| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liang Gong, Cancan He, Yingying Yin, Hui Wang, Qing Ye, Feng Bai, Yonggui Yuan, Haisan Zhang, Luxian Lv, Hongxing Zhang, Zhijun Zhang, Chunming Xi. Mediating Role of the Reward Network in the Relationship between the Dopamine Multilocus Genetic Profile and Depression. Frontiers in molecular neuroscience. vol 10. 2020-09-30. PMID:28959185. |
mediating role of the reward network in the relationship between the dopamine multilocus genetic profile and depression. |
2020-09-30 |
2023-08-13 |
human |
| Adrian G Fischer, Markus Ullsperge. An Update on the Role of Serotonin and its Interplay with Dopamine for Reward. Frontiers in human neuroscience. vol 11. 2020-09-30. PMID:29075184. |
an update on the role of serotonin and its interplay with dopamine for reward. |
2020-09-30 |
2023-08-13 |
mouse |
| Adrian G Fischer, Markus Ullsperge. An Update on the Role of Serotonin and its Interplay with Dopamine for Reward. Frontiers in human neuroscience. vol 11. 2020-09-30. PMID:29075184. |
the specific role of serotonin and its interplay with dopamine (da) in adaptive, reward guided behavior as well as drug dependance, still remains elusive. |
2020-09-30 |
2023-08-13 |
mouse |
| Beth Ann Rice, Raza Tariq, Chana K Akin. Intramuscular Route of Administration Increases Potency in Eliciting Cocaine-Induced Behavioral Sensitization. Current psychopharmacology. vol 6. issue 1. 2020-09-30. PMID:29104856. |
in animals, repeated administration of cocaine results in behavioral sensitization which is thought to represent adaptations in the mesolimbic dopamine neural circuitry, the reward pathway. |
2020-09-30 |
2023-08-13 |
Not clear |
| Toshiharu Ichinose, Hiromu Tanimoto, Nobuhiro Yamagat. Behavioral Modulation by Spontaneous Activity of Dopamine Neurons. Frontiers in systems neuroscience. vol 11. 2020-09-30. PMID:29321731. |
besides its well-known phasic firing to natural reward, a substantial number of dopamine neurons (dans) are known to exhibit ongoing intrinsic activity in the absence of an external stimulus. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ahmed Hasbi, Melissa L Perreault, Maurice Y F Shen, Theresa Fan, Tuan Nguyen, Mohammed Alijaniaram, Tomek J Banasikowski, Anthony A Grace, Brian F O'Dowd, Paul J Fletcher, Susan R Georg. Activation of Dopamine D1-D2 Receptor Complex Attenuates Cocaine Reward and Reinstatement of Cocaine-Seeking through Inhibition of DARPP-32, ERK, and ΔFosB. Frontiers in pharmacology. vol 8. 2020-09-30. PMID:29354053. |
activation of dopamine d1-d2 receptor complex attenuates cocaine reward and reinstatement of cocaine-seeking through inhibition of darpp-32, erk, and Δfosb. |
2020-09-30 |
2023-08-13 |
rat |
| Jeffrey J Olney, Shelley M Warlow, Erin E Naffziger, Kent C Berridg. Current perspectives on incentive salience and applications to clinical disorders. Current opinion in behavioral sciences. vol 22. 2020-09-30. PMID:29503841. |
'wanting' refers to incentive salience, a motivation process for reward, and is mediated by larger systems involving mesocorticolimbic dopamine. |
2020-09-30 |
2023-08-13 |
Not clear |
| Roberto Coccurello, Mauro Maccarron. Hedonic Eating and the "Delicious Circle": From Lipid-Derived Mediators to Brain Dopamine and Back. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:29740277. |
thus, the role of midbrain dopamine is positioned at the intersection between selected hormonal signals involved in food reward information processing (namely, leptin, ghrelin, and insulin), and lipid-derived neural mediators such as endocannabinoids. |
2020-09-30 |
2023-08-13 |
Not clear |
| Giorgio Bergamini, Jonas Mechtersheimer, Damiano Azzinnari, Hannes Sigrist, Michaela Buerge, Robert Dallmann, Robert Freije, Afroditi Kouraki, Jolanta Opacka-Juffry, Erich Seifritz, Boris Ferger, Tobias Suter, Christopher R Pryc. Chronic social stress induces peripheral and central immune activation, blunted mesolimbic dopamine function, and reduced reward-directed behaviour in mice. Neurobiology of stress. vol 8. 2020-09-30. PMID:29888303. |
psychosocial stress is a major risk factor for depression, stress leads to peripheral and central immune activation, immune activation is associated with blunted dopamine (da) neural function, da function underlies reward interest, and reduced reward interest is a core symptom of depression. |
2020-09-30 |
2023-08-13 |
mouse |
| Lingli Zhang, Wenfei Han, Chenguanlu Lin, Fei Li, Ivan E de Arauj. Sugar Metabolism Regulates Flavor Preferences and Portal Glucose Sensing. Frontiers in integrative neuroscience. vol 12. 2020-09-30. PMID:30519164. |
consistently, intra-portal infusions of glucose, but not of mdg, induced significant rises in dopamine (da) levels within brain reward circuits. |
2020-09-30 |
2023-08-13 |
mouse |
| Kyoung Kon Ki. Understanding the Mechanism of Action and Clinical Implications of Anti-Obesity Drugs Recently Approved in Korea. Korean journal of family medicine. vol 40. issue 2. 2020-09-30. PMID:30929417. |
the hypophagic effect of liraglutide is mediated through the direct activation of pomc/cart neurons and the indirect suppression of npy/agrp neurons through γ-aminobutyric acid-dependent signaling, with adjunctive suppression of the mesolimbic dopamine reward system. |
2020-09-30 |
2023-08-13 |
Not clear |
| Victoria B Velásquez, Gabriel A Zamorano, Jonathan Martínez-Pinto, Christian Bonansco, Pablo Jara, Gonzalo E Torres, Georgina M Renard, Ramón Sotomayor-Zárat. Programming of Dopaminergic Neurons by Early Exposure to Sex Hormones: Effects on Morphine-Induced Accumbens Dopamine Release, Reward, and Locomotor Behavior in Male and Female Rats. Frontiers in pharmacology. vol 10. 2020-09-30. PMID:30971928. |
programming of dopaminergic neurons by early exposure to sex hormones: effects on morphine-induced accumbens dopamine release, reward, and locomotor behavior in male and female rats. |
2020-09-30 |
2023-08-13 |
rat |
| Jamie A Burns, Danielle S Kroll, Dana E Feldman, Christopher Kure Liu, Peter Manza, Corinde E Wiers, Nora D Volkow, Gene-Jack Wan. Molecular Imaging of Opioid and Dopamine Systems: Insights Into the Pharmacogenetics of Opioid Use Disorders. Frontiers in psychiatry. vol 10. 2020-09-30. PMID:31620026. |
here, we review the current molecular imaging literature to assess how genetic variations in the opioid and dopamine systems affect function in the brain's reward, cognition, and stress pathways, potentially resulting in vulnerabilities to oud. |
2020-09-30 |
2023-08-13 |
Not clear |
| Sarah C Akerman, Mary F Brunette, Douglas L Noordsy, Alan I Gree. Pharmacotherapy of Co-Occurring Schizophrenia and Substance Use Disorders. Current addiction reports. vol 1. issue 4. 2020-09-29. PMID:27226947. |
we also discuss a neurobiological formulation suggesting that the cooccurrence of these disorders may be related to a dysfunction in the dopamine mediated brain reward circuitry. |
2020-09-29 |
2023-08-13 |
Not clear |
| Andrew D Peckham, Sheri L Johnso. Spontaneous Eye-Blink Rate as an Index of Reward Responsivity: Validation and Links to Bipolar Disorder. Clinical psychological science : a journal of the Association for Psychological Science. vol 4. issue 3. 2020-09-29. PMID:27274949. |
extensive research supports the role of striatal dopamine in pursuing and responding to reward, and that eye-blink rate is a valid indicator of striatal dopamine. |
2020-09-29 |
2023-08-13 |
human |
| Benjamin C Nephew, Christopher Murgatroyd, Florent Pittet, Marcelo Feb. Brain Reward Pathway Dysfunction in Maternal Depression and Addiction: A Present and Future Transgenerational Risk. Journal of reward deficiency syndrome. vol 1. issue 3. 2020-09-29. PMID:27617302. |
postpartum depression and drug use disorders may entail alterations in the reward pathway, particularly in striatal and prefrontal areas, which may affect maternal attachment to offspring and heighten the risk of transgenerational effects on the oxytocin and dopamine systems. |
2020-09-29 |
2023-08-13 |
Not clear |
| Kenneth Blum, Rajendra D Badgaiyan, Eric R Braverman, Kristina Dushaj, Mona Li, Peter K Thanos, Zsolt Demetrovics, Marcelo Feb. Hypothesizing that, A Pro-Dopamine Regulator (KB220Z) Should Optimize, but Not Hyper-Activate the Activity of Trace Amine-Associated Receptor 1 (TAAR-1) and Induce Anti-Craving of Psychostimulants in the Long-Term. Journal of reward deficiency syndrome and addiction science. vol 2. issue 1. 2020-09-29. PMID:28317038. |
based on many studies, it is accepted that in reward deficiency syndrome (rds), there is weakened tonic and improved phasic dopamine discharge leading to a hypodopaminergic/glutamatergic trait. |
2020-09-29 |
2023-08-13 |
Not clear |
| Maciej Bieliński, Marcin Jaracz, Natalia Lesiewska, Marta Tomaszewska, Marcin Sikora, Roman Junik, Anna Kamińska, Andrzej Tretyn, Alina Borkowsk. Association between Neuropsychiatric disease and treatment. vol 13. 2020-09-29. PMID:28860780. |
abnormalities in dopamine signaling involved in the reward circuit may ensue excessive consumption of food, resulting in obesity and leading to neuropsychiatric disorders such as depression. |
2020-09-29 |
2023-08-13 |
Not clear |
| Yan-Feng Zhang, Stephanie J Crag. Pauses in Striatal Cholinergic Interneurons: What is Revealed by Their Common Themes and Variations? Frontiers in systems neuroscience. vol 11. 2020-09-29. PMID:29163075. |
the respective pause responses observed can demonstrate many commonalities, such as constant latency and duration, synchronous occurrence in a population of cells, and coincidence with phasic activities of midbrain dopamine neurons (dans) that signal reward predictions and errors. |
2020-09-29 |
2023-08-13 |
Not clear |
| Michelle A Sahai, Colin Davidson, Neelakshi Dutta, Jolanta Opacka-Juffr. Mechanistic Insights into the Stimulant Properties of Novel Psychoactive Substances (NPS) and Their Discrimination by the Dopamine Transporter-In Silico and In Vitro Exploration of Dissociative Diarylethylamines. Brain sciences. vol 8. issue 4. 2020-09-29. PMID:29642450. |
stimulants normally act at the dopamine transporter (dat) and thus increase dopamine (da) availability in the brain, including nucleus accumbens, within the reward and addiction pathway. |
2020-09-29 |
2023-08-13 |
rat |