| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Izenwasser, C Kornetsk. The effect of amfonelic acid or nisoxetine in combination with morphine on brain-stimulation reward. Pharmacology, biochemistry, and behavior. vol 32. issue 4. 1989-11-07. PMID:2798547. |
the present study was conducted to investigate the effects of amfonelic acid, an indirect dopamine agonist, and nisoxetine, a highly selective norepinephrine uptake blocker, alone and in combination with morphine, on the reward threshold for rewarding electrical intracranial stimulation. |
1989-11-07 |
2023-08-11 |
rat |
| S Izenwasser, C Kornetsk. The effect of amfonelic acid or nisoxetine in combination with morphine on brain-stimulation reward. Pharmacology, biochemistry, and behavior. vol 32. issue 4. 1989-11-07. PMID:2798547. |
further, these results support the hypothesis that dopamine plays a more critical role in mediating brain-stimulation reward than dose norepinephrine. |
1989-11-07 |
2023-08-11 |
rat |
| T Ljungber. Attenuation of water intake and operant responding by dopamine D2 antagonists: raclopride provides important cues for understanding the functional mechanism of action. Pharmacology & toxicology. vol 65. issue 1. 1989-10-18. PMID:2780512. |
the selective dopamine (da) d2 receptor antagonist raclopride was found to attenuate operant lever-pressing with water as reward in a dose dependent manner and more potently than the corresponding consummatory act, i.e. |
1989-10-18 |
2023-08-11 |
Not clear |
| J C Horvitz, A Ettenber. Haloperidol blocks the response-reinstating effects of food reward: a methodology for separating neuroleptic effects on reinforcement and motor processes. Pharmacology, biochemistry, and behavior. vol 31. issue 4. 1989-08-01. PMID:3252277. |
to test the hypothesis that dopamine antagonist drugs attenuate the reinforcing properties of food, rats previously trained to traverse a straight runway for food reward subsequently underwent extinction sessions. |
1989-08-01 |
2023-08-11 |
rat |
| J M Ng Cheong Ton, G A Gerhardt, M Friedemann, A M Etgen, G M Rose, N S Sharpless, E L Gardne. The effects of delta 9-tetrahydrocannabinol on potassium-evoked release of dopamine in the rat caudate nucleus: an in vivo electrochemical and in vivo microdialysis study. Brain research. vol 451. issue 1-2. 1989-07-31. PMID:2855215. |
given the previous extensive evidence for an involvement of portions of the mesotelencephalic da system in mediating the reinforcing and euphorigenic properties of many classes of abused drugs, and in mediating direct electrical brain stimulation reward, we suggest that the presently demonstrated effects of thc on forebrain dopamine function may be related to marijuana's euphorigenic properties and, thus, to its abuse potential. |
1989-07-31 |
2023-08-11 |
rat |
| B T Lett, V L Gran. The hedonic effects of amphetamine and pentobarbital in goldfish. Pharmacology, biochemistry, and behavior. vol 32. issue 1. 1989-07-17. PMID:2734346. |
however, there is convincing evidence that amphetamine produces a rewarding effect in rats, monkeys and humans by increasing the synaptic concentration of dopamine in the central reward system. |
1989-07-17 |
2023-08-11 |
rat |
| B D McCarter, L Kokkinidi. The effects of long-term administration of antidepressant drugs on intracranial self-stimulation responding in rats. Pharmacology, biochemistry, and behavior. vol 31. issue 2. 1989-06-06. PMID:3244702. |
the implications of these findings were discussed in terms of the effects of these drugs on reward processes and the role of dopamine in the therapeutic efficacy of antidepressant drugs. |
1989-06-06 |
2023-08-11 |
rat |
| L Hernandez, B G Hoebe. Feeding and hypothalamic stimulation increase dopamine turnover in the accumbens. Physiology & behavior. vol 44. issue 4-5. 1989-05-05. PMID:3237847. |
this suggests that accumbens dopamine may be related to sensory input, feeding reflexes, food reward or memory processes and not just to the consummatory act itself. |
1989-05-05 |
2023-08-11 |
rat |
| R A Wise, P P Rompr. Brain dopamine and reward. Annual review of psychology. vol 40. 1989-04-24. PMID:2648975. |
brain dopamine and reward. |
1989-04-24 |
2023-08-11 |
Not clear |
| R A Wise, P P Rompr. Brain dopamine and reward. Annual review of psychology. vol 40. 1989-04-24. PMID:2648975. |
one thing is clear: dopamine is not the only reward transmitter, and dopaminergic neurons are not the final common path for all rewards. |
1989-04-24 |
2023-08-11 |
Not clear |
| R A Wise, P P Rompr. Brain dopamine and reward. Annual review of psychology. vol 40. 1989-04-24. PMID:2648975. |
it is clear that reward circuitry is multisynaptic, and since dopamine cells do not send axons to each other or receive axons from each other, dopamine can at best serve as but a single link in this circuitry. |
1989-04-24 |
2023-08-11 |
Not clear |
| R A Wise, P P Rompr. Brain dopamine and reward. Annual review of psychology. vol 40. 1989-04-24. PMID:2648975. |
as we have seen in the case of midline mesencephalic stimulation, the location of the electrode tip in relation to the dopamine cells and fibers tells us little about the role of dopamine in brain stimulation reward. |
1989-04-24 |
2023-08-11 |
Not clear |
| R A Wise, P P Rompr. Brain dopamine and reward. Annual review of psychology. vol 40. 1989-04-24. PMID:2648975. |
it seems clear that the ventral tegmental dopamine system plays a critical role in midline mesencephalic reward, despite the distance from the electrode tip to the dopamine cells where morphine causes its dopamine-dependent facilitory effects or to the dopamine terminals where low-dose neuroleptics presumably cause theirs. |
1989-04-24 |
2023-08-11 |
Not clear |
| R A Wise, P P Rompr. Brain dopamine and reward. Annual review of psychology. vol 40. 1989-04-24. PMID:2648975. |
it is not consistent with the dopamine hypothesis that dopamine-independent reward sites should exist in these areas, since any reward signals carried to nucleus accumbens or frontal cortex by dopamine fibers would-unless we are to believe that reward "happens" at these sites-have to be carried to the next stage of the circuit by nondopaminergic fibers (there are no dopaminergic cell bodies in any of the dopamine terminal areas). |
1989-04-24 |
2023-08-11 |
Not clear |
| R P Hamme. Cocaine alters opiate receptor binding in critical brain reward regions. Synapse (New York, N.Y.). vol 3. issue 1. 1989-04-04. PMID:2537540. |
although cocaine action in the central nervous system is usually associated with altered dopamine function, we observed that opiate receptor density as labeled by [3h]naloxone was altered by chronic cocaine exposure in critical brain reward regions, including the nucleus accumbens, ventral pallidum, and lateral hypothalamus. |
1989-04-04 |
2023-08-11 |
rat |
| L van Wolfswinkel, W F Seifert, J M van Re. Catecholamines and endogenous opioids in ventral tegmental self-stimulation reward. Pharmacology, biochemistry, and behavior. vol 30. issue 3. 1989-02-23. PMID:3211968. |
in the present experiment, the influence of graded doses of the dopamine antagonist haloperidol and of the agonist cocaine were investigated on electrical self-stimulation reward, elicited by electrodes located in the ventral tegmental area. |
1989-02-23 |
2023-08-11 |
rat |
| L van Wolfswinkel, W F Seifert, J M van Re. Catecholamines and endogenous opioids in ventral tegmental self-stimulation reward. Pharmacology, biochemistry, and behavior. vol 30. issue 3. 1989-02-23. PMID:3211968. |
it is concluded that dopamine is involved in the reward of electrical self-stimulation elicited from the ventral tegmental area and that this involvement is independent of endorphin systems, suggesting the existence of separate catecholamine and opioid mechanisms modulating brain reward. |
1989-02-23 |
2023-08-11 |
rat |
| H C Fibiger, A G Phillip. Mesocorticolimbic dopamine systems and reward. Annals of the New York Academy of Sciences. vol 537. 1989-01-23. PMID:3059924. |
mesocorticolimbic dopamine systems and reward. |
1989-01-23 |
2023-08-11 |
Not clear |
| A Gratton, B J Hoffer, G A Gerhard. Effects of electrical stimulation of brain reward sites on release of dopamine in rat: an in vivo electrochemical study. Brain research bulletin. vol 21. issue 2. 1988-12-27. PMID:3263894. |
effects of electrical stimulation of brain reward sites on release of dopamine in rat: an in vivo electrochemical study. |
1988-12-27 |
2023-08-11 |
rat |
| A Gratton, B J Hoffer, G A Gerhard. Effects of electrical stimulation of brain reward sites on release of dopamine in rat: an in vivo electrochemical study. Brain research bulletin. vol 21. issue 2. 1988-12-27. PMID:3263894. |
the purpose of the present study was to determine, using in vivo electrochemistry, if electrical stimulation applied to lateral hypothalamic or ventral tegmental reward sites would elicit changes in extracellular levels of dopamine. |
1988-12-27 |
2023-08-11 |
rat |