| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marcin Kaźmierczak, Saleem M Nicol. The arousal-motor hypothesis of dopamine function: evidence that dopamine facilitates reward seeking in part by maintaining arousal. Neuroscience. 2022-07-19. PMID:35853563. |
the arousal-motor hypothesis of dopamine function: evidence that dopamine facilitates reward seeking in part by maintaining arousal. |
2022-07-19 |
2023-08-14 |
rat |
| Marcin Kaźmierczak, Saleem M Nicol. The arousal-motor hypothesis of dopamine function: evidence that dopamine facilitates reward seeking in part by maintaining arousal. Neuroscience. 2022-07-19. PMID:35853563. |
dopamine facilitates approach to reward via its actions on dopamine receptors in the nucleus accumbens. |
2022-07-19 |
2023-08-14 |
rat |
| Marcin Kaźmierczak, Saleem M Nicol. The arousal-motor hypothesis of dopamine function: evidence that dopamine facilitates reward seeking in part by maintaining arousal. Neuroscience. 2022-07-19. PMID:35853563. |
recent evidence indicates that accumbens dopamine also promotes wakefulness and arousal, but the relationship between dopamine's roles in arousal and reward seeking remains unexplored. |
2022-07-19 |
2023-08-14 |
rat |
| Gabriel S Rocha, Marco Aurelio M Freire, Karina M Paiva, Rodrigo F Oliveira, Bianca Norrara, Paulão Leonardo A G Morais, Lucidio C Oliveira, Rovena Clara G J Engelberth, Jeferson S Cavalcante, José Rodolfo L P Cavalcant. Effect of senescence on the tyrosine hydroxylase and S100B immunoreactivity in the nigrostriatal pathway of the rat. Journal of chemical neuroanatomy. 2022-07-09. PMID:35809809. |
dopamine is a key neurotransmitter for the proper functioning of the brain, directly involved in circuitries related with emotions, learning, motivation and reward. |
2022-07-09 |
2023-08-14 |
rat |
| Merridee J Lefner, Claire E Stelly, Kaitlyn M Fonzi, Hector Zurita, Matthew J Wana. Critical periods when dopamine controls behavioral responding during Pavlovian learning. Psychopharmacology. 2022-07-07. PMID:35796814. |
the dopamine response to cues can signal differences in reward value, though this emerges only after significant training. |
2022-07-07 |
2023-08-14 |
Not clear |
| Ryunosuke Amo, Sara Matias, Akihiro Yamanaka, Kenji F Tanaka, Naoshige Uchida, Mitsuko Watabe-Uchid. A gradual temporal shift of dopamine responses mirrors the progression of temporal difference error in machine learning. Nature neuroscience. 2022-07-07. PMID:35798979. |
however, previous studies failed to observe a key prediction of this algorithm: that when an agent associates a cue and a reward that are separated in time, the timing of dopamine signals should gradually move backward in time from the time of the reward to the time of the cue over multiple trials. |
2022-07-07 |
2023-08-14 |
mouse |
| Wei-Yi Ong, Damien Meng-Kiat Leow, Deron R Herr, Crystal Jing-Jing Ye. What Do Randomized Controlled Trials Inform Us About Potential Disease-Modifying Strategies for Parkinson's Disease? Neuromolecular medicine. 2022-07-01. PMID:35776238. |
randomised controlled trials indicate promising effects of mao-b inhibitors, dopamine agonists, nmda receptor antagonists, metabotropic glutamate receptor antagonists, therapies related to improving glucose utilization and energy production, therapies related to reduction of excitotoxicity and oxidative stress, statin use, therapies related to iron chelation, therapies related to the use of phytochemicals, and therapies related to physical exercise and brain reward pathway on slowing pd progression. |
2022-07-01 |
2023-08-14 |
human |
| Abigail Kalmbach, Vanessa Winiger, Nuri Jeong, Arun Asok, Charles R Gallistel, Peter D Balsam, Eleanor H Simpso. Dopamine encodes real-time reward availability and transitions between reward availability states on different timescales. Nature communications. vol 13. issue 1. 2022-07-01. PMID:35778414. |
dopamine encodes real-time reward availability and transitions between reward availability states on different timescales. |
2022-07-01 |
2023-08-14 |
mouse |
| Abigail Kalmbach, Vanessa Winiger, Nuri Jeong, Arun Asok, Charles R Gallistel, Peter D Balsam, Eleanor H Simpso. Dopamine encodes real-time reward availability and transitions between reward availability states on different timescales. Nature communications. vol 13. issue 1. 2022-07-01. PMID:35778414. |
here we show that when mice can earn rewards in the absence but not presence of an auditory cue, dopamine level in the ventral striatum accurately reflects reward availability in real-time over a sustained period (80 s). |
2022-07-01 |
2023-08-14 |
mouse |
| Abigail Kalmbach, Vanessa Winiger, Nuri Jeong, Arun Asok, Charles R Gallistel, Peter D Balsam, Eleanor H Simpso. Dopamine encodes real-time reward availability and transitions between reward availability states on different timescales. Nature communications. vol 13. issue 1. 2022-07-01. PMID:35778414. |
in addition, unpredictable transitions between different states of reward availability are accompanied by rapid (~1-2 s) dopamine transients that deflect negatively at the onset and positively at the offset of the cue. |
2022-07-01 |
2023-08-14 |
mouse |
| Abigail Kalmbach, Vanessa Winiger, Nuri Jeong, Arun Asok, Charles R Gallistel, Peter D Balsam, Eleanor H Simpso. Dopamine encodes real-time reward availability and transitions between reward availability states on different timescales. Nature communications. vol 13. issue 1. 2022-07-01. PMID:35778414. |
this dopamine encoding of reward availability and transitions between reward availability states is not dependent on reward or activity evoked dopamine release, appears before mice learn the task and is sensitive to motivational state. |
2022-07-01 |
2023-08-14 |
mouse |
| Pramod Kaushik, Jérémie Naudé, Surampudi Bapi Raju, Frédéric Alexandr. A VTA GABAergic computational model of dissociated reward prediction error computation in classical conditioning. Neurobiology of learning and memory. 2022-06-30. PMID:35772681. |
classical conditioning is a fundamental learning mechanism where the ventral striatum is generally thought to be the source of inhibition to ventral tegmental area (vta) dopamine neurons when a reward is expected. |
2022-06-30 |
2023-08-14 |
Not clear |
| Pramod Kaushik, Jérémie Naudé, Surampudi Bapi Raju, Frédéric Alexandr. A VTA GABAergic computational model of dissociated reward prediction error computation in classical conditioning. Neurobiology of learning and memory. 2022-06-30. PMID:35772681. |
this model also exhibits other features in classical conditioning namely, progressively decreasing firing for early rewards closer to the actual reward, twin peaks of vta dopamine during training and cancellation of us dopamine after training. |
2022-06-30 |
2023-08-14 |
Not clear |
| Kenneth Blum, Mark S Brodie, Subhash C Pandey, Jean Lud Cadet, Ashim Gupta, Igor Elman, Panayotis K Thanos, Marjorie C Gondre-Lewis, David Baron, Shan Kazmi, Abdalla Bowirrat, Marcelo Febo, Rajendra D Badgaiyan, Eric R Braverman, Catherine A Dennen, Mark S Gol. Researching Mitigation of Alcohol Binge Drinking in Polydrug Abuse: KCNK13 and RASGRF2 Gene(s) Risk Polymorphisms Coupled with Genetic Addiction Risk Severity (GARS) Guiding Precision Pro-Dopamine Regulation. Journal of personalized medicine. vol 12. issue 6. 2022-06-24. PMID:35743793. |
therefore, our group employed a darkness-induced alcohol intake protocol to define the reward deficiency domains of alcohol and other substance use disorders in terms of reward pathways' reduced dopamine signaling and its restoration via specifically-designed therapeutic compounds. |
2022-06-24 |
2023-08-14 |
Not clear |
| Clément Vitrac, Lauriane Nallet-Khosrofian, Maiko Iijima, Mengia-Seraina Rioult-Pedotti, Andreas Luf. Endogenous dopamine transmission is crucial for motor skill recovery after stroke. IBRO neuroscience reports. vol 13. 2022-06-16. PMID:35707766. |
our data indicate that dopamine transmission is important to drive motor rehabilitation after stroke through motivational aspects and ultimately suggest that augmented motivation and reward feedback could be an interesting strategy to increase the effectiveness or rehabilitation. |
2022-06-16 |
2023-08-14 |
rat |
| Jing Cai, Qingchun Ton. Anatomy and Function of Ventral Tegmental Area Glutamate Neurons. Frontiers in neural circuits. vol 16. 2022-06-07. PMID:35669454. |
the ventral tegmental area (vta) is well known for regulating reward consumption, learning, memory, and addiction behaviors through mediating dopamine (da) release in downstream regions. |
2022-06-07 |
2023-08-14 |
Not clear |
| Vincent Paget-Blanc, Marlene E Pfeffer, Marie Pronot, Paul Lapios, Maria-Florencia Angelo, Roman Walle, Fabrice P Cordelières, Florian Levet, Stéphane Claverol, Sabrina Lacomme, Mélina Petrel, Christelle Martin, Vincent Pitard, Véronique De Smedt Peyrusse, Thomas Biederer, David Perrais, Pierre Trifilieff, Etienne Herzo. A synaptomic analysis reveals dopamine hub synapses in the mouse striatum. Nature communications. vol 13. issue 1. 2022-06-06. PMID:35660742. |
dopamine transmission is involved in reward processing and motor control, and its impairment plays a central role in numerous neurological disorders. |
2022-06-06 |
2023-08-14 |
mouse |
| Ilya S Zhukov, Maria A Ptukha, Ekaterina A Zolotoverkhaja, Ekaterina L Sinitca, Ilya Y Tissen, Inessa V Karpova, Anna B Volnova, Raul R Gainetdino. Evaluation of Approach to a Conspecific and Blood Biochemical Parameters in TAAR1 Knockout Mice. Brain sciences. vol 12. issue 5. 2022-05-28. PMID:35625001. |
it is known that the trace amine-associated receptor 1 (taar1) receptor is involved in limbic brain functions by regulating dopamine transmission and putative reward circuitry. |
2022-05-28 |
2023-08-13 |
mouse |
| Olivier Rampin, Audrey Saint Albin Deliot, Christian Ouali, Jasmine Burguet, Elisa Gry, Gaelle Champeil Potokar, Nathalie Jérôme, Olga Davidenko, Nicolas Darcel, Vincent Bombail, Philippe Andrey, Isabelle Deni. Dopamine Modulates the Processing of Food Odour in the Ventral Striatum. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625863. |
since the ventral striatum, at the crossroads of olfactory and reward pathways, receives a rich dopaminergic innervation, we hypothesized that dopamine plays a role in food odour information processing in the ventral striatum. |
2022-05-28 |
2023-08-13 |
rat |
| Soheil Kazemi Roodsari, Yan Cheng, Kirstin M Reed, Laurie L Wellman, Larry D Sanford, Woong-Ki Kim, Ming-Lei Gu. Sleep Disturbance Alters Cocaine-Induced Locomotor Activity: Involvement of Striatal Neuroimmune and Dopamine Signaling. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625897. |
we hypothesize that sf could affect neuroimmune and dopamine signaling in the brain reward circuitry, which might mediate the linkage between sleep disorders and drug addiction. |
2022-05-28 |
2023-08-13 |
mouse |