| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eleanor Blair Towers, Ivy L Williams, Emaan I Qillawala, Emilie F Rissman, Wendy J Lync. Sex/Gender Differences in the Time-Course for the Development of Substance Use Disorder: A Focus on the Telescoping Effect. Pharmacological reviews. vol 75. issue 2. 2023-02-13. PMID:36781217. |
we also discuss biologic factors that may contribute to the telescoping effect, such as ovarian hormones, and its neurobiological basis focusing on the mesolimbic dopamine reward pathway and the corticomesolimbic glutamatergic pathway considering the critical roles these pathways play in the rewarding/reinforcing effects of addictive drugs and sud. |
2023-02-13 |
2023-08-14 |
Not clear |
| Austin Ganaway, Yoshinori Sunaga, Yasumi Ohta, Jun Ohta, Metin Akay, Yasemin M Aka. Investigating the Modulation of the VTA Neurons in Nicotine-Exposed Pups during Early Maturation Using Optogenetics. International journal of molecular sciences. vol 24. issue 3. 2023-02-11. PMID:36768606. |
the mesolimbic pathway of the brain, also known as the reward pathway, consists of two main areas that regulate dopamine (da) and addiction-related behaviors. |
2023-02-11 |
2023-08-14 |
rat |
| Dardo Tomasi, Peter Manza, Jean Logan, Ehsan Shokri-Kojori, Michele-Vera Yonga, Danielle Kroll, Dana Feldman, Katherine McPherson, Catherine Biesecker, Evan Dennis, Allison Johnson, Kai Yuan, Wen-Tung Wang, John A Butman, Gene-Jack Wang, Nora D Volko. Time-varying SUVr reflects the dynamics of dopamine increases during methylphenidate challenges in humans. Communications biology. vol 6. issue 1. 2023-02-10. PMID:36765261. |
dopamine facilitates cognition and is implicated in reward processing. |
2023-02-10 |
2023-08-14 |
Not clear |
| Dardo Tomasi, Peter Manza, Jean Logan, Ehsan Shokri-Kojori, Michele-Vera Yonga, Danielle Kroll, Dana Feldman, Katherine McPherson, Catherine Biesecker, Evan Dennis, Allison Johnson, Kai Yuan, Wen-Tung Wang, John A Butman, Gene-Jack Wang, Nora D Volko. Time-varying SUVr reflects the dynamics of dopamine increases during methylphenidate challenges in humans. Communications biology. vol 6. issue 1. 2023-02-10. PMID:36765261. |
since methylphenidate's brain uptake is much faster after intravenous than oral intake, we hypothesize that the speed of dopamine increases in the striatum in addition to its amplitude underly drug reward. |
2023-02-10 |
2023-08-14 |
Not clear |
| Breana Channer, Stephanie M Matt, Emily A Nickoloff-Bybel, Vasiliki Pappa, Yash Agarwal, Jason Wickman, Peter J Gaskil. Dopamine, Immunity, and Disease. Pharmacological reviews. vol 75. issue 1. 2023-02-09. PMID:36757901. |
the neurotransmitter dopamine is a key factor in central nervous system (cns) function, regulating many processes including reward, movement, and cognition. |
2023-02-09 |
2023-08-14 |
human |
| Breana Channer, Stephanie M Matt, Emily A Nickoloff-Bybel, Vasiliki Pappa, Yash Agarwal, Jason Wickman, Peter J Gaskil. Dopamine, Immunity, and Disease. Pharmacological reviews. vol 75. issue 1. 2023-02-09. PMID:36757901. |
significance statement: canonically, dopamine is recognized as a neurotransmitter involved in the regulation of movement, cognition, and reward. |
2023-02-09 |
2023-08-14 |
human |
| Jacob L Nudelman, James A Walt. Acute and Lifetime Stress and Psychotic Illness: The Roles of Reward and Salience Networks. Journal of psychiatry and brain science. vol 7. issue 6. 2023-02-06. PMID:36741029. |
we recount how the reward and salience networks of the brain, together with inputs from the dopamine and serotonin neurotransmitter systems, are implicated in both affective reactivity to stress and the symptoms of psychosis, likely mediate the effects of stress and trauma on the symptoms of psychosis and could serve as targets for interventions. |
2023-02-06 |
2023-08-14 |
Not clear |
| Caroline E Freiermuth, David F Kisor, Joshua Lambert, Robert Braun, Jennifer A Frey, Daniel J Bachmann, Jason J Bischof, Michael S Lyons, Michael V Pantalon, Brittany E Punches, Rachel Ancona, Jon E Spragu. Genetic variants associated with opioid use disorder. Clinical pharmacology and therapeutics. 2023-02-06. PMID:36744646. |
we aimed to test the potential association between 180 candidate single nucleotide polymorphisms (snps), 120 of which were related to the dopamine reward pathway and 60 related to pharmacokinetics. |
2023-02-06 |
2023-08-14 |
human |
| Caroline E Freiermuth, David F Kisor, Joshua Lambert, Robert Braun, Jennifer A Frey, Daniel J Bachmann, Jason J Bischof, Michael S Lyons, Michael V Pantalon, Brittany E Punches, Rachel Ancona, Jon E Spragu. Genetic variants associated with opioid use disorder. Clinical pharmacology and therapeutics. 2023-02-06. PMID:36744646. |
variants within the dopamine reward and opioid metabolism pathways have significant positive (drd3, cyp3a5) and negative (cyp3a4, cyp1a2) associations with oud. |
2023-02-06 |
2023-08-14 |
human |
| Daniel F Hill, Robert W Hickman, Alaa Al-Mohammad, Arkadiusz Stasiak, Wolfram Schult. Dopamine signals encode internally determined subjective value regardless of externally indicated reward attributes. bioRxiv : the preprint server for biology. 2023-01-30. PMID:36711724. |
dopamine signals encode internally determined subjective value regardless of externally indicated reward attributes. |
2023-01-30 |
2023-08-14 |
human |
| Daniel F Hill, Robert W Hickman, Alaa Al-Mohammad, Arkadiusz Stasiak, Wolfram Schult. Dopamine signals encode internally determined subjective value regardless of externally indicated reward attributes. bioRxiv : the preprint server for biology. 2023-01-30. PMID:36711724. |
without indications of an agent's private internal value, we do not know whether dopamine neurons, or any reward neurons, encode the internal value. |
2023-01-30 |
2023-08-14 |
human |
| Daniel F Hill, Robert W Hickman, Alaa Al-Mohammad, Arkadiusz Stasiak, Wolfram Schult. Dopamine signals encode internally determined subjective value regardless of externally indicated reward attributes. bioRxiv : the preprint server for biology. 2023-01-30. PMID:36711724. |
responses of midbrain dopamine neurons followed the trial-by-trial variation of bids despite constant, explicitly predicted reward amounts; correspondingly, the dopamine responses were similar when the animal placed similar bids for different reward amounts. |
2023-01-30 |
2023-08-14 |
human |
| Daniel F Hill, Robert W Hickman, Alaa Al-Mohammad, Arkadiusz Stasiak, Wolfram Schult. Dopamine signals encode internally determined subjective value regardless of externally indicated reward attributes. bioRxiv : the preprint server for biology. 2023-01-30. PMID:36711724. |
support vector regression demonstrated accurate prediction of the animal's bids by as few as twenty dopamine neurons, demonstrating the validity of the dopamine code for internal reward value. |
2023-01-30 |
2023-08-14 |
human |
| Daniel F Hill, Robert W Hickman, Alaa Al-Mohammad, Arkadiusz Stasiak, Wolfram Schult. Dopamine signals encode internally determined subjective value regardless of externally indicated reward attributes. bioRxiv : the preprint server for biology. 2023-01-30. PMID:36711724. |
thus, dopamine responses reflect the instantaneous internal subjective reward value rather than the value imposed by external stimuli. |
2023-01-30 |
2023-08-14 |
human |
| D W Zaide. The art of film: Perspective on neural clues to repeated attraction to movie watching. Neuropsychologia. vol 180. 2023-01-21. PMID:36680933. |
the perspective suggests that functions of the mesolimbic "reward pathway" associated with pleasure and joy, the brain regions responding to facial beauty, to pictorial art aesthetics, and to music listening with increased dopamine levels are all recruited in the repeated attraction. |
2023-01-21 |
2023-08-14 |
Not clear |
| Samhwan Kim, Seongtak Kang, Jiyun Choe, Cheil Moon, Hongsoo Choi, Jin-Young Kim, Ji-Woong Cho. A Microfluidic System for Investigating Anticipatory Medication Effects on Dopamine Homeostasis in Dopaminergic Cells. Analytical chemistry. 2023-01-19. PMID:36656793. |
dopamine (da) homeostasis influences emotions, neural circuit development, cognition, and the reward system. |
2023-01-19 |
2023-08-14 |
Not clear |
| Gwen-Jirō Clochard, Aby Mbengue, Clément Mettling, Birane Diouf, Charlotte Faurie, Omar Sene, Emilie Chancerel, Erwan Guichoux, Guillaume Hollard, Michel Raymond, Marc Willinge. The effect of the 7R allele at the DRD4 locus on risk tolerance is independent of background risk in Senegalese fishermen. Scientific reports. vol 13. issue 1. 2023-01-12. PMID:36635358. |
despite the involvement of dopamine in the expectation of reward described by neurobiologists, a gwas study was not able to demonstrate a genetic contribution of genes involved in the dopaminergic pathway in risk attitudes and gene candidate studies gave contrasting results. |
2023-01-12 |
2023-08-14 |
Not clear |
| Jinhee Bae, Sujin Ahn, Doo-Wan Cho, Hyung-Sun Kim, Su-Cheol Han, Heh-In I. Claustral MeCP2 Regulates Methamphetamine-induced Conditioned Place Preference in Cynomolgus Monkey. Experimental neurobiology. vol 31. issue 6. 2023-01-11. PMID:36631847. |
the claustrum is an important region for regulating reward processing where most neurons receive dopamine input; additionally, in this region, mecp2 is also abundantly expressed. |
2023-01-11 |
2023-08-14 |
human |
| Karis Colyer-Patel, Lauren Kuhns, Alix Weidema, Heidi Lesscher, Janna Cousij. Age-dependent Effects of Tobacco Smoke and Nicotine on Cognition and the Brain: A Systematic Review of the Human and Animal Literature Comparing Adolescents and Adults. Neuroscience and biobehavioral reviews. 2023-01-10. PMID:36627063. |
the limited human studies and more extensive yet heterogeneous animal studies, provide preliminary evidence of heightened fear learning, anxiety-related behaviour, reward processing, nicotinic acetylcholinergic receptors expression, dopamine expression and serotonin functioning after adolescent compared to adult exposure. |
2023-01-10 |
2023-08-14 |
human |
| Kenneth Blum, Catherine A Dennen, David Baron, Panayotis K Thanos, Rajendra D Badgaiya. Offering a putative neurobiological "dopamine homeostatic" solution to overcome the perils of the reward deficiency syndrome pandemic: emergence of "precision behavioral management". Annals of translational medicine. vol 10. issue 23. 2023-01-09. PMID:36618806. |
offering a putative neurobiological "dopamine homeostatic" solution to overcome the perils of the reward deficiency syndrome pandemic: emergence of "precision behavioral management". |
2023-01-09 |
2023-08-14 |
Not clear |