| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christopher A Gadd, Patricia Murtra, Carmen De Felipe, Stephen P Hun. Neurokinin-1 receptor-expressing neurons in the amygdala modulate morphine reward and anxiety behaviors in the mouse. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 23. 2003-10-08. PMID:12967989. |
in a preliminary investigation, bilateral ablation of these neurons from the amygdala, but not the nucleus accumbens and dorsomedial caudate putamen, brought about reductions in morphine reward behavior. |
2003-10-08 |
2023-08-12 |
mouse |
| Michela Andreoli, Michela Tessari, Maria Pilla, Enzo Valerio, Jim J Hagan, Christian A Heidbrede. Selective antagonism at dopamine D3 receptors prevents nicotine-triggered relapse to nicotine-seeking behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 7. 2003-09-02. PMID:12700694. |
drugs of abuse, including, nicotine have been shown to enhance brain reward functions in the mesocortico-limbic dopamine (da) system in general, and the nucleus accumbens in particular. |
2003-09-02 |
2023-08-12 |
rat |
| Eliot L Gardne. Addictive potential of cannabinoids: the underlying neurobiology. Chemistry and physics of lipids. vol 121. issue 1-2. 2003-08-22. PMID:12505706. |
they enhance electrical brain-stimulation reward in the core meso-accumbens reward circuitry of the brain, a circuit encompassing that portion of the medial forebrain bundle (mfb) which links the ventral tegmental area (vta) of the mesencephalic midbrain with the nucleus accumbens (acb) of the ventral limbic forebrain; (2). |
2003-08-22 |
2023-08-12 |
Not clear |
| Laurie H L Sellings, Paul B S Clark. Segregation of amphetamine reward and locomotor stimulation between nucleus accumbens medial shell and core. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 15. 2003-08-13. PMID:12867514. |
segregation of amphetamine reward and locomotor stimulation between nucleus accumbens medial shell and core. |
2003-08-13 |
2023-08-12 |
Not clear |
| Erkki Tupala, Håkan Hall, Tuija Mantere, Pirkko Räsänen, Terttu Särkioja, Jari Tiihone. Dopamine receptors and transporters in the brain reward circuits of type 1 and 2 alcoholics measured with human whole hemisphere autoradiography. NeuroImage. vol 19. issue 1. 2003-07-21. PMID:12781734. |
the role of the dopamine system in brain reward mechanisms and development of substance abuse is well-established with nucleus accumbens as a key structure in mediating these effects. |
2003-07-21 |
2023-08-12 |
human |
| Susan R Sesack, David B Car. Selective prefrontal cortex inputs to dopamine cells: implications for schizophrenia. Physiology & behavior. vol 77. issue 4-5. 2003-07-11. PMID:12526992. |
dopamine (da) neurons in the substantia nigra (sn) and ventral tegmental area (vta) form several projection systems with diverse functions, such as motor planning through the striatum, reward seeking via the nucleus accumbens (nac), and cognitive control through the prefrontal cortex (pfc). |
2003-07-11 |
2023-08-12 |
Not clear |
| Valentina Bassareo, Maria Antonietta De Luca, Marzia Aresu, Alessandra Aste, Teresa Ariu, Gaetano Di Chiar. Differential adaptive properties of accumbens shell dopamine responses to ethanol as a drug and as a motivational stimulus. The European journal of neuroscience. vol 17. issue 7. 2003-06-20. PMID:12713649. |
these observations point to the existence of major differences in the adaptive regulation of nucleus accumbens dopamine transmission in the shell after drug as compared with taste reward. |
2003-06-20 |
2023-08-12 |
human |
| Abraham Zangen, Uri Shale. Nucleus accumbens beta-endorphin levels are not elevated by brain stimulation reward but do increase with extinction. The European journal of neuroscience. vol 17. issue 5. 2003-05-15. PMID:12653982. |
nucleus accumbens beta-endorphin levels are not elevated by brain stimulation reward but do increase with extinction. |
2003-05-15 |
2023-08-12 |
rat |
| Abraham Zangen, Koji Hyod. Transcranial magnetic stimulation induces increases in extracellular levels of dopamine and glutamate in the nucleus accumbens. Neuroreport. vol 13. issue 18. 2003-04-04. PMID:12499837. |
since the nucleus accumbens is a major region implicated in reward circuitry and depressive disorders, we used the microdialysis technique to study some of the neurochemical changes induced in that region during and after acute tms. |
2003-04-04 |
2023-08-12 |
human |
| Jong Y Bahk, Shupeng Li, Moon S Park, Myeong O Ki. Dopamine D1 and D2 receptor mRNA up-regulation in the caudate-putamen and nucleus accumbens of rat brains by smoking. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 6. 2003-03-26. PMID:12452531. |
the neurotransmitter dopamine (da) is important in the reward and reinforcing properties of many addictive drugs: however, the effect of nicotine by cigarette smoking itself on the expression of da receptors in the caudate-putamen (cpu), nucleus accumbens (nac) and olfactory tubercle (otu) has not been elucidated completely. |
2003-03-26 |
2023-08-12 |
rat |
| K P Datla, R G Ahier, A M J Young, J A Gray, M H Josep. Conditioned appetitive stimulus increases extracellular dopamine in the nucleus accumbens of the rat. The European journal of neuroscience. vol 16. issue 10. 2003-03-05. PMID:12453062. |
this study used in vivo microdialysis to examine the release of dopamine (da) in the nucleus accumbens (nac) during the performance of a previously learned, signalled sucrose reward task, and during conditioning of a neutral tone stimulus to this reward. |
2003-03-05 |
2023-08-12 |
rat |
| Darrel J Macey, Hilary R Smith, Michael A Nader, Linda J Porrin. Chronic cocaine self-administration upregulates the norepinephrine transporter and alters functional activity in the bed nucleus of the stria terminalis of the rhesus monkey. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 1. 2003-01-27. PMID:12514195. |
the bed nucleus of the stria terminalis (bnst) is in a key position to influence the integration of motivational and visceral functions, receiving inputs from limbic regions, including the amygdala, and sending projections to areas central to reward processing, including the ventral tegmental area and nucleus accumbens. |
2003-01-27 |
2023-08-12 |
monkey |
| Raúl de la Fuente-Fernández, Anthony G Phillips, Mariangela Zamburlini, Vesna Sossi, Donald B Calne, Thomas J Ruth, A Jon Stoess. Dopamine release in human ventral striatum and expectation of reward. Behavioural brain research. vol 136. issue 2. 2003-01-21. PMID:12429397. |
we conclude that the release of dopamine in the ventral striatum (nucleus accumbens) is related to the expectation of reward and not to the reward itself. |
2003-01-21 |
2023-08-12 |
human |
| James M Brundege, John T William. Differential modulation of nucleus accumbens synapses. Journal of neurophysiology. vol 88. issue 1. 2002-09-06. PMID:12091540. |
the nucleus accumbens (nacc) is a brain region involved in functions ranging from motivation and reward to feeding and drug addiction. |
2002-09-06 |
2023-08-12 |
Not clear |
| S V Al'berti. [Participation of the nucleus accumbens in acquisition of spatial choice behavior in rats performing in a radial plus maze]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 88. issue 5. 2002-08-20. PMID:12136721. |
the results obtained are in good agreement with suggestion that the nucleus accumbens is a site of convergence of spatial information (from hippocampus) with reward information (from amygdala and vta), providing bridge for effective limbic-motor interface underlying motivated goal-directed behavior in animals. |
2002-08-20 |
2023-08-12 |
rat |
| Anh Hai Tran, Ryoi Tamura, Teruko Uwano, Tsuneyuki Kobayashi, Motoya Katsuki, Gen Matsumoto, Taketoshi On. Altered accumbens neural response to prediction of reward associated with place in dopamine D2 receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 13. 2002-07-19. PMID:12084937. |
the nucleus accumbens (nac) plays an important role in the integration of reward with motor function, and it receives dense dopamine innervation and extensive limbic and cortical afferents. |
2002-07-19 |
2023-08-12 |
mouse |
| David Robbe, Gerard Alonso, Severine Chaumont, Joel Bockaert, Olivier J Manzon. Role of p/q-Ca2+ channels in metabotropic glutamate receptor 2/3-dependent presynaptic long-term depression at nucleus accumbens synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 11. 2002-07-05. PMID:12040040. |
the nucleus accumbens (nac) is an important cerebral area involved in reward and spatial memory (pennartz et al., 1994), but little is known about synaptic plasticity in this region. |
2002-07-05 |
2023-08-12 |
Not clear |
| Nora D Volkow, Gene-Jack Wang, Joanna S Fowler, Jean Logan, Millard Jayne, Dinko Franceschi, Cristopher Wong, Samuel J Gatley, Andrew N Gifford, Yu-Shin Ding, Naomi Pappa. "Nonhedonic" food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect. Synapse (New York, N.Y.). vol 44. issue 3. 2002-06-20. PMID:11954049. |
dopamine, a neurotransmitter involved with motivation and reward, its believed to regulate food intake in laboratory animals by modulating its rewarding effects through the nucleus accumbens (na). |
2002-06-20 |
2023-08-12 |
human |
| R D Hur. New medications for nicotine dependence treatment. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 1 Suppl 2. 2002-05-22. PMID:11768177. |
bupropion sustained release (sr) is the first non-nicotine pharmacological treatment approved for smoking cessation and is thought to be effective because of its dopaminergic activity on the pleasure and reward pathways in the mesolimbic system and nucleus accumbens. |
2002-05-22 |
2023-08-12 |
Not clear |
| M Foster Olive, Michelle A Nannini, Christine J Ou, Heather N Koenig, Clyde W Hodg. Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release. European journal of pharmacology. vol 437. issue 1-2. 2002-04-24. PMID:11864639. |
these compounds also delayed or suppressed ethanol-stimulated increases in nucleus accumbens dopamine release, suggesting that acamprosate and homotaurine may reduce ethanol intake by interfering with the ability of ethanol to activate the mesolimbic dopamine reward system. |
2002-04-24 |
2023-08-12 |
rat |