| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zheng-Xiong Xi, Jeremy G Gilbert, Xiao-Qing Peng, Arlene C Pak, Xia Li, Eliot L Gardne. Cannabinoid CB1 receptor antagonist AM251 inhibits cocaine-primed relapse in rats: role of glutamate in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 33. 2006-09-12. PMID:16914679. |
given the importance of dopamine, glutamate, and gaba in cocaine reward and relapse, we studied the effects of am251 [n-(piperidin-1-yl)-5-(4-iodophonyl)-1-(2,4-dichlorophenyl)-4-methyl-1h-pyrazole-3-carboxamide], a novel highly selective cb1 receptor antagonist, on cocaine-primed reinstatement of drug-seeking behavior and on cocaine-induced changes in extracellular da, glutamate, and gaba in the nucleus accumbens (nac) under reinstatement conditions. |
2006-09-12 |
2023-08-12 |
rat |
| Kaushik Misra, Subhash C Pande. The decreased cyclic-AMP dependent-protein kinase A function in the nucleus accumbens: a role in alcohol drinking but not in anxiety-like behaviors in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 7. 2006-09-05. PMID:16192983. |
the nucleus accumbens (nac) brain structures have been implicated in the reward and reinforcing properties of ethanol. |
2006-09-05 |
2023-08-12 |
rat |
| Nicole L Schramm-Sapyta, Christopher M Olsen, Danny G Winde. Cocaine self-administration reduces excitatory responses in the mouse nucleus accumbens shell. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 7. 2006-09-05. PMID:16205778. |
previous research examining the effects of intraperitoneally administered cocaine has revealed that cocaine alters excitatory glutamatergic signaling, both directly through regulation of synaptic function, and indirectly through regulation of cellular excitability in areas of the drug reward circuitry such as the nucleus accumbens (nacc) and ventral tegmental area. |
2006-09-05 |
2023-08-12 |
mouse |
| Susana Peciña, Jay Schulkin, Kent C Berridg. Nucleus accumbens corticotropin-releasing factor increases cue-triggered motivation for sucrose reward: paradoxical positive incentive effects in stress? BMC biology. vol 4. 2006-08-16. PMID:16613600. |
nucleus accumbens corticotropin-releasing factor increases cue-triggered motivation for sucrose reward: paradoxical positive incentive effects in stress? |
2006-08-16 |
2023-08-12 |
rat |
| Birgit Abler, Henrik Walter, Susanne Erk, Hannes Kammerer, Manfred Spitze. Prediction error as a linear function of reward probability is coded in human nucleus accumbens. NeuroImage. vol 31. issue 2. 2006-08-14. PMID:16487726. |
prediction error as a linear function of reward probability is coded in human nucleus accumbens. |
2006-08-14 |
2023-08-12 |
human |
| Birgit Abler, Henrik Walter, Susanne Erk, Hannes Kammerer, Manfred Spitze. Prediction error as a linear function of reward probability is coded in human nucleus accumbens. NeuroImage. vol 31. issue 2. 2006-08-14. PMID:16487726. |
first, during the expectation period of the task, the fmri signal in the human nucleus accumbens (nac) increased linearly with the probability of the reward. |
2006-08-14 |
2023-08-12 |
human |
| Tao A Zhang, Adam W Hendricson, Richard A Morriset. Dual synaptic sites of D(1)-dopaminergic regulation of ethanol sensitivity of NMDA receptors in nucleus accumbens. Synapse (New York, N.Y.). vol 58. issue 1. 2006-06-28. PMID:16037948. |
these data suggest that d(1)-like receptors modulate both the presynaptic and postsynaptic effects of ethanol on nmda receptor-mediated synaptic transmission in nucleus accumbens (nac) and that these interactions may contribute to ethanol-induced neuroadaptation of the reward pathway. |
2006-06-28 |
2023-08-12 |
Not clear |
| Kenneth Blum, Brian Meshkin, B William Down. DNA based customized nutraceutical "gene therapy" utilizing a genoscore: a hypothesized paradigm shift of a novel approach to the diagnosis, stratification, prognosis and treatment of inflammatory processes in the human. Medical hypotheses. vol 66. issue 5. 2006-05-25. PMID:16403602. |
we also propose that manipulation of neurochemical reward circuitry in the mesolimbic brain region providing dopamine release at the nucleus accumbens (nac), will have both pain and stress relief benefists, which are a cornerstone to the human inflammatory process. |
2006-05-25 |
2023-08-12 |
human |
| Kanji Yoshimoto, Fumihiko Fukuda, Masafumi Hori, Baku Kato, Hideaki Kato, Hiroyuki Hattori, Naoki Tokuda, Kinya Kuriyama, Tadashi Yano, Masahiro Yasuhar. Acupuncture stimulates the release of serotonin, but not dopamine, in the rat nucleus accumbens. The Tohoku journal of experimental medicine. vol 208. issue 4. 2006-05-09. PMID:16565594. |
a microdialysis guide cannula was implanted into the nucleus accumbens (acc), which plays an important role in the brain reward system. |
2006-05-09 |
2023-08-12 |
rat |
| Virgina M Pickel, Jane Chan, Christopher S Kearn, Kenneth Macki. Targeting dopamine D2 and cannabinoid-1 (CB1) receptors in rat nucleus accumbens. The Journal of comparative neurology. vol 495. issue 3. 2006-04-28. PMID:16440297. |
the nucleus accumbens (acb) shell and core are essential components of neural circuitry mediating the reward and motor effects produced by activation of dopamine d2 or cannabinoid-1 (cb1) receptors. |
2006-04-28 |
2023-08-12 |
rat |
| Guojun Chen, Josef T Kittler, Stephen J Moss, Zhen Ya. Dopamine D3 receptors regulate GABAA receptor function through a phospho-dependent endocytosis mechanism in nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 9. 2006-04-11. PMID:16510729. |
the dopamine d3 receptor, which is highly enriched in nucleus accumbens (nac), has been suggested to play an important role in reinforcement and reward. |
2006-04-11 |
2023-08-12 |
Not clear |
| William A Carlezon, Cécile Béguin, Jennifer A DiNieri, Michael H Baumann, Michele R Richards, Mark S Todtenkopf, Richard B Rothman, Zhongze Ma, David Y-W Lee, Bruce M Cohe. Depressive-like effects of the kappa-opioid receptor agonist salvinorin A on behavior and neurochemistry in rats. The Journal of pharmacology and experimental therapeutics. vol 316. issue 1. 2006-03-31. PMID:16223871. |
at a dose that caused the depressive-like effects in both the fst and icss assays, salva decreased extracellular concentrations of dopamine (da) within the nucleus accumbens (nac), a critical component of brain reward circuitry, without affecting extracellular concentrations of serotonin (5-ht). |
2006-03-31 |
2023-08-12 |
rat |
| Fumihiko Fukuda, Hisashi Shinbara, Kanji Yoshimoto, Tadashi Yano, Kinya Kuriyam. Effect of moxibustion on dopaminergic and serotonergic systems of rat nucleus accumbens. Neurochemical research. vol 30. issue 12. 2006-03-21. PMID:16362780. |
this study examined the effects of moxibustion focusing on the brain reward system, particularly in the nucleus accumbens. |
2006-03-21 |
2023-08-12 |
rat |
| Amy M Naleid, Martha K Grace, David E Cummings, Allen S Levin. Ghrelin induces feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens. Peptides. vol 26. issue 11. 2006-03-09. PMID:16137788. |
ghrelin induces feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens. |
2006-03-09 |
2023-08-12 |
rat |
| Amy M Naleid, Martha K Grace, David E Cummings, Allen S Levin. Ghrelin induces feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens. Peptides. vol 26. issue 11. 2006-03-09. PMID:16137788. |
one of these is the ventral tegmental area (vta), a primary node of the mesolimbic reward pathway, which sends dopaminergic projections to the nucleus accumbens (acb), among other sites. |
2006-03-09 |
2023-08-12 |
rat |
| Yuko Hara, Virginia M Picke. Overlapping intracellular and differential synaptic distributions of dopamine D1 and glutamate N-methyl-D-aspartate receptors in rat nucleus accumbens. The Journal of comparative neurology. vol 492. issue 4. 2006-01-19. PMID:16228995. |
the dopamine d1 receptor (d1r) in the nucleus accumbens (acb) shell is highly implicated in psychostimulant-evoked locomotor activity and reward, whereas the d1r in the acb core is more crucial for appetitive instrumental learning. |
2006-01-19 |
2023-08-12 |
rat |
| Bernard W Ballein. Neural bases of food-seeking: affect, arousal and reward in corticostriatolimbic circuits. Physiology & behavior. vol 86. issue 5. 2006-01-17. PMID:16257019. |
the anticipation of reward on the basis of environmental events exerts a further modulatory influence on food seeking that can be dissociated from that of reward itself; earning a reward and anticipating a reward appear to be distinct processes and have been doubly dissociated at the level of the nucleus accumbens. |
2006-01-17 |
2023-08-12 |
Not clear |
| V Menon, D J Leviti. The rewards of music listening: response and physiological connectivity of the mesolimbic system. NeuroImage. vol 28. issue 1. 2006-01-11. PMID:16023376. |
here, we use functional and effective connectivity analyses to show for the first time that listening to music strongly modulates activity in a network of mesolimbic structures involved in reward processing including the nucleus accumbens (nac) and the ventral tegmental area (vta), as well as the hypothalamus and insula, which are thought to be involved in regulating autonomic and physiological responses to rewarding and emotional stimuli. |
2006-01-11 |
2023-08-12 |
human |
| Rossella Ventura, Antonio Alcaro, Stefano Puglisi-Allegr. Prefrontal cortical norepinephrine release is critical for morphine-induced reward, reinstatement and dopamine release in the nucleus accumbens. Cerebral cortex (New York, N.Y. : 1991). vol 15. issue 12. 2006-01-10. PMID:15728739. |
prefrontal cortical norepinephrine release is critical for morphine-induced reward, reinstatement and dopamine release in the nucleus accumbens. |
2006-01-10 |
2023-08-12 |
Not clear |
| K B Philpot, S Dallvechia-Adams, Y Smith, M J Kuha. A cocaine-and-amphetamine-regulated-transcript peptide projection from the lateral hypothalamus to the ventral tegmental area. Neuroscience. vol 135. issue 3. 2005-12-22. PMID:16154276. |
these findings, combined with the fact that the lateral hypothalamus receives strong inputs from the shell of the nucleus accumbens and ventral pallidum, suggest that these structures are part of integrative functional loops that control reward and appetitive behaviors. |
2005-12-22 |
2023-08-12 |
Not clear |