| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Xenakis, A Sclafan. The effects of pimozide on the consumption of a palatable saccharin-glucose solution in the rat. Pharmacology, biochemistry, and behavior. vol 15. issue 3. 1981-12-22. PMID:7291247. |
two experiments investigated the role of dopamine in reward mechanisms by examining the effects of the specific dopamine receptor blocker pimozide on drinking behavior in the rat. |
1981-12-22 |
2023-08-12 |
rat |
| C Szostak, T N Tombaug. Use of a fixed consecutive number schedule of reinforcement to investigate the effects of pimozide on behavior controlled by internal and external stimuli. Pharmacology, biochemistry, and behavior. vol 15. issue 4. 1981-12-22. PMID:7291264. |
this conclusion has important implications for theories hypothesizing that dopamine subserves reward processes. |
1981-12-22 |
2023-08-12 |
Not clear |
| T N Tombaugh, H Anisman, J Tombaug. Extinction and dopamine receptor blockade after intermittent reinforcement training: failure to observe functional equivalence. Psychopharmacology. vol 70. issue 1. 1980-12-18. PMID:6775330. |
these results indicate that the pimozide and extinction treatment did not produce functionally equivalent effects, and that the role of dopamine on reward processes should not be inferred from comparisons between pimozide and extinction. |
1980-12-18 |
2023-08-12 |
Not clear |
| T J Cro. Catecholamine reward pathways and schizophrenia: the mechanism of the antipsychotic effect and the site of the primary disturbance. Federation proceedings. vol 38. issue 11. 1979-12-18. PMID:39790. |
two catecholamine-containing pathways, the locus ceruleus system and the dopamine neurons arising from the ventral mid-brain, may be involved in reward. |
1979-12-18 |
2023-08-11 |
Not clear |
| P Zarevics, P E Setle. Simultaneous rate-independent and rate-dependent assessment of intracranial self-stimulation: evidence for the direct involvement of dopamine in brain reinforcement mechanisms. Brain research. vol 169. issue 3. 1979-08-16. PMID:312681. |
decreased reward following treatment with the neuroleptic pimozide, a specific blocker of dopamine receptors, was demonstrated by an elevated 'reward threshold'. |
1979-08-16 |
2023-08-11 |
Not clear |
| P Zarevics, P E Setle. Simultaneous rate-independent and rate-dependent assessment of intracranial self-stimulation: evidence for the direct involvement of dopamine in brain reinforcement mechanisms. Brain research. vol 169. issue 3. 1979-08-16. PMID:312681. |
further, due to the specificity of pimozide, they suggest a direct role for dopamine in the mediation of reward. |
1979-08-16 |
2023-08-11 |
Not clear |
| R J Kat. Inhibition-mediating dopamine receptors and the control of intracranial reward. Psychopharmacology. vol 61. issue 1. 1979-07-28. PMID:108718. |
inhibition-mediating dopamine receptors and the control of intracranial reward. |
1979-07-28 |
2023-08-11 |
Not clear |
| R J Kat. Inhibition-mediating dopamine receptors and the control of intracranial reward. Psychopharmacology. vol 61. issue 1. 1979-07-28. PMID:108718. |
a receptor selective agonist and antagonist of inhibition-mediating dopamine receptors (type ii receptors) produced significant and dose-related alterations in bar-pressing for intracranial reward. |
1979-07-28 |
2023-08-11 |
Not clear |
| D M Atrens, T Ljungberg, U Ungersted. Modulation of reward and aversion processes in the rat diencephalon by neuroleptics: differential effects of clozapine and haloperidol. Psychopharmacology. vol 49. issue 1. 1976-11-01. PMID:822454. |
consequently, the attenuation of self-stimulation produced by haloperidol does not indicate a direct role for dopamine in modulating reward. |
1976-11-01 |
2023-08-11 |
rat |
| D M Atrens, T Ljungberg, U Ungersted. Modulation of reward and aversion processes in the rat diencephalon by neuroleptics: differential effects of clozapine and haloperidol. Psychopharmacology. vol 49. issue 1. 1976-11-01. PMID:822454. |
it is suggested that the attenuation of reward produced by neuroleptics reflects a reduction in noradrenergic transmission, whereas their nonspecific effects reflect their blockade of dopamine receptors. |
1976-11-01 |
2023-08-11 |
rat |
| A G Phillips, D A Carter, H C Fibige. Dopaminergic substrates of intracranial self-stimulation in the caudate-putamen. Brain research. vol 104. issue 2. 1976-07-06. PMID:1260420. |
an extensive mapping of the caudate-putamen in rat for intracranial self-stimulation (ics) site was undertaken to provide addtional support for the role of dopamine in brain-stimulation reward. |
1976-07-06 |
2023-08-11 |
human |
| A G Phillips, D A Carter, H C Fibige. Dopaminergic substrates of intracranial self-stimulation in the caudate-putamen. Brain research. vol 104. issue 2. 1976-07-06. PMID:1260420. |
first, unilateral reduction of neostriatal dopamine is accompanied by a loss of brain-stimulation reward at sites normally innervated by the nsb, specifically the caudate-putamen. |
1976-07-06 |
2023-08-11 |
human |
| E T Rolls, P H Kelly, S G Sha. Noradrenaline, dopamine, and brain-stimulation reward. Pharmacology, biochemistry, and behavior. vol 2. issue 6. 1975-09-24. PMID:4463371. |
noradrenaline, dopamine, and brain-stimulation reward. |
1975-09-24 |
2023-08-11 |
Not clear |
| L Stein, J D Belluzzi, S Ritter, C D Wis. Self-stimulation reward pathways: norepinephrine vs dopamine. Journal of psychiatric research. vol 11. 1975-09-05. PMID:4461783. |
self-stimulation reward pathways: norepinephrine vs dopamine. |
1975-09-05 |
2023-08-11 |
Not clear |
| H C Fibiger, A G Phillip. Role of dopamine and norepinephrine in the chemistry of reward. Journal of psychiatric research. vol 11. 1975-09-05. PMID:4461785. |
role of dopamine and norepinephrine in the chemistry of reward. |
1975-09-05 |
2023-08-11 |
Not clear |
| R A Yokel, R A Wis. Increased lever pressing for amphetamine after pimozide in rats: implications for a dopamine theory of reward. Science (New York, N.Y.). vol 187. issue 4176. 1975-05-13. PMID:1114313. |
increased lever pressing for amphetamine after pimozide in rats: implications for a dopamine theory of reward. |
1975-05-13 |
2023-08-11 |
rat |
| R A Yokel, R A Wis. Increased lever pressing for amphetamine after pimozide in rats: implications for a dopamine theory of reward. Science (New York, N.Y.). vol 187. issue 4176. 1975-05-13. PMID:1114313. |
low and high doses of a dopamine blocking agent had effects on lever pressing for intravenous amphetamine reward which resembled the effects of reward reduction and reward termination, respectively. |
1975-05-13 |
2023-08-11 |
rat |
| R A Yokel, R A Wis. Increased lever pressing for amphetamine after pimozide in rats: implications for a dopamine theory of reward. Science (New York, N.Y.). vol 187. issue 4176. 1975-05-13. PMID:1114313. |
a role in central mediation of reward perception is suggested for dopamine but not for noradrenaline. |
1975-05-13 |
2023-08-11 |
rat |
| B P Posche. Proceedings: Role of norepinephrine, dopamine, and serotonin in intracranial reward. Psychopharmacology bulletin. vol 10. issue 3. 1975-01-16. PMID:4419439. |
proceedings: role of norepinephrine, dopamine, and serotonin in intracranial reward. |
1975-01-16 |
2023-08-11 |
Not clear |
| A S Lippa, S M Antelman, A E Fisher, D R Canfiel. Neurochemical mediation of reward: a significant role for dopamine? Pharmacology, biochemistry, and behavior. vol 1. issue 1. 1974-04-02. PMID:4590600. |
neurochemical mediation of reward: a significant role for dopamine? |
1974-04-02 |
2023-08-11 |
Not clear |