| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Fu, S G Matta, W Gao, B M Shar. Local alpha-bungarotoxin-sensitive nicotinic receptors in the nucleus accumbens modulate nicotine-stimulated dopamine secretion in vivo. Neuroscience. vol 101. issue 2. 2001-02-01. PMID:11074160. |
this fine tuning of the dopamine reward pathway through alpha7 nicotinic cholinergic receptors in the nucleus accumbens may amplify the secretion of dopamine, allowing a subthreshold brain concentration of nicotine to become an effective stimulus for dopamine secretion. |
2001-02-01 |
2023-08-12 |
Not clear |
| D E Comings, K Blu. Reward deficiency syndrome: genetic aspects of behavioral disorders. Progress in brain research. vol 126. 2001-01-18. PMID:11105655. |
the dopaminergic and opioidergic reward pathways of the brain are critical for survival since they provide the pleasure drives for eating, love and reproduction; these are called 'natural rewards' and involve the release of dopamine in the nucleus accumbens and frontal lobes. |
2001-01-18 |
2023-08-12 |
human |
| P D Martin, T On. Effects of reward anticipation, reward presentation, and spatial parameters on the firing of single neurons recorded in the subiculum and nucleus accumbens of freely moving rats. Behavioural brain research. vol 116. issue 1. 2001-01-08. PMID:11090883. |
effects of reward anticipation, reward presentation, and spatial parameters on the firing of single neurons recorded in the subiculum and nucleus accumbens of freely moving rats. |
2001-01-08 |
2023-08-12 |
rat |
| C M Brown, D V Coscina, P J Fletche. The rewarding properties of neuropeptide Y in perifornical hypothalamus vs. nucleus accumbens. Peptides. vol 21. issue 8. 2000-12-28. PMID:11035216. |
to clarify the role of npy in mediating reward processes and the possible interaction between reward and feeding, the present study examined the effects of injecting npy bilaterally into the perifornical hypothalamus (pfh) vs. the nucleus accumbens (nac) on intake of preferred vs. non-preferred food types, as well as on conditioned place preference (cpp) learning. |
2000-12-28 |
2023-08-12 |
Not clear |
| A Ragnauth, V Znamensky, M Moroz, R J Bodna. Analysis of dopamine receptor antagonism upon feeding elicited by mu and delta opioid agonists in the shell region of the nucleus accumbens. Brain research. vol 877. issue 1. 2000-11-28. PMID:10980244. |
the nucleus accumbens (nacc) has been implicated as an important reward site for the mediation of unconditioned reinforcers such as food. |
2000-11-28 |
2023-08-12 |
Not clear |
| B K Tolliver, M W Sganga, F R Shar. Suppression of c-fos induction in the nucleus accumbens prevents acquisition but not expression of morphine-conditioned place preference. The European journal of neuroscience. vol 12. issue 9. 2000-11-07. PMID:10998122. |
the c-fos immediate-early gene is induced by morphine and other drugs of abuse in the nucleus accumbens (nac), a mesolimbic region implicated in drug abuse and reward. |
2000-11-07 |
2023-08-12 |
rat |
| V David, P Cazal. Anatomical and pharmacological specificity of the rewarding effect elicited by microinjections of morphine into the nucleus accumbens of mice. Psychopharmacology. vol 150. issue 1. 2000-10-11. PMID:10867973. |
the involvement of nucleus accumbens (nac) in initiating opiate-induced reward has been difficult to demonstrate in rats, and has not been studied in mice. |
2000-10-11 |
2023-08-12 |
mouse |
| W Hauber, I Bohn, C Giertle. NMDA, but not dopamine D(2), receptors in the rat nucleus accumbens areinvolved in guidance of instrumental behavior by stimuli predicting reward magnitude. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 16. 2000-08-31. PMID:10934279. |
nmda, but not dopamine d(2), receptors in the rat nucleus accumbens areinvolved in guidance of instrumental behavior by stimuli predicting reward magnitude. |
2000-08-31 |
2023-08-12 |
rat |
| W Hauber, I Bohn, C Giertle. NMDA, but not dopamine D(2), receptors in the rat nucleus accumbens areinvolved in guidance of instrumental behavior by stimuli predicting reward magnitude. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 16. 2000-08-31. PMID:10934279. |
the present study sought to explore whether signals transmitted via the nmda subtype of glutamate receptors and via dopamine d(2) receptors in the nucleus accumbens (nac) are critical for the determination of reaction times (rts) of instrumental responses by the expectancy of future reward. |
2000-08-31 |
2023-08-12 |
rat |
| E Fernández-Espej. [How does the nucleus accumbens function?]. Revista de neurologia. vol 30. issue 9. 2000-07-28. PMID:10870199. |
the nucleus accumbens is considered as the neural interface between motivation and action, playing a key role on feeding, sexual, reward, stress-related, drug self-administration behaviors, etc. |
2000-07-28 |
2023-08-12 |
Not clear |
| R M Carelli, S G Ijames, A J Crumlin. Evidence that separate neural circuits in the nucleus accumbens encode cocaine versus "natural" (water and food) reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 11. 2000-06-15. PMID:10818162. |
evidence that separate neural circuits in the nucleus accumbens encode cocaine versus "natural" (water and food) reward. |
2000-06-15 |
2023-08-12 |
rat |
| R M Carelli, S G Ijames, A J Crumlin. Evidence that separate neural circuits in the nucleus accumbens encode cocaine versus "natural" (water and food) reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 11. 2000-06-15. PMID:10818162. |
these findings indicate that in the well-trained animal, cocaine activates a neural circuit in the acb that is largely separate from the circuit that processes information about food and water reward. |
2000-06-15 |
2023-08-12 |
rat |
| M Barrot, M Marinelli, D N Abrous, F Rougé-Pont, M Le Moal, P V Piazz. The dopaminergic hyper-responsiveness of the shell of the nucleus accumbens is hormone-dependent. The European journal of neuroscience. vol 12. issue 3. 2000-05-22. PMID:10762327. |
the dopaminergic projection to the shell of the nucleus accumbens is the most reactive to stress, reward and drugs of abuse and this subregion of the nucleus accumbens is also considered a target of therapeutic effects of atypical antipsychotic drugs (apd). |
2000-05-22 |
2023-08-12 |
rat |
| J W Grimm, R E Se. Dissociation of primary and secondary reward-relevant limbic nuclei in an animal model of relapse. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 22. issue 5. 2000-05-09. PMID:10731622. |
in contrast, ttx inactivation of the nucleus accumbens produced the exact opposite effects, with significant blockade of primary reward (cocaine alone), but not secondary reward (tone + light). |
2000-05-09 |
2023-08-12 |
rat |
| W Schultz, L Tremblay, J R Hollerma. Reward processing in primate orbitofrontal cortex and basal ganglia. Cerebral cortex (New York, N.Y. : 1991). vol 10. issue 3. 2000-04-27. PMID:10731222. |
this article reviews and interprets neuronal activities related to the expectation and delivery of reward in the primate orbitofrontal cortex, in comparison with slowly discharging neurons in the striatum (caudate, putamen and ventral striatum, including nucleus accumbens) and midbrain dopamine neurons. |
2000-04-27 |
2023-08-12 |
Not clear |
| P Zimmermann, C Privou, J P Husto. Differential sensitivity of the caudal and rostral nucleus accumbens to the rewarding effects of a H1-histaminergic receptor blocker as measured with place-preference and self-stimulation behavior. Neuroscience. vol 94. issue 1. 2000-01-14. PMID:10613500. |
the present data also further highlight the nucleus accumbens as functionally heterogenous along its rostrocaudal axis, with the caudal-shell subregion being more sensitive to antihistaminic induced reward than the rostral entity. |
2000-01-14 |
2023-08-12 |
rat |
| T M Tzschentke, W J Schmid. Functional heterogeneity of the rat medial prefrontal cortex: effects of discrete subarea-specific lesions on drug-induced conditioned place preference and behavioural sensitization. The European journal of neuroscience. vol 11. issue 11. 1999-12-28. PMID:10583498. |
while the principal components of the brain reward system, the nucleus accumbens septi and the ventral tegmental area have received much attention, their efferent and afferent structures have not been investigated to the same degree. |
1999-12-28 |
2023-08-12 |
rat |
| M Barrot, M Vallée, M A Gingras, M Le Moal, W Mayo, P V Piazz. The neurosteroid pregnenolone sulphate increases dopamine release and the dopaminergic response to morphine in the rat nucleus accumbens. The European journal of neuroscience. vol 11. issue 10. 1999-12-08. PMID:10564382. |
in this report, we studied the action of preg-s on the activity of the mesencephalic dopaminergic projection to the nucleus accumbens which is considered one of the biological substrates of motivation and reward. |
1999-12-08 |
2023-08-12 |
rat |
| D J Woodward, J Y Chang, P Janak, A Azarov, K Anstro. Mesolimbic neuronal activity across behavioral states. Annals of the New York Academy of Sciences. vol 877. 1999-08-10. PMID:10415645. |
an initial hypothesis was that neural signals would be encountered in the nucleus accumbens and associated regions specifically related to reward. |
1999-08-10 |
2023-08-12 |
Not clear |
| K L Sweet, D B Neil. Amphetamine injections into the nucleus accumbens enhance the reward of stimulation of the subiculum. Annals of the New York Academy of Sciences. vol 877. 1999-08-10. PMID:10415714. |
amphetamine injections into the nucleus accumbens enhance the reward of stimulation of the subiculum. |
1999-08-10 |
2023-08-12 |
Not clear |