| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marjorie C Gondré-Lewis, Igor Elman, Tanya Alim, Edwin Chapman, Beverlyn Settles-Reaves, Carine Galvao, Mark S Gold, David Baron, Shan Kazmi, Eliot Gardner, Ashim Gupta, Catherine Dennen, Kenneth Blu. Frequency of the Dopamine Receptor D3 (rs6280) vs. Opioid Receptor µ1 (rs1799971) Polymorphic Risk Alleles in Patients with Opioid Use Disorder: A Preponderance of Dopaminergic Mechanisms? Biomedicines. vol 10. issue 4. 2022-04-23. PMID:35453620. |
we propose that an addictive endophenotype may not be entirely specific to the drug of choice but rather may be generalizable to altered brain reward circuits impacting net mesocorticolimbic dopamine release. |
2022-04-23 |
2023-08-13 |
human |
| Vasilios Pallikaras, Peter Shizga. The Convergence Model of Brain Reward Circuitry: Implications for Relief of Treatment-Resistant Depression by Deep-Brain Stimulation of the Medial Forebrain Bundle. Frontiers in behavioral neuroscience. vol 16. 2022-04-18. PMID:35431828. |
a recent study in which rats worked for optogenetic stimulation of midbrain dopamine neurons challenges the series-circuit hypothesis and provides a new model of intracranial self-stimulation in which the myelinated non-dopaminergic neurons and the midbrain dopamine projections access the behavioral final common path for reward seeking via separate, converging routes. |
2022-04-18 |
2023-08-13 |
rat |
| Giulia R Fois, Karl Y Bosque-Cordero, Rafael Vazquez-Torres, Cristina Miliano, Xavier Nogues, Carlos A Jimenez-Rivera, Stéphanie Caille, François George. Locus coeruleus activation during environmental novelty gates cocaine-induced long-term hyperactivity of dopamine neurons. iScience. vol 25. issue 4. 2022-04-18. PMID:35434548. |
however, how exploring a novel environment can interfere with the reward system and control cocaine impact on vta dopamine neuron plasticity is unclear. |
2022-04-18 |
2023-08-13 |
Not clear |
| Diogo F Antunes, Marta C Soares, Michael Taborsk. Dopamine modulates social behaviour in cooperatively breeding fish. Molecular and cellular endocrinology. 2022-04-18. PMID:35436519. |
dopamine is part of the reward system triggering the social decision-making network in the brain. |
2022-04-18 |
2023-08-13 |
Not clear |
| Miriam Schirru, Florence Véronneau-Veilleux, Fahima Nekka, Mauro Ursin. Phasic Dopamine Changes and Hebbian Mechanisms during Probabilistic Reversal Learning in Striatal Circuits: A Computational Study. International journal of molecular sciences. vol 23. issue 7. 2022-04-12. PMID:35408811. |
furthermore, an original mechanism for modulating the phasic dopamine changes is proposed, assuming that the expected reward probability is coded by the activity of the winner go neuron before a reward/punishment takes place. |
2022-04-12 |
2023-08-13 |
Not clear |
| Kenneth Blum, Diwanshu Soni, Rajendra D Badgaiyan, David Baro. Overcoming reward deficiency syndrome by the induction of "dopamine homeostasis" instead of opioids for addiction: illusion or reality? Journal of osteopathic medicine. 2022-04-12. PMID:35411759. |
overcoming reward deficiency syndrome by the induction of "dopamine homeostasis" instead of opioids for addiction: illusion or reality? |
2022-04-12 |
2023-08-13 |
Not clear |
| Kenneth Blum, Diwanshu Soni, Rajendra D Badgaiyan, David Baro. Overcoming reward deficiency syndrome by the induction of "dopamine homeostasis" instead of opioids for addiction: illusion or reality? Journal of osteopathic medicine. 2022-04-12. PMID:35411759. |
it is driven by the imbalance of dopamine and the brain's reward system. |
2022-04-12 |
2023-08-13 |
Not clear |
| Kenneth Blum, Diwanshu Soni, Rajendra D Badgaiyan, David Baro. Overcoming reward deficiency syndrome by the induction of "dopamine homeostasis" instead of opioids for addiction: illusion or reality? Journal of osteopathic medicine. 2022-04-12. PMID:35411759. |
viewing reward deficiency syndrome (rds) through this osteopathic lens can bring about treatments that aim to restore the dopamine homeostasis. |
2022-04-12 |
2023-08-13 |
Not clear |
| Hiroshi Kunugi, Maria Tikhonov. Recent advances in understanding depressive disorder: Possible relevance to brain stimulation therapies. Progress in brain research. vol 270. issue 1. 2022-04-09. PMID:35396024. |
robust evidence on the decreased homovanillic acid in the cerebrospinal fluid (csf) of patients with mdd supports a rationale for therapeutic stimulation of the medial forebrain bundle activating the dopamine reward system. |
2022-04-09 |
2023-08-13 |
Not clear |
| Robert A Phillips, Jennifer J Tuscher, Samantha L Black, Emma Andraka, N Dalton Fitzgerald, Lara Ianov, Jeremy J Da. An atlas of transcriptionally defined cell populations in the rat ventral tegmental area. Cell reports. vol 39. issue 1. 2022-04-06. PMID:35385745. |
while decades of research on vta function have focused on dopamine neurons, recent evidence has identified critical roles for gabaergic and glutamatergic neurons in reward processes. |
2022-04-06 |
2023-08-13 |
rat |
| Artem Savchenko, Carina Müller, Jana Lubec, Damiana Leo, Volker Korz, Leila Afjehi-Sadat, Jovana Malikovic, Fernando J Sialana, Gert Lubec, Ilya Sukhano. The Lack of Dopamine Transporter Is Associated With Conditional Associative Learning Impairments and Striatal Proteomic Changes. Frontiers in psychiatry. vol 13. 2022-04-04. PMID:35370807. |
dopamine (da) is critically involved in different functions of the central nervous system (cns) including control of voluntary movement, affect, reward, sleep, and cognition. |
2022-04-04 |
2023-08-13 |
human |
| Ashley C Parr, Finnegan Calabro, Brenden Tervo-Clemmens, Bart Larsen, Will Foran, Beatriz Lun. Contributions of dopamine-related basal ganglia neurophysiology to the developmental effects of incentives on inhibitory control. Developmental cognitive neuroscience. vol 54. 2022-03-28. PMID:35344773. |
dopamine is known to play a role in signaling rewards and supporting cognition, but its role in the enhancing effects of reward on adolescent cognition and inhibitory control remains unknown. |
2022-03-28 |
2023-08-13 |
Not clear |
| Ashley C Parr, Finnegan Calabro, Brenden Tervo-Clemmens, Bart Larsen, Will Foran, Beatriz Lun. Contributions of dopamine-related basal ganglia neurophysiology to the developmental effects of incentives on inhibitory control. Developmental cognitive neuroscience. vol 54. 2022-03-28. PMID:35344773. |
our results provide novel evidence that basal ganglia neurophysiology supports developmental effects of rewards on cognition, which can inform neurodevelopmental models of the role of dopamine in reward processing during adolescence. |
2022-03-28 |
2023-08-13 |
Not clear |
| Juan Zegers-Delgado, Camila Blanlot, Florencia Calderon, Hector E Yarur, Javier Novoa, Ignacio Vega-Quiroga, Cristian P Bastias, Katia Gyslin. Reactive oxygen species modulate locomotor activity and dopamine extracellular levels induced by amphetamine in rats. Behavioural brain research. 2022-03-25. PMID:35331742. |
the increase of dopamine (da) in the reward system is related to the reinforcing effects of drugs of abuse and hyper locomotion induced by psychostimulants. |
2022-03-25 |
2023-08-13 |
rat |
| Yasmin Olsson, Helga Lidö, Mia Ericson, Bo Söderpal. The glycine-containing dipeptide leucine-glycine raises accumbal dopamine levels in a subpopulation of rats presenting a lower endogenous dopamine tone. Journal of neural transmission (Vienna, Austria : 1996). 2022-03-24. PMID:35322277. |
interventions that elevate glycine levels and target the glycine receptor (glyr) in the nucleus accumbens (nac) reduce ethanol intake in rats, supposedly by acting on the brain reward system via increased basal and attenuated ethanol-induced nac dopamine release. |
2022-03-24 |
2023-08-13 |
mouse |
| Ken W Grasing, Kim Burnell, Alok D. Biphasic reward effects are characteristic of both lorcaserin and drugs of abuse: implications for treatment of substance use disorders. Behavioural pharmacology. 2022-03-24. PMID:35324488. |
in addition to not being effective treatments for cocaine use disorder, both dopamine antagonists and lorcaserin can have biphasic effects on dopamine and reward behavior. |
2022-03-24 |
2023-08-13 |
Not clear |
| Luisa Speranza, Salvatore Pulcrano, Carla Perrone-Capano, Umberto di Porzio, Floriana Volpicell. Music affects functional brain connectivity and is effective in the treatment of neurological disorders. Reviews in the neurosciences. 2022-03-24. PMID:35325516. |
it changes the chemistry of the brain, by inducing the release of neurotransmitters and hormones (dopamine, serotonin, and oxytocin) and activates the reward and prosocial systems. |
2022-03-24 |
2023-08-13 |
human |
| Lauren V Riters, Sharon A Stevenso. Using seasonality and birdsong to understand mechanisms underlying context-appropriate shifts in social motivation and reward. Hormones and behavior. vol 142. 2022-03-21. PMID:35313200. |
here we review evidence demonstrating a key integrative role for the medial preoptic area (mpoa) in the seasonally-appropriate adjustment of behaviors, with seasonal changes in dopamine activity in mpoa adjusting social motivation and changes in opioid activity modifying social reward. |
2022-03-21 |
2023-08-13 |
Not clear |
| Changliang Zhu, Hailiang Li, Xuerui Kong, Yezhong Wang, Tao Sun, Feng Wan. Possible Mechanisms Underlying the Effects of Glucagon-Like Peptide-1 Receptor Agonist on Cocaine Use Disorder. Frontiers in pharmacology. vol 13. 2022-03-18. PMID:35300299. |
increasing preclinical evidence suggests that glp-1ras are promising in regulating dopamine release, dopamine transporter (dat) surface expression and function, mesolimbic reward system and gabaergic neurons, and maladaptive behaviors in animal models of self-administration and conditioned place preference. |
2022-03-18 |
2023-08-13 |
Not clear |
| Ameet S Nagpal, Daniel J Lodge, Jennifer S Potter, Alan Frazer, Robin Tragus, Megan E Curtis, Angela M Boley, Maxim Eckman. Analgesic Effects of Oxycodone in Combination With Risperidone or Ziprasidone: Results From a Pilot Randomized Controlled Trial in Healthy Volunteers. Frontiers in pain research (Lausanne, Switzerland). vol 3. 2022-03-17. PMID:35295795. |
given the role of the mesolimbic dopamine system in opioid reward, blocking dopamine d2 receptors should limit the abuse liability of opioid analgesics. |
2022-03-17 |
2023-08-13 |
human |