| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kate Z Peters, Joseph F Cheer, Raffaella Tonin. Modulating the Neuromodulators: Dopamine, Serotonin, and the Endocannabinoid System. Trends in neurosciences. vol 44. issue 6. 2021-08-18. PMID:33674134. |
dopamine (da), serotonin (5-hydroxytryptamine, 5-ht), and endocannabinoids (ecs) are key neuromodulators involved in many aspects of motivated behavior, including reward processing, reinforcement learning, and behavioral flexibility. |
2021-08-18 |
2023-08-13 |
Not clear |
| Anna Parvopassu, Maurizio Oggiano, Fabiana Festucci, Giuseppe Curcio, Enrico Alleva, Walter Adrian. Altering the development of the dopaminergic system through social play in rats: Implications for anxiety, depression, hyperactivity, and compulsivity. Neuroscience letters. vol 760. 2021-08-17. PMID:34197903. |
dopamine is essential to many functions like reward, motivation, and attention; when its neural pathways do not function properly, various disorders (e.g., anxiety, depression, hyperactivity, compulsions) can arise. |
2021-08-17 |
2023-08-13 |
human |
| Polina Kosillo, Helen S Bateu. Dopaminergic Dysregulation in Syndromic Autism Spectrum Disorders: Insights From Genetic Mouse Models. Frontiers in neural circuits. vol 15. 2021-08-17. PMID:34366796. |
the dopamine hypothesis of asd postulates that dysregulation of dopaminergic projection pathways could contribute to the behavioral manifestations of asd, including altered reward value of social stimuli, changes in sensorimotor processing, and motor stereotypies. |
2021-08-17 |
2023-08-13 |
mouse |
| Bree A Humburg, Chloe J Jordan, Hai-Ying Zhang, Hui Shen, Xiao Han, Guo-Hua Bi, Briana Hempel, Ewa Galaj, Michael H Baumann, Zheng-Xiong X. Optogenetic brain-stimulation reward: A new procedure to re-evaluate the rewarding versus aversive effects of cannabinoids in dopamine transporter-Cre mice. Addiction biology. vol 26. issue 4. 2021-08-16. PMID:33538103. |
optogenetic brain-stimulation reward: a new procedure to re-evaluate the rewarding versus aversive effects of cannabinoids in dopamine transporter-cre mice. |
2021-08-16 |
2023-08-13 |
mouse |
| Moriya Weitz, Alaa Khayat, Rami Yak. GABAergic projections to the ventral tegmental area govern cocaine-conditioned reward. Addiction biology. vol 26. issue 4. 2021-08-16. PMID:33638301. |
elevated dopamine (da) levels in the reward system underlie various drug-related behaviors, including addiction. |
2021-08-16 |
2023-08-13 |
Not clear |
| Li Yang, Ming Chen, Qianqian Ma, Huan Sheng, Dongyang Cui, Da Shao, Bin Lai, Ping Zhen. Morphine selectively disinhibits glutamatergic input from mPFC onto dopamine neurons of VTA, inducing reward. Neuropharmacology. vol 176. 2021-08-13. PMID:32679049. |
morphine selectively disinhibits glutamatergic input from mpfc onto dopamine neurons of vta, inducing reward. |
2021-08-13 |
2023-08-13 |
Not clear |
| Lauren C Smith, Olivier Georg. Advances in smoking cessation pharmacotherapy: Non-nicotinic approaches in animal models. Neuropharmacology. vol 178. 2021-08-12. PMID:32758566. |
cannabinoid receptor agonists and antagonists interact with the dopamine reward pathway and show efficacy in reducing nicotine addiction-like behaviors in preclinical studies. |
2021-08-12 |
2023-08-13 |
Not clear |
| K P Siju, Vilim Štih, Sophie Aimon, Julijana Gjorgjieva, Ruben Portugues, Ilona C Grunwald Kado. Valence and State-Dependent Population Coding in Dopaminergic Neurons in the Fly Mushroom Body. Current biology : CB. vol 30. issue 11. 2021-08-10. PMID:32386530. |
one neuromodulator, dopamine, has been studied extensively in its role as a reward signal during learning and memory across animal species. |
2021-08-10 |
2023-08-13 |
drosophila_melanogaster |
| Shih-Hsien Lin, Mei Hung Chi, I Hui Lee, Kao Chin Chen, Ying Chun Tai, Wei Jen Yao, Nan Tsing Chiu, Dong-Yu Yang, Chun-Yu Lin, Po See Chen, Yen Kuang Yan. A pilot study on the association between the blood oxygen level-dependent signal in the reward system and dopamine transporter availability in adults with attention deficit hyperactivity disorder. CNS spectrums. vol 26. issue 3. 2021-08-09. PMID:32308185. |
a pilot study on the association between the blood oxygen level-dependent signal in the reward system and dopamine transporter availability in adults with attention deficit hyperactivity disorder. |
2021-08-09 |
2023-08-13 |
Not clear |
| Derrick Butler, David Moore, Nicholas R Glavin, Joshua A Robinson, Aida Ebrahim. Facile Post-deposition Annealing of Graphene Ink Enables Ultrasensitive Electrochemical Detection of Dopamine. ACS applied materials & interfaces. vol 13. issue 9. 2021-07-26. PMID:33645208. |
a growing body of research focuses on engineering materials for electrochemical detection of dopamine (da), a critical neurotransmitter involved in motor function, reward processes, and blood pressure regulation. |
2021-07-26 |
2023-08-13 |
Not clear |
| Horia Pribiag, Sora Shin, Eric Hou-Jen Wang, Fangmiao Sun, Paul Datta, Alexander Okamoto, Hayden Guss, Akanksha Jain, Xiao-Yun Wang, Bruna De Freitas, Patrick Honma, Stefan Pate, Varoth Lilascharoen, Yulong Li, Byung Kook Li. Ventral pallidum DRD3 potentiates a pallido-habenular circuit driving accumbal dopamine release and cocaine seeking. Neuron. vol 109. issue 13. 2021-07-23. PMID:34048697. |
however, how circuit-specific, drug-induced molecular and cellular plasticity can have distributed effects on the mesolimbic dopamine reward system to facilitate relapse to drug use is not fully elucidated. |
2021-07-23 |
2023-08-13 |
Not clear |
| Zoran Madzarac, Lucija Tudor, Marina Sagud, Gordana Nedic Erjavec, Alma Mihaljevic Peles, Nela Piva. The Associations between COMT and MAO-B Genetic Variants with Negative Symptoms in Patients with Schizophrenia. Current issues in molecular biology. vol 43. issue 2. 2021-07-22. PMID:34287249. |
these symptoms are associated with cortical hypodopamynergia and impaired striatal dopamine release in response to reward stimuli. |
2021-07-22 |
2023-08-13 |
Not clear |
| Sophie Lakard, Ileana-Alexandra Pavel, Boris Lakar. Electrochemical Biosensing of Dopamine Neurotransmitter: A Review. Biosensors. vol 11. issue 6. 2021-07-21. PMID:34204902. |
dopamine is one of the most important catecholamine neurotransmitters since it is involved in many functions of the human central nervous system, including motor control, reward, or reinforcement. |
2021-07-21 |
2023-08-13 |
human |
| Kathleen Carmichael, Rebekah C Evans, Elena Lopez, Lixin Sun, Mantosh Kumar, Jinhui Ding, Zayd M Khaliq, Huaibin Ca. Function and Regulation of ALDH1A1-Positive Nigrostriatal Dopaminergic Neurons in Motor Control and Parkinson's Disease. Frontiers in neural circuits. vol 15. 2021-07-16. PMID:34079441. |
dopamine is an important chemical messenger in the brain, which modulates movement, reward, motivation, and memory. |
2021-07-16 |
2023-08-13 |
Not clear |
| Yuan-Bing Huang, Ze-Gang Ma, Chao Zheng, Xiao-Kuang K Ma, Devin H Taylor, Ming Gao, Ronald J Lukas, Jie W. Levo-tetrahydropalmatine inhibits α4β2 nicotinic receptor response to nicotine in cultured SH-EP1 cells. Acta pharmacologica Sinica. 2021-07-13. PMID:34253876. |
l-tetrahydropalmatine (l-thp) is an active ingredient of the chinese medicinal herb corydalis ambigua that possesses rich neuropharmacological actions on dopamine (da) receptors in the mesocorticolimbic dopaminergic reward pathway. |
2021-07-13 |
2023-08-13 |
human |
| Samata R Sharma, Xenia Gonda, Peter Dome, Frank I Taraz. What's Love Got to do with it: Role of oxytocin in trauma, attachment and resilience. Pharmacology & therapeutics. vol 214. 2021-07-07. PMID:32512017. |
ot's therapeutic benefits may result from context-dependent interactions with key neural pathways (social, cognitive, and reward), neurotransmitters (dopamine, norepinephrine, serotonin, and endogenous opioids), and biomarkers (adrenocorticotropic hormone, cortisol, and dehydroepiandrosterone sulfate), that lead to a decrease in stress -associated behaviors, and facilitate post-traumatic growth, ultimately leading to increased resilience, through improved social cohesion and attachment. |
2021-07-07 |
2023-08-13 |
Not clear |
| Susan Jone. De-mobilisation of NMDA receptors in midbrain dopamine neurons: a quantum of reward? The Journal of physiology. vol 599. issue 11. 2021-07-07. PMID:33769567. |
de-mobilisation of nmda receptors in midbrain dopamine neurons: a quantum of reward? |
2021-07-07 |
2023-08-13 |
Not clear |
| Nailyam Nasirova, Lely A Quina, Shoshana Novik, Eric E Turne. Genetically Targeted Connectivity Tracing Excludes Dopaminergic Inputs to the Interpeduncular Nucleus from the Ventral Tegmentum and Substantia Nigra. eNeuro. vol 8. issue 3. 2021-07-02. PMID:34088738. |
a working model has emerged in which nicotine use may be determined by the balance of reinforcement mediated in part by nicotine effects on dopamine reward pathways, and an aversive "brake" on nicotine consumption encoded in the mhb-ip pathway. |
2021-07-02 |
2023-08-13 |
Not clear |
| Kyoungjune Pak, Ju Won Seok, Hyun-Yeol Nam, Seongho Seo, Myung Jun Lee, Keunyoung Kim, In Joo Ki. The association of DAT gene methylation with striatal DAT availability in healthy subjects. EJNMMI research. vol 11. issue 1. 2021-06-29. PMID:34120227. |
functioning of nigrostriatal dopaminergic neurons is influenced by the expression of the dopamine transporter (dat), and genetic variations in the gene encoding dat contribute to differences in reward processing. |
2021-06-29 |
2023-08-13 |
human |
| Bowen J Fung, Elissa Sutlief, Marshall G Hussain Shule. Dopamine and the interdependency of time perception and reward. Neuroscience and biobehavioral reviews. vol 125. 2021-06-28. PMID:33652021. |
dopamine and the interdependency of time perception and reward. |
2021-06-28 |
2023-08-13 |
human |