| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Soo Min Lee, Han Byeol Jang, Yu Fan, Bonghyo Lee, Sang Chan Kim, Kyle B Bills, Scott C Steffensen, Hee Young Ki. Nociceptive stimuli activate the hypothalamus-habenula circuit to inhibit the mesolimbic reward system and cocaine seeking-behaviors. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-10-24. PMID:36280259. |
the mechanism by which nociception affects dopamine (da) signaling and reward is unclear. |
2022-10-24 |
2023-08-14 |
rat |
| Ying Zhang, Dheeraj S Roy, Guoping Fen. Finding pleasure in repetitive behaviors. Neuron. vol 110. issue 20. 2022-10-20. PMID:36265440. |
through their projections to dopamine neurons in the ventral tegmental area, this subpopulation also drives reward and alleviates anxiety. |
2022-10-20 |
2023-08-14 |
Not clear |
| Wen-Liang Zhou, Kristen Kim, Farhan Ali, Steven T Pittenger, Cali A Calarco, Yann S Mineur, Charu Ramakrishnan, Karl Deisseroth, Alex C Kwan, Marina R Picciott. Activity of a direct VTA to ventral pallidum GABA pathway encodes unconditioned reward value and sustains motivation for reward. Science advances. vol 8. issue 42. 2022-10-19. PMID:36260661. |
this vta gaba projection provides information about reward value directly to the vp, likely distinct from the prediction error signal carried by vta dopamine neurons. |
2022-10-19 |
2023-08-14 |
mouse |
| Armando G Salinas, Jacob A Nadel, Yolanda Mateo, Thanh Huynh, Shana M Augustin, Karel Pacak, David M Lovinge. Chronic Ethanol Consumption Alters Presynaptic Regulation of Dorsal Striatal Dopamine Release in C57BL/6J Mice. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232321. |
dopamine has been implicated in neural and behavioral processes involved in reward and reinforcement and is a critical neurotransmitter in aud. |
2022-10-14 |
2023-08-14 |
mouse |
| Anthony M V Jakob, John G Mikhael, Allison E Hamilos, John A Assad, Samuel J Gershma. Dopamine mediates the bidirectional update of interval timing. Behavioral neuroscience. vol 136. issue 5. 2022-10-12. PMID:36222637. |
according to this theory, the timing of the dopamine signal relative to reward delivery dictates whether subjective time speeds up or slows down: early da signals speed up subjective time and late signals slow it down. |
2022-10-12 |
2023-08-14 |
mouse |
| Karolina Farrell, Armin Lak, Aman B Salee. Midbrain dopamine neurons signal phasic and ramping reward prediction error during goal-directed navigation. Cell reports. vol 41. issue 2. 2022-10-12. PMID:36223748. |
midbrain dopamine neurons are involved in reward value learning and have been linked to reward location learning. |
2022-10-12 |
2023-08-14 |
mouse |
| Karolina Farrell, Armin Lak, Aman B Salee. Midbrain dopamine neurons signal phasic and ramping reward prediction error during goal-directed navigation. Cell reports. vol 41. issue 2. 2022-10-12. PMID:36223748. |
by imaging dopamine neural activity as mice learned to actively navigate a closed-loop virtual reality corridor to obtain reward, we observe phasic and pre-reward ramping dopamine activity, which are modulated by learning stage and task engagement. |
2022-10-12 |
2023-08-14 |
mouse |
| Antony D Abraham, Sanne M Casello, Benjamin B Land, Charles Chavki. Optogenetic stimulation of dynorphinergic neurons within the dorsal raphe activate kappa opioid receptors in the ventral tegmental area and ablation of dorsal raphe prodynorphin or kappa receptors in dopamine neurons blocks stress potentiation of cocaine reward. Addiction neuroscience. vol 1. 2022-09-30. PMID:36176476. |
optogenetic stimulation of dynorphinergic neurons within the dorsal raphe activate kappa opioid receptors in the ventral tegmental area and ablation of dorsal raphe prodynorphin or kappa receptors in dopamine neurons blocks stress potentiation of cocaine reward. |
2022-09-30 |
2023-08-14 |
mouse |
| Melissa Jane Maguir. Wired for sound: The effect of sound on the epileptic brain. Seizure. vol 102. 2022-09-30. PMID:36179456. |
the underlying anti-epileptic mechanism of mozart music is currently unknown, but interesting research is moving away from dopamine reward system theories to computational analysis of specific auditory parameters. |
2022-09-30 |
2023-08-14 |
human |
| Kathy Z Dai, In Bae Choi, Ryan Levitt, Mariah B Blegen, Alanna R Kaplan, Aya Matsui, J Hoon Shin, Miriam E Bocarsly, Eleanor H Simpson, Christoph Kellendonk, Veronica A Alvarez, Lauren K Dobb. Dopamine D2 receptors bidirectionally regulate striatal enkephalin expression: Implications for cocaine reward. Cell reports. vol 40. issue 13. 2022-09-28. PMID:36170833. |
dopamine d2 receptors bidirectionally regulate striatal enkephalin expression: implications for cocaine reward. |
2022-09-28 |
2023-08-14 |
mouse |
| Kathy Z Dai, In Bae Choi, Ryan Levitt, Mariah B Blegen, Alanna R Kaplan, Aya Matsui, J Hoon Shin, Miriam E Bocarsly, Eleanor H Simpson, Christoph Kellendonk, Veronica A Alvarez, Lauren K Dobb. Dopamine D2 receptors bidirectionally regulate striatal enkephalin expression: Implications for cocaine reward. Cell reports. vol 40. issue 13. 2022-09-28. PMID:36170833. |
low dopamine d2 receptor (d2r) availability in the striatum can predispose for cocaine abuse; though how low striatal d2rs facilitate cocaine reward is unclear. |
2022-09-28 |
2023-08-14 |
mouse |
| Giovanni Tarantino, Mauro Cataldi, Vincenzo Citr. Could Alcohol Abuse and Dependence on Junk Foods Inducing Obesity and/or Illicit Drug Use Represent Danger to Liver in Young People with Altered Psychological/Relational Spheres or Emotional Problems? International journal of molecular sciences. vol 23. issue 18. 2022-09-23. PMID:36142317. |
recent data show that young people, mainly due to the pressure of some risk factors or due to disrupted interpersonal relationships, utilise greater reward value and display greater sensitivity to the reinforcing properties of "pleasurable stimuli", specifically in those situations in which an enhanced dopamine release is present. |
2022-09-23 |
2023-08-14 |
Not clear |
| Jun Zhu, Pamela M Quizon, Yingying Wang, Charles A Adeniran, Matthew J Strauss, Ana Jimenez Torres, Palak Patel, Thomas J Cirino, Shainnel O Eans, Haylee R Hammond, Laure S Deliscar, Priscilla O'Hara, Surendra K Saini, Edward Ofori, Rakesh H Vekariya, Sixue Zhang, Omar Moukha-Chafiq, Theresa Nguyen, Subramaniam Ananthan, Corinne E Augelli-Szafran, Chang-Guo Zhan, Jay P McLaughli. SRI-32743, a novel allosteric modulator, attenuates HIV-1 Tat protein-induced inhibition of dopamine transporter and alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice. Neuropharmacology. 2022-09-20. PMID:36126727. |
sri-32743, a novel allosteric modulator, attenuates hiv-1 tat protein-induced inhibition of dopamine transporter and alleviates the potentiation of cocaine reward in hiv-1 tat transgenic mice. |
2022-09-20 |
2023-08-14 |
mouse |
| Konstantin Volzhenin, Jean-Pierre Changeux, Guillaume Duma. Multilevel development of cognitive abilities in an artificial neural network. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 39. 2022-09-19. PMID:36122214. |
at the global scale, dopamine appears necessary to properly provide credit assignment despite the temporal delay between perception and reward. |
2022-09-19 |
2023-08-14 |
Not clear |
| Silvia Hoirisch-Clapauc. The Fibrinolytic System in Peripartum Depression. Seminars in thrombosis and hemostasis. 2022-09-16. PMID:36113504. |
tissue plasminogen activator and plasmin also mediate the release of dopamine, a neurotransmitter implicated in motivation and reward. |
2022-09-16 |
2023-08-14 |
Not clear |
| Mijung Yeom, Sora Ahn, Sun-Young Jang, Jae-Hwan Jang, Youngrye Lee, Dae-Hyun Hahm, Hi-Joon Par. Acupuncture attenuates comorbid anxiety- and depressive-like behaviors of atopic dermatitis through modulating neuroadaptation in the brain reward circuit in mice. Biological research. vol 55. issue 1. 2022-09-10. PMID:36088447. |
in addition, biochemical changes in the brain reward regions were investigated by immunoblotting for the expression of tyrosine hydroxylase (th), dopamine d1 receptor (d1r), phospho-dopamine and camp-regulated phosphoprotein-32 kda (pdarpp-32), phospho-camp response element binding protein (pcreb), Δfosb, and brain-derived neurotrophic factor (bdnf) in the nucleus accumbens, dorsolateral striatum, and ventral tegmental area. |
2022-09-10 |
2023-08-14 |
mouse |
| Kenneth Blum, Abdalla Bowirrat, Luis Llanos Gomez, B William Downs, Debasis Bagchi, Debmalya Barh, Edward J Modestino, David Baron, Thomas McLaughlin, Panayotis Thanos, Mauro Ceccanti, Igor Elman, Rajendra D Badgaiyan, Catherine Dennen, Ashim Gupta, Eric R Braverman, Mark S Gol. Why haven't we solved the addiction crisis? Journal of the neurological sciences. vol 442. 2022-09-09. PMID:36084363. |
our model involves a six-hit approach known as the "reward dysregulation syndrome solution system," which can identify addiction risk and target the root cause of addiction, dopamine dysregulation. |
2022-09-09 |
2023-08-14 |
Not clear |
| Daisuke Tsuboi, Takeshi Otsuka, Takushi Shimomura, Md Omar Faruk, Yukie Yamahashi, Mutsuki Amano, Yasuhiro Funahashi, Keisuke Kuroda, Tomoki Nishioka, Kenta Kobayashi, Hiromi Sano, Taku Nagai, Kiyofumi Yamada, Anastasios V Tzingounis, Atsushi Nambu, Yoshihiro Kubo, Yasuo Kawaguchi, Kozo Kaibuch. Dopamine drives neuronal excitability via KCNQ channel phosphorylation for reward behavior. Cell reports. vol 40. issue 10. 2022-09-07. PMID:36070693. |
dopamine drives neuronal excitability via kcnq channel phosphorylation for reward behavior. |
2022-09-07 |
2023-08-14 |
Not clear |
| Daisuke Tsuboi, Takeshi Otsuka, Takushi Shimomura, Md Omar Faruk, Yukie Yamahashi, Mutsuki Amano, Yasuhiro Funahashi, Keisuke Kuroda, Tomoki Nishioka, Kenta Kobayashi, Hiromi Sano, Taku Nagai, Kiyofumi Yamada, Anastasios V Tzingounis, Atsushi Nambu, Yoshihiro Kubo, Yasuo Kawaguchi, Kozo Kaibuch. Dopamine drives neuronal excitability via KCNQ channel phosphorylation for reward behavior. Cell reports. vol 40. issue 10. 2022-09-07. PMID:36070693. |
previously, we reported that dopamine increases d1 receptor (d1r)-expressing medium spiny neuron (msn) excitability and firing rates in the nucleus accumbens (nac) via the pka/rap1/erk pathway to promote reward behavior. |
2022-09-07 |
2023-08-14 |
Not clear |
| Mandakh Bekhbat, Zhihao Li, Namrataa D Mehta, Michael T Treadway, Michael J Lucido, Bobbi J Woolwine, Ebrahim Haroon, Andrew H Miller, Jennifer C Felge. Correction to: Functional connectivity in reward circuitry and symptoms of anhedonia as therapeutic targets in depression with high inflammation: evidence from a dopamine challenge study. Molecular psychiatry. 2022-09-06. PMID:36065017. |
correction to: functional connectivity in reward circuitry and symptoms of anhedonia as therapeutic targets in depression with high inflammation: evidence from a dopamine challenge study. |
2022-09-06 |
2023-08-14 |
Not clear |