| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| John G Mikhael, HyungGoo R Kim, Naoshige Uchida, Samuel J Gershma. The role of state uncertainty in the dynamics of dopamine. Current biology : CB. 2022-02-03. PMID:35114098. |
however, recent studies have found that dopamine ramps up before reward in certain conditions even after learning, thus challenging the conventional models. |
2022-02-03 |
2023-08-13 |
mouse |
| A Maryse Minnaard, Mieneke C M Luijendijk, Annemarie M Baars, Lisa Drost, Geert M J Ramakers, Roger A H Adan, Heidi M B Lesscher, Louk J M J Vanderschure. Increased elasticity of sucrose demand during hyperdopaminergic states in rats. Psychopharmacology. 2022-02-01. PMID:35102422. |
mesocorticolimbic dopamine signalling has been implicated in various processes related to cognition and reward, but its precise role in reward valuation and cost-benefit trade-off decisions remains incompletely understood. |
2022-02-01 |
2023-08-13 |
rat |
| Yasmin Zakiniaeiz, Heather Liu, Hong Gao, Soheila Najafzadeh, Jim Ropchan, Nabeel Nabulsi, Yiyun Huang, David Matuskey, Ming-Kai Chen, Kelly P Cosgrove, Evan D Morri. Nicotine patch alters patterns of cigarette smoking-induced dopamine release: Patterns relate to biomarkers associated with treatment response. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2022-01-31. PMID:35100429. |
nicotine acts on nicotinic-acetylcholine receptors on dopamine terminals to release dopamine in the ventral and dorsal striatum encoding reward and habit formation, respectively. |
2022-01-31 |
2023-08-13 |
Not clear |
| Hong-Ju Yang, Briana J Hempel, Guo-Hua Bi, Yi He, Hai-Ying Zhang, Eliot L Gardner, Zheng-Xiong X. Elevation of extracellular glutamate by blockade of astrocyte glutamate transporters inhibits cocaine reinforcement in rats via a NMDA-GluN2B receptor mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-01-29. PMID:35091501. |
in this study, we systemically evaluated the effects of multiple glutamate transporter (glt) inhibitors on extracellular glutamate and dopamine (da) in the nucleus accumbens (nac), intravenous cocaine self-administration, intracranial brain-stimulation reward, and reinstatement of cocaine seeking in male and female rats. |
2022-01-29 |
2023-08-13 |
rat |
| Samuel F Acuff, Nicholas W Simon, James G Murph. Effort-related decision making and cannabis use among college students. Experimental and clinical psychopharmacology. 2022-01-27. PMID:35084912. |
cannabis exerts an indirect effect on dopamine (da) output in the mesolimbic projection, a circuit implicated in reward processing and effort expenditure, and thus may be associated with aberrant effort-based decision making. |
2022-01-27 |
2023-08-13 |
Not clear |
| K Ledermann, R von Känel, C Berna, H Sprott, M Burckhardt, J Jenewein, E L Garland, C Martin-Sölc. Understanding and restoring dopaminergic function in fibromyalgia patients using a mindfulness-based psychological intervention: a [18F]-DOPA PET study. Study protocol for the FIBRODOPA study-a randomized controlled trial. Trials. vol 22. issue 1. 2022-01-26. PMID:35078536. |
however, little is known about its impact on dopamine (da) function and in particular with regard to da responses to monetary reward in fm. |
2022-01-26 |
2023-08-13 |
Not clear |
| Sakshi, Bikash Chandra Swain, Anand Kant Das, Nitesh Kumar Pathak, Umakanta Tripath. Z-scan analysis and theoretical studies of dopamine under physiological conditions. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. vol 271. 2022-01-23. PMID:35066443. |
dopamine (da) is a widely researched catecholamine best known for its role in motor, motivation, addiction, and reward. |
2022-01-23 |
2023-08-13 |
Not clear |
| Zhi-Bing You, Eliot L Gardner, Ewa Galaj, Allamar R Moore, Tristram Buck, Chloe J Jordan, Bree A Humburg, Guo-Hua Bi, Zheng-Xiong Xi, Lorenzo Leggi. Involvement of the ghrelin system in the maintenance of oxycodone self-administration: converging evidence from endocrine, pharmacologic and transgenic approaches. Molecular psychiatry. 2022-01-22. PMID:35064236. |
acquisition of oxycodone self-administration significantly upregulated ghs-r1a mrna levels in dopamine neurons in the ventral tegmental area (vta), a brain region critical in drug reward. |
2022-01-22 |
2023-08-13 |
mouse |
| Rohan V Bhimani, Ryan Yates, Caroline E Bass, Jinwoo Par. Distinct limbic dopamine regulation across olfactory-tubercle subregions through integration of in vivo fast-scan cyclic voltammetry and optogenetics. Journal of neurochemistry. 2022-01-21. PMID:35061915. |
increasing evidence has highlighted that dense dopamine (da) innervation of the ot from the ventral tegmental area (vta) is implicated in encoding reward, natural reinforcers, and motivated behaviors. |
2022-01-21 |
2023-08-13 |
rat |
| Sandeep Sathyanandan Nair, Vignayanandam Ravindernath Muddapu, V Srinivasa Chakravarth. A Multiscale, Systems-Level, Neuropharmacological Model of Cortico-Basal Ganglia System for Arm Reaching Under Normal, Parkinsonian, and Levodopa Medication Conditions. Frontiers in computational neuroscience. vol 15. 2022-01-20. PMID:35046787. |
there is a modelling tradition that links dopamine to reward and uses reinforcement learning (rl) concepts to model the basal ganglia. |
2022-01-20 |
2023-08-13 |
Not clear |
| Gerald A Deeha. The enduring behavioral and neurobiological effects of a flavor cue paired with alcohol drinking during adolescence on the incentive properties of the flavor cue in adulthood in female alcohol-preferring (P) rats. Drug and alcohol dependence. vol 232. 2022-01-20. PMID:35051698. |
the current study sought to examine the sex- and developmental-dependent effects of adolescent exposure to flavor cues associated with etoh on operant-lick behavior and cue-induced dopamine (da) levels within the nucleus accumbens shell (acbsh; reward structure) in adulthood. |
2022-01-20 |
2023-08-13 |
rat |
| Ornela Kljakic, Helena Janíčková, Miguel Skirzewski, Amy Reichelt, Sara Memar, Salah El Mestikawy, Yulong Li, Lisa M Saksida, Timothy J Bussey, Vania F Prado, Marco A M Prad. Functional dissociation of behavioral effects from acetylcholine and glutamate released from cholinergic striatal interneurons. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36. issue 2. 2022-01-15. PMID:35032355. |
we found that reduced levels of the vacht from cins negatively impacted dopamine signalling in response to reward, and disrupted complex responses in a sequential chain of events. |
2022-01-15 |
2023-08-13 |
mouse |
| Alex Reichenbach, Rachel E Clarke, Romana Stark, Sarah H Lockie, Mathieu Mequinion, Harry Dempsey, Sasha Rawlinson, Felicia Reed, Tara Sepehrizadeh, Michael DeVeer, Astrid C Munder, Juan Nunez-Iglesias, David Spanswick, Randall Mynatt, Alexxai V Kravitz, Christopher V Dayas, Robyn Brown, Zane B Andrew. Metabolic sensing in AgRP neurons integrates homeostatic state with dopamine signalling in the striatum. eLife. vol 11. 2022-01-12. PMID:35018884. |
agouti-related peptide (agrp) neurons increase motivation for food, however whether metabolic sensing of homeostatic state in agrp neurons potentiates motivation by interacting with dopamine reward systems is unexplored. |
2022-01-12 |
2023-08-13 |
Not clear |
| Kaveh Shahveisi, Nasrin Abdoli, Vahid Farnia, Habibolah Khazaie, Mahmoud Hosseini, Hamed Ghazvini, Mehdi Khodamorad. REM sleep deprivation before extinction or reinstatement alters methamphetamine reward memory via D1-like dopamine receptors. Pharmacology, biochemistry, and behavior. 2022-01-06. PMID:34990706. |
rem sleep deprivation before extinction or reinstatement alters methamphetamine reward memory via d1-like dopamine receptors. |
2022-01-06 |
2023-08-13 |
rat |
| Kaveh Shahveisi, Nasrin Abdoli, Vahid Farnia, Habibolah Khazaie, Mahmoud Hosseini, Hamed Ghazvini, Mehdi Khodamorad. REM sleep deprivation before extinction or reinstatement alters methamphetamine reward memory via D1-like dopamine receptors. Pharmacology, biochemistry, and behavior. 2022-01-06. PMID:34990706. |
we aimed to determine whether rem sleep deprivation (rsd) affects extinction and reinstatement of methamphetamine (meth) reward memory in male rats and also to evaluate the possible role of dopamine d1-like and d2-like dopamine (da) receptors in these processes. |
2022-01-06 |
2023-08-13 |
rat |
| Marie-Charlotte Allichon, Vanesa Ortiz, Paula Pousinha, Andry Andrianarivelo, Anna Petitbon, Nicolas Heck, Pierre Trifilieff, Jacques Barik, Peter Vanhoutt. Cell-Type-Specific Adaptions in Striatal Medium-Sized Spiny Neurons and Their Roles in Behavioral Responses to Drugs of Abuse. Frontiers in synaptic neuroscience. vol 13. 2021-12-31. PMID:34970134. |
addictive drugs promote reinforcement by increasing dopamine in the mesocorticolimbic system, which alters excitatory glutamate transmission within the reward circuitry, thereby hijacking reward processing. |
2021-12-31 |
2023-08-13 |
Not clear |
| Marie-Charlotte Allichon, Vanesa Ortiz, Paula Pousinha, Andry Andrianarivelo, Anna Petitbon, Nicolas Heck, Pierre Trifilieff, Jacques Barik, Peter Vanhoutt. Cell-Type-Specific Adaptions in Striatal Medium-Sized Spiny Neurons and Their Roles in Behavioral Responses to Drugs of Abuse. Frontiers in synaptic neuroscience. vol 13. 2021-12-31. PMID:34970134. |
within the reward circuitry, the striatum is a key target structure of drugs of abuse since it is at the crossroad of converging glutamate inputs from limbic, thalamic and cortical regions, encoding components of drug-associated stimuli and environment, and dopamine that mediates reward prediction error and incentive values. |
2021-12-31 |
2023-08-13 |
Not clear |
| Tiziana Romanazzi, Daniele Zanella, Mary Hongying Cheng, Behrgen Smith, Angela M Carter, Aurelio Galli, Ivet Bahar, Elena Boss. Bile Acids Gate Dopamine Transporter Mediated Currents. Frontiers in chemistry. vol 9. 2021-12-27. PMID:34957043. |
sterols such as cholesterol interact with monoamine transporters, including the dopamine (da) transporter (dat) which plays a key role in da neurotransmission and reward. |
2021-12-27 |
2023-08-13 |
Not clear |
| Kenneth Blum, Bruce Steinberg, Marjorie C Gondre-Lewis, David Baron, Edward J Modestino, Rajendra D Badgaiyan, B William Downs, Debasis Bagchi, Raymond Brewer, Thomas McLaughlin, Abdalla Bowirrat, Mark Gol. A Review of DNA Risk Alleles to Determine Epigenetic Repair of mRNA Expression to Prove Therapeutic Effectiveness in Reward Deficiency Syndrome (RDS): Embracing "Precision Behavioral Management". Psychology research and behavior management. vol 14. 2021-12-24. PMID:34949945. |
this approach includes 1) using the genetic addiction risk severity (gars, a 10 candidate polymorphic gene panel shown to predict asi-alcohol and drug severity) to assess early pre-disposition to substance use disorder; 2) using a validated reward deficiency syndrome (rds) questionnaire; 3) utilization of the comprehensive analysis of reported drugs (card™) to assess treatment compliance and abstinence from illicit drugs during treatment, and, importantly; 4) utilization of a "pro-dopamine regulator (kb220)" (via iv or oral [kb220z] delivery systems) to optimize gene expression, restore the balance of the brain reward cascade's neurotransmitter systems and prevent relapse by induction of dopamine homeostasis, and; 5) utilization of targeted dna polymorphic reward genes to direct mrna genetic expression profiling during the treatment process. |
2021-12-24 |
2023-08-13 |
Not clear |
| Kenneth Blum, Bruce Steinberg, Marjorie C Gondre-Lewis, David Baron, Edward J Modestino, Rajendra D Badgaiyan, B William Downs, Debasis Bagchi, Raymond Brewer, Thomas McLaughlin, Abdalla Bowirrat, Mark Gol. A Review of DNA Risk Alleles to Determine Epigenetic Repair of mRNA Expression to Prove Therapeutic Effectiveness in Reward Deficiency Syndrome (RDS): Embracing "Precision Behavioral Management". Psychology research and behavior management. vol 14. 2021-12-24. PMID:34949945. |
incorporation of these events can be applied to not only the under-considered african-american rds community, but all victims of rds, as a demonstration of a paradigm shift that uniquely provides a novel putative "standard of care" based on dna guided precision nutrition therapy to induce "dopamine homeostasis" and rebalance neurotransmitters in the brain reward cascade. |
2021-12-24 |
2023-08-13 |
Not clear |