| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael T Treadway, Jessica A Cooper, Andrew H Mille. Can't or Won't? Immunometabolic Constraints on Dopaminergic Drive. Trends in cognitive sciences. vol 23. issue 5. 2020-09-24. PMID:30948204. |
inflammatory cytokines have been shown to have a direct effect on mesolimbic dopamine (da) that is associated with a reduced willingness to expend effort for reward. |
2020-09-24 |
2023-08-13 |
Not clear |
| Jesse A Mendoza, Christopher K Lafferty, Angela K Yang, Jonathan P Brit. Cue-Evoked Dopamine Neuron Activity Helps Maintain but Does Not Encode Expected Value. Cell reports. vol 29. issue 6. 2020-09-24. PMID:31693885. |
cue-evoked midbrain dopamine (da) neuron activity reflects expected value, but its influence on reward assessment is unclear. |
2020-09-24 |
2023-08-13 |
mouse |
| Robert J Wickham, Makenzie Lehr, Lauryn Mitchell, Nii A Add. Combined Infusion and Stimulation with Fast-Scan Cyclic Voltammetry (CIS-FSCV) to Assess Ventral Tegmental Area Receptor Regulation of Phasic Dopamine. Journal of visualized experiments : JoVE. issue 158. 2020-09-23. PMID:32420985. |
phasic dopamine (da) release from the ventral tegmental area (vta) to the nucleus accumbens plays a pivotal role in reward processing and reinforcement learning. |
2020-09-23 |
2023-08-13 |
rat |
| Kyle Flack, Christopher Pankey, Kelsey Ufholz, LuAnn Johnson, James N Roemmic. Genetic variations in the dopamine reward system influence exercise reinforcement and tolerance for exercise intensity. Behavioural brain research. vol 375. 2020-09-22. PMID:31404557. |
genetic variations in the dopamine reward system influence exercise reinforcement and tolerance for exercise intensity. |
2020-09-22 |
2023-08-13 |
Not clear |
| Navatha Alugubelly, Afzaal N Mohammad, Mariola J Edelmann, Bindu Nanduri, Mohammed Sayed, Juw Won Park, Russell L Car. Proteomic and transcriptional profiling of rat amygdala following social play. Behavioural brain research. vol 376. 2020-09-22. PMID:31493430. |
ipa also revealed that differentially expressed genes/proteins in our data had significant over representation of neurotransmitter signaling systems, including the opioid, serotonin, and dopamine systems, suggesting that play alters the systems involved in the regulation of reward. |
2020-09-22 |
2023-08-13 |
rat |
| Xiaofan Li, Miho Terunuma, Tarek G Deeb, Shari Wiseman, Menelas N Pangalos, Angus C Nairn, Stephen J Moss, Paul A Slesinge. Direct Interaction of PP2A Phosphatase with GABA The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 14. 2020-09-22. PMID:32111696. |
in the ventral tegmental area (vta), the center of the brain's reward circuit, gabaergic neurons control the excitability of dopamine (da) projection neurons and are the site of initial psychostimulant-dependent changes in signaling. |
2020-09-22 |
2023-08-13 |
Not clear |
| Minryung R Song, Sang Wan Le. Dynamic resource allocation during reinforcement learning accounts for ramping and phasic dopamine activity. Neural networks : the official journal of the International Neural Network Society. vol 126. 2020-09-18. PMID:32203877. |
dopamine activity may transition between two patterns: (1) phasic responses to cues and rewards, and (2) ramping activity arising as the agent approaches the reward. |
2020-09-18 |
2023-08-13 |
Not clear |
| Alessandra Porcu, Megan Vaughan, Anna Nilsson, Natsuko Arimoto, Katja Lamia, David K Wels. Vulnerability to helpless behavior is regulated by the circadian clock component CRYPTOCHROME in the mouse nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 24. 2020-09-14. PMID:32487727. |
the nucleus accumbens (nac), a central component of the midbrain dopamine reward circuit, exhibits disturbed circadian rhythms in the postmortem brains of depressed patients. |
2020-09-14 |
2023-08-13 |
mouse |
| Alessandra Porcu, Megan Vaughan, Anna Nilsson, Natsuko Arimoto, Katja Lamia, David K Wels. Vulnerability to helpless behavior is regulated by the circadian clock component CRYPTOCHROME in the mouse nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 24. 2020-09-14. PMID:32487727. |
our data reveal a causal role for cry in regulating the midbrain dopamine reward system, and provide a mechanistic link between the nac circadian clock and vulnerability to depression. |
2020-09-14 |
2023-08-13 |
mouse |
| Lars-Lennart Oettl, Max Scheller, Carla Filosa, Sebastian Wieland, Franziska Haag, Cathrin Loeb, Daniel Durstewitz, Roman Shusterman, Eleonora Russo, Wolfgang Kelsc. Phasic dopamine reinforces distinct striatal stimulus encoding in the olfactory tubercle driving dopaminergic reward prediction. Nature communications. vol 11. issue 1. 2020-08-31. PMID:32651365. |
here we show that phasic dopamine is sufficient to reinforce the distinctness of stimulus representations in the ventral striatum even in the absence of reward. |
2020-08-31 |
2023-08-13 |
Not clear |
| Ian J Bamford, Nigel S Bamfor. The Striatum's Role in Executing Rational and Irrational Economic Behaviors. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 25. issue 5. 2020-08-25. PMID:30678530. |
the convergence of excitatory glutamatergic activity from the thalamus and cortex, along with dopamine release in response to novel stimulation, provide the basis for motor learning, reward seeking, and habit formation. |
2020-08-25 |
2023-08-13 |
Not clear |
| Ivan Trujillo-Pisanty, Kent Conover, Pavel Solis, Daniel Palacios, Peter Shizga. Dopamine neurons do not constitute an obligatory stage in the final common path for the evaluation and pursuit of brain stimulation reward. PloS one. vol 15. issue 6. 2020-08-24. PMID:32502210. |
dopamine neurons do not constitute an obligatory stage in the final common path for the evaluation and pursuit of brain stimulation reward. |
2020-08-24 |
2023-08-13 |
rat |
| Ivan Trujillo-Pisanty, Kent Conover, Pavel Solis, Daniel Palacios, Peter Shizga. Dopamine neurons do not constitute an obligatory stage in the final common path for the evaluation and pursuit of brain stimulation reward. PloS one. vol 15. issue 6. 2020-08-24. PMID:32502210. |
in rats working for direct, optical activation of midbrain dopamine neurons, we varied the strength and opportunity cost of the stimulation and measured time allocation, the proportion of trial time devoted to reward pursuit. |
2020-08-24 |
2023-08-13 |
rat |
| Ivan Trujillo-Pisanty, Kent Conover, Pavel Solis, Daniel Palacios, Peter Shizga. Dopamine neurons do not constitute an obligatory stage in the final common path for the evaluation and pursuit of brain stimulation reward. PloS one. vol 15. issue 6. 2020-08-24. PMID:32502210. |
dopamine neurons are an obligatory stage in the dominant model of icss, which positions them at a key nexus in the final common path for reward seeking. |
2020-08-24 |
2023-08-13 |
rat |
| Ivan Trujillo-Pisanty, Kent Conover, Pavel Solis, Daniel Palacios, Peter Shizga. Dopamine neurons do not constitute an obligatory stage in the final common path for the evaluation and pursuit of brain stimulation reward. PloS one. vol 15. issue 6. 2020-08-24. PMID:32502210. |
this model fails to provide a cogent account for the differential effect of dopamine transporter blockade on the reward mountain. |
2020-08-24 |
2023-08-13 |
rat |
| Jessica K Stanek, Kathryn C Dickerson, Kimberly S Chiew, Nathaniel J Clement, R Alison Adcoc. Expected Reward Value and Reward Uncertainty Have Temporally Dissociable Effects on Memory Formation. Journal of cognitive neuroscience. vol 31. issue 10. 2020-08-21. PMID:30990388. |
these two signatures are a phasic dopamine response immediately following a reward cue that encodes its expected value and a sustained, ramping response that has been demonstrated during high reward uncertainty [fiorillo, c. d., tobler, p. n., & schultz, w. discrete coding of reward probability and uncertainty by dopamine neurons. |
2020-08-21 |
2023-08-13 |
Not clear |
| Ellen T Koch, Lynn A Raymon. Dysfunctional striatal dopamine signaling in Huntington's disease. Journal of neuroscience research. vol 97. issue 12. 2020-08-21. PMID:31304622. |
dopamine signaling in the striatum is critical for a variety of behaviors including movement, behavioral flexibility, response to reward and many forms of learning. |
2020-08-21 |
2023-08-13 |
mouse |
| Yuta Ohg. [Alcohol dependence and opioid receptor -Pharmacological profile of nalmefene]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 155. issue 3. 2020-08-12. PMID:32378631. |
mesolimbic dopamine neuron projecting from ventral tegmental area to nucleus accumbens (reward system) plays important roles in alcohol dependence including other dependence. |
2020-08-12 |
2023-08-13 |
rat |
| K E Linker, S J Cross, F M Lesli. Glial mechanisms underlying substance use disorders. The European journal of neuroscience. vol 50. issue 3. 2020-08-07. PMID:30240518. |
we will also evaluate the evidence demonstrating that glial activation is essential for drug reward and drug-induced dopamine release, and highlight clinical evidence showing that glial mechanisms contribute to drug abuse liability. |
2020-08-07 |
2023-08-13 |
Not clear |
| Mariya V Cherkasova, Jeffrey C Corrow, Alisdair Taylor, Shanna C Yeung, Jacob L Stubbs, Martin J McKeown, Silke Appel-Cresswell, A Jon Stoessl, Jason J S Barto. Dopamine replacement remediates risk aversion in Parkinson's disease in a value-independent manner. Parkinsonism & related disorders. vol 66. 2020-08-04. PMID:31473085. |
some studies have suggested an amplification of subjective reward value, consistent with the role of dopamine in reward value coding. |
2020-08-04 |
2023-08-13 |
Not clear |