| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Philipp Homan, Miklos Argyelan, Christina L Fales, Anita D Barber, Pamela DeRosse, Philip R Szeszko, Delbert G Robinson, Todd Lencz, Anil K Malhotr. Striatal volume and functional connectivity correlate with weight gain in early-phase psychosis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 11. 2020-07-06. PMID:31315130. |
even though other receptors are also implicated, the dorsal striatum, rich in dopamine d2 receptors, which are antagonized by antipsychotic medications, plays a key role in the human reward system and in appetite regulation, suggesting that altered dopamine activity in the striatal reward circuitry may be responsible for increased food craving and weight gain. |
2020-07-06 |
2023-08-13 |
human |
| Alexis E Whitton, Jenna M Reinen, Mark Slifstein, Yuen-Siang Ang, Patrick J McGrath, Dan V Iosifescu, Anissa Abi-Dargham, Diego A Pizzagalli, Franklin R Schneie. Baseline reward processing and ventrostriatal dopamine function are associated with pramipexole response in depression. Brain : a journal of neurology. vol 143. issue 2. 2020-07-06. PMID:32040562. |
baseline reward processing and ventrostriatal dopamine function are associated with pramipexole response in depression. |
2020-07-06 |
2023-08-13 |
Not clear |
| Alexis E Whitton, Jenna M Reinen, Mark Slifstein, Yuen-Siang Ang, Patrick J McGrath, Dan V Iosifescu, Anissa Abi-Dargham, Diego A Pizzagalli, Franklin R Schneie. Baseline reward processing and ventrostriatal dopamine function are associated with pramipexole response in depression. Brain : a journal of neurology. vol 143. issue 2. 2020-07-06. PMID:32040562. |
the efficacy of dopamine agonists in treating major depressive disorder has been hypothesized to stem from effects on ventrostriatal dopamine and reward function. |
2020-07-06 |
2023-08-13 |
Not clear |
| Alexis E Whitton, Jenna M Reinen, Mark Slifstein, Yuen-Siang Ang, Patrick J McGrath, Dan V Iosifescu, Anissa Abi-Dargham, Diego A Pizzagalli, Franklin R Schneie. Baseline reward processing and ventrostriatal dopamine function are associated with pramipexole response in depression. Brain : a journal of neurology. vol 143. issue 2. 2020-07-06. PMID:32040562. |
this study evaluated whether measures of reward processing and ventrostriatal dopamine function predicted response to the dopamine agonist, pramipexole (clinicaltrials.gov identifier: nct02033369). |
2020-07-06 |
2023-08-13 |
Not clear |
| Christopher Laurence Souders, Robert H Davis, Hua Qing, Xuefang Liang, Marcelo Febo, Christopher J Martyniu. The psychoactive cathinone derivative pyrovalerone alters locomotor activity and decreases dopamine receptor expression in zebrafish (Danio rerio). Brain and behavior. vol 9. issue 11. 2020-07-01. PMID:31625691. |
the primary mechanism of action of cathinones is to inhibit reuptake transporters (dopamine and norepinephrine) in reward centers of the central nervous system. |
2020-07-01 |
2023-08-13 |
zebrafish |
| Yam R Giri, Sachidanand R Peter. Escalation of Gambling Associated With Aripiprazole: A Case Report and Literature Review. Journal of psychiatric practice. vol 25. issue 2. 2020-06-19. PMID:30849063. |
it is postulated that aripiprazole may cause impulse-control problems because it can produce a hyperdopaminergic state in the mesolimbic pathway (reward system) through its predominant action on dopamine d3 receptors. |
2020-06-19 |
2023-08-13 |
Not clear |
| Linda D Simmler, Randy D Blakel. The SERT Met172 Mouse: An Engineered Model To Elucidate the Contributions of Serotonin Signaling to Cocaine Action. ACS chemical neuroscience. vol 10. issue 7. 2020-06-11. PMID:30817127. |
it is well-known that essential aspects of cocaine's addictive actions involve the drug's ability to block the presynaptic dopamine (da) transporter (dat), thereby elevating extracellular levels of da in brain circuits that subserve reward, reinforcement, and habit. |
2020-06-11 |
2023-08-13 |
mouse |
| Lotfi Khemiri, Pia Steensland, Joar Guterstam, Örjan de Manzano, Johan Franck, Nitya Jayaram-Lindströ. Effects of the monoamine stabilizer (-)OSU6162 on cognitive function in alcohol dependence. Psychopharmacology. vol 237. issue 1. 2020-06-04. PMID:31628507. |
alcohol dependence (ad) is associated with a dysregulated mesolimbocortical dopamine system-a pathway which is also implicated in both reward and cognition. |
2020-06-04 |
2023-08-13 |
rat |
| Robyn St Laurent, Julie Kaue. Synaptic Plasticity at Inhibitory Synapses in the Ventral Tegmental Area Depends upon Stimulation Site. eNeuro. vol 6. issue 6. 2020-06-03. PMID:31619451. |
several cellular adaptations have been described in the ventral tegmental area (vta), a central component of the reward pathway that is the major source of dopamine release. |
2020-06-03 |
2023-08-13 |
mouse |
| Sweyta Lohani, Adria K Martig, Karl Deisseroth, Ilana B Witten, Bita Moghadda. Dopamine Modulation of Prefrontal Cortex Activity Is Manifold and Operates at Multiple Temporal and Spatial Scales. Cell reports. vol 27. issue 1. 2020-06-01. PMID:30943418. |
although the function of dopamine in subcortical structures is largely limited to reward and movement, dopamine neurotransmission in the prefrontal cortex (pfc) is critical to a multitude of temporally and functionally diverse processes, such as attention, working memory, behavioral flexibility, action planning, and sustained motivational and affective states. |
2020-06-01 |
2023-08-13 |
Not clear |
| Akanksha Mishra, Sonu Singh, Virendra Tiwari, Swati Chaturvedi, M Wahajuddin, Shubha Shukl. Dopamine receptor activation mitigates mitochondrial dysfunction and oxidative stress to enhance dopaminergic neurogenesis in 6-OHDA lesioned rats: A role of Wnt signalling. Neurochemistry international. vol 129. 2020-06-01. PMID:31078578. |
dopamine system regulates different aspects of behavioural phenotypes such as motor control, reward, anxiety and depression via acting on dopamine receptors (d1-d5). |
2020-06-01 |
2023-08-13 |
rat |
| L Cinnamon Bidwell, Hollis C Karoly, Rachel E Thayer, Eric D Claus, Angela D Bryan, Barbara J Weiland, Sophie YorkWilliams, Kent E Hutchiso. DRD2 promoter methylation and measures of alcohol reward: functional activation of reward circuits and clinical severity. Addiction biology. vol 24. issue 3. 2020-05-18. PMID:29464814. |
we hypothesized that epigenetic alterations in the promoter region of the dopamine d2 receptor (drd2) gene would be associated with cue-elicited activation of neural reward regions, as well as severity of alcohol use behavior. |
2020-05-18 |
2023-08-13 |
Not clear |
| Fumiya Shinohara, Yuta Asaoka, Hironori Kamii, Masabumi Minami, Katsuyuki Kaned. Stress augments the rewarding memory of cocaine via the activation of brainstem-reward circuitry. Addiction biology. vol 24. issue 3. 2020-05-18. PMID:29480583. |
these findings suggest a mechanism wherein the ldt is activated by noradrenergic input from the locus coeruleus, leading to the activation of vta dopamine neurons via both cholinergic and glutamatergic transmission and the subsequent excitation of the mpfc to enhance the memory of cocaine-induced reward value. |
2020-05-18 |
2023-08-13 |
rat |
| Naoyasu Hirao, Madoka Noriuchi, Hiroko Isobe, Yoshiaki Kikuch. Luxury Cues Facilitate the Connection Between Social Dominance and Reward Mediated by the Lateral Prefrontal Cortex. Journal of cosmetic science. vol 71. issue 1. 2020-05-18. PMID:32271707. |
these results suggest that the neural substrate of the effects is based on both the dopamine reward system and the self-other distinction system involved in social dominance and that the right dlpfc plays a critical role in the association between these systems. |
2020-05-18 |
2023-08-13 |
human |
| Selina A Wolke, Mitul A Mehta, Owen O'Daly, Fernando Zelaya, Nada Zahreddine, Hanna Keren, Georgia O'Callaghan, Allan H Young, Ellen Leibenluft, Daniel S Pine, Argyris Stringari. Modulation of anterior cingulate cortex reward and penalty signalling in medication-naive young-adult subjects with depressive symptoms following acute dose lurasidone. Psychological medicine. vol 49. issue 8. 2020-05-14. PMID:30606271. |
aberrations in reward and penalty processing are implicated in depression and putatively reflect altered dopamine signalling. |
2020-05-14 |
2023-08-13 |
human |
| Zhi Li, Yi Wang, Chao Yan, Eric F C Cheung, Anna R Docherty, Pak C Sham, Raquel E Gur, Ruben C Gur, Raymond C K Cha. Inheritance of Neural Substrates for Motivation and Pleasure. Psychological science. vol 30. issue 8. 2020-05-07. PMID:31318629. |
despite advances in the understanding of the reward system and the role of dopamine in recent decades, the heritability of the underlying neural mechanisms is not known. |
2020-05-07 |
2023-08-13 |
human |
| Ryan W Logan, Puja K Parekh, Gabrielle N Kaplan, Darius D Becker-Krail, Wilbur P Williams, Shintaro Yamaguchi, Jun Yoshino, Micah A Shelton, Xiyu Zhu, Hui Zhang, Spencer Waplinger, Ethan Fitzgerald, Jeffrey Oliver-Smith, Poornima Sundarvelu, John F Enwright, Yanhua H Huang, Colleen A McClun. NAD+ cellular redox and SIRT1 regulate the diurnal rhythms of tyrosine hydroxylase and conditioned cocaine reward. Molecular psychiatry. vol 24. issue 11. 2020-05-04. PMID:29728703. |
taken together, we find that rhythms in cellular metabolism and circadian proteins work together to regulate dopamine synthesis and the reward value for drugs of abuse. |
2020-05-04 |
2023-08-13 |
Not clear |
| Márcio Bonesso Alves, Daniela Pereira Laureano, Roberta Dalle Molle, Tania Diniz Machado, Ana Paula de Ascenção Salvador, Patrícia Maidana Miguel, Derek Lupinsky, Carla Dalmaz, Patrícia Pelufo Silveir. Intrauterine growth restriction increases impulsive behavior and is associated with altered dopamine transmission in both medial prefrontal and orbitofrontal cortex in female rats. Physiology & behavior. vol 204. 2020-05-04. PMID:30880239. |
here we investigated the impulsive behavior toward a delayed reward and evaluated dopamine levels and its receptors in the medial prefrontal (mpfc) and orbitofrontal (ofc) cortex of female adult rats exposed to iugr. |
2020-05-04 |
2023-08-13 |
rat |
| Will Dabney, Zeb Kurth-Nelson, Naoshige Uchida, Clara Kwon Starkweather, Demis Hassabis, Rémi Munos, Matthew Botvinic. A distributional code for value in dopamine-based reinforcement learning. Nature. vol 577. issue 7792. 2020-05-04. PMID:31942076. |
since its introduction, the reward prediction error theory of dopamine has explained a wealth of empirical phenomena, providing a unifying framework for understanding the representation of reward and value in the brain |
2020-05-04 |
2023-08-13 |
Not clear |
| James E McCutcheon, Mitchell F Roitma. Mode of Sucrose Delivery Alters Reward-Related Phasic Dopamine Signals in Nucleus Accumbens. ACS chemical neuroscience. vol 10. issue 4. 2020-04-24. PMID:30156402. |
thus, dopamine responses to pellets, infusions as well as predictive cues suggest a nuanced role for dopamine in both reward seeking and reward evaluation. |
2020-04-24 |
2023-08-13 |
human |