| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dean Mobbs, Cindy C Hagan, Eiman Azim, Vinod Menon, Allan L Reis. Personality predicts activity in reward and emotional regions associated with humor. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 45. 2005-12-12. PMID:16275930. |
although neuroticism did not positively correlate with any whole-brain activation, emotional stability (i.e., the inverse of neuroticism) correlated with increased activation in the mesocortical-mesolimbic reward circuitry encompassing the right orbital frontal cortex, caudate, and nucleus accumbens. |
2005-12-12 |
2023-08-12 |
Not clear |
| Jonathan A Hollander, Regina M Carell. Abstinence from cocaine self-administration heightens neural encoding of goal-directed behaviors in the accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 8. 2005-11-29. PMID:15856078. |
the results show that abstinence from cocaine self-administration causes a dramatic increase in the number and strength of acb neurons that encode cocaine-related information, thus representing the first neurophysiological correlate of heightened activation of the 'brain reward system' following abstinence and resumption (relapse) of cocaine consumption. |
2005-11-29 |
2023-08-12 |
rat |
| b' Esa Meririnne, Miina Kajos, Aino Kankaanp\\xc3\\xa4\\xc3\\xa4, Meri Koistinen, Kalervo Kiianmaa, Timo Sepp\\xc3\\xa4l\\xc3\\xa. Rewarding properties of the stereoisomers of 4-methylaminorex: involvement of the dopamine system. Pharmacology, biochemistry, and behavior. vol 81. issue 4. 2005-11-28. PMID:15982727.' |
furthermore, the involvement of the brain dopaminergic system in the 4-methylaminorex reward was tested with the dopamine d1- and d2-receptor antagonists sch 23390 and raclopride administered systemically, or with the neurotoxin 6-hydroxydopamine injected into the nucleus accumbens. |
2005-11-28 |
2023-08-12 |
rat |
| Andrew M J Young, Paula M Moran, Michael H Josep. The role of dopamine in conditioning and latent inhibition: what, when, where and how? Neuroscience and biobehavioral reviews. vol 29. issue 6. 2005-10-27. PMID:16045987. |
it is well established that dopamine is released in the nucleus accumbens (nac) in animals in rewarding or reinforcing situations, and widely believed that this release is the substrate of, or at least closely related to, the experience of reward. |
2005-10-27 |
2023-08-12 |
Not clear |
| Eliot L Gardne. Endocannabinoid signaling system and brain reward: emphasis on dopamine. Pharmacology, biochemistry, and behavior. vol 81. issue 2. 2005-09-08. PMID:15936806. |
the brain's reward circuitry consists of an "in series" circuit of dopaminergic (da) neurons in the ventral tegmental area (vta), nucleus accumbens (acb), and that portion of the medial forebrain bundle (mfb) which links the vta and acb. |
2005-09-08 |
2023-08-12 |
Not clear |
| J-P Gong, Q-R Liu, P-W Zhang, Y Wang, G R Uh. Mouse brain localization of the protein kinase C-enhanced phosphatase 1 inhibitor KEPI (kinase C-enhanced PP1 inhibitor). Neuroscience. vol 132. issue 3. 2005-08-30. PMID:15837133. |
dense kepi immunoreactivity in nucleus accumbens perikarya, combined with evidence for its regulation by opiates, supports possible roles for kepi in molecular signal transduction pathways important for drug reward and addiction. |
2005-08-30 |
2023-08-12 |
mouse |
| Howard C Cromwell, Oum K Hassani, Wolfram Schult. Relative reward processing in primate striatum. Experimental brain research. vol 162. issue 4. 2005-08-18. PMID:15754177. |
the striatum (caudate nucleus, putamen, ventral striatum including nucleus accumbens) is involved in the organization of movement and the processing of reward information. |
2005-08-18 |
2023-08-12 |
Not clear |
| A B Mulder, R Shibata, O Trullier, S I Wiene. Spatially selective reward site responses in tonically active neurons of the nucleus accumbens in behaving rats. Experimental brain research. vol 163. issue 1. 2005-08-17. PMID:15654593. |
spatially selective reward site responses in tonically active neurons of the nucleus accumbens in behaving rats. |
2005-08-17 |
2023-08-12 |
rat |
| David I G Wilson, E M Bowma. Rat nucleus accumbens neurons predominantly respond to the outcome-related properties of conditioned stimuli rather than their behavioral-switching properties. Journal of neurophysiology. vol 94. issue 1. 2005-08-16. PMID:15744003. |
it has been proposed that nucleus accumbens neurons respond to outcome (reward and punishment) and outcome-predictive information. |
2005-08-16 |
2023-08-12 |
rat |
| Edmund J S Sonuga-Bark. Causal models of attention-deficit/hyperactivity disorder: from common simple deficits to multiple developmental pathways. Biological psychiatry. vol 57. issue 11. 2005-07-29. PMID:15949993. |
an alternative model presents adhd as resulting from impaired signaling of delayed rewards arising from disturbances in motivational processes, involving frontoventral striatal reward circuits and mesolimbic branches terminating in the ventral striatum, particularly the nucleus accumbens. |
2005-07-29 |
2023-08-12 |
Not clear |
| Monique Ernst, Eric E Nelson, Sandra Jazbec, Erin B McClure, Christopher S Monk, Ellen Leibenluft, James Blair, Daniel S Pin. Amygdala and nucleus accumbens in responses to receipt and omission of gains in adults and adolescents. NeuroImage. vol 25. issue 4. 2005-07-11. PMID:15850746. |
adolescents' propensity for risk-taking and reward-seeking behaviors suggests a heightened sensitivity for reward, reflected by greater feedback-related activity changes in reward circuitry (e.g., nucleus accumbens), and/or a lower sensitivity to potential harm reflected by weaker feedback-related activity changes in avoidance circuitry (e.g., amygdala) relative to adults. |
2005-07-11 |
2023-08-12 |
Not clear |
| Monique Ernst, Eric E Nelson, Sandra Jazbec, Erin B McClure, Christopher S Monk, Ellen Leibenluft, James Blair, Daniel S Pin. Amygdala and nucleus accumbens in responses to receipt and omission of gains in adults and adolescents. NeuroImage. vol 25. issue 4. 2005-07-11. PMID:15850746. |
responses of nucleus accumbens and amygdala to valenced outcomes (reward receipt and reward omission) were assayed using an event-related functional magnetic resonance imaging procedure paired with a monetary reward task in 14 adults and 16 adolescents. |
2005-07-11 |
2023-08-12 |
Not clear |
| Anna Molander, Bo Söderpal. Accumbal strychnine-sensitive glycine receptors: an access point for ethanol to the brain reward system. Alcoholism, clinical and experimental research. vol 29. issue 1. 2005-05-25. PMID:15654288. |
ethanol (etoh), like other drugs of abuse, increases extracellular dopamine (da) levels in the nucleus accumbens (nac) of the brain reward system, an effect that may be of importance for alcohol addiction. |
2005-05-25 |
2023-08-12 |
Not clear |
| J D Salamone, M Correa, S M Mingote, S M Webe. Beyond the reward hypothesis: alternative functions of nucleus accumbens dopamine. Current opinion in pharmacology. vol 5. issue 1. 2005-05-04. PMID:15661623. |
beyond the reward hypothesis: alternative functions of nucleus accumbens dopamine. |
2005-05-04 |
2023-08-12 |
Not clear |
| Eliyahu Dremencov, Michael E Newman, Noa Kinor, Gitit Blatman-Jan, Cheryl J Schindler, David H Overstreet, Gal Yadi. Hyperfunctionality of serotonin-2C receptor-mediated inhibition of accumbal dopamine release in an animal model of depression is reversed by antidepressant treatment. Neuropharmacology. vol 48. issue 1. 2005-04-28. PMID:15617725. |
dopamine release in the nucleus accumbens mediates motivation and reward, making it a likely candidate to be involved in anhedonia, one of the major symptoms of depression. |
2005-04-28 |
2023-08-12 |
rat |
| Kwang-Ho Choi, Robert L H Clements, Andrew J Greensha. Simultaneous AMPA/kainate receptor blockade and dopamine D(2/3) receptor stimulation in the nucleus accumbens decreases brain stimulation reward in rats. Behavioural brain research. vol 158. issue 1. 2005-04-25. PMID:15680196. |
simultaneous ampa/kainate receptor blockade and dopamine d(2/3) receptor stimulation in the nucleus accumbens decreases brain stimulation reward in rats. |
2005-04-25 |
2023-08-12 |
rat |
| Mitchell F Roitman, Robert A Wheeler, Regina M Carell. Nucleus accumbens neurons are innately tuned for rewarding and aversive taste stimuli, encode their predictors, and are linked to motor output. Neuron. vol 45. issue 4. 2005-04-25. PMID:15721244. |
the nucleus accumbens (nac) is a key component of the brain's reward pathway, yet little is known of how nac cells respond to primary rewarding or aversive stimuli. |
2005-04-25 |
2023-08-12 |
rat |
| James L Goodson, Andrew K Evans, Laura Lindberg, Camryn D Alle. Neuro-evolutionary patterning of sociality. Proceedings. Biological sciences. vol 272. issue 1560. 2005-04-15. PMID:15705546. |
the ieg responses of areas involved in reward (nucleus accumbens and ventral pallidum) and general stress processes (e.g. |
2005-04-15 |
2023-08-12 |
Not clear |
| Hans S Crombag, Grazyna Gorny, Yilin Li, Bryan Kolb, Terry E Robinso. Opposite effects of amphetamine self-administration experience on dendritic spines in the medial and orbital prefrontal cortex. Cerebral cortex (New York, N.Y. : 1991). vol 15. issue 3. 2005-04-05. PMID:15269111. |
we studied the long-term effects of amphetamine self-administration experience (or sucrose reward training) on dendritic morphology (spine density) in nucleus accumbens (nacc), medial (mpc) and orbital prefrontal cortex (ofc), and hippocampus (ca1 and dentate). |
2005-04-05 |
2023-08-12 |
rat |
| Bernard Le Foll, Steven R Goldber. Cannabinoid CB1 receptor antagonists as promising new medications for drug dependence. The Journal of pharmacology and experimental therapeutics. vol 312. issue 3. 2005-04-05. PMID:15525797. |
in particular, they share the common property of activating mesolimbic dopamine brain reward systems, and virtually all abused drugs elevate dopamine levels in the nucleus accumbens. |
2005-04-05 |
2023-08-12 |
Not clear |