| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Roy A Wis. Role of brain dopamine in food reward and reinforcement. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 361. issue 1471. 2007-02-15. PMID:16874930. |
while dopaminergic transmission in the nucleus accumbens appears sufficient for some forms of reward, the role of dopamine in food reward does not appear to be restricted to this region. |
2007-02-15 |
2023-08-12 |
mouse |
| P Leão, J C Sousa, M Oliveira, R Silva, O F X Almeida, N Sous. Programming effects of antenatal dexamethasone in the developing mesolimbic pathways. Synapse (New York, N.Y.). vol 61. issue 1. 2007-01-26. PMID:17068773. |
in this study, we examined whether antenatal glucocorticoid exposure induces enduring structural changes in the nucleus accumbens (nacc), an important relay point in the reward limbic circuitry. |
2007-01-26 |
2023-08-12 |
rat |
| George W Hubert, Michael J Kuha. Colocalization of CART peptide with prodynorphin and dopamine D1 receptors in the rat nucleus accumbens. Neuropeptides. vol 40. issue 6. 2007-01-18. PMID:17064765. |
cart peptide is a peptidergic neurotransmitter that is expressed in brain regions involved in critical biological processes such as feeding and stress, and in areas associated with drug reward and abuse including the dopamine-rich nucleus accumbens (nacc), which can be considered part of the basal ganglia. |
2007-01-18 |
2023-08-12 |
rat |
| Y Bureau, M Handa, Y Zhu, F Laliberte, C S Moore, S Liu, Z Huang, D MacDonald, D G Xu, G S Robertso. Neuroanatomical and pharmacological assessment of Fos expression induced in the rat brain by the phosphodiesterase-4 inhibitor 6-(4-pyridylmethyl)-8-(3-nitrophenyl) quinoline. Neuropharmacology. vol 51. issue 5. 2007-01-12. PMID:16901513. |
these findings suggest that pde4 inhibitors produce emesis by increasing nk(1) receptor activation in the ap/nts and implicate brain regions associated with reward and mood such as the amygdala, paraventricular nucleus of the thalamus, habenula and nucleus accumbens in the anti-depressant activity of such compounds. |
2007-01-12 |
2023-08-12 |
rat |
| R Norgren, A Hajnal, S S Mungarnde. Gustatory reward and the nucleus accumbens. Physiology & behavior. vol 89. issue 4. 2007-01-04. PMID:16822531. |
gustatory reward and the nucleus accumbens. |
2007-01-04 |
2023-08-12 |
Not clear |
| R Norgren, A Hajnal, S S Mungarnde. Gustatory reward and the nucleus accumbens. Physiology & behavior. vol 89. issue 4. 2007-01-04. PMID:16822531. |
considerable evidence implicates dopamine in the process of reward and much of the data derives from the nucleus accumbens. |
2007-01-04 |
2023-08-12 |
Not clear |
| Yan Zhou, Jacob Bendor, Lauren Hofmann, Matthew Randesi, Ann Ho, Mary Jeanne Kree. Mu opioid receptor and orexin/hypocretin mRNA levels in the lateral hypothalamus and striatum are enhanced by morphine withdrawal. The Journal of endocrinology. vol 191. issue 1. 2006-12-29. PMID:17065397. |
in this study, we investigated the effects of acute morphine administration, chronic intermittent escalating-dose morphine administration and spontaneous withdrawal from chronic morphine on mrna levels of mu opioid receptor (mop-r), and the opioid peptides pro-opiomelanocortin (pomc) and preprodynorphin (ppdyn) in several key brain regions of the rat, associated with drug reward and motivated behaviors: lateral hypothalamus (lat.hyp), nucleus accumbens (nac) core, amygdala, and caudate-putamen (cpu). |
2006-12-29 |
2023-08-12 |
rat |
| Donald C Cooper, William D Klipec, Melissa A Fowler, Emin D Ozka. A role for the subiculum in the brain motivation/reward circuitry. Behavioural brain research. vol 174. issue 2. 2006-12-20. PMID:16870273. |
the ventral subiculum (vsub) is an interface between the hippocampal formation and structures in the brain reward circuitry, such as the nucleus accumbens (nac) and prefrontal cortex (pfc). |
2006-12-20 |
2023-08-12 |
Not clear |
| Arlene C Pak, Charles R Ashby, Christian A Heidbreder, Maria Pilla, Jeremy Gilbert, Zheng-Xiong Xi, Eliot L Gardne. The selective dopamine D3 receptor antagonist SB-277011A reduces nicotine-enhanced brain reward and nicotine-paired environmental cue functions. The international journal of neuropsychopharmacology. vol 9. issue 5. 2006-12-11. PMID:16942635. |
increasing evidence suggests that enhanced dopamine (da) neurotransmission in the nucleus accumbens (nac) may play a role in mediating the reward and reinforcement produced by addictive drugs and in the attentional processing of drug-associated environmental cues. |
2006-12-11 |
2023-08-12 |
rat |
| Mathew E Brevard, Jerrold S Meyer, Josie A Harder, Craig F Ferri. Imaging brain activity in conscious monkeys following oral MDMA ("ecstasy"). Magnetic resonance imaging. vol 24. issue 6. 2006-12-07. PMID:16824965. |
two key reward areas, the nucleus accumbens and prefrontal cortex, and most other cortical regions showed little activation. |
2006-12-07 |
2023-08-12 |
monkey |
| William J A Eiler, Jacob Masters, Pete F McKay, Lathen Hardy, Josh Goergen, Boikai Mensah-Zoe, Regat Seyoum, Jason Cook, Nathan Johnson, Bethany Neal-Beliveau, Harry L Jun. Amphetamine lowers brain stimulation reward (BSR) threshold in alcohol-preferring (P) and -nonpreferring (NP) rats: regulation by D-sub-1 and D-sub-2 receptors in the nucleus accumbens. Experimental and clinical psychopharmacology. vol 14. issue 3. 2006-12-05. PMID:16893279. |
amphetamine lowers brain stimulation reward (bsr) threshold in alcohol-preferring (p) and -nonpreferring (np) rats: regulation by d-sub-1 and d-sub-2 receptors in the nucleus accumbens. |
2006-12-05 |
2023-08-12 |
rat |
| Michelle A Riley, Ilona Vath. Mid- to late gestational morphine exposure does not alter the rewarding properties of morphine in adult male rats. Neuropharmacology. vol 51. issue 2. 2006-12-04. PMID:16697425. |
both the nucleus accumbens and central amygdala play important roles in modulating drug-induced reward via the mesolimbic dopaminergic system. |
2006-12-04 |
2023-08-12 |
rat |
| Nora D Volkow, Gene-Jack Wang, Yeming Ma, Joanna S Fowler, Christopher Wong, Millard Jayne, Frank Telang, James M Swanso. Effects of expectation on the brain metabolic responses to methylphenidate and to its placebo in non-drug abusing subjects. NeuroImage. vol 32. issue 4. 2006-11-30. PMID:16757181. |
that is, when subjects expected to receive methylphenidate but received placebo there were significant increases in ventral cingulate gyrus (ba 25) and nucleus accumbens (regions involved with emotional reactivity and reward). |
2006-11-30 |
2023-08-12 |
human |
| Mark S Todtenkopf, Aram Parsegian, Alipi Naydenov, Rachael L Neve, Christine Konradi, William A Carlezo. Brain reward regulated by AMPA receptor subunits in nucleus accumbens shell. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 45. 2006-11-28. PMID:17093088. |
drugs of abuse alter expression of ampa-type glutamate receptor subunits (glurs) in the nucleus accumbens (nac), a key component of brain reward systems. |
2006-11-28 |
2023-08-12 |
rat |
| Elena Butovsky, Ana Juknat, Judith Elbaz, Maytal Shabat-Simon, Raya Eilam, Abraham Zangen, Miriam Altstein, Zvi Voge. Chronic exposure to Delta9-tetrahydrocannabinol downregulates oxytocin and oxytocin-associated neurophysin in specific brain areas. Molecular and cellular neurosciences. vol 31. issue 4. 2006-11-22. PMID:16513365. |
; 7 days) to rats, downregulates the expression of oxytocin-neurophysin (ot-np) mrna and of ot and oxytocin-associated np (npot) immunoreactivity in nucleus accumbens (nac) and ventral tegmental area (vta), brain areas involved in reward and addiction. |
2006-11-22 |
2023-08-12 |
rat |
| B J Hoplight, N A Sandygren, J F Neumaie. Increased expression of 5-HT1B receptors in rat nucleus accumbens via virally mediated gene transfer increases voluntary alcohol consumption. Alcohol (Fayetteville, N.Y.). vol 38. issue 2. 2006-11-14. PMID:16839853. |
we hypothesize that these receptors, which are located on the axon terminals of nucleus accumbens' (nacc) projection neurons, modulate alcohol reward mechanisms. |
2006-11-14 |
2023-08-12 |
rat |
| Ashley Acheson, Andrew M Farrar, Michele Patak, Kathryn A Hausknecht, Artur K Kieres, Seulgi Choi, Harriet de Wit, Jerry B Richard. Nucleus accumbens lesions decrease sensitivity to rapid changes in the delay to reinforcement. Behavioural brain research. vol 173. issue 2. 2006-11-01. PMID:16884790. |
to investigate the neural mechanisms that mediate delay discounting, the present study examined the effects of excitotoxic lesions of the nucleus accumbens (nac) on discounting of reward value by delay and probability. |
2006-11-01 |
2023-08-12 |
rat |
| Scott A Huette. Behavioral, but not reward, risk modulates activation of prefrontal, parietal, and insular cortices. Cognitive, affective & behavioral neuroscience. vol 6. issue 2. 2006-10-26. PMID:17007234. |
reward delivery, in comparison with omission, evoked increased activity in the ventromedial prefrontal cortex and the nucleus accumbens. |
2006-10-26 |
2023-08-12 |
human |
| Mark R Stefani, Bita Moghadda. Rule learning and reward contingency are associated with dissociable patterns of dopamine activation in the rat prefrontal cortex, nucleus accumbens, and dorsal striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 34. 2006-09-28. PMID:16928870. |
we measured dopamine release in the prefrontal cortex (pfc), nucleus accumbens (nac), and dorsal striatum (ds) of rats exposed to the same maze apparatus under three behavioral conditions: a set-shift task in which reward depended on discrimination learning and extradimensional set-shifting, a yoked condition in which reward was intermittent and not under the control of the subject, and a "reward-retrieval" variant in which reward was certain on every trial. |
2006-09-28 |
2023-08-12 |
human |
| Mark R Stefani, Bita Moghadda. Rule learning and reward contingency are associated with dissociable patterns of dopamine activation in the rat prefrontal cortex, nucleus accumbens, and dorsal striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 34. 2006-09-28. PMID:16928870. |
thus, the dopaminergic projections to the pfc and nucleus accumbens were selectively, yet differentially, activated in situations of uncertainty and cognitive demand, whereas the dopaminergic projection to the ds responded independently of task differences in learning and reward. |
2006-09-28 |
2023-08-12 |
human |