Marrero-Garcia, Hau-Jie Yau, Antonello Bonci, Geoffrey Schoenbau. Brief optogenetic inhibition of dopamine neurons mimics endogenous negative reward prediction errors. Nature neuroscience. vol 19. issue 1. 2016-05-26. PMID:26642092. |
here we provide evidence in support of the proposed linkage, showing in a modified pavlovian over-expectation task that brief pauses in the firing of dopamine neurons in rat ventral tegmental area at the time of reward are sufficient to mimic the effects of endogenous negative prediction errors. |
2016-05-26 |
2023-08-13 |
rat |
| Giorgio Rizzi, Meredith E Lodge, Kelly R Ta. Design and construction of a low-cost nose poke system for rodents. MethodsX. vol 3. 2016-05-25. PMID:27222822. |
operant behavioral tasks for animals have long been used to probe the function of multiple brain regions (i.e., understanding the role of dopamine in electrical brain stimulation reward [1], or determining the rewarding properties of feeding oriented brain pathways [2]). |
2016-05-25 |
2023-08-13 |
mouse |
| Mark S Gold, Rajendra D Badgaiyan, Kenneth Blu. A Shared Molecular and Genetic Basis for Food and Drug Addiction: Overcoming Hypodopaminergic Trait/State by Incorporating Dopamine Agonistic Therapy in Psychiatry. The Psychiatric clinics of North America. vol 38. issue 3. 2016-05-23. PMID:26300032. |
reward deficiency syndrome describes a hypodopaminergic trait/state that provides a rationale for commonality in approaches for treating long-term reduced dopamine function across the reward brain regions. |
2016-05-23 |
2023-08-13 |
Not clear |
| Kenneth T Kishida, Ignacio Saez, Terry Lohrenz, Mark R Witcher, Adrian W Laxton, Stephen B Tatter, Jason P White, Thomas L Ellis, Paul E M Phillips, P Read Montagu. Subsecond dopamine fluctuations in human striatum encode superposed error signals about actual and counterfactual reward. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 1. 2016-05-13. PMID:26598677. |
subsecond dopamine fluctuations in human striatum encode superposed error signals about actual and counterfactual reward. |
2016-05-13 |
2023-08-13 |
human |
| Kenneth T Kishida, Ignacio Saez, Terry Lohrenz, Mark R Witcher, Adrian W Laxton, Stephen B Tatter, Jason P White, Thomas L Ellis, Paul E M Phillips, P Read Montagu. Subsecond dopamine fluctuations in human striatum encode superposed error signals about actual and counterfactual reward. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 1. 2016-05-13. PMID:26598677. |
one possibility is that this process is the normal behavior of reward processing dopamine neurons, which previously had not been tested by experiments in animal models. |
2016-05-13 |
2023-08-13 |
human |
| Melissa A Stouffer, Catherine A Woods, Jyoti C Patel, Christian R Lee, Paul Witkovsky, Li Bao, Robert P Machold, Kymry T Jones, Soledad Cabeza de Vaca, Maarten E A Reith, Kenneth D Carr, Margaret E Ric. Insulin enhances striatal dopamine release by activating cholinergic interneurons and thereby signals reward. Nature communications. vol 6. 2016-05-11. PMID:26503322. |
insulin enhances striatal dopamine release by activating cholinergic interneurons and thereby signals reward. |
2016-05-11 |
2023-08-13 |
rat |
| Tom P Freeman, Ravi K Das, Sunjeev K Kamboj, H Valerie Curra. Dopamine, urges to smoke, and the relative salience of drug versus non-drug reward. Social cognitive and affective neuroscience. vol 10. issue 1. 2016-05-10. PMID:24526184. |
dopamine, urges to smoke, and the relative salience of drug versus non-drug reward. |
2016-05-10 |
2023-08-12 |
Not clear |
| T M Lancaster, E A Heerey, K Mantripragada, D E J Linde. Replication study implicates COMT val158met polymorphism as a modulator of probabilistic reward learning. Genes, brain, and behavior. vol 14. issue 6. 2016-05-10. PMID:26096878. |
the polymorphism affects dopamine catabolism and thus modulates prefrontal dopamine levels, which may lead to variation in individual responses to risk and reward. |
2016-05-10 |
2023-08-13 |
Not clear |
| Paul F Kramer, John T William. Cocaine Decreases Metabotropic Glutamate Receptor mGluR1 Currents in Dopamine Neurons by Activating mGluR5. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 10. 2016-05-09. PMID:25829143. |
midbrain dopamine neurons are important mediators of reward and movement and are sensitive to cocaine-induced plasticity. |
2016-05-09 |
2023-08-13 |
Not clear |