| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| John N J Reynolds, Riccardo Avvisati, Paul D Dodson, Simon D Fisher, Manfred J Oswald, Jeffery R Wickens, Yan-Feng Zhan. Coincidence of cholinergic pauses, dopaminergic activation and depolarisation of spiny projection neurons drives synaptic plasticity in the striatum. Nature communications. vol 13. issue 1. 2022-03-12. PMID:35277506. |
in response to reward and reward-predicting cues, phasic dopamine activity potentiates the efficacy of corticostriatal synapses on spiny projection neurons (spns). |
2022-03-12 |
2023-08-13 |
Not clear |
| Merridee J Lefner, Mariana I Dejeux, Matthew J Wana. Sex differences in behavioral responding and dopamine release during Pavlovian learning. eNeuro. 2022-03-10. PMID:35264461. |
the dopamine response to cues signals differences in reward value in well-trained animals. |
2022-03-10 |
2023-08-13 |
rat |
| Merridee J Lefner, Mariana I Dejeux, Matthew J Wana. Sex differences in behavioral responding and dopamine release during Pavlovian learning. eNeuro. 2022-03-10. PMID:35264461. |
these findings suggest cue-evoked dopamine release conveys differences between outcomes only after extensive training, though it is unclear if this is unique to when cues signal differences in reward rate, or if this is also evident when cues signal differences in other value-related parameters such as reward size. |
2022-03-10 |
2023-08-13 |
rat |
| Merridee J Lefner, Mariana I Dejeux, Matthew J Wana. Sex differences in behavioral responding and dopamine release during Pavlovian learning. eNeuro. 2022-03-10. PMID:35264461. |
multiple training sessions were required before cue-evoked dopamine release signaled differences in reward size. |
2022-03-10 |
2023-08-13 |
rat |
| Merridee J Lefner, Mariana I Dejeux, Matthew J Wana. Sex differences in behavioral responding and dopamine release during Pavlovian learning. eNeuro. 2022-03-10. PMID:35264461. |
reward-evoked dopamine release scaled with reward size, though females displayed lower reward-evoked dopamine responses relative to males. |
2022-03-10 |
2023-08-13 |
rat |
| Tom Chou, Maria R D'Orsogn. A mathematical model of reward-mediated learning in drug addiction. Chaos (Woodbury, N.Y.). vol 32. issue 2. 2022-03-02. PMID:35232044. |
drug-induced dopamine releases activate a biphasic reward response with pleasurable, positive "a-processes" (euphoria, rush) followed by unpleasant, negative "b-processes" (cravings, withdrawal). |
2022-03-02 |
2023-08-13 |
Not clear |
| Andrew J Kesner, Coleman B Calva, Satoshi Ikemot. Seeking motivation and reward: roles of dopamine, hippocampus and supramammillo-septal pathway. Progress in neurobiology. 2022-03-01. PMID:35227866. |
seeking motivation and reward: roles of dopamine, hippocampus and supramammillo-septal pathway. |
2022-03-01 |
2023-08-13 |
Not clear |
| Rubén Palomo, Sally Ozonoff, Gregory S Young, Mercedes Belinchón Carmon. Social orienting and initiated joint attention behaviors in 9 to 12 month old children with autism spectrum disorder: A family home movies study. Autism research : official journal of the International Society for Autism Research. 2022-03-01. PMID:35229983. |
in this model, those deficits are both the earliest behavioral consequences of an alteration in the dopamine reward system balance and the foundation of the social impairments that characterize this neurodevelopmental disorder. |
2022-03-01 |
2023-08-13 |
Not clear |
| Man-Yi Jing, Xiao-Yan Ding, Xiao Han, Tai-Yun Zhao, Min-Min Luo, Ning Wu, Jin Li, Rui Son. Activation of mesocorticolimbic dopamine projections initiates cue-induced reinstatement of reward seeking in mice. Acta pharmacologica Sinica. 2022-02-26. PMID:35217811. |
activation of mesocorticolimbic dopamine projections initiates cue-induced reinstatement of reward seeking in mice. |
2022-02-26 |
2023-08-13 |
mouse |
| Sevag Hamamah, Armin Aghazarian, Anthony Nazaryan, Andras Hajnal, Mihai Covas. Role of Microbiota-Gut-Brain Axis in Regulating Dopaminergic Signaling. Biomedicines. vol 10. issue 2. 2022-02-25. PMID:35203645. |
dopamine is a neurotransmitter that plays a critical role both peripherally and centrally in vital functions such as cognition, reward, satiety, voluntary motor movements, pleasure, and motivation. |
2022-02-25 |
2023-08-13 |
Not clear |
| Atieh Chizari, Rezvan Hassanpour, Saeideh Karimi-Haghighi, Ronak Azizbeigi, Somaye Mesgar, Zahra Mousavi, Abbas Haghparas. Compensatory Role of Insulin in the Extinction but Not Reinstatement of Morphine-Induced Conditioned Place Preference in the Streptozotocin-Induced Diabetic Rats. Neurochemical research. 2022-02-21. PMID:35188597. |
insulin receptors are distributed in the whole brain, including different parts of the reward circuit that modulate dopamine as the primary neurotransmitter implicated in addiction. |
2022-02-21 |
2023-08-13 |
rat |
| Kenji Morita, Ayaka Kat. Dopamine ramps for accurate value learning under uncertainty. Trends in neurosciences. 2022-02-19. PMID:35181147. |
dopamine signals ramping towards reward timings have become widely reported, but their functions remain elusive. |
2022-02-19 |
2023-08-13 |
mouse |
| Chihiro Murayama, Toshiki Iwabuchi, Yasuhiko Kato, Masamichi Yokokura, Taeko Harada, Takafumi Goto, Taishi Tamayama, Yosuke Kameno, Tomoyasu Wakuda, Hitoshi Kuwabara, Atsushi Senju, Sadahiko Nishizawa, Yasuomi Ouchi, Hidenori Yamasu. Extrastriatal dopamine D2/3 receptor binding, functional connectivity, and autism socio-communicational deficits: a PET and fMRI study. Molecular psychiatry. 2022-02-19. PMID:35181754. |
the social motivation hypothesis of autism proposes that social communication symptoms in autism-spectrum disorder (asd) stem from atypical social attention and reward networks, where dopamine acts as a crucial mediator. |
2022-02-19 |
2023-08-13 |
Not clear |
| Chihiro Murayama, Toshiki Iwabuchi, Yasuhiko Kato, Masamichi Yokokura, Taeko Harada, Takafumi Goto, Taishi Tamayama, Yosuke Kameno, Tomoyasu Wakuda, Hitoshi Kuwabara, Atsushi Senju, Sadahiko Nishizawa, Yasuomi Ouchi, Hidenori Yamasu. Extrastriatal dopamine D2/3 receptor binding, functional connectivity, and autism socio-communicational deficits: a PET and fMRI study. Molecular psychiatry. 2022-02-19. PMID:35181754. |
however, despite evidence indicating that individuals with asd show atypical activation in extrastriatal regions while processing reward and social stimuli, no previous studies have measured extrastriatal dopamine d2/3 receptor (d2/3r) availability in asd. |
2022-02-19 |
2023-08-13 |
Not clear |
| Theresa H McKim, Theresa M Desrocher. Reward value enhances sequence monitoring ramping dynamics as ending rewards approach in the rostrolateral prefrontal cortex. eNeuro. 2022-02-16. PMID:35168953. |
these results suggest an active, predictive, and distinctive role for rlpfc in sequence monitoring and integration of reward information, consistent with extant literature demonstrating similar accelerating reward-related dopamine dynamics in regions connected to rlpfc. |
2022-02-16 |
2023-08-13 |
human |
| Yasumi Ohta, Takaaki E Murakami, Mamiko Kawahara, Makito Haruta, Hironari Takehara, Hiroyuki Tashiro, Kiyotaka Sasagawa, Jun Ohta, Metin Akay, Yasemin M Aka. Investigating the Influence of GABA Neurons on Dopamine Neurons in the Ventral Tegmental Area Using Optogenetic Techniques. International journal of molecular sciences. vol 23. issue 3. 2022-02-15. PMID:35163036. |
dopamine (da) is the key regulator of reward behavior. |
2022-02-15 |
2023-08-13 |
mouse |
| James F Cavanagh, Sarah L Olguin, Jo A Talledo, Juliana E Kotz, Benjamin Z Roberts, John A Nungaray, Joyce Sprock, David Gregg, Savita G Bhakta, Gregory A Light, Neal R Swerdlow, Jared W Young, Jonathan L Brigma. Amphetamine alters an EEG marker of reward processing in humans and mice. Psychopharmacology. 2022-02-08. PMID:35132440. |
in sum, the present results confirm the role of dopamine in the generation of the reward positivity in humans, and pave the way toward a pharmacologically valid biomarker of reward sensitivity across species. |
2022-02-08 |
2023-08-13 |
mouse |
| Jillian L Seiler, Caitlin V Cosme, Venus N Sherathiya, Michael D Schaid, Joseph M Bianco, Abigael S Bridgemohan, Talia N Lerne. Dopamine signaling in the dorsomedial striatum promotes compulsive behavior. Current biology : CB. 2022-02-08. PMID:35134327. |
we hypothesized that dopamine, a critical modulator of striatal synaptic plasticity, could control alterations in corticostriatal circuits leading to the development of compulsions (defined here as continued reward seeking in the face of punishment). |
2022-02-08 |
2023-08-13 |
Not clear |
| Jillian L Seiler, Caitlin V Cosme, Venus N Sherathiya, Michael D Schaid, Joseph M Bianco, Abigael S Bridgemohan, Talia N Lerne. Dopamine signaling in the dorsomedial striatum promotes compulsive behavior. Current biology : CB. 2022-02-08. PMID:35134327. |
these results establish dms dopamine signaling as a key controller of the development of compulsive reward seeking. |
2022-02-08 |
2023-08-13 |
Not clear |
| John G Mikhael, HyungGoo R Kim, Naoshige Uchida, Samuel J Gershma. The role of state uncertainty in the dynamics of dopamine. Current biology : CB. 2022-02-03. PMID:35114098. |
conventional models assert that, when a stimulus predicts a reward with fixed delay, dopamine activity during the delay should converge to baseline through learning. |
2022-02-03 |
2023-08-13 |
mouse |