| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bowen J Fung, Elissa Sutlief, Marshall G Hussain Shule. Dopamine and the interdependency of time perception and reward. Neuroscience and biobehavioral reviews. vol 125. 2021-06-28. PMID:33652021. |
another stream of literature implicates dopamine in reward and motivation processes. |
2021-06-28 |
2023-08-13 |
human |
| Amanda Elton, Monica L Faulkner, Donita L Robinson, Charlotte A Boettige. Acute depletion of dopamine precursors in the human brain: effects on functional connectivity and alcohol attentional bias. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 8. 2021-06-28. PMID:33727642. |
the results support a substantial role for dopamine in ab, and suggest specific dopamine-modulated functional connections between frontal, limbic, striatal, and brainstem regions mediate general reward ab versus alcohol ab. |
2021-06-28 |
2023-08-13 |
human |
| Aimilia Lydia Kalafateli, Cajsa Aranäs, Elisabet Jerlha. Activation of the amylin pathway modulates cocaine-induced activation of the mesolimbic dopamine system in male mice. Hormones and behavior. vol 127. 2021-06-25. PMID:33166561. |
we therefore explored in male mice, the effects of systemic administration of sct on cocaine-induced locomotor stimulation, dopamine release in the nac and cocaine reward, as well as reward-dependent memory of cocaine, in the conditioned place preference (cpp) paradigm. |
2021-06-25 |
2023-08-13 |
mouse |
| Ewa Galaj, Robert Ranald. Neurobiology of reward-related learning. Neuroscience and biobehavioral reviews. vol 124. 2021-06-25. PMID:33581225. |
our neurobiological model is predicated on the hebbian idea that concurrent synaptic activity on the primary reward neural substrate-proposed to be ventral tegmental area (vta) dopamine (da) neurons-strengthens the synapses involved. |
2021-06-25 |
2023-08-13 |
Not clear |
| T C Peixoto, E G Moura, P N Soares, V S T Rodrigues, S Claudio-Neto, E Oliveira, A C Manhães, P C Lisbo. Nicotine exposure during lactation causes disruption of hedonic eating behavior and alters dopaminergic system in adult female rats. Appetite. vol 160. 2021-06-24. PMID:33453337. |
nicotine is transferred through milk and alters the dopaminergic reward system of adult male rats, reducing dopamine action in the nucleus accumbens (nac) and hypothalamic arcuate nucleus. |
2021-06-24 |
2023-08-13 |
rat |
| Jochen Michely, Shivakumar Viswanathan, Tobias U Hauser, Laura Delker, Raymond J Dolan, Christian Grefke. The role of dopamine in dynamic effort-reward integration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 9. 2021-06-23. PMID:32268344. |
when deciding to act, the neurotransmitter dopamine is implicated in a valuation of prospective effort and reward. |
2021-06-23 |
2023-08-13 |
human |
| Jochen Michely, Shivakumar Viswanathan, Tobias U Hauser, Laura Delker, Raymond J Dolan, Christian Grefke. The role of dopamine in dynamic effort-reward integration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 9. 2021-06-23. PMID:32268344. |
we show that modulating homoeostatic dopamine balance distinctly alters implicit and explicit effort allocation as a function of instantaneous reward. |
2021-06-23 |
2023-08-13 |
human |
| Jochen Michely, Shivakumar Viswanathan, Tobias U Hauser, Laura Delker, Raymond J Dolan, Christian Grefke. The role of dopamine in dynamic effort-reward integration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 9. 2021-06-23. PMID:32268344. |
conversely, pharmacological blockade of dopamine attenuated sensitivity to differences in reward context, reflected in reduced strategic effort discounting. |
2021-06-23 |
2023-08-13 |
human |
| Jochen Michely, Shivakumar Viswanathan, Tobias U Hauser, Laura Delker, Raymond J Dolan, Christian Grefke. The role of dopamine in dynamic effort-reward integration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 9. 2021-06-23. PMID:32268344. |
these findings implicate dopamine in an integration of momentary physical experience and instantaneous reward, suggesting a key role of dopamine in acting to maximise reward on the fly. |
2021-06-23 |
2023-08-13 |
human |
| Riccardo Dore, Regina Krotenko, Jan Philipp Reising, Luca Murru, Sivaraj Mohana Sundaram, Alessandro Di Spiezio, Helge Müller-Fielitz, Markus Schwaninger, Olaf Jöhren, Jens Mittag, Maria Passafaro, Marya Shanabrough, Tamas L Horvath, Carla Schulz, Hendrik Lehner. Nesfatin-1 decreases the motivational and rewarding value of food. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 10. 2021-06-23. PMID:32353862. |
we next adopted a 2-bottle choice procedure, whereby the reward value of sucrose was compared with that of a reference stimulus (sucralose + optogenetic stimulation of vta dopamine neurons) and found that nesfatin-1 fully abolishes the fasting-induced increase in the reward value of sucrose. |
2021-06-23 |
2023-08-13 |
Not clear |
| Ludivine Canchy, Paul Girardeau, Audrey Durand, Caroline Vouillac-Mendoza, Serge H Ahme. Pharmacokinetics trumps pharmacodynamics during cocaine choice: a reconciliation with the dopamine hypothesis of addiction. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 2. 2021-06-23. PMID:32731253. |
first, a systematic literature analysis revealed that the delays of effects of intravenous cocaine on nucleus accumbens dopamine are of the order of tens of seconds and are considerably longer than those of nondrug reward. |
2021-06-23 |
2023-08-13 |
rat |
| Ludivine Canchy, Paul Girardeau, Audrey Durand, Caroline Vouillac-Mendoza, Serge H Ahme. Pharmacokinetics trumps pharmacodynamics during cocaine choice: a reconciliation with the dopamine hypothesis of addiction. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 2. 2021-06-23. PMID:32731253. |
overall, this study suggests that cocaine is indeed supranormal in reward magnitude, as postulated by the dopamine hypothesis of addiction, but is less preferred during choice because its pharmacokinetics makes it an inherently more delayed reward than the alternative. |
2021-06-23 |
2023-08-13 |
rat |
| Joyce P M van der Vegt, Oliver J Hulme, Kristoffer H Madsen, Carsten Buhmann, Bastiaan R Bloem, Alexander Münchau, Rick C Helmich, Hartwig R Siebne. Dopamine agonist treatment increases sensitivity to gamble outcomes in the hippocampus in de novo Parkinson's disease. NeuroImage. Clinical. vol 28. 2021-06-23. PMID:32798910. |
parkinson's disease is associated with severe nigro-striatal dopamine depletion, leading to motor dysfunction and altered reward processing. |
2021-06-23 |
2023-08-13 |
Not clear |
| Maria F Fernandes, David Lau, Sandeep Sharma, Stephanie Fulto. Anxiety-like behavior in female mice is modulated by STAT3 signaling in midbrain dopamine neurons. Brain, behavior, and immunity. vol 95. 2021-06-23. PMID:33872705. |
stat3 activation plays a pivotal role in the behavioral responses to the adiposity hormone leptin, including in midbrain dopamine (da) neurons where it mediates the influence of leptin to diminish physical activity and running reward in male mice. |
2021-06-23 |
2023-08-13 |
mouse |
| Marjorie C Gondré-Lewis, Rosemary Bassey, Kenneth Blu. Pre-clinical models of reward deficiency syndrome: A behavioral octopus. Neuroscience and biobehavioral reviews. vol 115. 2021-06-21. PMID:32360413. |
individuals with mood disorders or with addiction, impulsivity and some personality disorders can share in common a dysfunction in how the brain perceives reward, where processing of natural endorphins or the response to exogenous dopamine stimulants is impaired. |
2021-06-21 |
2023-08-13 |
Not clear |
| Ewa Galaj, Amy Hauck Newman, Zheng-Xiong X. Dopamine D3 receptor-based medication development for the treatment of opioid use disorder: Rationale, progress, and challenges. Neuroscience and biobehavioral reviews. vol 114. 2021-06-21. PMID:32376243. |
in this review, we first review recent progress in research of the dopamine hypothesis of opioid reward and abuse and then describe the rationale and recent development of d3r ligands for the treatment of oud. |
2021-06-21 |
2023-08-13 |
Not clear |
| Heather E Webber, Paula Lopez-Gamundi, Sydney N Stamatovich, Harriet de Wit, Margaret C Wardl. Using pharmacological manipulations to study the role of dopamine in human reward functioning: A review of studies in healthy adults. Neuroscience and biobehavioral reviews. vol 120. 2021-06-21. PMID:33202256. |
using pharmacological manipulations to study the role of dopamine in human reward functioning: a review of studies in healthy adults. |
2021-06-21 |
2023-08-13 |
human |
| Heather E Webber, Paula Lopez-Gamundi, Sydney N Stamatovich, Harriet de Wit, Margaret C Wardl. Using pharmacological manipulations to study the role of dopamine in human reward functioning: A review of studies in healthy adults. Neuroscience and biobehavioral reviews. vol 120. 2021-06-21. PMID:33202256. |
dopamine (da) plays a key role in reward processing and is implicated in psychological disorders such as depression, substance use, and schizophrenia. |
2021-06-21 |
2023-08-13 |
human |
| Kathleen S Lynch, Michael J Rya. Understanding the Role of Incentive Salience in Sexual Decision-Making. Integrative and comparative biology. vol 60. issue 3. 2021-06-17. PMID:32483613. |
we examine studies of dopamine and the mesolimbic reward system because these may play a role in expanding the female's perceptual landscape for novelty in male courtship signals and establishing novel hidden preferences. |
2021-06-17 |
2023-08-13 |
Not clear |
| Hiroki Moriya, Mikael Tiger, Amane Tateno, Takeshi Sakayori, Takahiro Masuoka, WooChan Kim, Ryosuke Arakawa, Yoshiro Okub. Low dopamine transporter binding in the nucleus accumbens in geriatric patients with severe depression. Psychiatry and clinical neurosciences. vol 74. issue 8. 2021-06-09. PMID:32363761. |
especially, mdd in geriatric patients is characterized by anhedonia, which is assumed to be associated with reduced dopamine neurotransmission in the reward system. |
2021-06-09 |
2023-08-13 |
Not clear |